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    News and Articles on DNA sequence



    On the Origin of Nematodes: Phylogenetic Tree of World's Most Numerous Group of Animals  Nov 21, 2009
    It contains over 1,200 species and is entirely based on the analysis of DNA sequence data ... A phylogenetic tree of nematodes based on about 1200 full-length small subunit ribosomal DNA sequences. (Science Daily)

    New Maize Map to Aid Plant Breeding Efforts  Nov 20, 2009
    In constructing the haplotype map, the researchers identified several million genetic variations -- or polymorphisms -- in the DNA sequence among the 27 maize inbred lines, as well as 10-fold to 30-fold variation in the rates at which genes recombine. "This approach yielded evidence that points to hundreds of regions in the genome that were probably involved in the domestication of maize and-or geographic differentiation among various lines of maize," Ross-Ibarra said. (Science Daily)

    U.S. scientists uncover maize's full genetic code  Nov 20, 2009
    In constructing the haplotype map, the researchers identified several million genetic variations - or polymorphisms - in the DNA sequence among the 27 maize inbred lines, as well as 10-fold to 30-fold variation in the rates at which genes recombine. "Having the complete genome in hand will make it easier to breed new varieties of corn that produce higher yields or are more tolerant to extreme heat, drought, or other conditions," said senior author Richard Wilson, director of Washington... (Xinhuanet, China)

    Scientists Crack Corn Code: Reference Genome of Maize, Most Important US Crop  Nov 20, 2009
    19, 2009) A four-year, multi-institutional effort co-led by three Cold Spring Harbor Laboratory (CSHL) scientists culminated today in publication of a landmark series of papers in the journal Science revealing in unprecedented detail the DNA sequence of maize (Zea mays) ... D., CSHL Professor, co-principal investigator on the maize genome project, and a pioneer in genome sequencing efforts, "is that it provides a reference DNA sequence for the most important agricultural crop in the U.S., making... (Science Daily)

    Exploration By Explosion: Studying The Inner Realm Of Living Cells  Nov 13, 2009
    It contains over 1,200 species and is entirely based on the analysis of DNA sequence. (Aug. (Science Daily)

    Scientists find out why language is unique to humans  Nov 13, 2009
    They focused on gene expression, the process by which a gene's DNA sequence is converted into cellular proteins, and discovered that the human and chimp forms of FOXP2 produce different effects on gene targets in the human cell lines. Geschwind said this suggests that FOXP2 drives these genes to behave differently in the two species. (Xinhuanet, China)

    Why Can't Chimps Speak? Gene Differences Key  Nov 12, 2009
    " FOXP2 switches other genes on and off. Geschwind's lab scoured the genome to determine which genes are targeted by human FOXP2. The team used a combination of human cells, human tissue and post-mortem brain tissue from chimps that died of natural causes. The chimp brain dissections were performed in the laboratory of coauthor Todd Preuss, associate research professor of neuroscience at Emory University's Yerkes National Primate Research Center. The scientists focused on gene expression -- the... (Science Daily)

    Scientists Reveal How Induced Pluripotent Stem Cells Differ From Embryonic Stem Cells  Nov 10, 2009
    And now scientists have detected a remarkable if subtle molecular disparity between the two: They have distinct "epigenetic" signatures; that is, they differ in what gets copied when the cell divides, even though these differences aren't part of the DNA sequence ... This chemical change which, associated with silencing genes, is classified as epigenetic because, although not part of the DNA sequence, is copied when a cell divides. (Science Daily)

    Danny Henley: Blame it on the genes  Nov 10, 2009
    U.S. researchers report finding that people with a particular gene variant performed more than 20 percent worse on a driving test than people with a different DNA sequence. Approximately 30 percent of Americans have the variant, according to the research team at the University of California Irvine. (Belmont Citizen Herald, MA)

    Infotainment  Oct 31, 2009
    They found that people with a particular gene variant performed more than 20 percent worse on a driving test than people with a different DNA sequence. The study may explain. (Daily Times, Pakistan)

    American energy security could come from trees  Oct 31, 2009
    As such, the federal government is currently spending millions of dollars to map the DNA sequence of the eucalyptus - bringing in expert partners on eucalyptus and biotechnology such as ArborGen to help fulfill this mission. "We want to help create a viable solution to the increasing energy demands at a time when our traditional supply is being depleted," says Wells. (Lake City Reporter, FL)

