Bazell: How safe are the shots? Oct 6, 2009
There is initial testing of safety and efficacy thats done in a few hundred people. By necessity you cant do it in thousands and thousands of people. (MSNBC -- Health)
Click to read:Health Workers Protest Flu Vaccine Mandate Oct 5, 2009
A regular flu shot is one thing but this new vaccine just does not have enough data to suggest safety efficacy is what I would like to see. I'm for the healthcare workers on this one. (CBS News)
Concerned about health care reform Oct 4, 2009
Patient care should be based on either demonstrated evidence of or expert consensus on safety, efficacy and effectiveness. In other words, physicians should care for patients in ways that are proven or generally agreed to be safe, effective and efficient. (Carlisle Sentinel, PA)
UMASS AND FALLON: Mammogram reminder system studied Oct 3, 2009
The study of 23,000 female Fallon Community Health Plan members age 51 to 84 who also have Fallon Clinic doctors will look at the costs and efficacy of setting up a complex reminder system. The first round this year will involve about 6,000 Fallon members, according to Yood. (Winchester Star, MA, MA)
Arena weight-loss trial disappoints investors Sep 26, 2009
"Lorcaserin's efficacy was once again underwhelming, even worse than the prior ... trial," JP Morgan analyst Cory Kasimov said in a research note ... "We met the second of those two alternate efficacy end points," said Arena Chief Executive Jack Lief ... Arena's efficacy results have fallen somewhat short of those posted by its rivals, but CEO Lief said lorcaserin's benign side effect profile is a major benefit. (Yahoo News -- Pharmaceutical Industry News)
Vectibix(R) in Combination With Chemotherapy Significantly Improves Progression-Free Survival in First-Line Metastatic Colorectal Cancer Sep 24, 2009
Patients enrolled in the '203' or PRIME trial (Panitumumab Randomized trial In combination with chemotherapy for Metastatic colorectal cancer to determine Efficacy) were randomized to receive either 6. 0 mg/kg of Vectibix and FOLFOX4 once every two weeks (Q2W) or FOLFOX4 alone Q2W. The primary endpoint of the study is progression-free survival by KRAS status and secondary endpoints include overall survival, objective response rate, time to progression, duration of response and safety. (PR Newswire)
REPEAT: 'Project Runway' Designer in New Orleans to Educate About Living with HIV and Combat Stigma Associated with the Disease through Living Positive By Design Sep 21, 2009
"Given all the treatment options that are available today, it is important that both the efficacy and tolerability of treatments be considered when choosing a regimen.". In 2008, Jack held Living Positive By Design events in Miami/Fort Lauderdale, Florida, at the 2008 United States Conference on AIDS (USCA); in Atlanta, Georgia, at the Atlanta AIDS Walk; and in New York, New York, at the Gay Men's Health Crisis' (GMHC) annual Fashion Forward fundraiser. (Yahoo! Wire -- Entertainment News)
Phase 3 Trial Shows Denosumab Delayed Skeletal Related Events in Advanced Cancer Patients With Bone Metastases Sep 21, 2009
THOUSAND OAKS, Calif. There is no need for renal monitoring or dose adjustments due to renal impairment," said David Henry, M.D., clinical professor of Medicine, Pennsylvania Hospital, Philadelphia, PA, United States of America. "Furthermore, the positive results of this study, combined with the convenience of a monthly subcutaneous injection and without the flu-like symptoms associated with Zometa administration, make this an exciting potential treatment option for advanced cancer patients. (Canada Newswire)
Small change: Does ‘microlending’ actually fight poverty? Sep 20, 2009
Yet, despite the explosive growth, there s been little rigorous research on the efficacy of microcredit. This is not necessarily unusual for development and antipoverty interventions. (Boston Globe)
Obama replaces God in schools Sep 17, 2009
Deists did not believe in the virgin birth, divinity, or resurrection of Jesus, the efficacy of prayer, the miracles of the Bible, or even the divine inspiration of the Bible. Get over the Christianity myth. (Logan Herald Journal, UT)
FDA panel wants more data on Genzyme cancer drug Sep 14, 2009
