SurfWax News Index  |  Track News  |  Save/Exchange Information |  About Us

    News and Articles on Base pair



    Simplest Animal's Genome Reveals Complexity  Aug 23, 2008
    The analysis of the 98 million base pair genome of Trichoplax (literally "hairy-plate") illuminates its ancestral relationship to other animals. Trichoplax is the sole member of the placozoan ("tablet," or "flat" animal) phylum, whose relationship to other animals, such as bilaterians (humans, flies, worms, snails, et al) and cnidarians (jellyfish, sea anemones, corals, et al), and sponges is contentious. (Science Daily)

    Gene Variant May Decide Who Smokes and for How Long  Aug 9, 2008
    The regular smokers were far more likely than never-smokers to have less common form of the CHRNA5 gene in which just one base pair in the gene sequence is different from the more common form of the gene. Smokers were also eight times more likely than never-smokers to have got a pleasurable buzz when they tried their first cigarette. (Health-Finder)

    Blocking HIV Multiplication: Structure Elucidation Of 'Kissing Complex'  Aug 8, 2008
    To understand the role of this base pair and to permit synthesis of RNAs capable of binding more effectively to the viral regulator sequence, it was necessary to precisely elucidate how this binding takes place and define the essential parameters for its stabilization. By developing innovative NMR tools for the structural study of RNAs in solution, IBS and Ottawa University scientists determined with a very high precision the structure of the complex formed by the two RNAs in solution and... (Science Daily)

    New research on mutation in yeast can enhance understanding of human diseases  Jun 20, 2008
    While C. elegans mutations were largely the result of inserting or deleting base pairs of DNA, yeast's patterns of mutation were characterized by changing one base pair for another ... He adds that the consequences of inserting and deleting base pairs can be much more dramatic than substituting one base pair for another ... This way, the yeast accumulate mutations that might otherwise make them "bad yeast" the weak survive and look for them across the entire 10 million base pair genome. (EurekAlert!)

    Is ADHD An Advantage For Nomadic Tribesmen?  Jun 11, 2008
    A study led by Dan Eisenberg, an anthropology graduate student from Northwestern University in the US, analyzed the correlates of body mass index (BMI) and height with two genetic polymorphisms in dopamine receptor genes, in particular the 48 base pair (bp) repeat polymorphism in the dopamine receptor D4 (DRD4) gene. The DRD4 gene codes for a receptor for dopamine, one of the chemical messengers used in the brain. (Science Daily)

    ASU researcher working to strengthen DNA  Jun 10, 2008
    Serving Arizona State University Online Since 1995. Current Issue: Monday, June 09, 2008. (Web Devil, AZ)

    Eight New Human Genome Projects Offer Large-scale Picture Of Genetic Difference  May 2, 2008
    The researchers created what's called a clone map, taking multiple copies of each of the eight genomes and breaking them into numerous segments of about 40,000 base pairs, which they then fit back together based on the human reference genome. They searched for structural differences that ranged in size from a few thousand to a few million base pairs ... Base pairs are one of the basic units of information on the human genome. (Science Daily)

    Gene Variant Increases Risk Of Asthma  Apr 15, 2008
    That variation changes one DNA base pair, out of the 3 billion in the human genome, at a location in the CHI3L1gene known as -131C/G. Those with asthma were more likely to have a cytosine (C), rather than guanine (G) at this location. Those inheriting two copies of a C at -131 had higher YKL-40 levels and an asthma prevalence of 0. (Science Daily)

    Discussion to focus on women in medical field  Apr 8, 2008
    Five women physicians who are alumnae of Jackson Public Schools and Base Pair the research mentorship program between JPS and the University of Mississippi Medical Center will share their perspectives today on Recruiting the Next Generation: Women in Biomedicine ... JPS students enrolled in Base Pair and Student Oriented Academic Research (SOAR) programs have organized the panel as their spring 2008 community science forum ... Panelists are: Dr. Ayanna Jenkins, Jackson-Hinds Comprehensive... (The Clarion-Ledger)

    UCLA researchers examine human embryonic stem cell genome  Mar 28, 2008
    Forms of variation include single DNA base pair alterations, duplications or deletions of genes or sets of genes, and translocations, a chromosomal rearrangement in which a segment of genetic material from one chromosome becomes heritably linked to another chromosome. These changes can be benign, but they can also promote diseases such as certain cancers, or confer increased risk to other diseases, such as HIV infection or certain types of kidney ailments. (EurekAlert!)