    Circadian Surprise: Mechanism Of Temperature Synchronization In Drosophila  Oct 30, 2009
    "This study demonstrates once again the power of forward genetics in identifying novel factors and mechanisms. Just looking at the nocte DNA sequence, no one would have predicted a function for this gene or the chordotonal organs in temperature synchronization". The researchers include Hana Sehadova, Queen Mary College, University of London, London, UK; Franz T. Glaser, Institut fur Zoologie, Universitat Regensburg, Regensburg, Germany; Carla Gentile, Queen Mary College, University of London,... (Science Daily)

    Maternal Mice Fed High-Fat Diet Produce Larger Pups  Oct 28, 2009
    This work adds to the growing body of research in epigenetics, the study of heritable alterations in gene expression that act independently of changes in DNA sequence. Until very recently, scientists believed that our genes were the sole carrier of hereditary information. (Science Daily)

    First Ever Method To Genetically Identify All Eight Tuna Species  Oct 28, 2009
    The analysis of the DNA sequence variability of two unlinked genetic markers, one a hypervariable segment of the mitochondrial genome and the other a nuclear gene, enables full discrimination between all eight tuna species. "This methodology will allow the identification of tuna species of any kind of tissue or type or presentation -- including sushi and sashimi," said Dr Jordi Vi;as of Girona University. (Science Daily)

    Genome Of Microbe Silently Shaping Ecology Of Ocean Dead Zones Described  Oct 24, 2009
    "We obtained enough DNA sequence coverage from the community of microbes to actually assemble a continuous stretch representing what we are calling the SUP05 metagenome -- it's a composite of the entire SUP05 population spanning the various environmental samples that we sequenced.". Susannah Tringe, a metagenomics scientist at the DOE JGI, said that the OMZs are sinks for an essential nutrient that marine organisms need to survive--nitrogen--as well as sources for the greenhouse gases methane... (Science Daily)

    Trembling hands and molecular handshakes  Oct 24, 2009
    This mutation is found on the X chromosome in one out of 800 men, and involves abnormal expansions of a DNA sequence composed of repeats of the base triplet CGG. Healthy people have between 5 and 54 copies of this sequence, while those who will develop FXTAS are born with between 55 and 200 repeats. Expansion of the triplet sequence beyond 200 copies leads to Fragile X Syndrome (FXS), which is the second most common cause of hereditary mental retardation after Down's syndrome. (EurekAlert!)

    Less Sensitivity to Hormone May Play Role in Autism  Oct 23, 2009
    This genetic signature doesn't involve changes to DNA sequence itself, but rather to the way that genes are switched on and off, said the team from Duke University Medical Center in Durham, N.C. They found that people with autism have a higher-than-normal number of gene-regulating molecules called methyl groups in a region of the genome that regulates oxytocin receptor expression. "In both blood samples and brain tissue, the methylation status of specific nucleotides in the oxytocin receptor... (MEDLINEplus)

    Possible Link Between Autism And Oxytocin Gene Via Non-DNA Sequence Mutation  Oct 23, 2009
    22, 2009) Researchers at Duke University Medical Center have uncovered a new genetic signature that correlates strongly with autism and which doesn't involve changes to the DNA sequence itself. Rather, the changes are in the way the genes are turned on and off. (Science Daily)

    No Such Thing As 'Junk RNA,' Say Researchers  Oct 19, 2009
    (May 15, 2008) RNA is best known as a working copy of the DNA sequence of genes. In this role, it's a carrier of the genes' instructions to the cell, which manufactures proteins according to information in the RNA. (Science Daily)

    TraDIS technique tackles typhoid  Oct 17, 2009
    "By combining transposon-induced mutagenesis a method whereby small chunks of cut-and-paste DNA sequence are inserted into the genome effectively disabling individual genes and high-throughput sequencing, we have been able to determine which genes are essential for the survival of S. Typhi and which are non-essential.". "Crucially, our new method allows us to achieve all this in just a single experiment.". (EurekAlert!)

