Slaters set to put on a show Nov 5, 2009
"In three years, they've caught more than 50 probable melanomas (the most severe), and hundreds of basal cell and squamous (skin cancers)," said Drew Filliben, one of the World Skin Cancer Foundation's co-founders. "It's just the awareness of seeing their surfing heroes promote this kind of lifestyle that makes it all worthwhile.". (Florida Today)
Curis shrinks 3Q loss as partnership revenue rises Oct 30, 2009
Curis is conducting an early-stage trial of potential cancer drug called CUDC-101, and has a partnership with Roche's Genentech unit on GDC-0449, which is being tested against advanced basal cell carcinoma and ovarian cancer. It also announced a partnership with Debiopharm during the third quarter, and Debiopharm is now covering all the costs of developing a cancer treatment called CUDC-305. (Yahoo News -- Pharmaceutical Industry News)
Could my new 'freckle' be another basal cell carcinoma? Oct 29, 2009
Could my new 'freckle' be another basal cell carcinoma ... Could my new 'freckle' be another basal cell carcinoma ... I have basal cell carcinoma. (CNN -- Health)
Low-Fat Diet May Reduce Second Skin Cancer Risk Oct 27, 2009
Two forms of non-melanoma skin cancer -- basal cell carcinoma and squamous cell carcinoma -- account for the large majority of skin cancers and are easily treatable when caught early ... During follow up lasting 11 years, 267 of the study participants developed 664 basal cell skin tumors ... The researchers found no significant association between the amount of fat consumed daily and the overall risk of basal cell or squamous cell cancers, after allowing for a variety of factors potentially... (Newsmax)
HEALTH SEC SICK? Oct 22, 2009
Sebelius had a basal cell carcinoma removed from her forehead on Tuesday during a successful standard outpatient procedure, according to HHS spokeswoman Jenny Backus ... Basal cell carcinoma is a slow-growing form of skin cancer that can appear as a bump or growth ... She would not look like this from a basal cell removal from her forehead unless a 1st grader did the cutting. (The Drudge Report)
Regulating The Regulators: New Therapeutic Approach Against Cancer Sep 22, 2009
For example, a Toll-like receptor (TLR) agonist, called imiquimod, which activates dendritic cells, is in clinical use as a topical application for basal cell carcinoma. In addition, a number of TLR agonists have been evaluated in clinical trials as an adjuvant for cancer vaccines. (Science Daily)
How Stem Cells Make Skin Sep 14, 2009
This also happens at the initial stages of basal cell carcinomas. In skin where C/EBP-beta is present but has lost its capacity to interact with E2F, a molecule that regulates the cell cycle (right), skin cells start differentiating abnormally, before they have properly exited the stem cell "program" (yellow/orange). (Science Daily)
New Type Of Adult Stem Cells Found In Prostate May Be Involved In Cancer Development Sep 11, 2009
But the only stem cells previously described in the prostate are basal cells, which have been considered to form a "support" layer for the luminal cells that make prostate secretions. However, since prostate cancers are filled exclusively with cells that have features of luminal cells, it has been unclear how cancer might arise from basal cells. (Science Daily)
Prostate cancer-causing stem cell identified Sep 10, 2009
Shen said researchers had believed that tumors arise from a different layer of cells in the prostate, called basal cells. "Previous research suggested that prostate cancer originates from basal stem cells, and that during cancer formation these cells differentiate into luminal cells," Shen said in a statement. (MSNBC -- Health)
New Compound Shrinks Skin Cancers Sep 4, 2009
Study found more than half of advanced basal cell carcinomas responded to treatment ... WEDNESDAY, Sept. 2 (HealthDay News) -- An experimental cancer drug that switches off the so-called "Hedgehog" pathway beat back tumors in more than half of patients with advanced basal cell carcinoma, a type of skin cancer ... Some 1 million Americans get basal cell carcinoma each year. (MEDLINEplus)
Novel Anti-cancer Drug Yields Positive Response In People With Advanced Skin And Brain Cancer Sep 4, 2009
3, 2009) The Hedgehog signaling pathway is involved in a preliminary study and case report describing positive responses to an experimental anticancer drug in a majority of people with advanced or metastatic basal cell skin cancers ... In the Phase I clinical study, 33 patients with advanced basal cell skin cancer were treated with GDC-0449, an oral drug made by Genentech ... Basal cell skin cancers are the most common type of cancer in adults and are often cured with surgery. (Science Daily)
