Medical examiner: Inmate died from natural causes Aug 28, 2008
The report notes Chance had a history of HIV, hypertension and hepatitis C seropositivity, with cirrhosis of the liver and cachexia, a wasting syndrome that causes weight and muscle loss. Reilly said he had reviewed the medical records and interviewed the prison's medical director himself following the death, and that the prison would await the release of Hellman's report before revealing the findings of its own investigation. (The Delaware County Times, PA)
Study Identifies Protein That Produces 'Good' Fat: Finding May Lead To Ways To Treat, Prevent Obesity Aug 21, 2008
The protein has a potential use in the treatment of obesity and cachexia (morbid weight loss). (May 14, 2008) Scientists elucidate the molecular pathway that induces cells to become energy-burning brown fat cells as opposed to energy-storing white fat. (Science Daily)
Gene Therapy Improves Survival And Quality Of Life Of Dogs With Cancer: Could It Also Help Humans? Jun 17, 2008
If cachexia--muscle wasting and severe weight loss--develops, it can prevent cancer-specific therapy from being given and may be a direct cause of death ... VGX Pharmaceuticals Inc. is also waiting for approval from the Food and Drug Administration to study the GHRH treatment in humans with cancer cachexia, Draghia-Akli said. (Science Daily)
'Connecting The Dots' In Path That Leads To Fat Apr 12, 2008
The protein has a potential use in the treatment of obesity and cachexia (morbid weight loss). (Oct. (Science Daily)
Galea Life Sciences' Subsidiary Awarded Presentation Slot for Clinical Policy Abstract At 15th International Symposium on HIV and Emerging Infectious Diseases Apr 1, 2008
The clinical policy abstract is titled, ``Micronutrients and High Protein Supplementation in the Treatment of Catabolic Cachexia and the Improvement in the Quality of Life in the Era of HAART,'' (Abstract #A-081-0008-00269) ... Catabolic Cachexia is a term used to describe the gradual breakdown of muscle and skeletal components associated with disease. (Primezone Releases)
US Retiree Couples Need $225000 for Health Costs: Report Mar 7, 2008
Study leader Professor Goeran Andersson said it may be possible to develop new anti-obesity treatments that inhibit the action of TRAP. He also said the protein "is potentially useful in the treatment of conditions involving morbid cachexia (weight loss), such as cancer diseases," AFP reported. The research was published online Wednesday in the journal Public Library of Science. (BusinessWeek)
Protein that could fight obesity Mar 7, 2008
"This protein is potentially useful in the treatment of conditions involving morbid cachexia (weight loss), such as cancer diseases," professor Goeran Andersson, who led the study, said. "The discovery can also lead to new ways of treating obesity based on the inhibition of this protein's effect," he said. (iAfrica.com)
Explaining Chemotherapy-associated Nausea Feb 4, 2008
Anorexia (loss of appetite) and cachexia (a syndrome of physical wasting and weight loss) often accompany chemotherapy-induced symptoms of nausea and vomiting. These side effects can compromise the patient's nutritional status and impede recovery. (Science Daily)
GLAXOSMITHKLINE AND GALAPAGOS ENTER STRATEGIC ALLIANCE TO DEVELOP ... Dec 10, 2007
Galapagos (Euronext Brussels, GLPG; Euronext Amsterdam, GLPGA; London AiM: GLPG) is a drug discovery company with pre-clinical programs in bone and joint diseases and cachexia. Its division BioFocus DPI offers a full suite of target-to-drug discovery products and services to pharmaceutical and biotech companies, encompassing target discovery and validation, screening and drug discovery through to delivery of pre-clinical candidates. (CNNMoney.com)
First Patient Enrolled in Phase II Cancer Trial Oct 3, 2007
According to Dr. Chasen, "AVR118 may offer a new treatment paradigm in palliative care. Early identification and treatment of patients will hopefully enable us to reduce the severely debilitating effects of cachexia and chemotherapy." Enrollment initially will include 14 patients between the ages of 18 and 85 who have recurrent or advanced malignancies and are suffering from symptoms of cachexia, including muscle wasting, severe fatigue and loss of appetite ... Its initial compound AVR118... (Canada Newswire)
Cancer and Nutrition Sep 14, 2007
Conditions like anorexia or the loss of appetite and cachexia, a wasting syndrome, can develop as a result of malnutrition. Eating well has been linked to better prognoses. (Suite101.com)
GTx, Inc. (GTXI) Chief Executive Officer to Ring the NASDAQ Stock Market Opening Bell Sep 1, 2007
GTx also is developing Ostarine(TM), a first-in-class selective androgen receptor modulator, or SARM. GTx has initiated a Phase IIb Ostarine(TM) clinical trial for cancer cachexia and plans to initiate a Phase IIb Ostarine(TM) clinical trial for the treatment of chronic kidney disease muscle wasting by the end of 2007. GTx believes that Ostarine(TM) also has the potential to treat a variety of other indications associated with muscle wasting and bone loss including sarcopenia and osteoporosis. (Primezone Releases)