    Using RNAi-based Technique, Scientists Find New Tumor Suppressor Genes In Lymphoma  Oct 15, 2009
    The findings of this study are a vital complement to genomics approaches to map the cancer genome, the altered DNA sequence of cancer patients. While this strategy will help build a catalog of every genetic mutation lurking within a cancer cell s DNA, our approach offers functional information, such as which genes are causally involved in promoting cancer -- knowledge that can be exploited to design better, targeted therapies, said Professor Scott Lowe, Ph. (Science Daily)

    In net age, learning to think in petabytes  Oct 13, 2009
    It sounds like science fiction, but soon youll hand a machine a strand of hair, and a DNA sequence will come out the other side, said Jimmy Lin, a professor at the University of Maryland. While consumers are just starting to comprehend the idea of buying external hard drives for the home capable of storing a terabyte of data, computer scientists need to grapple with data sets thousands of times as large and growing ever larger. (India Times, India -- Health/Science)

    Micromanaging Cancer  Oct 8, 2009
    1 The previous model was that gene expression was activated during transcription, the process of copying the DNA sequence into RNA, when transcription factor proteins bind to promoter sequences in DNA upstream of the gene's coding sequence. Now it is clear that an additional important mechanism of gene regulation occurs at the next stage of translating the messenger RNA (mRNA) into protein. (New England Journal of Medicine)

    Scientists Determine Dynamics Of HIV Transmission In UK Heterosexuals  Oct 6, 2009
    The authors note the importance to their work of the UK HIV Drug Resistance Database, which contains viral DNA sequence information from over 30,000 infected individuals. Using this database, the researchers discovered that transmission clusters in the heterosexual population were smaller than those found among HIV-infected homosexual men and that transmission was also much slower. (Science Daily)

    Outspoken Australian scientist dropped by Bush wins Nobel  Oct 6, 2009
    Professor Blackburn won with her long-time US collaborators Jack Szostak, who worked on the telemores unique DNA sequence, and Carol Greider, who co-identified the telomerase. Australia's 11th Nobel laureate, Professor Blackburn is a vocal advocate of independent scientific thought who fell out with the Bush administration over cloning and stem cells. (Sydney Morning Herald -- World)

    With Map Of Potato Genome, Scientists Hope To Improve Crop Yield  Sep 26, 2009
    Known as the SolCAP project, the research aims to use emerging DNA sequence knowledge with basic research data to improve tomato and potato varieties. "The timing of the release of the potato draft sequence is nice for the SolCAP project," Douches said. (Science Daily)

    Mutations Make Evolution Irreversible  Sep 24, 2009
    So they resurrected the GR as it existed soon after cortisol specificity first evolved -- in the common ancestor of humans and all other vertebrates with bones -- and then reversed the seven key mutations by manipulating its DNA sequence. We expected to get a promiscuous receptor just like the GR's ancestor, but instead we got a completely dead, non-functional protein," Thornton said. "Apparently other mutations that occurred during early GR evolution acted as a sort of evolutionary ratchet,... (Science Daily)

    Genome Sequencing Reveals Genetic Diversity Of Bacteria That Cause Buruli Ulcer  Sep 17, 2009
    SNPs are DNA sequence variations occurring when point mutations persist in a population. Buruli ulcer is a necrotizing skin disease that affects mostly children and youth in West Africa, but is also found in Asia, the Western Pacific, and Latin America. (Science Daily)

    ZifBASE: a database of zinc finger proteins and associated resources  Sep 9, 2009
    There is a need to develop a computational resource of zinc finger proteins (ZFP) to identify the potential binding sites and its location, which reduce the time of in vivo task, and overcome the difficulties in selecting the specific type of zinc finger protein and the target site in the DNA sequence. Description: ZifBASE provides an extensive collection of various natural and engineered ZFP. It uses standard names and a genetic and structural classification scheme to present data retrieved... (BioMed Central)

    Early 20th Century Evolutionist May Have Discovered Epigenetics  Sep 4, 2009
    Now Dr. Alexander Vargas, from the University of Chile, has re-examined Kammerer's experiments finding remarkable resemblances to newly discovered aspects of epigenetics, a flourishing new field of science which studies influences in inheritance beyond the DNA sequence. "Today Kammerer's scientific legacy is non-existent and he is often cited as an example of scientific fraud," said Vargas. (Science Daily)

    The Hawaiian algal database: a laboratory LIMS and online resource for biodiversity data  Sep 4, 2009
    The Hawaiian Algal Database was designed to showcase specimens collected from the Hawaiian Archipelago, enabling users around the world to compare their specimens with our photographs and DNA sequence data, and to provide lab personnel with an organizational tool for storing various biodiversity data types ... We describe the Hawaiian Algal Database, a comprehensive and searchable database containing photographs and micrographs, geo-referenced collecting information, taxonomic checklists and... (BioMed Central)