    Of the Pills We Take  Mar 23, 2008
    Dr. Bustamante compared 10,000 genes shared by 15 African-Americans and 20 European-Americans and found nearly 40,000 individual differences in which a gene's smallest structural unit -- a single DNA base pair -- had been altered. Half of them had no measurable effect. (Wall Street Journal)

    Bogue Chitto eyes cutting-edge research class  Mar 22, 2008
    The method of introduction between student and researcher began as a program called Base Pair ... "It is a very close association that mimics the binding of base pairs fundamental to the structure of DNA." ... The catalyst for the Base Pair system is proximity. (Brookhaven Daily Leader, MS)

    Education briefs  Mar 2, 2008
    Applications are being accepted for teacher professional development workshops, a component of the Base Pair/SOAR program funded by the Howard Hughes Medical Institute ... For additional information, call (601) 815-1269, send an e-mail to Donna C. Sullivan at or Gail Howell at )or visit the Base Pair Web site at http:// basepair. (The Clarion-Ledger)

    A little less than perfect  Feb 28, 2008
    It's nothing extraordinary -- just one or two base pairs, if you are biologically inclined. But base pair inversions are easier to explain, and no one's surprised when they happen, time to time. (The Cavalier Daily, VA)

    New Way To Store Information Via DNA Discovered  Feb 26, 2008
    Given the size of the DNA fragments (one base pair of DNA is 0. 33 nanometers), one could store a large amount of information in a very small space. (Science Daily)

    Ancient Impact Seen In Modern European Diversity  Feb 22, 2008
    The researchers focused on single nucleotide polymorphisms (SNPs), where a single DNA base pair (the smallest structural unit) in a gene's sequence had been altered. Genetic variations were classified as to whether a SNP was found in one or both populations. (Science Daily)

    Please sequence my eel  Feb 9, 2008
    The only way to get at those genes is to sequence every last base pair of the genome, says James Albert, one of the papers authors and a fish biologist at the University of Louisiana at Lafayette. Many applications. (Nature News Service)

    Washington University increases fleet of Roche Genome Sequencer FLX Systems  Feb 8, 2008
    The Centers system improvements will include an increase in sequence read length beyond 400 base pairs and a dramatic increase in the number of sequencing reads per instrument run ... With the longer 400 base pair read lengths, we can start to assemble the genomes using a de novo approach, eliminating the need to remap the sequences to a reference genome that can lead to errors. (EurekAlert! -- Business News)

    DNA does the work: Building new gold crystals  Feb 1, 2008
    The idea takes advantage of the molecular biology of DNA, in which one strand of DNA forms a bond with a complementary strand to make what is called a base pair. Mirkin and colleagues simply design the specific genetic code using the four building blocks of DNA -- adenine, guanine, cytosine and thymine or A, G, C and T -- and attach the gold particles to those strands. (Reuters UK)

    Carolyn Abraham on creating artificial life  Jan 29, 2008
    "The feat marks a historic and controversial milestone in the fledgling field known as synthetic biology. A team of 17 researchers at the J. Craig Venter Institute (JCVI) has created the largest man-made DNA structure by synthesizing and assembling the 582,970 base pair genome of a bacterium, Mycoplasma genitalium JCVI-1.0. (Credit: www.jcvi.org) Related Articles Recent Internet Links "It uses chunks of synthetic DNA like Lego blocks, with an aim to create life forms that can be genetically... (Globe and Mail)

    Lab-made genome gives life to ethics debate  Jan 26, 2008
    Dr. Venter noted that having commercial labs synthesize the pieces cost less than a dollar for each base pair of nucleotides. Robert Holt, a scientist at the Genome Science Centre of the BC Cancer Agency, and a former collaborator with the Venter group, called the report an important technical accomplishment because the size of the DNA molecule constructed dwarfs previous efforts. (Globe and Mail)

    Scientists create man-made DNA map  Jan 26, 2008
    The researchers at the J Craig Venter Institute in Rockville created the artificial genome code - the chemical blueprint of life - by synthesising and assembling 582,970 base pair genome of bacterium Mycoplasma genitalium JCVI-1. 0. (India Times, India -- Health/Science)

