West Nile's Targets Uncovered Aug 8, 2008
Symptoms range from mild flu-like symptoms to potentially fatal inflammation of the brain and central nervous system. West Nile is part of the flavivirus family, which includes dengue, yellow fever and tick- borne encephalitis viruses, among others, and causes thousands of deaths annually. (Science Daily)
One-Fifth of British Childhood Cancer Survivors Smoke Aug 8, 2008
Researchers learned those who had central nervous system cancers or heritable retinoblastoma were least likely to smoke, while survivors of Wilms' tumor, Hodgkin lymphoma or soft tissue sarcomas were most likely to report being a regular current smoker. Those treated with radiation or chemotherapy were less likely to be smokers than individuals who had not received that type of therapy. (MEDLINEplus)
Hopes of simple blood test for MS Aug 8, 2008
MS is a progressive disease of the central nervous system that affects the brain and spinal cord. Common signs can include fatigue, psychological changes, weakness or paralysis of limbs, numbness, vision problems, difficulties speaking or walking, bladder problems, and sexual dysfunction. (Yahoo News -- Multiple Sclerosis)
Physicists Provide 'Guiding Hands' For Proton Therapy Aug 7, 2008
This is especially valuable in cases such as craniospinal irradiation for pediatric Central Nervous System tumors or in the treatment of people with lung cancer where dose can be restricted to the tumor without affecting nearby tissue and organs. Currently two techniques are used for delivering proton beams. (Science Daily)
U.S. researchers uncover West Nile's targets Aug 7, 2008
Symptoms range from mild flu-like symptoms to potentially fatal inflammation of the brain and central nervous system. West Nile virus consists of only 10 proteins so it must hijack dozens of cellular processes of the host in order to infect individuals and replicate. (Xinhuanet, China)
One Fifth Of British Adult Survivors Of Childhood Cancer Smoke Despite Hazards Aug 5, 2008
When the researchers analyzed the responses by tumor site, they found that survivors of central nervous system cancers or heritable retinoblastoma were least likely to smoke, while survivors of Wilms tumor, Hodgkin lymphoma, or soft tissue sarcomas were most likely to report being a regular current smoker. Individuals who had been treated with radiation or chemotherapy were less likely to smoke than those who had not received that type of therapy. (Science Daily)
Single-Pill Combinations Diovan HCT and Exforge Approved in US as First-Line Treatments for High Blood Pressure Aug 4, 2008
About Novartis Novartis Pharmaceuticals Corporation researches, develops, manufactures and markets leading innovative prescription drugs used to treat a number of diseases and conditions, including those in the cardiovascular, metabolic, cancer, organ transplantation, central nervous system, dermatological, GI and respiratory areas. The company's mission is to improve people's lives by pioneering novel healthcare solutions. (PR Newswire)
'No alcohol in pregnancy' advised Aug 4, 2008
" FOETAL ALCOHOL SYNDROME Abnormal facial features Reduced growth Central nervous system abnormalities Impaired learning and memory skills Behavioural problems such as hyperactivity Jane Brewin, chief executive of the baby charity Tommy's, agreed, saying: "There is no proven safe level of alcohol to drink during pregnancy because any amount can pass through the placenta to the baby. " There is no consistent evidence that low to moderate consumption of alcohol during pregnancy has any adverse... (Yahoo News -- Alcohol and Alcoholism)
Elsie MacGill: First Female Aeronau... Aug 4, 2008
Polio is a viral disease that affects the central nervous system and may cause permanent or temporary paralysis. Staring at the grim prognosis of never walking again, Elsie refused to be daunted. (Suite101.com)
Transplant drug aids Huntington's Aug 4, 2008
It affects the central nervous system and can lead to loss of muscle control, dementia and depression. Huntington's normally affects people in middle age, but it can strike at any time. (Yahoo News -- Organ Donation & Transplants)
PML and MS Therapy Aug 3, 2008
The problem arises when these viruses are reactivated in the central nervous system of an immunocompromised person ... The common ground is that something substantially decreases the function of the immune system and for reasons that are not known, the virus re-emerges in an active form in the central nervous system. (Suite101.com)
Herpes Simplex and Varicella Zoster Aug 3, 2008
Such infections may also appear in nearby regions, such as the gums in the mouth and the anal area, and for individuals with compromised immune systems, HSV can spread to the central nervous system, causing meningitis and/or encephalitis. Regardless of the location of the active disease, the underlying pathophysiological process is similar. (Suite101.com)
MS forces women to go from employee of the year to living with a friend Aug 3, 2008
Then, in 2007, doctors diagnosed her with multiple sclerosis, a disease that attacks the central nervous system. While Mulhall struggles with fatigue, balance and bladder control, MS mostly has affected her ability to remember, solve problems and do other high-level mental tasks. (Atlanta Journal-Constitution -- Metro)