    * Researchers find Han obesity link  Aug 22, 2009
    According to Pan Wen-harn ([), a researcher with the Institute of Biomedical Sciences at Academia Sinica, severe obesity is associated with novel single nucleotide polymorphisms, or DNA sequence variations, of the ESR1 and PPAR loci in ethnic Chinese. Pan said that many loci associated with obesity have been reported, with at least 18 genes having been replicated in five studies on -obesity-related indicators and that 14 additional genes have been associated with obesity in Asians. (Taipei Times, Taiwan -- World)

    At the fungal farmer's market, only the best cyanobacteria are for sale  Aug 22, 2009
    Lcking and his colleagues used DNA sequence data to reconstruct evolutionary relationships among free-living members of Scytonema and putative Scytonema photobionts associated with three major fungal lineages. They discovered that these lichenized photobionts are not members of the genus Scytonema, but form a novel, previously unrecognized, entirely lichenized, lineage of cyanobacteria. (EurekAlert!)

    NIH-funded researchers sequence exomes of 12 people  Aug 17, 2009
    In a pioneering effort that generated massive amounts of DNA sequence data from 12 people, a team supported by the National Institutes of Health (NIH) has demonstrated the feasibility and value of a new strategy for identifying relatively rare genetic variants that may cause or contribute to disease ... Altogether, the project determined 300 million bases of DNA sequence the largest data set reported so far of human coding sequence produced by more advanced second-generation sequencing... (EurekAlert!)

    How I'm Spending My Summer: A GoRedFoxes.com Summer Series -- Updated Aug. 14  Aug 15, 2009
    Epigentics is the study of the processes by which a heritable phenotype that is not strictly dependent on DNA sequence is produced. Epigenetics can be studied among organisms or single cells. (Goredfoxes.com)

    Mary Had A Lot Of Lambs: Researchers Identify Way To Accelerate Sheep Breeding  Aug 11, 2009
    The change in the DNA sequence of the M allele does not change the amino acid sequence of the protein. This means that it may be an accurate indicator for the phenotype of breeding out of season, though it's uncertain whether the gene actually impacts how the sheep's body reacts to melatonin. (Science Daily)

    Ovarian Cancer Tests 'Woefully Ineffective' According To Researchers  Aug 4, 2009
    Based on the current research, Brown is also pursuing the Holy Grail of a truly cancer-specific molecular marker a novel protein or DNA sequence that occurs only in cancer cells. Many current cancer-screening tests rely on changes in levels of particular markers that also occur, albeit at lower levels, on non-cancerous cells. (Science Daily)

    Epigenetic Signature Changes In Low Oxygen Levels May Contribute To Prostate Cancer Development  Aug 3, 2009
    Epigenetic gene regulation refers to changes in gene expression caused by mechanisms other than changes in the underlying DNA sequence. The group found significant epigenetic and cellular alterations in prostate cells as a result of hypoxia. (Science Daily)

    * Taiwanese team discover immune tolerance process  Jul 18, 2009
    Transgenic means having genetic material in cells, that includes a gene or DNA sequence, transferred by means of genetic engineering from a genetically unlike organism. On the contrary, deficiency of Deltex1 increases T cell activation, and leads to resistance to anergy induction, enhanced autoantibody generation and increased inflammation. (Taipei Times, Taiwan -- World Business)

    On Malaria Struggle, Baboons And Humans Have Similar Stories To Tell  Jul 12, 2009
    In search of a genetic basis for differences in the baboons' vulnerability to infection, the researchers zeroed in on the DNA sequence surrounding the DARC gene, the same region that has been traced to malaria protection among people ... Comparison of the Amboseli baboon sequences to two other populations also showed that the DNA sequence has undergone a relatively rapid rate of evolutionary change, the mark of natural selection for malaria resistance. (Science Daily)

    Birth Weight Appears Associated with Leukemia  Jul 4, 2009
    For example, leukemia risk may be affected by epigenetic factors, modifications to genes other than changes in the DNA sequence itself. Epigenetic modifications may include the addition of molecules, like methyl groups, to the DNA backbone and other factors that may indirectly influence the expression of the genome. (MEDLINEplus)