    Longest Piece of Synthetic DNA Yet  Jan 25, 2008
    "The 582,970 base pair M. genitalium bacterial genome is the largest chemically defined structure synthesized in the lab," lead author Daniel Gibson told ScientificAmerican ... (Base pairs are complementary linked nucleotide bases, such as adenine thymine. (Scientific American)

    Scientists Create First Synthetic Bacterial Genome -- Largest Chemically Defined Structure Synthesized In The Lab  Jan 25, 2008
    24, 2008) A team of 17 researchers at the J. Craig Venter Institute (JCVI) has created the largest man-made DNA structure by synthesizing and assembling the 582,970 base pair genome of a bacterium, Mycoplasma genitalium JCVI-1 ... Prior to today s publication the largest synthesized DNA contained only 32,000 base pairs ... Thus, building a synthetic version of the genome of the bacteria M. genitalium genome that has more than 580,000 base pairs presented a formidable challenge. (Science Daily)

    NEJM editorial on significance and limitations of new lupus gene expression research  Jan 21, 2008
    The new research looks at how variations in a single DNA base pair, called single nucleotide polymorphisms (SNP), can be used to identify genetic variations among individuals that are associated with a diagnosis of lupus. In some cases, the SNPs call attention to important genes but have no apparent functional importance themselves. (EurekAlert!)

    Using Genes to Fight Pine Beetle  Jan 17, 2008
    " To find out, Aukema and fellow researchers at UNBC are collecting as many pine beetle samples as they can, looking at the insect in all its life stages -- from larvae to adult. The genes in each beetle sample are exposed to various chemicals, like pheromones or the chemicals in tree sap to determine what makes them "switch" on or off. "We're not sequencing every single base pair in the DNA," says Dezene Huber, a Canada Research Chair and associate professor at UNBC. "We're looking at these... (TheTyee.ca)

    Study puts doctors closer to genetic prostate-cancer test  Jan 17, 2008
    " The research team, from Johns Hopkins, Wake Forest University and the Karolinska Institute in Stockholm, drew blood from 2,893 prostate cancer patients and 1,781 matched "controls" who did not have the disease. Using DNA from blood cells, they sifted through variations in chemicals called nucleotides that pair up to form the DNA. These "single nucleotide polymorphisms," or SNPs (pronounced "snips"), occur when one chemical base pair is swapped for another, altering the information in the DNA... (Chicago Tribune)

    Scientists Discover Remarkable Editing System For Protein Production  Jan 4, 2008
    In addition to Beebe, Mock, and Schimmel, Eve Merriman was an author on the new Nature paper, entitled "Distinct domains of tRNA synthetase recognize the same base pair." All authors are from The Scripps Research Institute. The study was funded by the National Institutes of Health, the Skaggs Foundation, and the National Foundation for Cancer Research. (Science Daily)

    Are Humans Evolving Faster?  Dec 11, 2007
    Chromosomes are made of DNA, a twisting, ladder-like structure in which each rung is made of a "base pair" of amino acids, either G-C or A-T. Harpending says that about every 1,000 base pairs, there will be a difference between the two chromosomes. That is known as a SNP.. (Science Daily)

    Will nanobots help us to live forever?  Nov 22, 2007
    For example, the amount of genetic data collected has doubled every year since 1990, and the cost has come down from $10 per base pair to a fraction of a penny. As a result, technologies to literally reprogramme the "software" (ie the genes) that underlie human biology will be a thousand times more powerful than they are today in a decade, and a million times more powerful in two decades. (Guardian Unlimited -- Life)

    Localization of TFIIB binding regions using serial analysis of chromatin occupancy  Nov 13, 2007
    GSTs are 20-22 base pair fragments that are derived from TFIIB bound chromatin. TFIIB localized to both non-protein coding and protein-coding loci. (BioMed Central)

    Creationist draws on Bible to explain place in universe  Nov 11, 2007
    Eddie wrote on Nov 10, 2007 10:32 PM:" Phil, you're (not "your") quite mistaken. You need to educate yourself about basic biology. Mutations are changes to the base pair sequence of the genetic material of an organism. There are several types of mutations, and they can be advantageous, disadvantageous, or neutral towards an organism's survival. Speciation has been observed numerous times; fruit flies, African frogs, and especially the human-initiated creation of domestic sheep are prime... (La Crosse Tribune, WI)

