Sex And Lifespan Linked In Worms Jul 25, 2008
"One interesting aspect is that a whole family of compounds is necessary to elicit a biological response. One by itself doesn't do much, but two or three together give a strong response," says Schroeder. Surprisingly, the same group of compounds can also trigger young worms to enter the long-lived dauer stage. (Science Daily)
Culture and depression Jul 15, 2008
As Dr. Bagby explains, "the onset of depression triggers a biological response that takes place within a specific social context, resulting in a cascade of somatic and psychological experiences that are interpreted through a particular cultural lens. Careful translation and adaptation of our assessment tools helped us clarify if different approaches lead to different symptom profiles and conclusions about patients.". Overall, the data demonstrate a consistently greater level of psychological... (EurekAlert!)
Lorus Therapeutics Announces Exclusive Multinational License Agreement with Zoticon Bioventures for Virulizin(R) Apr 9, 2008
Dial in numbers are below: Toronto: 1-416-644-3422 Toll-free: 1-800-732-0232 About Virulizin(R) ------------------ Virulizin(R) is a novel biological response modifier (or immunotherapeutic agent) that stimulates a patient's immune system through several mechanisms, including the activation of macrophages and the infiltration of natural killer cells into tumors. Virulizin(R) has demonstrated high levels of antitumor activity against a number of cancer indications including pancreatic cancer. (PR Newswire)
Two-photon Nanoparticles For The Improved Detection Of Tumor Cells Apr 2, 2008
The latter forms the ligand (molecule binding to the active site of a protein: This binding generally triggers a biological response) recognized by the receptors of HeLa cells (cervical cancer) and MCF7 cells (breast cancer). These results should enable the 3D targeting and imaging of the tumor. (Science Daily)
Tailored Clopidogrel Dosing Improves PCI Outcomes Mar 30, 2008
"This is the first study demonstrating that adjusting the clopidogrel loading dose according to the patient's individual biological response can improve prognosis after percutaneous coronary revascularization," Dr. Bonello said. Dr. Bonello will present the results of this study on Saturday, March 29 at 8:45 a.m. CDT in the Grand Ballroom, S100. (PR Newswire)
Letters to the Editor - 2/25/2008 Feb 26, 2008
Bank Enterprise Award Program; Barry M. Goldwater Scholarship Program; Basic and Applied Scientific Research; Basic Center Grant; Basic, Applied, and Advanced Research in Science and Engineering; Basic/Core Area Health Education Centers; Beach Erosion Control Projects; Beach Monitoring and Notification Program Implementation Grants; Benjamin Gilman International Scholarship; Bilingual/Bicultural Service Demonstration Grants; Bill Emerson Humanitarian Trust; Biobased Transportation Research;... (North County Times)
Predicting Radiation Risk To Astronauts On Columbus, International Space Station Feb 19, 2008
"The main uncertainties in these calculations are our knowledge of the space radiation environment beyond the Earth s magnetic field, and the biological response to radiation," says Ersmark. To provide the environmental information ESA is flying a standard radiation monitor on a number of its spacecraft, including Proba-1, Integral, Rosetta, GIOVE-B, Herschel and Planck. (Science Daily)
* New research says MMR vaccine does not cause autism Feb 7, 2008
The study, which appears in the Archives of Disease in Childhood published by the British Medical Association (BMA), found no evidence of any abnormal biological response from the shot that could point to a link between the vaccine and autism. The investigation by British doctors comes nearly 10 years to the day since a paper, appearing in The Lancet, unleashed a health scare that prompted many parents to refuse the MMR jab for their children. (Taipei Times, Taiwan -- World)
Study: MMR Vaccine Doesn't Cause Autism Feb 5, 2008
The study, published on Tuesday in the Archives of Disease in Childhood, found no evidence of any abnormal biological response from the shot that could point to a link between the vaccine and autism. "This study really supports the view these are safe vaccines," said David Brown, a researcher at Britain's Health Protection Agency who worked on the study. (Newsmax)
CeloNova BioSciences Introduces a New Class of Coronary Stent: The CATANIA(TM) Coronary Stent System with NanoThin Polyzene(R)-F Jan 20, 2008
-- Protection from stent thrombosis -- The Polyzene(R)-F surface treatment is bacterial-resistant "The FDA has cautioned physicians about a small but significant increased risk of stent thrombosis for patients with drug-eluting stents. Now, Britain's National Institute for Health and Clinical Excellence is considering restrictions on DES because they are not cost-effective for most patients and because of uncertainties about safety. Polyzene(R)-F seems to solicit a positive biological response... (PR Newswire)