WASHINGTON A panel of cancer experts has issued a negative review of a leukemia drug from Genzyme, saying more data is needed to establish its safety and efficacy for older patients. The Food and Drug Administration's oncology panel voted 9-3 Tuesday that Cambridge, Mass. (Yahoo News -- Pharmaceutical Industry News)
Clinical trials disappoint Array BioPharma Sep 6, 2009
While we are disappointed in the overall efficacy outcome, we were pleased with the confirmation of the favorable safety profile and are continuing to evaluate the regional results. Array BioPharma plans to start separate tests of ARRY-162 as a cancer treatment. (Denver Business Journal, CO)
Companies claim single-dose swine flu vaccine Sep 5, 2009
Search Type Choose a search type from the items below. Most Blogged - Health. (Yahoo News -- Top Stories)
"Death Panels" Born in Heartland Hospital Sep 5, 2009
The legislation lists the mandatory benefits a plan must include to be qualified, including prescription drugs, mental health and substance use disorder services, preventive wellness services, maternity care and other coverage, regardless of if they are needed or desired by the patients or of their efficacy and cost effectiveness. It sets essential minimum benefits at 70% of actuarial value, making high-deductible plans or traditional insurance. (CBS News)
A $2.3 billion fine? Thats hitting a mule with a 24 Sep 3, 2009
It s impossible for anyone including a doctor to guess until you try a particular drug how it s going to do with a particular patient in terms of efficacy and side effects ... When you launch an antidepressant, none of them are cheap, and for many of them it takes an average of a minimum of 10-12 days to 3 weeks to know if they have efficacy. (Atlanta Journal-Constitution -- Opinion)
Getting Real About Health Care Reform Sep 1, 2009
To test the plans efficacy, three or more states could implement these respective plans on a state level. The federal government would underwrite all net costs for the participating states to implement the plans on a trial demonstration basis for at least four years. (Townhall.com)
Doctors urge delay on vaccine Aug 29, 2009
Professor Bishop said safety and efficacy data from vaccine trials was still coming in, but so far it looked similar to any other seasonal flu vaccine. We would expect some more definite data over the next few weeks. (Sydney Morning Herald -- Australia)
Obama's reality problem Aug 26, 2009
Obama s personal popularity did not translate into a belief in the efficacy and integrity of government, Galston said. Add to this the fact that one of the main sources of revenue to fund Obamacare is reductions in Medicare. (Orangeburg Times and Democrat, SC)
Will this really resolve the issue? Aug 25, 2009
"There's where you're are wrong. It does propose less healtcare, specifically all that unnecessary healthcare. That's what the Advisory board is all about; reviewing efficacy and putting a stop to all this fruitless surgery, therapies, and drugs that do nothing but help the doctor rack-up a bigger bill and, thus, a bigger pay check. I guess a provider, such as yourself, would be reluctant to acknowledge that reality ". Rebecca wrote on Aug 24, 2009 9:11 AM:" Good letter. No one would argue that... (Bismarck Tribune, ND)
Class Certification Denied in Fraud Suit Over Marketing of Relacore Aug 19, 2009
Those factors included the reason for buying Relacor, which advertisements induced the purchase, whether buyers were influenced by a personal recommendation, how the buyers' underlying health might have affected the product's efficacy, how much they paid and whether they sought or obtained a refund. She identified additional issues on the other claims, such as whether class members received any benefit, on the unjust enrichment claim, and whether timely notice to the seller was provided, on the... (Law.com)
Vectibix(R) Significantly Improved Progression-Free Survival in Second-Line Treatment of KRAS Wild-Type Metastatic Colorectal Cancer Aug 18, 2009
Detailed efficacy and safety data from both studies will be presented at Europe's largest cancer conference, ECCO 15 - ESMO 34, in September 2009. Study Design. (PR Newswire)
Read 'Cost of Freedom' recap Aug 18, 2009
Dagen McDowell, FOX Business Network: Collecting data for the efficacy of health care treatments isn't 00001B5C necessarily a bad thing. The problem isn't the collection of the information. (Fox News)