    If mutations occur at random over the entire sequence of a species' genome, how can a complex organ such as an eye evolve? How can all the mutations that direct the development of that organ be concentrated in the right places?  Nov 1, 2007
    At more than six billion individuals, the human species is now so large that every single base pair of the three billion in the genome is mutated several times, somewhere in the population, every generation. Some of these mutations are so harmful that they're eliminated before their carriers are even born. (Scientific American)

    Masquerading for money: Tougaloo, Rust get ball rolling with scholarship event  Nov 1, 2007
    But science was her favorite subject, and good grades led to her three-year participation in Murrah's Base Pair program. The research mentorship program, funded by the Howard Hughes Medical Institute, annually matches 15 high school students with University of Mississippi Medical Center faculty members for in-depth science experiences. (The Clarion-Ledger)

    Were Neandertals the Original Redheaded Strangers?  Oct 27, 2007
    A 128 base pair fragment of MC1R was isolated from the Italian sample. (For reference, there are estimated to be 250,000,000 base pairs in the entire Neandertal genome. (Scientific American)

    SPECIAL REPORT: So similar, yet so different  Oct 18, 2007
    The new, more thorough version finds surprisingly high diversity in single nucleotide polymorphisms (SNPs) parts of the genome marked out by specific changes in a single DNA base pair. Bill Clinton: impressed by the revelatory power of DNA.R. EDMONDS/AP. (Nature News Service)

    IBM Opens New Doors to Quantum Computing  Sep 3, 2007
    Scientists from IBM have managed to partially confirm Feynmans theory and to give God his share of the glory and greatness for his inventiveness: our DNA uses 32 atoms to store information in one half of the chemical base pair that is the fundamental unit that makes up genetic information. With further work it may be possible to build structures consisting of small clusters of atoms, or even individual atoms, that could reliably store magnetic information. (eFluxMedia (press release))

    Scientists Find Clue To Mechanisms Of Gene Signaling And Regulation  Aug 24, 2007
    DNA methylation occurs across the animal genomes, almost always at the C base position of a CG dinucleotide (sequence of two base pairs) in the genetic sequence ... In the regions of the genome where genes are imprinted, called differentially methylated regions, they found a repeat pattern (periodicity) of 8 to 10 base pairs between two CG dinucleotides ... "We believe that this repeating pattern of 8 to 10 base pairs between CGs provides a signal for where the differential methylation should... (Science Daily)

    Genetic Phonetics Could Be The Trick To Sounding Out DNA's Meaning  Aug 22, 2007
    Most modern attempts to decipher how portions of genetic code are translated into physical characteristics are akin to a first-grader trying to sound out a word letter by letter or, in this case, base pair by base pair. But University of Florida researchers have developed a computational method that s more like reading whole words at a time. (Science Daily)

    New genetic risk factors for multiple sclerosis found  Jul 30, 2007
    The three research teams analyzed thousands of patients of European descent, and found that a single base pair difference in the IL7R gene increased the risk of having MS by about 20. That risk is too low to make IL7R useful for a genetic test, cautions Margaret Pericak-Vance, a geneticist at the University of Miami in Florida, and an author on one of the studies. (Nature News Service)

    Mouse genome will help identify causes of environmental disease  Jul 30, 2007
    57 billion base pair of their standard reference strain. The data were then used to develop the haplotype map which contains 40,898 segments. (EurekAlert!)

    Hepatitis C helicase unwinds DNA in a spring-loaded, 3-step process  Jul 27, 2007
    What they found was that the DNA unwound in discrete jumps: Three nucleotide pairs (base pairs) had to be unhitched from one another before an unwinding event occurred ... You are loading the spring with small mechanical movements until finally you have accumulated enough tension on the DNA-protein complex to cause the rapid unwinding of three base pairs ... The researchers observed that three ATP molecules were consumed in each unwinding reaction, indicating that three hidden steps, each... (EurekAlert!)

    Semiconductor membrane mimics biological behavior of ion channels  Jul 13, 2007
    Since each base pair carries a different electrical charge, we could use the membrane as a p-n junction to detect the changing electrical signal. . (EurekAlert!)

