SciBX: Science-Business eXchange Aug 29, 2008
Using CB2 agonists to treat pain. And more. (Nature News Service)
Nature Biotechnology Aug 29, 2008
Medical Research Council Cambridge CB2 0QH Britain. Lincoln University Chiristchurch New Zealand. (Nature News Service)
From a costume party to CB2 Aug 21, 2008
CB2 at last: Crate and Barrel offshoot CB2, the latest home furnishings store in the Bay Area, may also be among the most affordable ... Some of these designers are indeed mentioned in the store's latest catalog, where CB2 alludes to Emeco's midcentury classic aluminum chair designed for the Navy ... "We don't have a design team as such," said Ryan Turf, a textile and accessories buyer and developer for CB2. (San Francisco Chronicle)
Around the House: Affordable desks Aug 10, 2008
-- CB2 has priced its Graph desk at just $299 ... com or look for the desk upstairs at the new CB2 showroom at Union Square. (San Francisco Chronicle)
Turned-off Cannabinoid Receptor Turns On Colorectal Tumor Growth Aug 5, 2008
The team also analyzed the other main cannabinoid receptor, CB2, and found no role for it in colorectal cancer. They also treated the mice with a CB1 antagonist, a compound that binds to the receptor but does not activate it. (Science Daily)
Salutary Pizza Spice: Oregano Helps Against Inflammations Jun 27, 2008
Beta-caryophyllin docks on specific receptor structures in the cell membrane - the so-called cannabinoid-CB2 receptors, and produces a change in cell behaviour: for example, it will inhibit the cell ... But it has a further advantage in that, in contrast to other substances which affect the CB2 receptors, beta-caryophyllin does not lead to intoxication ... For this CB2 receptor has a "brother" by the name of CB1, which is best known to drug researchers. (Science Daily)
Opioids And Cannabinoids Influence Mobility Of Spermatozoids Jun 25, 2008
Dr. Agirregoitia has used a number of techniques to find three opioid receptors (DELTA, KAPPA and MU) and two cannabinoid receptors (CB1 and CB2) in the human sperm ... As regards the cannabinoid system, the activation of the CB1 y CB2 receptors causes the percentage of spermatozoids with rapid and progressive mobility to be reduced ... Even so, as a consequence of the activation of the CB1 receptor, the number of slow spermatozoids rises, while the activation of CB2 increases the number of... (Science Daily)
At Vintage Suites Jun 7, 2008
CB2 Architect and Construction of Portland, Ore. is the general contractor for the project, but a host of local sub-contractors have been hired to do the majority of the work. (Montana Standard, MT)
Japan's daily life Mar 3, 2008
A "toddler robot" called "Child-Robot with a Biomimetic Body," or "CB2," looks around the room. Hooked up to a database of words clustered by association, the robot -- dubbed Kansei, or "sensibility" -- responds to the word "war" by quivering in what looks like disgust and fear. (CNN -- International)
Should we take brain enhancing drugs? Dec 22, 2007
Barbara Sahakian and Sharon Morein-Zamir are at the University of Cambridge, Department of Psychiatry and the MRC/Wellcome Trust Behavioural and Clinical Neuroscience Institute, Cambridge CB2 2QQ, UK.. Abstract. (Nature News Service)
Medical Marijuana Growers Payback Dec 6, 2007
Another cannabinoid was found to attach to the CB2 receptor found on osteoclasts and osteoblasts, which are the cells reponsible for regulating bone density, and reduced bone loss in mice with induced mouse osteoporosis. It was also found that mice and humans with mutations to their CB2 receptors had three times more likelihood of contracting osteoporosis. (Washington Post)
The endocannabinoids: Functional roles and therapeutic opportunities Oct 15, 2007
Mice whose CB1 receptors are knocked out display slower functional recovery after TBI and do not respond to treatment with 2-AG. Over the last few years several groups have noted that CB2 receptors are also formed in the brain, particularly as a reaction to numerous neurological diseases, and are apparently activated by the endocannabinoids as a protective mechanism ... Activation of the CB2 receptor by a selective agonist also improved the neurological score ... Modulation of this system either... (EurekAlert!)