The Meaning of Color in Fashion Jan 16, 2008
Red also produces a biological response, getting people all hot and bothered by quickening the pulse and increasing the breathing rate. While red is definitely regarded as a sexy color that draws attention, red also makes the wearer look heavier and is an appetite stimulant perhaps this explains common weight gain during the holiday season. (Suite101.com)
Prescription For Addiction Dec 10, 2007
"This tool is different. This tool has a unique and powerful biological response that is very robust," says Dr. Matthew Torrington, the medical director of the Prometa Center of Los Angeles. Dr. Torrington has done addiction research at UCLA. He started prescribing Prometa two years ago. (CBS News)
A French tradition: Why work when you can hibernate? Nov 26, 2007
" It is unlikely this was hibernation in the zoological sense. While extreme cold might have set off a biological response normally seen only in squirrels, bears and marmots, human hibernation probably reflects a sensible, communal decision to stay in bed for as long as possible. But the French seem to have been particularly sleepy. They "hibernated" even in temperate zones. In Burgundy, after the wine harvest, the workers burned the vine stocks, repaired their tools and left the land to the... (International Herald Tribune)
Biomarkers Predict Risk For Invasive Breast Cancer Years Before The Tumor Develops Nov 14, 2007
13, 2007) A specific biological response to cellular stress may predict the likelihood of future tumor formation of the most common, non-invasive form of pre-malignant breast cancer-- ductal carcinoma in situ, or DCIS. ... The research results are also significant because traditional tests available today are not strong enough to predict whether or not a woman will develop a future cancer after diagnosis with DCIS. By identifying this particular biological response in patients, physicians may... (Science Daily)
The REAL Reasons Diets Don't Work Oct 21, 2007
This biological response is the same whether or not the stress is life threatening. In fact, the body responds with over 2500 reactions, which affect every system including metabolism, blood sugar, hormonal function, and appetite (among many, many other things). (Suite101.com)
Renowned specialist joining NM Cancer Center Oct 8, 2007
Prior to founding Cancer Therapeutics, he initiated the National Cancer Institute's Biological Response Modifiers Program and established 's Oncology Division. He holds or has held membership in 19 professional societies. (New Mexico Business Weekly, NM)
Program Alters Kids' Biological Response to Stress Oct 4, 2007
Tuesday, October 2, 2007. NEW YORK (Reuters Health) - Researchers for the first time have evidence that a family intervention known to improve behavior of preschoolers' at risk for antisocial behavior also favorably alters how their bodies react to stressful social situations. (MEDLINEplus)
Early Family Intervention Alters Preschoolers' Biological Response To Stress Oct 3, 2007
Now a new study shows that a non-medical early family intervention that improves caregiving also results in important changes in children's biological response to stress ... Dr. Brotman and her colleagues evaluated whether a program designed to prevent antisocial behavior in high risk preschoolers could alter the children's biological response to a stressful social situation. (Science Daily)
New answers for addiction through science Aug 27, 2007
From the outset, their biological response was the opposite from the majority of the population. Likewise, their withdrawal experience was much more severe and long-lived. (North County Times)
NHS failings over IVF treatment Aug 12, 2007
"This is a biological process and the more we can respond to the biological response the better. "You are more likely to improve your pregnancy rates if you can adapt to the needs of the particular patient. " Big variations According to figures from the regulator, the Human Fertilisation and Embryology Authority, IVF clinic success rates range from around 50% for the best performing clinics to 10% for the worst. Clare Brown, from the patient group Infertility Network UK, said the impact... (BBC News -- UK)
Thwarting Terror: Genes Can Tell the Story of Radiation Exposure Apr 6, 2007
"There's a complex molecular biological response to radiation that seems very unique at different dose levels," Chute says. "The classes of genes that respond are unpredictable and not [generally] overlapping.". (Scientific American)
Green chemistry can help nanotechnology mature, Oregon professor says Feb 19, 2007
Hutchison, who is director of the UOs Material Sciences Institute, is developing diverse libraries of nanoparticles, in which we systematically bury the structural parameters and use in vivo and in vitro assays to determine the relationship between biological response and structural parameters. . (EurekAlert!)