    New Test Can Detect Both Genetic And Chromosomal Abnormalities In Embryos  Jul 2, 2009
    Unlike other methods, this is achieved entirely by analysing the DNA sequence at over 300,000 locations genome-wide in parents and appropriate family members, often children already affected by a disease, and comparing their sequence with that inherited by the embryo. This can be achieved very rapidly using current microchip technology known as microarray. (Science Daily)

    Sangamo BioSciences Announces Achievement of Key Milestone in Cell Engineering Agreement With Genentech  Jun 29, 2009
    By engineering ZFPs that recognize a specific DNA sequence Sangamo has created ZFP transcription factors (ZFP TF(TM)) that can control gene expression and, consequently, cell function. Sangamo is also developing sequence-specific ZFP Nucleases (ZFN(TM)) for gene modification. (PR Newswire)

    Melon research sweetened with DNA sequence  Jun 27, 2009
    Scientists from France and Spain already had completed partial maps of segments of the melon DNA sequence. The Texas researchers connected those segments with new findings in their study to complete the entire melon genome map. (EurekAlert!)

    New Piece Found In The Puzzle Of Epigenetics: Mechanism Of Fine Regulation Of RNA Synthesis Elucidated  Jun 26, 2009
    For many years scientists have known that the numerous biological functions of an organism are not regulated solely by the DNA sequence of its genes: Superordinate regulatory mechanisms exist that contribute to determining the fate of genes. Although they are not anchored in the DNA, they can even be passed on to subsequent generations to a certain extent. (Science Daily)

    Genetic Markers To Help Fight Diabetes Discovered  Jun 25, 2009
    To identify other variants that predict response to TZDs, TGen researchers performed a genome-wide analysis of 115,352 single nucleotide polymorphisms, or SNPs (a DNA sequence variation within the more than 3 billion base pairs in the human genome). In addition, the scientists also systematically screened 28 key genes involved in TZD metabolism or PPARG-stimulated pathways. (Science Daily)

    Domestication of Capsicum annuum chile pepper provides insights into crop origin and evolution  Jun 20, 2009
    To answer these questions, Dr. Kim and his team examined DNA sequence variation and patterns at three nuclear loci in a broad selection of semiwild and domesticated individuals ... Geographical separation among cultivated populations was reflected in DNA sequence variation. (EurekAlert!)

    Closing The Gaps In The Human Genome  Jun 16, 2009
    (May 27, 2008) Geneticists have, for the first time, determined the DNA sequence of a woman. She is also the first European whose DNA sequence has been determined. (Science Daily)

    GET ANSWERS: School Bus Video  Jun 2, 2009
    That includes social security numbers, finger prints or DNA sequence along with other things. But according to the US Department of Education, images of students captured on security tapes that are maintained by the school's law enforcement unit are not considered education records under FERPA. So, those videotapes can be shared with parents of students who are in the video and with outside law enforcement. (13WMAZ.com, GA)

    Small RNAs Yield Great Amounts Of Data From Ocean Microbe Samples  May 16, 2009
    ScienceDaily (May 15, 2009) An ingenious new method of obtaining marine microbe samples while preserving the microbes' natural gene expression has yielded an unexpected boon: the presence of many varieties of small RNAs snippets of RNA that act as switches to regulate gene expression in these single-celled creatures. Before now, small RNA could only be studied in lab-cultured microorganisms; the discovery of its presence in a natural setting may make it possible finally to learn on a broad scale... (Science Daily)

    Gene Responsible For Acetaminophen-induced Liver Injury Identified  May 12, 2009
    They found that a single letter change to the DNA sequence in one of these candidate genes, called CD44, is significantly associated with elevated serum ALT in these patients. While the role of this gene in liver toxicity is not yet known, CD44 could serve as a potentially useful marker to identify people at risk for acetaminophen-induced liver damage. (Science Daily)

    Whole Genome Sequencing Approach For Mutation Discovery  May 7, 2009
    The team mapped a fruit-fly mutation caused by the compound ethyl methanesulfonate (EMS) by determining the DNA sequence of the mutant fly s genome. The results provide insight into the mechanism of EMS mutageneseis and into gene conversion events involving balancer chromosomes genetic tools used to prevent genetic recombination between homologous chromosomes during meiosis. (Science Daily)