Amgen Issues Statement on Outcomes of Advisory Committee for Reproductive Health Drugs (ACRHD) Meeting Aug 14, 2009
After reviewing safety and efficacy data from 30 clinical studies involving more than 12,000 patients, the Committee recommended approval of Prolia for the treatment of postmenopausal osteoporosis and for the treatment of bone loss in patients undergoing hormone ablation for prostate cancer. The Committee recommended against approval of Prolia to treat or prevent bone loss in women with breast cancer undergoing hormone ablation until additional data are available. (PR Newswire)
Auxilio, Inc. Announces Appointment of New President and CEO Aug 12, 2009
Such forward-looking statements involve known and unknown risks and uncertainties, including uncertainties relating to product development, efficacy and safety, regulatory actions or delays, the ability to obtain or maintain patent or other proprietary intellectual property protection, market acceptance, physician acceptance, third party reimbursement, future capital requirements, competition in general and other factors that may cause actual results to be materially different from those... (Primezone Releases)
Allon Therapeutics Releases Second Quarter Operating Results Aug 11, 2009
"We anticipate that prospective pharmaceutical partners will see this new schizophrenia data as complementary to the human efficacy data they've already seen from aMCI. We continue to work toward the completion of a partnership, and we anticipate that it will only advance once we're in a position to share the imaging data with prospective partners." ... Allon's drug davunetide has demonstrated human efficacy in amnestic mild cognitive impairment, a precursor to Alzheimer's disease, and... (CCNMatthews Press Releases)
Bannock's levy rate to rise Aug 10, 2009
Huh wrote on Aug 7, 2009 4:55 PM:" Thank you for responding as though I were 7 yrs old, and have no idea about why this is taking place.No doubt you are also aware that robins and crows, amongst other animals, carry and spread the virus....shall we proceed to a bird abatement program next?Furthermore, I'm sure you're aware that while 80% of people never experience any symptoms of any kind, the vast majority of the remainder experience nothing more than flu-like symptoms. There are any number of... (Pocatello Idaho State Journal, ID)
Does the Pot Pill Work? Aug 5, 2009
" Research into the effects of medical marijuana is ongoing: The University of California, San Diego, for example, boasts a engaged in "focused controlled clinical trials on the efficacy of cannabis in patients diagnosed with HIV/AIDS, cancer, seizures or muscle spasms associated with a chronic debilitating condition, or any other serious condition providing sufficient theoretical justification. " (The director of the UCSD program, Dr. Igor Grant, was out of the country and could not be reached... (CBS News -- US)
Read the story Aug 4, 2009
(10% reduction is clinically significant and proof of efficacy), is phenominal. These tests are administered independent of Dr. Harch Eighty-percent of those treated have been able to return to work, duty, or school, and 100% have had improvement. (CBS News -- Evening News)
How Do We Know Health Care Reform Will Cost $1 Trillion? Jul 31, 2009
There are also many basic questions about the efficacy of certain programs on which the data are unsettled. For example, does offering long-term homes for the chronically ill save money. (Slate)
BIDEN: ANOTHER DAY OF CLOSED, SECRET MEETINGS... Jul 30, 2009
Biden's numbers are tied closely to Americans' belief in the economic efficacy of President Obama's stimulus package. Those who think it'll work, like him; those who don't, don't. (The Drudge Report)
The Best Birth Control Jul 30, 2009
And while efficacy studies suggest that the pill, patch, or ring are 99 percent effective in a clinical setting, real-life compliancylike forgetting to take the pill at the same time every dayreduces its success rate ... Check out the comments regarding this article about the efficacy of the "withdrawal method" that was. (Slate)
Economist: Look for tax hikes Jul 27, 2009
What's your assessment of the efficacy of the first. A: You never can tell. (Waterloo Courier, IO)
Our View: True health care change is in proposal’s details Jul 25, 2009
