Diuretics Still Best Treatment for High Blood Pressure Nov 20, 2009
The thiazide-type diuretic chlorthalidone outshone three other treatments -- a calcium channel blocker, an ACE inhibitor and an alpha-receptor blocker -- in most areas, especially in lowering the incidence of stroke and heart failure, according to the most current data from a large ongoing study known as ALLHAT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial) ... The participants were randomly assigned to take one of the following anti-hypertensive drugs:... (MEDLINEplus)
With ARBs, a bigger dose is better for heart failure patients Nov 18, 2009
Standard heart failure treatment guidelines advise doctors to prescribe a diuretic, a beta blocker to ease the heart's workload, and a blood pressure drug called an ACE inhibitor. But many patients can't take ACE inhibitors because of side effects. (USA Today -- News)
Adding Drug Doesn't Help Control Blood Pressure Oct 27, 2009
No risk reduction for heart patients when ARB added to ACE inhibitor therapy, study finds ... FRIDAY, Oct. 23 (HealthDay News) -- Adding an angiotensin receptor blocker (ARB) drug to help control blood pressure has no benefit for people with heart disease who already are taking an ACE inhibitor, a new study finds ... The so-called "meta-analysis" of 41 previous studies found that combination therapy seems no better than ACE inhibitor therapy alone and may be harmful. (MEDLINEplus)
Intensive Dialysis Doesn't Save Lives of the Sickest Oct 23, 2009
A second study in the same issue of the journal found that intensive control of blood pressure using an ACE inhibitor improved kidney function in children aged 3 to 18 with chronic kidney disease. Even though the decrease in blood pressure was considered "modest," the authors stated that "the progression of renal disease was significantly delayed.". (MEDLINEplus)
Strict Blood-Pressure Control and Progression of Renal Failure in Children Oct 22, 2009
Volume 361:1639-1650. The ESCAPE Trial Group. (New England Journal of Medicine)
Micardis Given Wider Approval Oct 21, 2009
For cardiac patients who can't take an ACE inhibitor ... MONDAY, Oct. 19 (HealthDay News) -- Micardis (telmisartan) has received expanded approval from the U.S. Food and Drug Administration to reduce the risk of heart attack or stroke in people 55 or older who cannot take a class of cardiovascular drugs called ACE inhibitors, maker Boehringer Ingelheim said Monday ... Some studies estimate that as many as 20 percent of people taking ACE inhibitors have side effects, which could prevent the... (MEDLINEplus)
Trimming Health-Care Costs Without Reforming the System Oct 2, 2009
His idea: give patients a trio of generic medicines aspirin, a cholesterol-lowering statin, and a blood-pressure-lowering ACE inhibitor. Using Archimedes and thousands of virtual patients, Eddy compared the drug combination to the traditional approach. (BusinessWeek)
A $2.3 billion fine? Thats hitting a mule with a 24 Sep 3, 2009
You can t guess that an ACE inhibitor is going to cause coughing (7-12%) or itching until you try it in an individual. Finn McCool. (Atlanta Journal-Constitution -- Opinion)
Have you consented to prescription drug risks? Sep 1, 2009
" Although damage to eyesight is a relatively rare side effect of amiodarone (Cordarone, Pacerone), it is so serious that patients should be warned about this and other serious adverse effects before they start taking the medicine. If any visual changes are noted, discontinuing the medicine might preserve vision. Other side effects might be less serious, but if they are fairly common, patients should be informed. We have heard from many readers like this one whose doctors failed to mention - or... (Athens Banner-Herald)
Blood Pressure Drug Reverses MS Symptoms in Mice Aug 19, 2009
Lisinopril, also sold by AstraZeneca as Zestril, is an angiotensin-converting enzyme, or ACE inhibitor. It acts by blocking angiotensin, a hormone that makes blood vessels contract, increasing blood pressure. (Newsmax)
Some Blood Pressure Drugs May Block Dementia Jul 25, 2009
ACE inhibitor drugs, a class of drugs that treat high blood pressure, may help protect against dementia ... They looked at whether or not exposure to the general class of drugs known as ACE inhibitors was related to the development of dementia ... But when they looked at individuals treated with centrally active ACE inhibitors, they found a significant cognitive benefit when compared to those who were treated with the non-centrally active drugs. (Newsmax)
The best treatment might be wrong for you Jul 23, 2009
take a two-pronged approach by adding a beta-blocker, ACE inhibitor, or angiotensin II receptor blocker (ARB), all of which work in a manner different from that of your diuretic. Tailor your treatmentIf you have diabetes or kidney problems: Make your second drug an ACE inhibitor, which protects the kidneys ... If you're pregnant: Avoid ACE inhibitors and ARBs; they can cause birth defects. (MSNBC -- Health)