    * CDC unveils faster swine flu test  May 2, 2009
    Shih said that the Department of Health (DOH) acquired the key DNA sequence of the new virus strain on April 25 from the US Centers for Disease Control and Prevention and two days later obtained the RNA of the virus from the Miaoli-based Animal Technology Institute of Taiwan. Using this information, the DOH was able to develop and produce the quick-test kit, which will be distributed for use by the government and some laboratories, Shih said. (Taipei Times, Taiwan -- Business)

    News Briefs | Apr. 27  Apr 28, 2009
    His team completed the DNA sequence for the tiny worm known as C. elegans research which eventually led to the Human Genome Project. Patty Jo Watson is the Edward Mallinckrodt Distinguished University Professor of Anthropology Emerita in the College of Arts & Sciences. (Washington University Student Life, MO)

    Scientists Develop Method For Comprehensive Proteome Analysis  Apr 16, 2009
    Analysis of the proteome of an organism tells us so much more than simple DNA sequence analysis, said Dr. Wolf. Proteome analysis gives us a snapshot of what proteins are being expressed in the cell at any given point in time. (Science Daily)

    New Clues Discovered About Divergent Origin Of Sudden Oak Death Pathogen  Apr 7, 2009
    But Grunwald and his team, after years of extensive analysis of DNA sequence data, found that the three lineages are between 1. 5 million and 5. (Science Daily)

    Major aspergillus genomics supplement published by journal Fungal Genetics and Biology  Apr 3, 2009
    In 2007, DSM published a paper in "Nature Biotechnology" announcing the release of the DNA sequence of A. niger. The genome was the result of a major project in which DSM scientists worked together with some thirty research partners across the world. (EurekAlert! -- Business News)

    Sex Workers Prefer Remote Screening For Sexually Transmitted Diseases  Apr 1, 2009
    The samples were processed in the laboratory using a method called PCR (Polymerase Chain Reaction) which rapidly detects a unique DNA sequence in three of the micro-organisms that cause STIs - gonorrhoea, Chlamydia and Trichomonas. For comparison, samples were also collected and screened for these pathogens using traditional laboratory methods. (Science Daily)

    Genetic abnormality may increase risk of blood disorders  Mar 16, 2009
    The investigators carried out a genome-wide study to identify inherited DNA sequence changes that frequently occur in patients with myeloproliferative neoplasms, in which several types of blood cells are excessively produced in the bone marrow ... According to the research, these mutations do not arise randomly, but are specifically determined by the DNA sequence. (EurekAlert!)

    Monsanto cuts all jobs on Kauai  Mar 14, 2009
    Genetic engineering forces a gene from another species into the DNA sequence of a plant or animal, with the aim of giving the host organism a new trait. In crops, the inbred traits sought are often disease or insect resistance, or tolerance for herbicides or pesticides. (Honolulu Advertiser)

    Smokers' COPD Risk Is Genetic  Mar 14, 2009
    The researchers found five single nucleotide polymorphisms (SNPs) human DNA sequence variations - in ADAM33 that were more frequent in the COPD group than in the group of smokers without COPD. One SNP, known as S1, had a particularly strong link to lung abnormalities. "Functional studies will be needed to evaluate the biologic significance of these polymorphisms in the pathogenesis of COPD," according to the authors. (Science Daily)

    'The Extinction Gene': World-Changing Scientific Discovery Caught-Up in Battle Between New-Age Mongol Warlord and Russian Efforts to Dominate Europe in Unique New Thriller  Mar 14, 2009
    CANYON, Texas, March 13 /PRNewswire/ -- Walter Perriman returns home to New York from a dig he has been exploring in the Gobi Desert with evidence that 60 million years ago, global warming triggered a DNA sequence in dinosaurs that caused their extinction. He has found the same DNA sequence in recently extinct species and believes that today's climate changes are again activating what he calls the "extinction gene." The proof for his theories is in danger of being lost due to the construction of... (Yahoo! Wire -- Entertainment News)

    Genes key to smokers' lung disease  Mar 13, 2009
    The new study is unique in comparing long-term smokers with COPD versus a control group of long-term smokers without COPD. And researchers found five single nucleotide polymorphisms (SNPs) - human DNA sequence variations - in ADAM33 that were more frequent in the COPD group than in the group of smokers without COPD. One SNP, known as S1, had a particularly strong link to lung abnormalities. "Functional studies will be needed to evaluate the biologic significance of these polymorphisms in the... (India Times, India)