The merits and efficacy of new bureaucratic layers should be debated seriously and weighed carefully against their cost. There s another hammer that the feds plan to wield to likewise compel individuals to sign up for a plan. (Atlanta Journal-Constitution -- Opinion)
Senators seek coverage for alternative therapies Jul 24, 2009
But the American Medical Association says there is little evidence to confirm the safety or efficacy of most alternative practices. Much of the information currently known about these therapies makes it clear that many have not been shown to be efficacious, the association said in a policy statement. (Boston Globe)
Experts dispute doctor's stem cell breakthrough claim Jul 15, 2009
"I have looked for the scientific efficacy of this approach, and can find none," Edelman said. Health Library. (CNN -- Health)
Obama's diplomacy to be tested in Russia Jul 6, 2009
Obama's administration is reviewing the efficacy of plan, which Bush had pushed hard. U.S. leaders have expressed hope of getting Russian cooperation on missile defense. (San Francisco Chronicle -- Politics)
Obama Defends Cost of Agenda Jun 25, 2009
Republicans regularly question the efficacy of the stimulus passed earlier this year and the Democrats overall approach on spending. Republicans in recent days have released a flood of statements like a June 17 release by Senate Minority Leader Mitch McConnell (Ky. (Roll Call)
Marijuana bill restrictions Jun 24, 2009
Some of the most rigorous studies establishing the safety and efficacy of medical marijuana in pain management have been done. These studies used the gold standard of scientific research: the double-blind, placebo-controlled clinical trial. (NJ.com -- Times)
Photo by Ellen Sussman | Special to the Green Valley News Dr. Joanne Jeter speaks to two breast cancer survivors during a break Saturday at the Arizona Cancer Center. Jun 24, 2009
To test the efficacy of a new drug some patients may be referred to take part in a clinical trial, which are held at Comprehensive Cancer Clinics such as the Arizona Cancer Center. Swart said most clinical trials do not use placebos, and patients chosen to participate should be comfortable with their doctor and should ask a lot of questions. (Green Valley News & Sun, AZ)
Federal regulatory burden hits $1.17 trillion Jun 20, 2009
All better requires is EFFICACY to be BETTER not MORE.. Michael H. Smith. (Atlanta Journal-Constitution -- Opinion)
Oh, goodness. Politicians are about to ‘fix’ health care. Jun 18, 2009
Having government make rules about efficacy and availability of care smacks of Big Brother, but those kind of difficult and painful choices must be made if cost factors are to be included in health care decisions ... This country ranks behind several 3rd world countries in efficacy, and I think a little more I m familiar with the medical literature and what hospitals have to offer in several areas in this country and this state than Wooten. (Atlanta Journal-Constitution -- Opinion)
Study: Virtual colonoscopy an effective option Jun 18, 2009
"Computed tomographic colonography has been shown to be better accepted than colonoscopy and has a negligible risk of serious adverse events; thus, it may help increase the low adherence reported for individuals who are candidates for screening, which is the main negative factor affecting its efficacy in reducing mortality from colorectal cancer," Regge's team wrote. "With the majority of individuals in the United States who meet criteria for colorectal cancer screening and surveillance not... (MSNBC -- Health)
Decoding the health care debate a glossary Jun 18, 2009
Comparative effectivenessComparative effectiveness research examines the relative cost and efficacy of medical procedures in one hospital or region of the country contrasted with another hospital or region, in the hopes of forcing down costs in the more expensive areas. President Obama has endorsed this approach, saying the Mayo Clinic in Minnesota and other institutions offer the highest-quality care at costs well below the national norm. (MSNBC -- Health)
Health Care Co-Ops, D.C.'s Latest Buzz, Have Ups, Downs Jun 16, 2009
I purchase over $10,000 in medications that managed care will not cover despite scientific evidence of efficacy. It's time for other options, negotiation of drug prices, legal importation and regulation of pharmacies (Ambien costs. (Investors Business Daily)