Pill shows promise in hard-to-treat cancers Sep 3, 2009
In an early-stage study, the drug being developed in partnership with Curis Inc, shrank tumors in half of a small group of patients with basal cell skin cancer that had spread to their organs ... Dr. Charles Rudin of the Johns Hopkins Kimmel Cancer Center, who worked on the studies, said the Hedgehog signaling pathway appears to play a role in lots of cancers, but it seems to be particularly important in medulloblastoma and basal cell carcinoma, the most common type of skin cancer ... In most... (MSNBC -- Health)
Potential Skin Cancer Breakthrough Tested at Scottsdale Healthcare Published Today in New England Journal of Medicine Sep 3, 2009
Hedgehog trial results suggest antitumor activity in basal cell skin cancer ... Sept. 2 /PRNewswire-USNewswire/ -- A study published today in the New England Journal of Medicine reports a potential new investigational therapy for advanced and metastatic basal cell skin cancer tested at the Virginia G. Piper Cancer Center at Scottsdale Healthcare and other sites appears to demonstrate tumor shrinkage and limited side effects in patients ... These findings are significant because there is no... (PR Newswire)
Experimental cancer drug shows promise Sep 3, 2009
It was used to test patients with advanced basal cell carcinoma, a rare type of skin cancer. Basal cell skin cancer is the most common type of cancer and is easily treated if detected in time ... "We have something here that has very few side effects and substantial activity against advanced basal cell," said Von Hoff, who serves as physician-in-chief at the Translational Genomics Research Institute. (AZCentral -- Business)
Some brain tumors may be mediated by tiny filament on cells Aug 24, 2009
The study, conducted in mice and in human brain tissue of medulloblastomas, coincides with a study by another team of UCSF scientists showing that the structure, known as primary cilium, also may play a role in basal cell carcinoma, the most common form of skin cancer ... Aberrant Hedgehog signaling is well known to lead to human cancers, including basal cell carcinoma and medulloblastoma. (EurekAlert!)
Some skin cancer may be mediated by primary cilia activity Aug 24, 2009
The new study focused on basal cell carcinoma, the most common cancer in the United States ... If the basal cell carcinoma finding is confirmed in people, the discovery raises the possibility of new cancer treatment strategies, said Jeremy Reiter, MD, PhD, senior author of that paper ... When mutated, they can trigger basal cell carcinoma and other cancers. (EurekAlert!)
Anti-oncogenic and pro-differentiation effects of clorgyline, a monoamine oxidase A inhibitor, on high grade prostate cancer cells Aug 20, 2009
Monoamine oxidase A (MAO-A), a mitochondrial enzyme that degrades monoamines including neurotransmitters, is highly expressed in basal cells of the normal human prostatic epithelium and in poorly differentiated (Gleason grades 4 and 5), aggressive prostate cancer (PCa). Clorgyline, an MAO-A inhibitor, induces secretory differentiation of normal prostate cells. (BioMed Central)
How to Tell Liver Spots from Moles and Cancer Aug 7, 2009
Search Type Choose a search type from the items below. Most Viewed - Health. (Yahoo News -- Technology)
JA workshop explores skin cancer causes, prevention Aug 5, 2009
Hanson talked about the three main types of skin cancers: basal cell carcinoma, melanoma and squamous cell carcinoma, which is the most deadly. He stressed that if the appearance of a mole or freckle seems to change in symmetry, border, color or diameter, it's time to have it looked at. (Brookhaven Daily Leader, MS)
Duke scientists create airway spheres to study lung diseases Jul 29, 2009
"Now that we have this 3-D model and information about the gene expression 'signature' of basal cells, we are in a strong position to see what happens when lung-cell behavior goes awry," Hogan said. "We might, for example, be able to activate an oncogene (a cancer-causing gene) or other factors to see how lung cancer might develop in the airways. Amazingly, almost nothing is known about lung basal cells, which are so important to health and make up nearly a third of the cells in the human... (EurekAlert!)
