Gene Variations May Predict Risk Of Breast Cancer In Women May 6, 2008
If confirmed through additional studies, adiponectin could be used along with TGF-beta and CHEK2, genes that have already been linked to breast cancer, to create a genetic testing model that will allow clinicians to more accurately predict breast cancer risk ... (May 17, 2004) Inheriting the wrong version of a gene called CHEK2 doubles a woman's risk of developing breast cancer, Cancer Research UK scientists confirm in a major new international study published in the. (Science Daily)
Gene Variant Increases Breast Cancer Risk Mar 19, 2008
(May 17, 2004) Inheriting the wrong version of a gene called CHEK2 doubles a woman's risk of developing breast cancer, Cancer Research UK scientists confirm in a major new international study published in the. . (Science Daily)
Rare cancer-causing syndrome found, for the first time, in Singapore Nov 5, 2007
They recruited 30 patients and their families, took detailed family histories and tested their blood for mutations in the p53 gene and the CHEK2 gene, another tumor suppressor gene found to be mutated in some patients with LFS.. They found LFS in one woman in Singapore who had been diagnosed with breast cancer at age 25. (EurekAlert!)
'Network' approach identifies potential breast cancer susceptibility gene Oct 10, 2007
Beginning with a list of four genes known to cause breast cancer when inherited in an abnormal form == BRCA1, BRCA2, ATM, and CHEK2 == the investigators gathered information from existing studies on connections between those "hub" genes and their gene partners. Those studies were of five kinds: expression profiles of genes whose activity mirrors that of the four hubs; surveys of gene activity when BRCA1 is shut down; published studies of biochemical interactions among proteins specified by the... (EurekAlert!)
Researchers find new gene linked to breast cancer Oct 8, 2007
The researchers started with four genes already known to play a role in breast cancer BRCA1, BRCA2, ATM and CHEK2. They were then able to see how each of these genes interacts with other genes in the body. (EurekAlert!)