EU Opens Antitrust Case Against Drug Makers Jul 9, 2009
Les Laboratoires Servier developed the blood pressure medication perindopril, a so-called ACE inhibitor. The drug is sold under several brand names, including Coversyl and Aceon. (SmartMoney)
Zast: Finishing last, losing often never felt so good Apr 30, 2009
Regardless, a man would have to be infused with ACE inhibitor optimism to endure such palpitations. Finishing last twice has occurred to 10 other owners in 134 Derbies. (MSNBC -- Sports)
Laughter Remains Good Medicine Apr 18, 2009
Both groups were started on standard medications for diabetes (glipizide, TZD, metformin), hypertension (ACE inhibitor or ARB)) and hyperlipidemia (statins). The researchers followed both groups for 12 months, testing their blood for the stress hormones epinephrine and norepinephrine; HDL cholesterol; inflammatory cytokines TNF- IFN- and IL-6, which contribute to the acceleration of atherosclerosis and C-reactive proteins (hs-CRP), a marker of inflammation and cardiovascular disease. (Science Daily)
TWITTER: Follow us @USATODAYhealth Apr 3, 2009
Matzoh ball soup: The Jewish ACE inhibitor. from. (USA Today -- Tech)
'Miracle heart pill would work' Apr 1, 2009
Adding in an ACE inhibitor did bring extra benefits. Single therapies - beta-blockers alone or ACE inhibitors alone - conferred the least benefit, cutting death risk by only about 20. (BBC News -- Health)
Proteins From Garden Pea May Help Fight High Blood Pressure, Kidney Disease Mar 29, 2009
28, 2009) Researchers in Canada are reporting that proteins found in a common garden pea show promise as a natural food additive or new dietary supplement for fighting high blood pressure and chronic kidney disease (CKD). Those potentially life-threatening conditions affect millions of people worldwide. (Science Daily)
Benazepril plus Amlodipine or Hydrochlorothiazide for Hypertension Mar 12, 2009
Volume 360:1147-1150. Since this article has no abstract, we have provided an extract of the first 100 words of the and any section headings. (New England Journal of Medicine)
Australia approves Ranbaxy drug Mar 7, 2009
Quinapril plus HCTZ, is an ACE inhibitor and is used to treat high blood pressure. Save. (India Times, India -- Intl Business)
Drug Combination Reduces Kidney Disease Risk In Diabetics Mar 2, 2009
"This research demonstrated that lowering blood pressure with an ACE inhibitor/diuretic combination prevents kidney complications, and even cause some early manifestations of kidney disease in people with diabetes regardless of whether their blood pressure is normal or elevated," comments Vlado Perkovic, MBBS, PhD, of The George Institute for International Health in Sydney, Australia, one of the study authors. The two groups were followed up to compare their rates of kidney disease events,... (Science Daily)
Hypertension Drug Dramatically Reduces Proteinuria In Kidney Disease Patients Feb 23, 2009
22, 2009) Taking a much higher than recommended dose of the hypertension drug candesartan cilexetil effectively lowered the amount of protein excreted in the urine of patients with kidney disease, according to a new study. By reducing such proteinuria, the drug could potentially prevent the development of serious complications such as end-stage kidney disease and therefore save many patients' lives. (Science Daily)
Two-Drug Combo May Lower Diabetics' Kidney Risk Feb 21, 2009
A pair of blood pressure medicines helps maintain proper organ function, study suggests. Thursday, February 19, 2009. (MEDLINEplus)
Two-Drug Combo May Lower Diabetics' Kidney Risk Feb 20, 2009
Two-Drug Combo May Lower Diabetics' Kidney Risk - US News and World Report. Friday, February 20, 2009. (U.S. News & World Report)
Blood pressure meds cut kidney disease Feb 19, 2009
Our research demonstrated that lowering blood pressure with an ACE inhibitor (and a) diuretic. reduces the risk of kidney complications by 20 per cent,' says Dr Vlado Perkovic, of The George Institute for International Health. (Sky News Australia)
Healthy People With High Urinary Protein Levels Have Elevated Kidney Disease Risk Feb 13, 2009
13, 2009) Measuring the amount of protein lost in the urine can identify individuals at risk of developing kidney disease, according to a new study. The results suggest that a simple and low-cost urine screen is a promising way to address the epidemic of chronic kidney disease (CKD). (Science Daily)
Blood Pressure Pill Combo More Effective Than Diuretics Feb 7, 2009
The patients took either a tablet containing benazepril (an ACE inhibitor) and amlodipine (a calcium channel blocker) or a tablet that contained benazepril and hydrochloro-thiazide, a type of diuretic (water pill). Both combination pills helped reduce blood pressure in more than 75 percent of patients, but those taking the first pill had 20 percent fewer cardiovascular events than those taking the other combination pill with the diuretic. (MEDLINEplus)