What I learned: Drumming is good for you Aug 3, 2008
Ekin also cites research by Andres Neher showing that drumming produces changes in the central nervous system and brain. The two brainwaves that are most applicable to the Drums Alive program are beta and alpha waves. (Pocatello Idaho State Journal, ID)
2000 North Carolina Technology Fast 50 Aug 3, 2008
Description: A privately held biotech company, Durham-based ICAgen uses proprietary "ion channel" technology to discover small-molecule therapeutics that can be used to treat cardiovascular, urinary, hematologic and central nervous system disorders ... In March, ICAgen signed a collaborative agreement with the third-largest pharmaceutical company in Japan, Yamanouchi Pharmaceutical Co. Ltd., to develop products to treat central nervous system disorders. (Charlotte Business Journal, NC)
West Nile virus found in Addison County Aug 2, 2008
Approximately one percent of people who are infected develop severe illness affecting the central nervous system, such as encephalitis or meningitis, which can be fatal. The Department of Health encourages Vermonters to take steps to protect themselves from mosquitoes including getting rid of standing water where mosquitoes may breed, using bug repellent, and repairing or installing window and door screens. (Barre Montpelier Times Argus)
Multiple Sclerosis: new MRI contrast medium enables early diagnosis in animal model Aug 2, 2008
MS is a chronic inflammatory disease of the central nervous system of unknown cause. It usually begins in young adults, and women are affected more frequently. (EurekAlert!)
BioMS Medical completes patient recruitment in phase III U.S. multiple sclerosis trial Aug 1, 2008
MBP8298 (dirucotide) is being developed for the potential treatment of multiple sclerosis (MS), an autoimmune disease caused by immune attack against normal components of the central nervous system ... MS is caused by damage to myelin, the protective sheath surrounding nerve fibers in the central nervous system, which interferes with messages from the brain to the body. (Canada Newswire)
Scientists Turn Skin Cells Into Motor Neurons in ALS Patients Aug 1, 2008
"Because the disease process is happening in the spinal cord in the central nervous system of patients, we don't at all have access to living examples of the neurons that are undergoing the disease process. . . . No way could we go to ALS patients and take samples of their motor neurons.". The scientists had originally planned to use somatic cell nuclear transfer (SCNT), or "therapeutic cloning," to try to accomplish this feat. (U.S. News & World Report)
Protein Made By Fat Cells May Increase Risk Of Heart Attack In Older Adults Aug 1, 2008
Adiponectin has been shown to increase energy expenditure through direct actions in the central nervous system in mice, and if this effect were also present in humans, it could be significantly harmful in older adults by accelerating the loss of skeletal muscle, a condition called sarcopenia. "This study shows that this abundant product of fat cells is a marker and perhaps even a mediator of worsened outcomes in persons aged 65 years and older," said Dr. Kizer. (Science Daily)
Scientists create first personalized stem cells in ALS patients Aug 1, 2008
They also found evidence of glial cells, a crucial component of the central nervous system. ALS is caused by the degeneration of motor neurons, but until now scientists have had no way to take samples from patients and study them in the lab, said Christopher Henderson, a professor of pathology, neurology and neuroscience at Columbia and coauthor of the study. (Los Angeles Times)
Possible Cause of Postpartum Depression Pinpointed Aug 1, 2008
Mouse study implicates GABA receptors in the central nervous system ... Neurosteroids are produced in the central nervous system from steroid hormones such as progesterone. (MEDLINEplus)
Multiple Tumors in a Child with Germ-Line Mutations in TP53 and PTEN Jul 31, 2008
1 A germ-line mutation of the PTEN gene is associated with Cowden's syndrome of familial susceptibility to multiple hamartomas and to cancers of the breast, thyroid, and central nervous system. 2 We describe a child who inherited mutations of both TP53 and PTEN.. (New England Journal of Medicine)
Nurses' Notes - Brains are intricate, delicate and need to be protected Jul 30, 2008
This highly complex organ controls the central nervous system, containing roughly 100 billion nerve cells. It needs a lot of oxygen in order to do its work, so it has an intricate system of vessels delivering oxygenated blood to the cells. (Missoulian, MT)
She's not just 'The Girl With MS' Jul 30, 2008
She wants to speak out for better treatment of MS, a debilitating disease that attacks the central nervous system, without becoming a poster child. It's a delicate balancing act. (OregonLive, OR -- News)
Biovail Founder Melnyk Drops Challenge to Board Election; Forms New Firm Jul 29, 2008