Ask a Dermatologist: Real advice about sun exposure, protection (1) Jul 20, 2009
5 times more likely to develop basal cell carcinoma, says Hill ... Fortunately, the two most common kinds basal cell carcinoma and squamous cell carcinoma are usually easily treated with little chance of spreading, says Hill. (Bartlesville Examiner-Enterprise, OK)
The Dark Side of the Sun Jul 15, 2009
Basal cell and squamous cell carcinomas are the two most common forms of skin cancer, but they are both easily treated if found early, said Dr. Reinberg. Melanoma also is treatable if caught early, he stressed. (Missourian Publishing, MO)
Mice With Skin Condition Help Scientists Understand Tumor Growth Jul 9, 2009
About 10 percent of these tumors spontaneously progressed to basal cell carcinoma, the most common type of skin cancer in people. Importantly, further analysis showed that skin tumors had originated from both mutant and normal skin cells. (Science Daily)
Tips will help you stay safe this summer Jul 9, 2009
Problem: Sunburns can present a risk for skin cancers, such as basal cell carcinoma and melanoma in the future. Excessive ultraviolet exposure also can damage eyes the cornea, the lens and even the retina. (Winona Daily News, MN)
Summer hazards Jul 6, 2009
One in five Americans will get skin cancer, and most of these will be basal cell carcinoma. This type of cancer is rarely fatal, but it can be disfiguring. (Boston Globe)
New Skin Cancer Patch: Possible Alternative To Surgery Jun 19, 2009
ScienceDaily (June 18, 2009) A new study shows that a radioactive skin patch can safely and successfully treat basal cell carcinoma, one of the most common types of skin cancers, according to researchers at the SNM's 56th Annual Meeting ... "While basal cell carcinoma is rarely fatal, it can be a painful and disfiguring disease," said Priyanka Gupta, a nuclear medicine technologist in the Department of Nuclear Medicine at All India Institute of Medical Sciences, New Delhi, and lead author of the... (Science Daily)
Sleuths Follow Lung Stem Cells For Generations To Shed Light On Healing Jun 6, 2009
From other experiments, Hogan and her colleagues think these replenishing cells are basal cells. "In the wider trachea, there is a population of basal cells that are more like classical stem cells in being undifferentiated," Hogan said. (Science Daily)
Skin lesion leads to new cancer forms Jun 4, 2009
And one-third of patients who ended up with basal cell carcinoma, the most common form of skin cancer could also trace their cancers to actinic keratoses. Scientists had previously been able to connect squamous-cell carcinomas to the lesions, but not basal cell. (India Times, India)
The Dangers of Tanning Jun 2, 2009
Basal cell carcinoma, the most common form in Caucasians, Hispanics, Chinese, and Japanese populations (Gloster & Neal, 2006). Squamous cell carcinoma, the most common form among African Americans and Asian Indians (Gloster & Neal, 2006). (Suite101.com)
Promote Vitamin D Testing for Public Joint Canadian Tanning Association urges Canadian Cancer Society Jun 1, 2009
"There is no direct data about the effect of sunscreens on melanoma and basal cell cancers," according to the U.S. Center for Disease Control. The World Health Organization has issued a similar statement. (Canada Newswire)
Skin cancer is colorblind -- no 'free pass' May 31, 2009
She had basal cell carcinoma, the most common skin cancer ... The American Cancer Society estimates that in 2009 there will be more than 1 million unreported cases of basal cell and squamous cell skin cancer -- most of them curable -- and that more than 68,000 cases of melanoma will be diagnosed. (CNN -- Health)
Yumans have greater risk for skin cancer May 25, 2009
" According to the AAD, Actinic keratoses or solar keratoses are considered the earliest stage in the development of skin cancer. They are small, scaly spots most commonly found on the face, ears, neck, lower arms, and back of the hands in individuals who have had significant sun exposure. The AAD said there are three types of skin cancer. Basal cell carcinoma is the most common type and appears frequently on the head, neck, and hands as a small, fleshy bump, nodule, or red patch. Other parts of... (Yuma Daily Sun, AZ)
Impact Of The Sun While Sailboardin... May 23, 2009
Basal cell carcinoma is the most common. Squamous cell carcinoma is an ulcer or lump. (Suite101.com)
Why the thumb of the right hand is on the left hand side May 23, 2009
"This is evidence for the notion that cells use various molecular mechanisms for interpreting different Hedgehog concentrations." This fact may also be of importance for the diagnosis and treatment of certain cancers (basal cell carcinoma), where the constant up-regulation of the Hedgehog signal is responsible for uncontrolled cell growth. Aanstad published the findings together with her colleagues from the University of California, San Francisco in the journal Current Biology. (EurekAlert!)
