Teen Survives 5 Heart Attacks, Is in Race Against Time May 29, 2008
Chaiban, 17, has Barth Syndrome ... A conference this July in Florida with other Barth Syndrome sufferers will offer hope for Chaiban and his family, who run a car-repair business in Coburg, Australia. (Fox News)
Little boy spirit Nov 22, 2007
Benjamin Holly, left, of Monahans, was the first boy ever diagnosed prenatally with Barth syndrome ... Hes a Barth Syndrome boy, afflicted with a rare genetic disease that affects his hearts strength and saps his muscles of energy ... With six healthy siblings, including one boy, Josh, Keli and Greg Holly were unaware that Keli, who carries the recessive gene, had a 50 percent chance of passing Barth Syndrome on to her boys. (Odessa American, TX)
Abnormal fat metabolism underlies heart problems in diabetic patients Aug 11, 2007
Interestingly, a rare genetic disorder Barth syndrome held a key to identifying cardiolipin decrease in diabetic hearts. Children born with Barth syndrome have weak hearts and often die young from heart failure ... The connection between cardiolipin and heart disease in Barth syndrome led the Washington University researchers to wonder if cardiolipin was also affected in diabetic hearts. (EurekAlert!)
UCLA chemists' study of protein may provide insights into heart disease and cancer Aug 11, 2006
Carla Koehler, a UCLA associate professor of chemistry and biochemistry, and Steven Claypool, a UCLA postdoctoral scholar in chemistry and biochemistry, report in the current issue of the Journal of Cell Biology about the "tafazzin" protein, which plays a key role in Barth syndrome ... Mutations in the tafazzin gene lead to Barth syndrome, said Koehler, who noted that tafazzin is named after an Italian cartoon character ... Barth syndrome appears to be a disease of the mitochondria, the tiny... (EurekAlert!)