They proposed competing strategies to combat flagging sales of Biovail's two biggest-selling drugs, the antidepressant Wellbutrin XL and blood-pressure medicine Cardizem LA. Biovail will cut costs and focus on drugs for central nervous system disorders, including multiple sclerosis. Melnyk wanted to pursue hard-to-formulate generic medicines. (Bloomberg -- Canada)
Are you limiting kids' cell phone use? Jul 29, 2008
Herberman bases his concerns on early unpublished data looking at how electromagnetic radiation emitted by mobile phones may affect human cells in the brain and central nervous system. Groups in the UK, France and India have also called for limiting children s cell phone use out of similar concerns. (Atlanta Journal-Constitution -- Health)
Geographical Pattern Eyed in 1991 Gulf War Cases of ALS Jul 29, 2008
ALS causes cellular degeneration in the central nervous system. Its cause is unknown. (MEDLINEplus)
Cancer Center: Cell Phone Risk Jul 27, 2008
Though studies are being done to see if there is a link between it and tumors of the brain and central nervous system, there is no definitive link between the two, the institute says on its Web site. "By all means, if a person feels compelled that they should take precautions in reducing the amount of electromagnetic radio waves through their bodies, by all means they should do so," said Dan Catena, a spokesman for the American Cancer Society. (Time.com)
Caffeine for Alzheimer's Prevention Jul 26, 2008
Like a protective wall, the BBB keeps toxins in the circulatory system from entering the central nervous system and causing damage. Unfortunately, a high cholesterol diet can damage the blood brain barrier, causing it to leak, and leaving the brain vulnerable to injury and disease. (Suite101.com)
* US swimmer Hardy planning to appeal positive doping test Jul 26, 2008
Clenbuterol, often used on racing horses, helps boost aerobic capacity and aids the bodys flow of oxygen as well as stimulating the central nervous system. It is prescribed for people with asthma in some cases. (Taipei Times, Taiwan -- World)
HP's plan to fix ailing planet Jul 26, 2008
Hewlett Packard is up to two years away from starting to build a "central nervous system for the Earth", known as CeNSE. ... " Hard nosed For HP's central nervous system to become a reality, Dr Williams said the world had to be covered with sensors. "We can and should be able to make these sensors by the billions and eventually even trillions using these highly integrated manufacturing processes that have been developed for the computer chip industry and the electronics industry," he said.... (BBC News -- Science)
Garden Q&A: Soil and thrips can carry diseases that kill impatiens Jul 26, 2008
There is a substance in these plants that can produce vomiting, drooling, weakness and central nervous system depression. - Oleander: This common ornamental plant contains toxins that can irritate the gastrointestinal tract, cause hypothermia and potentially serious cardiac problems. (Florida Times-Union)
Studies conclude impurity in Roche's Viracept did not increase patients' risk of cancer Jul 25, 2008
Roche is the world leader in in-vitro diagnostics and drugs for cancer and transplantation, a market leader in virology and active in other major therapeutic areas such as autoimmune diseases, inflammation, metabolic disorders and diseases of the central nervous system. In 2007 sales by the Pharmaceuticals Division totalled 36. (EurekAlert!)
Hidden Toxins in Baby's Nursery Jul 24, 2008
Disinfecting wipes, sprays, air fresheners, and room deodorizers contain chemicals that are known irritants to the eyes, mucous membranes, and central nervous system. They also contain pesticides. (Suite101.com)
GPISD board unanimously OKs random drug testing Jul 24, 2008
Cocaine metabolite (central nervous system stimulant; crank, crystal). Opiates (pain killer; Oxycodone, Darvocet, Vicodin). (North Channel Sun, TX)
Pa. parents sue FirstEnergy over girl’s illness Jul 23, 2008
The girl s doctors have recommended future medical tests on her kidneys, lungs and central nervous system to monitor her exposure to the toxic and hazardous materials, the suit said. The environmental group PennFuture sued FirstEnergy last year, claiming the plant violated visible emissions standards at least 250 times between November 2002 and March 2007. (Somerset Daily American, PA)
Prenatal Drinking, Environmental Enrichment: Effects On Neurotrophins Are Independent Of Each Other Jul 23, 2008
Prenatal alcohol exposure affects physical and central nervous system development. . (Science Daily)
Reduce your risk of falls by tracking medications Jul 23, 2008
A common feature is that they depress the central nervous system, making patients less alert and slower to react. Bottom line: "Anything that can cause drowsiness can put you at increased risk of falling," says Stefanie Ferreri, a pharmacy professor at the University of North Carolina at Chapel Hill, who led the research. (OregonLive, OR -- News)
Researchers probe geographical ties to ALS cases among 1991 Gulf War veterans Jul 22, 2008
Also known as Lou Gehrig's Disease because it crippled and ultimately killed that baseball great in 1941, ALS causes cellular degeneration in the central nervous system. Its cause is unknown. (EurekAlert!)