    First Bacterial Genome Transplantation Changes One Species To Another  Jun 30, 2007
    Venter, Smith and Hutchison made the first significant strides in the development of a synthetic genome by their work in assembling the 5,386 base pair bacteriophage X174 (phi X). They did so using short, single strands of synthetically produced, commercially available DNA (known as oligonucleotides) and using an adaptation of polymerase chain reaction (PCR), known as polymerase cycle assembly (PCA), to build the phi X genome. (Science Daily)

    Going beyond X and Y  May 21, 2007
    In 1990, while at the University of Cambridge, Peter Goodfellow discovered SRY, a gene on the Y chromosome hailed as the "master switch." Just one base pair change in this sequence would produce a female instead of a male. And when researchers integrated SRY into a mouse that was otherwise chromosomally female, an XX fetus developed as a male. (Scientific American)

    Cataloging The Structural Variations In Human Genetics  May 11, 2007
    We know there is a genetic factor, but what is the role of single base pair changes versus structural changes. The project Eichler and his colleagues describe in their paper will help answer this question. (Science Daily)

    New Genetic Risk Factors For Type 2 Diabetes Identified  Apr 29, 2007
    This means researchers often need to take additional steps, such as sequencing every DNA base pair in that particular region of the genome, to identify the exact genetic variant that affects disease risk. In the latest work, researchers began by scanning the genomes of more than 2,300 Finnish people who took part in the Finland-United States Investigation Of NIDDM Genetics (FUSION) and Finrisk 2002 studies. (Science Daily)

    A cricket Gene Index: A genomic resource for studying neurobiology, speciation, and molecular evolution  Apr 26, 2007
    In addition, a set of unique 70 base pair oligomers that can be used for DNA microarrays was developed. All Gene Index information is posted at the DFCI Gene Indices web page. (BioMed Central)

    Two-step Process Filters Evolution Of Genes Of Human And Chimpanzee  Mar 7, 2007
    They focused their analysis on the simplest and most common mutations, those that alter just one letter, a single base pair, of DNA.. DNA uses a three-letter code to designate the 20 types of amino acids that are strung together in specific order to create a protein. (Science Daily)

    Your scent and your sex life  Feb 22, 2007
    "It was remarkably precise. ... A mouse can discriminate a mouse that differs by one DNA base pair mutation in one MHC gene," says Monell director Gary Beauchamp. Other studies showed that when it came to mating, opposites attracted -- in both mice and men. (Seacoast New Hampshire)

    New Technique Assesses Effects Of Multiple Copies Of Genes On Disease Risk  Feb 1, 2007
    "The copy number variants we describe in this paper are numerous and fairly large they vary in length between two thousand and two million DNA base pairs," Graubert says ... -- The Human Genome Project (HGP) endeavoured to map the human genome down to the nucleotide (or base pair) level and to identify all the genes present in ... It is made up of 23 chromosome pairs with a total of about 3 billion DNA base pairs. (Science Daily)

    Where was the defense?  Dec 22, 2006
    Where was the defense. A fan's perspective on the Falcons. (Atlanta Journal-Constitution -- Sports)

    Genomic 'Firestorms' Underlie Aggressive Breast Cancer Progression  Dec 3, 2006
    It is made up of 23 chromosome pairs with a total of about 3 billion DNA base pairs ... -- The Human Genome Project (HGP) endeavoured to map the human genome down to the nucleotide (or base pair) level and to identify all the genes present in. (Science Daily)

    Hi-Tech Initiative in Quest for Better Drugs  Dec 1, 2006
    Breast cancer sufferers could eventually benefit from high-tuned, tailor-made drug treatments that minimise side effects as a result of a joint initiative between computer scientists in Edinburgh and cellular biologists in Japan. Igor Goryanin, director of the Edinburgh Centre for Bioinformatics and Dr. Yoshiyuki Sakaki, head of Riken Genomic Research Centre. (Science Daily)

    Genetic Variation: We're More Different Than We Thought  Nov 25, 2006
    New research shows that at least 10 percent of genes in the human population can vary in the number of copies of DNA sequences they contain--a finding that alters current thinking that the DNA of any two humans is 99. 9 percent similar in content and identity. (Science Daily)

