Screening Guidelines For Breast, Cervical And Colorectal Cancers Redefined Oct 28, 2009
genetic diagnosis of Familial Adenomatous Polyposis. genetic history of Hereditary Nonpolyposis Colorectal Cancer or a clinical history suggesting such. (Science Daily)
Cequent tkRNAi Technology to be Presented at the Centennial Meeting of the American Association for Cancer Research Apr 16, 2009
These findings open the door to clinical Highly Rated Phase I testing of Cequent's lead drug candidate Poster CEQ508, an orally administered tkRNAi therapeutic Presentation targeting the primary oncogene (beta-catenin, CTNNB1) in FAP (familial adenomatous polyposis). FAP is an inherited gastrointestinal disease that causes hundreds of polyps to form in the colon. (PR Newswire)
Genetic Data From 1630s Backs Cancer Screening Mar 26, 2009
The gene mutation causes a condition known as attenuated familial adenomatous polyposis (AFAP). AFAP causes the growth of colorectal polyps that have the potential to become cancerous. (Science Daily)
The Notch Gene Accelerates Colon Carcinogenesis Mar 25, 2009
The Wnt signalling pathway is tightly controlled by the APC (adenomatosis polyposis coli) gene which is associated with early-stage colon carcinogenesis: mutations in one of the two copies of this tumour suppressor gene underlie familial adenomatous polyposis, a condition characterised by the growth of hundreds or even thousands of polyps in the large intestine from adolescence on. This disease accounts for 1% of cases of colon cancer. (Science Daily)
NURSE’S NOTES - Colorectal cancer deadly, but preventable Mar 25, 2009
An example of this would be familial adenomatous polyposis, or FAP. People with the classic type of FAP may begin to develop multiple polyps in the colon as early as their teenage years. Colorectal cancer and precancerous polyps don t always cause symptoms. (Missoulian, MT)