Scientists figure out how the immune system and brain communicate to control disease Jul 22, 2008
It may be more effective to take advantage of the central nervous system to control cells of the spleen. This way, "you know where the treatment is going," said Dr. Rosas-Ballina. (EurekAlert!)
Roche Makes Offer to Acquire All Outstanding Shares of Genentech for US$89.00 Per Share in Cash Jul 21, 2008
It is also active in other major therapeutic areas such as autoimmune diseases, inflammatory and metabolic disorders and diseases of the central nervous system. In 2007, sales by the Pharmaceuticals Division totaled 36. (PR Newswire)
Pediatric Cancer Foundation launches clinical trials Jul 19, 2008
The trial is designed for patients 17 years old and younger with solid tumors, including lymphoma and tumors of the central nervous system, who have progressed or relapsed despite standard treatment, and who have a life expectancy of greater than 12 weeks. The trial is co-authorized by Dr. Michael Nieder of All Children's Hospital in St. Petersburg and Dr. Lia Gore at the. (Tampa Bay Business Journal, FL)
Moms: How to stop feeling so tired Jul 18, 2008
Having caffeine, a central nervous system stimulant, too close to bedtime is also going to make it difficult to fall asleep. And since caffeine is a diuretic, it might make you get up in the night to use the bathroom. (CNN -- Health)
Michael J. Fox set for role on FX's `Rescue Me' Jul 17, 2008
He quit acting full time in 2000 because of his symptoms, which for people living with Parkinson's - a chronic, progressive disorder of the central nervous system - can include muscle rigidity, tremor and slowness of movement ... Parkinson's disease is a chronic, progressive disorder of the central nervous system that leaves patients increasingly unable to control their movements. (FOX 11, AZ)
Lyme disease Jul 16, 2008
The most severe symptoms include painful arthritis, headaches and heart or central nervous system problems. Initial symptoms occur within three to 30 days of transmission, and treatment involves antibiotics. (Auburn Citizen, NY)
Weeding Out The Highs Of Medical Marijuana Jul 16, 2008
"So some current research is focused on designing drugs that only target cannabinoid receptors in the part of the body relevant to the disease in question and not the receptors in the central nervous system involved in the unwanted effects of cannabis.". A further approach to avoiding the psychoactivity caused by THC involves harnessing the body's own cannabis, called 'endocannabinoids. (Science Daily)
Noven names chief medical officer Jul 15, 2008
"He will direct our clinical, regulatory and medical affairs activities for both our transdermal and oral products, helping design and execute our clinical plans, and leading developmental products through the regulatory process toward commercialization. His experience in the areas of women's health and central nervous system conditions complements our current areas of therapeutic focus, and his leadership in product selection and development should help us execute on new product opportunities... (South Florida Business Journal, FL)
Golfer describes life after lightning strike Jul 14, 2008
No two strikes are alike, but every single person I talked to [who survived a lightning strike] had central nervous system issues, which does not show up on any kind of physical. At the time I was struck, I was 64, retired and financially able to go on in life. (Atlanta Journal-Constitution -- Metro)
Dr. Charles J. McCabe, inspired generations of medical students Jul 13, 2008
About to launch a surgical career in 1979, Dr. McCabe was diagnosed with multiple sclerosis, which affects the central nervous system. Because he could not perform surgery, he became a teacher and rose to become associate chief of emergency services at the hospital. (Boston Globe)
Rabies nowin Bladen Jul 13, 2008
According to the Centers for Disease Control, rabies is a disorder that attacks the central nervous system and can be fatal to the infected animal. It can be passed from one animal to another usually through a bite. (Elizabethtown Bladen Journal, NC)
Japanese Encephalitis Virus Causes 'Double Trouble' To Brain Jul 13, 2008
The children are more vulnerable targets of this virus, which causes massive neuronal loss in the Central Nervous System. "Children are at a dynamic stage of brain development, hence infection at this stage can have devastating effects on mental functions later in life. Our study has tried to explore how JEV infection leads to development of long-term cognitive deficits in the survivors", says Dr. Anirban Basu who has been working in the neurobiology of JEV infection for the past 4 years. (Science Daily)
Controversial autism therapy may get tested Jul 13, 2008
And there is evidence chelation may redistribute metals in the body, perhaps even into the central nervous system. Don't Miss. (CNN -- Health)
Some drugs increase risk of falling: UNC researchers Jul 13, 2008
The common denominator among them is that they all work to depress the central nervous system, which can make patients less alert and slower to react. Stefanie Ferreri, Pharm. (EurekAlert!)