Complement C3 and Age-Related Macular Degeneration Aug 9, 2007
Box 139, Addenbrooke's Hospital, Cambridge CB2 0XY, United Kingdom, or at jrwy1{at}cam. ac. (New England Journal of Medicine)
Baby robot that can walk, talk and feel Jun 14, 2007
Built by Japanese scientists Minoru Asada and Hiroshi Ishiguro (who famously created an android twins of himself), the robot called CB2 weighs 33kg and stands 130cm tall ... When CB2's shoulders are tapped, it blinks as if surprised, stops moving, and turns its gaze toward the person who touched it ... Future research at the Japanese Science and Technology Agency in Osaka will attempt to improve the body functions of CB2 - whose full name is 'Child-robot with Biomimetic Body. (Yahoo News -- Robots and Robotics)
Marijuana Compound May Fight Lung Cancer Apr 20, 2007
In the new study, the researchers first showed that two different lung cancer lines, as well as samples from patient lung tumors, produced the cannabinoid receptors CB1 and CB2. Endocannabinoids -- cannabinoids produced naturally in the body -- are thought to have an effect on pain, anxiety and inflammation when they bind to cannabinoid receptors. (Forbes)
Marijuana Cuts Lung Cancer Tumor Growth In Half, Study Shows Apr 18, 2007
THC that targets cannabinoid receptors CB1 and CB2 is similar in function to endocannabinoids, which are cannabinoids that are naturally produced in the body and activate these receptors ... Acting through cannabinoid receptors CB1 and CB2, endocannabinoids (as well as THC) are thought to play a role in variety of biological functions, including pain and anxiety control, and inflammation ... In the present study, the researchers first demonstrated that two different lung cancer cell lines as... (Science Daily)
New JAK2 Mutations and Erythrocytosis Feb 1, 2007
Address reprint requests to Dr. Anthony R. Green at the Department of Haematology, Cambridge Institute for Medical Research, Hills Rd., Cambridge CB2 2XY, United Kingdom, or at arg1000{at}cam. ac. (New England Journal of Medicine)
Prevalence and Effects of Mutations in the Leptin-Receptor Gene Jan 18, 2007
Address reprint requests to Dr. Farooqi at the University Department of Clinical Biochemistry, Addenbrooke's Hospital, Hills Rd., Box 232, Cambridge CB2 2QQ, United Kingdom, or at isf20{at}cam. ac. (New England Journal of Medicine)
Hipper, younger, cheaper: Furniture retailers are redesigning themselves Aug 24, 2006
Crate and Barrel begat CB2 ... We were missing the younger customer," says Marta Calle, product director of CB2, who was previously at Crate and Barrel. ``We thought we could start developing a concept that would appeal to them in price and look." The first CB2 store opened in 2000 in a remote part of Chicago, she says ... Next year, CB2 will begin opening stores outside of Chicago. (Boston Globe)
Cannabis 'might harm conception' Aug 2, 2006
The cannabinoid receptors, CB1 and CB2, are present in the brain ... During early pregnancy a naturally occurring molecule called anandamide, required for normal embryonic development, activates CB1 and CB2. (BBC News -- Health)
Bowel study backs cannabis drugs Jun 1, 2006
However, the IBD patients had far greater numbers of CB2 receptors. The normal job of CB1 and CB2 receptors is to switch immune responses on or off. (Yahoo News -- Medical Marijuana)
Marijuana-like Compounds Suppress The Immune Response Apr 27, 2006
There are two types of cannabinoid receptor: the peripheral cannabinoid receptor (CB2) which is predominantly found in immune cells, and the central cannabinoid receptor (CB1) which occurs in the central nervous system. Recent studies have suggested that CB2 may be involved in a wide range of physiologic phenomena related to immunity, although research on this function is still at an early stage ... Among the possible immunological roles for CB2 is an involvement in the initiation of white blood... (Science Daily)
Kubby's Request Denied Mar 7, 2006
"Cannabinoids and their derivatives exert their effects via "central" CB1 receptors, mostly expressed in brain and responsible for cannabinoid psychoactivity, and "peripheral" CB2 receptors, mostly expressed in the immune system and unrelated to cannabinoid psychoactivity. Cannabinoids may be potential antitumoral agents owing to their ability to induce the regression of various types of tumors, including lung adenocarcinoma, glioma, and thyroid epithelioma. Although cannabinoids directly induce... (smokedot.org)