Flip-Flops and Baseball Caps Raise Cancer Risk May 22, 2009
Most skin cancers are classified as nonmelanoma, usually occurring in either basal cells or squamous cells. These cells are located at the base of the outer layer of the skin or cover the internal and external surfaces of the body. (Newsmax)
Annual Melanoma walk set for May 30 May 22, 2009
The American Cancer Society (ACS) estimates that, during 2009, about 1 million new cases of basal cell or squamous cell carcinoma and about 68,720 new cases of malignant melanoma will be diagnosed. Skin cancer will likely claim the lives of approximately 11,590 Americans in 2009. (McKinney Courier-Gazette, TX)
Young pay unexpected price for 'healthy' tan May 18, 2009
The three main types of skin cancer are basal cell, squamous cell and melanoma. Basal cell and squamous cell are the two most common forms of skin cancer, but are easily treated if detected early. (Park Hills Daily Journal, MO)
5 things you should know about ... skin cancer May 13, 2009
Research shows that skin screenings can lead to early detection, and both basal cell and squamous cell carcinomas have a 95 percent cure rate when detected and treated early. IF YOU GO. (La Crosse Tribune, WI)
Health Matters: Protect your skin, screen for cancer May 12, 2009
Most are either basal cell or squamous cell carcinomas which seldom become life threatening ... The American Cancer Society estimates that more than 1 million cases of highly curable basal cell or squamous cell cancers occur annually in Americans each year, making it the most common form of the disease. (Needham Tab, MA)
Lewisville lodge hosting blood drive Saturday May 8, 2009
Cancer: OK to donate after curative treatment for basal cell skin cancer and squamous cell skin cancer. For most solid tumors, including those because of breast cancer, it is OK to give five years after completion of all treatment. (McKinney Courier-Gazette, TX)
How to avoid skin cancer May 5, 2009
There are three types: basal cell and squamous cell carcinomas and melanoma ... At 41, she's had all three types of the condition: basal cell carcinoma, squamous cell carcinoma and melanoma. (CNN -- Health)
Dr. Ken Beer: What You Need to Know About Skin Cancer Mar 17, 2009
Sometimes you can find small areas that bleed or dont heal (usually basal cell carcinomas) ... Mohs is usually reserved for basal cell or squamous cell carcinomas on the face or hands but in some instances may be used on other types of skin cancers including those that are large (greater than 2 centimeters), invasive, that were not cured with previous surgeries or that are recurrent. (Newsmax)
Control your DNA destiny Mar 13, 2009
And 68 percent of patients with basal cell carcinoma, the most prevalent form of skin cancer, have a single gene mutation in common, report scientists at Yale University in New Haven, Connecticut. Override your DNA: Genes play a role in 40 percent of melanomas, which means the majority of cases are preventable. (MSNBC -- Health)
More tanningsalons than Starbucks? Mar 10, 2009
Unfortunately, tanning more often means upping your risk of melanoma and non-melanoma skin cancer such as squamous cell carcinoma and basal cell carcinoma. According to the American Academy of Dermatology, studies have also shown that excessive exposure to UV radiation during indoor tanning leads to skin aging, immune suppression and eye damage, including cataracts and ocular melanoma. (MSNBC -- Health)
Treatment of Skin Damaged by the Su... Feb 22, 2009
Skin damage can take the form of thick scaly patches called keratoses, squamous cell carcinoma, basal cell carcinoma, and melanomas. of this article dealt with the use of sunscreens and their detrimental effects on the body, the second part covers treatments and prevention of skin cancer. (Suite101.com)
Blocking Protein Leads To Fewer, Smaller Skin Cancer Tumors Feb 20, 2009
The two most common types are basal cell carcinoma, which forms in small cells in the base of the outer layer of skin, and squamous cell carcinoma, which forms in cells that compose the surface of the skin ... Satoskar and colleagues plan to examine biopsies of patients who have been diagnosed with squamous cell or basal cell carcinoma to see if these patients have a polymorphism on the MIF gene that would suggest a genetic predisposition toward the cancer. (Science Daily)