What to try before HMObama Jun 16, 2009
They include better use of information technology in health care, with the federal government setting a common platform, and wider availability to patients of data about the quality and efficacy of various treatment options, without letting bureaucrats decide which treatments are allowed. We might also try tort reform to rein in medical malpractice lawsuits and eliminate unnecessary procedures that doctors order just to reduce their legal liability. (Atlanta Journal-Constitution -- Opinion)
Numbers crunchers shape health reform Jun 16, 2009
Comparative effectiveness research examines the relative cost and efficacy of treating patients in different hospitals or regions of the country. For example, over nearly 15 years, the , a project of the Dartmouth Institute for Health Policy and Clinical Practice, found that higher per-patient spending on Medicare patients did not necessarily result in better care. (MSNBC -- Health)
Consumer Reports 'Best Buy Drug' for Enlarged Prostate Could Save Consumers Nearly $3,000 a Year Jun 16, 2009
"This drug has been on the market for decades and its safety and efficacy profile is well established," says Santa. Consumer Reports Best Buy Drugs, which rates more than 200 prescription drugs to treat more than 20 common conditions, is part of a larger initiative by the newly launched Consumer Reports Health Ratings Center to provide consumers with health Ratings based on independent and unbiased review of the best scientific evidence available, also known as Comparative Effectiveness... (PR Newswire)
Glaxo signs deal with Concert on early stage drugs Jun 6, 2009
As deuterium is heavier than hydrogen, it forms a stronger chemical bond to a carbon atom of a molecule, which may substantially improve a drug's metabolic properties, potentially resulting in better efficacy. Patrick Vallance, senior vice president of drug discovery at Glaxo said that Concert's approach to deuterium modification of medicines "has broad potential to enhance certain drug properties and result in innovative new medicines.". (Yahoo News -- Pharmaceutical Industry News)
AstraZeneca e-mails show debate on Seroquel risks Jun 4, 2009
"Going back almost 20 years, AstraZeneca has conducted 118 studies on the safety and efficacy of Seroquel," company spokesman Jewell said. AstraZeneca faces roughly 15,000 lawsuits over Seroquel, about 60 percent of them in state courts. (Yahoo News -- Pharmaceutical Industry News)
FDA Approves Reclast(R) to Prevent Osteoporosis in Postmenopausal Women With Convenient Less Frequent Dosing Jun 1, 2009
"We are very pleased that this latest US approval recognizes the large body of safety and efficacy data for Reclast and underlines its potential to protect patients with a number of bone disorders," said Trevor Mundel, MD, Global Head of Development at Novartis Pharma AG. "Women with low bone mass in the US now have an important new option that is proven to strengthen their bones, and therefore help prevent the onset of osteoporosis, for a full two years with only one infusion.". The new... (PR Newswire)
STEP AWAY FROM YOUR COMPUTER! May 31, 2009
The efficacy of our rescue depends considerably on whether the next president thinks less like Hoover and more like Roosevelt. Basically Republican assertions are that somehow, magically, the Republican ideas about recovery would have magically created a world that looks like the one we currently live in, when in fact, nothing like it existed before and there was NO sign that somehow, magically the free market capitalists would have suddenly given workers wages that would allow them to exist at... (Atlanta Journal-Constitution -- Opinion)
Compliance and cost: Bitter pills to swallow in the age of oral chemotherapy May 29, 2009
Physicians call for strategies to improve adherence to boost safety, efficacy of new drugs ... "We need to recognize the reality of non-adherence and better understand how to help our patients take their medications in the most effective way. Studies have shown that when patients don't adhere to their medication regimens, costs for their health care balloon due to more physician visits, more hospital visits, and longer stays once they're admitted. In addition, non-adherence during clinical... (EurekAlert!)