Hopes of simple blood test for MS Jul 13, 2008
MS is a progressive disease of the central nervous system that affects the brain and spinal cord. Common signs can include fatigue, psychological changes, weakness or paralysis of limbs, numbness, vision problems, difficulties speaking or walking, bladder problems, and sexual dysfunction. (Yahoo News -- Multiple Sclerosis)
Door-to-door: Jul 13, 2008
Methamphetamine, also known as speed, crank, crystal or ice, is an illegal drug that stimulates the central nervous system. It can be snorted, smoked, injected or taken by mouth. (San Diego Union-Tribune)
What Is Tetanus or Lockjaw Jul 6, 2008
When the tetanus toxin is released from the bacterium, it gets cleaved into two associated fragments and it is able to bind to and be transported within the nerve fibers outside of the central nervous system back into the nervous system. When it is transported up into the spinal cord it begins to cause its hallmark problems. (Suite101.com)
'No alcohol in pregnancy' advised Jul 4, 2008
" FOETAL ALCOHOL SYNDROME Abnormal facial features Reduced growth Central nervous system abnormalities Impaired learning and memory skills Behavioural problems such as hyperactivity Jane Brewin, chief executive of the baby charity Tommy's, agreed, saying: "There is no proven safe level of alcohol to drink during pregnancy because any amount can pass through the placenta to the baby. " There is no consistent evidence that low to moderate consumption of alcohol during pregnancy has any adverse... (Yahoo News -- Alcohol and Alcoholism)
Researchers Are First To Simulate The Binding Of Molecules To A Protein Jul 4, 2008
"Many enzymatic reactions also require ATP. In the central nervous system, the transport of hormones, neurotransmitters or other molecules, these are all ATP-dependent.". "It has been estimated that you burn more than your body weight in ATP every day," he said. (Science Daily)
An Israeli Biotech Company Plays the Field Jul 4, 2008
They include drugs for treating cardiovascular, central nervous system, inflammatory, and oncological diseases and conditions. To fund this ambitious beauty contest, BioLineRX has raised more than $100 million via several rounds of venture capital and government funding, and an initial public offering on Feb. 7. (BusinessWeek)
Transplant drug aids Huntington's Jul 3, 2008
It affects the central nervous system and can lead to loss of muscle control, dementia and depression. Huntington's normally affects people in middle age, but it can strike at any time. (Yahoo News -- Organ Donation & Transplants)
Neurobiological Technologies' CEO to retire Jul 3, 2008
Neurobiological, which is focused on acquiring and developing central nervous system-related drug candidates, has a treatment for acute ischemic stroke, Viprinex, currently in a late-stage trial. That drug is derived from the venom of the Malayan pit viper. (East Bay Business Times, CA)
Evotec's EVT 101 Well Tolerated in Four Week Higher Repeat Dose Safety Study Jul 3, 2008
In proprietary projects, Evotec specializes in finding new treatments for diseases of the Central Nervous System. Evotec has three programs in clinical development: EVT 201, a partial positive allosteric modulator (pPAM) of the GABAA receptor complex for the treatment of insomnia, EVT 101, a subtype selective NMDA receptor antagonist for the treatment of Alzheimer's disease and/or pain, and EVT 302, a MAO-B inhibitor in development for smoking cessation. (Primezone Releases)
Drink up as summer heats up to avoid dehydration Jul 3, 2008
Heat stroke is more serious; it damages the central nervous system and is marked by severe confusion, impaired judgment and seizures or blackouts. Sawka says heat injury falls in between. (USA Today)
Novartis Pharmaceuticals Corporation to Appeal Judgment in Alabama Pricing Case Jul 2, 2008
About Novartis Novartis Pharmaceuticals Corporation researches, develops, manufactures and markets leading innovative prescription drugs used to treat a number of diseases and conditions, including those in the cardiovascular, metabolic, cancer, organ transplantation, central nervous system, dermatological, GI and respiratory areas. The company's mission is to improve people's lives by pioneering novel healthcare solutions. (PR Newswire)