Scientists Identify Gene That May Indicate Predisposition To Schizophrenia Jan 26, 2007
Specifically, their findings identify the chitinase 3-like 1 gene as a potential schizophrenia-susceptibility gene and suggest that the genes involved in biological response to adverse conditions are likely linked to schizophrenia ... support the proposal that genes involved in biological response to adverse environmental conditions play roles in the predisposition to schizophrenia. (Science Daily)
Restarting Tumor-Suppressor Gene May Fight Cancer Jan 25, 2007
Lowe said he also believes that "there are other members of the p53 pathway that can either turn the pathway on or execute the [relevant] biological response. All of them could have a similar biology, and we could imagine tinkering with them to do similar things.". But researchers have their work cut out for them, he said. (Forbes)
SNM: Exploring molecular imaging potential Nov 15, 2006
"Molecular imaging will complement the diagnosis and staging of disease in the absence of anatomic findings, help determine biological response to specific therapeutic agents, lead to an understanding of the pharmacology of new drugs using labeled analogues and initiate exploration of the efficacy of new therapies," said the director of oncologic imaging at Cross Cancer Institute in Edmonton, Alberta, Canada. SNM's first-of-its-kind forum allowed nearly 70 forward-thinking researchers,... (EurekAlert! -- Business News)
Genetic 'Roadmap' Charts Links Between Drugs And Human Disease Oct 3, 2006
The genomic signature of a particular human disease, drug or other biological response of interest serves as the search "word" and potential functional connections are revealed through a rank-ordered list of reference compounds in the database that have matching signatures. One of the surprising results to emerge from the Connectivity Map involves gedunin, a plant derivative that, despite a long history of medicinal use, is not well understood molecularly. (Science Daily)
Paramecia Adapt Their Swimming To Changing Gravitational Force Sep 21, 2006
Methods for studying a biological response to altered gravity had been few and troublesome in Earth-based laboratories ... This new method will allow researchers to subject small biological systems to gravitational effects similar to those encountered in space, allowing less expensive and more complex experiments on the biological response to altered gravity. (Science Daily)
Thoughts turn to motion for patients with implant Jul 13, 2006
That was cool -- that was probably one of the highlights," said Nagle, 26, who was injured in a knife attack in 2001 .Nagle is one of four people who have received an experimental brain implant that turned their thoughts of motion into actual movements.The research into their experiences has been reported before in the popular media, but yesterday, it became the cover story in Nature, its first appearance in the kind of peer-reviewed journal that provides scientific legitimacy. The report... (Boston Globe)
Lorus announces presentation of data from four clinical trials with three different drugs at the 2006 American Society of Clinical Oncology (ASCO) Meeting Jun 1, 2006
More about the Presentations at ASCO Pancreatic Cancer: Data will be presented from the recently completed phase III clinical trial of Virulizin(R), a biological response modifier that has been shown to have immune stimulatory and anticancer activity in animal models of several human cancers. Early clinical trials indicated that Virulizin(R) appeared to be an effective treatment for pancreatic cancer. (Canada Newswire)
New Nano-canary In The Nanotoxicology Coalmine: The Body Itself Feb 23, 2006
These include the potential to detect biologically active nanoparticles without any prior knowledge of cell signaling pathways affected by them or need of a contrast agent to detect the biological response ... "We believe this report outlines the first use of FTIR spectroscopy to examine the biological response of living cells to nanoparticles, and expect this technology will enable us to identify chemical changes associated with the biological response," said Weber. (Science Daily)
MIV Therapeutics Hires Noted Pharmacology Scientist Dr. Vlad Budzynski to Direct Multiplatform Drug Delivery Program; Veteran Researcher and University Professor Brings Expertise in Drug Development and Advanced Biomedical Solutions Feb 10, 2006
Dr. Budzynski has had an accomplished and multifaceted scientific career in the research and discovery of biological response modifiers, vaccines, monoclonals and cytotoxic drugs. He received his Ph. (CBS MarketWatch - Press Releases)
Two NIH initiatives launch intensive efforts to find roots of common diseases Feb 9, 2006
Therefore, GEI will also invest in innovative new technologies to measure environmental toxins, dietary intake and physical activity, and to determine an individual's biological response to those influences, using new tools of genomics, proteomics and metabolomics. "Differences in our genetic makeup certainly influence our risks of developing various illnesses," said David A. Schwartz, M.D., Director of the National Institute of Environmental Health Sciences, also part of NIH, and co-chairman of... (EurekAlert! -- Business News)