Guest opinion: Time has come for U.S. single-payer plan May 29, 2009
allow the creation of uniform, accurate data bases on costs of providing services, efficacy data on surgical and medical treatment protocols and would serve as an efficient "Early Warning System" in the event of potential epidemics ... The private insurance industry has had 60 years to prove the efficacy and viability of private health insurance in America. (Montana Standard, MT)
Supplements Can Do Good Or Cause Harm May 19, 2009
There are two problems: the full ingredient list may not be readily available or may not be written in plain English; or the science may conflict about a particular product's efficacy. Science Can Be Shell Game. (KCRA 3, CA)
T Vijay: Whose elections were these? May 16, 2009
And we shall be happy about the great vivacity, prudence and efficacy of our electorate and democratic institutions. The second day, having returned from one such serious TV discussion on a very honestly fudged exit poll, we completed the ritual of watching Balika Vadhu at home and went out for "chaat" in Fateh Puri. (India Times, India)
AstraZeneca shares leap after its drug beats Plavix in test May 15, 2009
AstraZeneca did not specify the scale of its drug's superiority in a brief statement, simply stating that Brilinta had "achieved a statistically significant primary efficacy endpoint.". The safety profile was in line with earlier Phase II studies, it added. (Yahoo News -- Pharmaceutical Industry News)
GOP scam artists take aim at health care May 15, 2009
Drugs, too, will have to prove their efficacy. Welcome to the age of generics. (Herald Online, SC -- Opinion)
Health Officials: Flu Vaccine Could Come Soon May 7, 2009
If the need arises, they can coordinate with manufacturers on clinical trials, verifying the safety, efficacy and right dosages of the vaccine, and then move to mass production. CDC has confirmed more than 640 cases in the U.S., and states are reporting at least 11 not yet on the CDC list. (Click2Houston, TX)
The Cult of Ronald Reagan, part XIV May 5, 2009
Wow that thirty year old cherry Kool Aid hasn t lost its efficacy. AmVet. (Atlanta Journal-Constitution -- Opinion)
How To Protect Against Flu Epidemic Apr 30, 2009
While surgical masks may help to prevent the spread of airborne bacteria and viruses, there is a lot of debate about the efficacy and safety of flu vaccines. One proponent of the natural prevention of disease, Zoltan Rona in Natural Alternatives to Vaccination (Alive Books; 2000) says, Outbreaks of the flu still occur despite widespread use of the recommended flu vaccine. (Suite101.com)
Governor race likely to depart from tradition Apr 28, 2009
Maybe he can use the Tamiflu that he bought for $6 million that had no efficacy against H5N1 Birdie flu and promotes resistance in that disease for the Swine Flu. It and Ralenza are the 2/4 neuraminidase inhibitors with Swine flu efficacy. (Atlanta Journal-Constitution -- Opinion)
Medical marijuana requests climb Apr 16, 2009
For example, many doctors are reluctant to authorize their patients to use marijuana either because its efficacy has not been proven in rigorous trials, shown to be superior to other drugs, or because they themselves fear risking their own federal license to prescribe medications like opiate pain killers if they are seen to be defying federal drug law. I have legitimate cancer patients who cannot get a doctor to sign, the Boulder dispensary owner said. (MSNBC -- Health)
READ THE MINUTES: FOMC meeting of March 17-18 Apr 9, 2009
Broad equity price indexes dropped significantly, on balance, over the intermeeting period amid continued concerns about the health of the financial sector, uncertainty regarding the efficacy of government support to the sector, and a further weakening of the economic outlook. Bank stock prices were particularly hard hit, and the credit default swap (CDS) spreads of many banks rose above the peaks recorded last fall on anxieties about the financial conditions of the largest banking firms. (USA Today -- Money)
Scientific abstracts -- 2009 Annual Assembly, American Academy of Hospice and Palliative Medicine Mar 28, 2009
To evaluate the efficacy of a documentary film about family caregiving to improve clinician sensitivity to the needs of family caregivers. III. Methods. (EurekAlert!)
EDIT: Promises Galore Mar 26, 2009
PDS needs a thorough revamp, and the better record on meeting targets of a few southern states may give pointers on efficacy. While identification of beneficiaries is a complicated task, ration cards could be replaced with smart cards that are less open to misuse. (India Times, India)