    DNA :: Human genome shows DNA differences - revised DNA map  Nov 24, 2006
    - identify all the approximately 20000-25000 genes in human DNA,; determine the sequences of the 3 billion chemical base pairs that make up human DNA ... Example of dA-dT base pair as found within DNA double helix. (SpiritIndia)

    Neanderthal DNA sequenced  Nov 18, 2006
    More than one million base pairs of Neanderthal DNA have been sequenced, according to findings appearing this week in and that could begin to shed light on whether humans and Neanderthals interbred and when they diverged genetically ... The researchers investigated fragments of nuclear DNA roughly 100 to 200 base pairs long, which were extracted from a 38,000-year-old Neanderthal bone from Vindija Cave in Croatia ... In their Nature paper, at the Max Planck Institute for Evolutionary... (The Scientist)

    Neanderthal Genome Sequencing Yields Surprising Results And Opens A New Door To Future Studies  Nov 17, 2006
    In a paper published in the November 17, 2006 issue of the journal Science, a team of researchers led by Edward Rubin, director of both JGI and Berkeley Lab s Genomics Division, reports the development of a Neanderthal metagenomic library, which they used to characterize more than 65,000 DNA base pairs of Neanderthal origin ... Said Rubin, We predict that in the near future anthropologists will be able to develop hypotheses about our extinct ancestors through the scanning of billions of base... (Science Daily)

    What happened to the Neanderthals? Check their DNA.  Nov 17, 2006
    The sequences the two teams have produced cover 65,000 to 1 million base pairs. Each base pair is built from four basic chemicals that make up an organism's genetic "code." Each base pair forms a "rung" on the DNA molecule's ladder ... By comparison, the human genome, and presumably the Neanderthal's, consists of some 3 billion base pairs. (Christian Science Monitor)

    Decoded Sea Urchin Genome Shows Surprising Relationship To Humans  Nov 11, 2006
    The Sea Urchin Genome Sequencing Project (SUGSP) Consortium, led by the Human Genome Sequencing Center at Baylor College of Medicine (BCM-HGSC) in Houston, announced today the decoding and analysis of the genome sequence of the sea urchin, Strongylocentrotus purpuratus. A group of adult purple sea urchins spawns in a kelp bed off the California coast. (Science Daily)

    Phoenix Rising: Scientists Resuscitate A 5 Million-year-old Retrovirus  Nov 1, 2006
    "Retroviruses, whose genomes consist of RNA, can create DNA "copies" of the RNA genomes and incorporate them into the genomes of their hosts. Phoenix belongs to a sub-category of retroviruses--known as HERVs (human endogenous retroviruses)--which inserted copies into the human germline millions of years ago. These copies were subsequently passed on from generation to generation. Remnants of HERVs now comprise nearly 8% of the human genome, but most were rendered inactive long ago by... (Science Daily)

    Honey Bee Genome: Social Insect Creates Buzz For Agricultural, Biomedical Research  Oct 27, 2006
    D., co-director of the Human Genome Sequencing Center at Baylor College of Medicine (BCM-HGSC) in Houston, describes the approximately 260 million DNA base pair genome of the honey bee (Apis mellifera) ... Although only 9 percent the size of the 3 billion base pairs in the human genome, the honey bee contains nearly half as many genes as the human genome, more than 10,000 in the bee compared to around 20,000 genes in the human. (Science Daily)

    Steelers wheelin,' Falcons reelin'  Oct 21, 2006
    1 billion base pairs that make up the 30,000 genes. People differ in 1 out of every 1,000 of these base pairs ... Each change in a base pair can alter a gene. (Atlanta Journal-Constitution -- Sports)

    A Ruler Of Gold And DNA: New Tool Could Expedite Scientists' Push To Learn How Genetic Information Is Processed  Oct 16, 2006
    For example, if the gold particle s spidery DNA strands, which are 54 base pairs long, are shortened for whatever reason, then the gold-DNA particle s scattering wavelengths also shift and this shift can be easily detected using spectroscopy. This method is so sensitive that scientists can use it to detect whether a DNA strand has been shortened by as little as one base pair in length, which opens the door for mapping the exact location of protein-DNA interactions ... As usual, they attached to... (Science Daily)