GTx's Q2 loss shrinks Aug 1, 2007
The company next year will also complete two trials for Ostraine, a treatment for cancer cachexia and chronic kidney disease. The company spent $8. (Memphis Business Journal, TN)
GTx's Q1 loss narrows May 5, 2007
"The two Phase III ACAPODENE trials are proceeding on schedule, and plans are underway for the initiation of the Phase IIb Ostarine cancer cachexia clinical trial by June and the Phase IIb Ostarine chronic kidney disease muscle wasting clinic trial by the end of the year.". Mitchell added that GTx, a biopharmaceutical company based in Memphis, has made progress in recruiting "top scientific, clinical and business talent to GTx to expand our capabilities to prepare the new drug applications for... (Memphis Business Journal, TN)
Fish Oil May Help Kidney Disease Sufferers May 1, 2007
"EPA has been used successfully in other population groups with chronic inflammation including people with osteoarthritis and cancer cachexia, however the anti-inflammatory effects have not yet been applied to patients on dialysis," she said. As part of Ms Zabel's study, participants will be given a daily dose of fish oil, and tests will be conducted to measure changes in inflammation and appetite. (Science Daily)
Immunotec Inc.: First Reporting Following Reverse Take-Over Transaction of Magistral Biotech Inc. Apr 4, 2007
Management is of the opinion, that its investment in current research in such areas as cancer cachexia, prostate health, aging and aging related conditions will enable Immunotec to produce and bring to market more value added products which will continue to differentiate its products from competing products. FORWARD LOOKING STATEMENTS. (CCNMatthews Press Releases)
Vicus Therapeutics Announces Participation at 14th International Molecular Medicine Tri-Conference Mar 1, 2007
Vicus's lead program, VT-122, is in Phase II clinical trial for the treatment of cancer cachexia in patients with advanced lung cancer. Additionally, Vicus has two preclinical programs for the treatment of oral mucositis and cancer fatigue. (PR Newswire)
7000 Cedis (68 Cents) A Day Per Prisoner!!! Feb 10, 2007
Others are malaria fever, 4 %; congestive cardiac failure, 4 %; meningitis, 3 %, hypertension renal failure and respiration failure, 2 % each; asthma, cirrhosis of the liver, diabetes, epilepsy, haemoptisis, hernia, paralysis and cachexia each accounted for 1 % of prisoners deaths. This is exclusive of individuals who have been subjected to mob action before they were sentenced to prison. (Ghana Web, Ghana)
Obesity Triples The Risk Of Chronic Kidney Failure May 14, 2006
Posted: May 13, 2006. Obesity is an important and potentially preventable risk factor for chronic renal failure (CRF), according to a study in the June Journal of the American Society of Nephrology. (Science Daily)
Pot as a medicine? No way says FDA Apr 24, 2006
The American Medical Association recognizes that marijuana can have a great use in H IV wasting, in c ancer cachexia, c hemotherapy-induced nausea and vomiting and in glaucoma (a condition where the pressure in the eye is raised). But the AMA has called for "further adequate and well-controlled studies of marijuana and related cannabinoids." Until such studies do take place, the AMA recommends that marijuana be placed in Schedule 1. (Food Consumer)
Pfizer to Expand Neuroscience Research With Acquisition of Biotech Company Rinat Neuroscience Apr 7, 2006
Rinat has additional compounds in late pre-clinical development for migraine prophylaxis and cachexia as well as discovery programs in obesity, pain, neuropathy and Parkinson's disease. The acquisition is subject to customary closing conditions (including approval under the Hart-Scott-Rodino Antitrust Improvements Act of 1976), and is expected to close by mid-year 2006. (PR Newswire)
Thiamin deficiency common in hospitalized heart failure patients Jan 14, 2006
"Patients with advanced heart failure commonly suffer from cardiac cachexia, but little is known about the mechanisms underlying this problem or how to treat it. Deficiency in one dietary component, such as thiamin, is unlikely to occur in isolation and might be a marker for shortages of other micronutrients. Recent research suggests that targeted multi-micronutrient supplementation may improve quality of life and left ventricular function in elderly patients with heart failure," Dr. Cleland... (EurekAlert!)
Serono Completes Second Phase III Trial of its Proprietary Recombinant Human Growth Hormone for HIV-Associated Adipose Redistribution Syndrome (HARS) Jan 9, 2006
Serono's r-hGH products are indicated for the treatment of pediatric growth hormone deficiency, adult growth hormone deficiency, HIV wasting or cachexia and for the treatment of short bowel syndrome. Growth hormone should be used with caution in patients with insulin resistance, glucose intolerance, diabetes, and in women who are pregnant or nursing. (PR Newswire)