    A Tn5051-like mer-containing transposon identified in a heavy metal tolerant strain Achromobacter sp. AO22  Mar 8, 2009
    Other articles by authors. Related articles/pages. (BioMed Central)

    Resistance gene stops rust in wheat  Feb 20, 2009
    Spielmeyer and colleagues identified a marker - a unique DNA sequence - for the Lr34 gene. He says this will be useful in rapidly identifying the gene in a range of wheat varieties. (ABC Science Online)

    New Sequencing Technology Pinpoint 'On-off Switches' In Genomes  Feb 17, 2009
    The strategy promises to clarify the longstanding mystery of the role played by vast stretches of DNA sequence that do not code for the functional units genes that nevertheless may have a powerful regulatory influence. See also. (Science Daily)

    Science intends to tag all life  Feb 16, 2009
    "We have discovered that it is quite possible to have a short DNA sequence that can characterise just about every form of life on the planet.". Opening up. (BBC News -- Science)

    SARS spurs China to act on AIDS  Feb 14, 2009
    The DNA sequence will allow scientists to examine Neanderthals' relationship with modern humans as never before. NEWS: 11:24 12 February 2009 30 comments. (Yahoo News -- SARS)

    Test Reveals Genetic Defect That Causes Infertility In Pigs  Feb 14, 2009
    Sequence analysis of the candidate gene KPL2 revealed the presence of an inserted retrotransposon, a DNA sequence which moves around independently in the host genome. These transposable elements are found in all plants and animals. (Science Daily)

    Uranium Poisoning Treatment Developed  Feb 14, 2009
    When NikR is loaded with nickel ions, it binds to a special DNA sequence. This represses transcription of the neighboring genes, which code for proteins involved in nickel uptake. (Science Daily)

    Next gen sequencing technology pinpoint 'on-off switches' in genomes  Feb 13, 2009
    The strategy promises to clarify the longstanding mystery of the role played by vast stretches of DNA sequence that do not code for the functional unitsgenesthat nevertheless may have a powerful regulatory influence. The research is described in the 12 February edition of the journal Nature. (EurekAlert!)

    On the origin of Darwin  Feb 12, 2009
    When he was done collecting the insects, he brought them back to a BYU lab, where he studied their DNA sequence. "When you're (in Papua New Guinea) doing the field work, it's truly remarkable," Whiting said. (Pocatello Idaho State Journal, ID)

    Ancestral genome of present-day African great apes & humans had burst of DNA sequence duplication  Feb 12, 2009
    Ancestral genome of present-day African great apes s had burst of DNA sequence duplication ... Ancestral genome of present-day African great apes s had burst of DNA sequence duplication. (EurekAlert!)

    Rot's Unique Wood Degrading Machinery To Be Harnessed For Better Biofuels Production  Feb 10, 2009
    DNA sequence is the first step in the central dogma of molecular biology first articulated over 50 years ago by Francis Crick the transfer of information from DNA to RNA, which in turn, is translated into protein products, such as enzymes. Postia's genome sequence was also the first step in the process that the scientific team employed to home in on the subset of data, the transcriptome, that encodes the specific enzyme activity, and the secretome, the products exported from the cell. (Science Daily)

    International study identifies gene variants associated with early heart attack  Feb 8, 2009
    "For several decades, it has been known that the risk for heart attack the leading cause of death and disability in the U.S. clusters in families and that some of this familial clustering is due to differences in DNA sequence," says Sekar Kathiresan, MD, director of Preventive Cardiology at Massachusetts General Hospital (MGH) and corresponding author of the Nature Genetics report. "We set out to find specific, single-letter differences in the genome, what are called single-nucleotide... (EurekAlert!)

    Vitamin D helps control MS gene  Feb 7, 2009
    The researchers found that proteins activated by vitamin D in the body bind to a particular DNA sequence next to the gene, altering its function. They believe that vitamin D deficiency in mothers or even in a previous generation may lead to altered expression of the gene in their offspring. (BBC News -- Health)

    Gene's Role In Severity Of Drinking Uncovered  Feb 7, 2009
    The study, published in the February 2009 issue of Alcoholism: Clinical & Experimental Research, analyzed the associations between six different DNA sequence variations, or single nucleotide polymorphisms, of the serotonin transporter gene with the levels of drinking intensity among 275 alcohol-dependent individuals seeking treatment. Drinking intensity is measured by the amount a person consumes each day he or she drinks. (Science Daily)


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