    Focusing in on Cancers Complexity  Sep 8, 2006
    For example, 59 percent of the colorectal cancer mutations went from a C:G base pair to an T:A pair, whereas this was the case for only 35 percent of the breast cancer mutations. These differences may be due to different kinds of carcinogens, different types of repair mechanisms, or different exposures to endogenous mutagens, said Vogelstein. (Howard Hughes Medical Institute)

    Unprecedented Genetic Study May Help Identify People Most At Risk For Alcoholism  Aug 26, 2006
    The normal human genome consists of about 3 billion base pairs of DNA in each set of chromosomes from one parent ... -- The Human Genome Project (HGP) endeavoured to map the human genome down to the nucleotide (or base pair) level and to identify all the genes present in. (Science Daily)

    Mitochondrial DNA sequencing tool updated  Aug 26, 2006
    The genome consisted of 16,568 base pair, or units, of DNA and encoded 37 contiguous genes. But because of the balky sequencing tools of the day and their high cost, much of the subsequent research progressed slowly or stalled. (EurekAlert!)

    Emory Scientists Develop New Map Of Genetic Variation In Human Genome  Aug 12, 2006
    The human genome sequence in our DNA contains three billion base pairs of four chemical building blocks--adenine, thymine, cytosine, and guanine (A, T, C, G), strung together in different combinations in long chains within 23 pairs of chromosomes ... Dr. Devine says INDELs can be grouped into five major categories, depending on their effect on the genome: (1) insertions or deletions of single base pairs; (2) expansions by only one base pair (monomeric base pair expansions); (3) multi-base pair... (Science Daily)

    Gene Variant Increases Risk Of Type 2 Diabetes; But Healthy Lifestyle Changes Reduce Genetic Risk  Jul 24, 2006
    It is a single nucleotide polymorphism (SNP), or single base pair change, in the region of a gene that codes for a transcription factor a protein that acts like a master switch regulating the expression of other genes. In their DNA analysis, the researchers found one copy of the risk variant in 40 percent of DPP participants, and two copies in 10 percent. (Science Daily)

    Latest Sequencing Targets: Gibbon Genome Sequence To Be Added To Primate Tree  Jul 23, 2006
    The refined genome sequences will improve the accuracy of comparisons between mammalian genomes, one of the most effective ways to pinpoint the roughly 5 percent of the 3-billion base pair human genome that is most obviously functional ... -- The Human Genome Project (HGP) endeavoured to map the human genome down to the nucleotide (or base pair) level and to identify all the genes present in. (Science Daily)

    NHGRI announces latest sequencing targets  Jul 20, 2006
    The refined genome sequences will improve the accuracy of comparisons between mammalian genomes, one of the most effective ways to pinpoint the roughly 5 percent of the 3-billion base pair human genome that is most obviously functional. The seven mammals to be sequenced are: the nine-banded armadillo (Dasypus novemcinctus); domestic cat (Felis catus); guinea pig (Cavia porcellus); African savannah elephant (Loxodonta africana); tree shrew (Tupaia species); rabbit (Oryctolagus cuniculus); and a... (EurekAlert!)

    DNA overwinds when stretched  Jul 13, 2006
    The findings suggest DNA-binding proteins must induce changes in stretching or winding of DNA molecules in order to recognize binding sites that vary in length -- due, for instance, to base pair insertions or deletions, Bustamante said. "It would be interesting to test how DNA sequence affects the response to twist. This could be performed by comparing the single-molecule behavior of several DNA sequences," Lionnet added. (The Scientist)

    Reprogramming Biology  Jun 28, 2006
    Sequencing DNA has come down in price by half annually, from $10 per base pair in 1990 to under a penny today. The amount of genetic data we have sequenced has more than doubled every year. (Scientific American)

    Desalination Roadmap Seeks Technological Solutions To Increase Water Supply  Jun 11, 2006
    Posted: June 10, 2006. After one last meeting in San Antonio in April, Sandia National Laboratories researchers Pat Brady and Tom Hinkebein are putting the final touches on the updated Desalination and Water Purification Roadmap -- "Roadmap 2" -- that should result in more fresh water in parts of the world where potable water is scarce. (Science Daily)

    First Whole-genome Scan For Links To Obsessive Compulsive Disorder Reveals Evidence For Genetic Susceptibility  Jun 8, 2006
    Posted: June 7, 2006. A federally funded team of researchers including several from Johns Hopkins have identified six regions of the human genome that might play a role in susceptibility to obsessive compulsive disorder, or OCD. The study was published online June 6 in Molecular Psychiatry. (Science Daily)

    'Pinball protons' created by ultraviolet rays and other causes can lead to DNA damage  May 18, 2006
    The team at the University of Georgia studied how the removal of a proton from the Guanine-Cytosine (G-C) base pair is involved in creating lesions that can lead to replication errors ... The lesions are breaks in the hydrogen bonds, of which there are two in the G-C base pair ... The team discovered that the base pair minus its knocked-off proton can either break entirely or change its bonding angle--something that also causes improper replication. (EurekAlert!)

    Scientists Solve 30-year-old Mystery Of Mutant Mouse's Kidney Woes  May 2, 2006
    "To make sure this was the cause and not just a result of the problem, we analyzed the sequence of the aqp2 gene from the mutant mice, comparing it to the gene from other normal mice, and found a single base pair had changed.". The change swaps the amino acid serine for the amino acid leucine at a key position in the protein. (Science Daily)

    Gene Variant Associated With Obesity Risk Found With New Statistical Technique  Apr 17, 2006
    Posted: April 16, 2006. A pioneering statistical technique developed at the Harvard School of Public Health (HSPH) has helped identify a common gene variation associated with an increased risk for obesity. (Science Daily)

    Nanopore Method Could Revolutionize Genome Sequencing  Apr 11, 2006
    It should be possible to sequence strands of DNA that are tens of thousands of base pairs in length, possibly as long as an entire gene, in one pass through the nanopore ... -- The Human Genome Project (HGP) endeavoured to map the human genome down to the nucleotide (or base pair) level and to identify all the genes present in. (Science Daily)

    Comprehensive Strategy Seeks To Identify Structural Variation In Human Genome  Mar 17, 2006
    Such comparisons between mammalian genomes represent one of the most effective ways to pinpoint the roughly 5 percent of the 3-billion base pair human genome that is most obviously functional. According to computer modeling results, it is expected that comparisons among the 24 genome sequences will allow conserved sequences as small as six base pairs to be identified reliably ... Six base pairs is roughly the size of a transcription factor binding site: a small DNA sequence occurring near a gene... (Science Daily)

    Gene Influences Antidepressant Response  Mar 16, 2006
    Posted: March 15, 2006. Whether depressed patients will respond to an antidepressant depends, in part, on which version of a gene they inherit, a study led by scientists at the National Institutes of Health (NIH) has discovered. (Science Daily)

    'Looking' At Eyeless From Two Directions  Mar 11, 2006
    -- The Human Genome Project (HGP) endeavoured to map the human genome down to the nucleotide (or base pair) level and to identify all the genes present in. . (Science Daily)

    Detection of DNA on nanotubes offers new sensing, sequencing technologies  Feb 22, 2006
    Hybridization refers to the spontaneous binding of two complementary strands through base pair matching. By wrapping one strand of DNA around the surface of a carbon nanotube, the researchers can create a sensor that is targeted for a particular piece of complementary DNA. When the complementary DNA then binds to the DNA probe, the nanotube's natural near-infrared fluorescence is shifted slightly, and can readily be detected. (EurekAlert!)

    The complete art of RNA folding analysis  Feb 16, 2006
    Folding space analysis comprises various methods, such as suboptimal folding, computation of base pair probabilities, sampling procedures, and abstract shape analysis. Common to many approaches is the idea of partitioning the folding space into classes of structures, for which certain properties can be derived. (BioMed Central)

    Researchers Discover How to Detect Mutations  Jan 31, 2006
    What they found was that just a single base pair mutation in a DNA molecule can cause a significant change in the conductance of the molecule. The measurement is extremely sensitive; the alteration of a single base in the DNA stack can either increase or decrease the conductivity of a DNA helix, depending on the type of mismatched base. (Softpedia)


    Back to Health News

[ Terms Of Use | Privacy | About ]
©1998-2008 SurfWax, Inc.
All rights reserved. Patents pending.



Copyright SurfWax, Inc. 2008