Protein Plays Jekyll And Hyde Role In Lou Gehrig's Disease Jul 31, 2008
Weissman et al. Protein Aggregation and Protein Instability Govern Familial Amyotrophic Lateral Sclerosis Patient Survival. PLoS Biology, 2008; 6 (7): e170 DOI. (Science Daily)
New Insight Into Cause Of Lou Gehrig's Disease May 30, 2007
The findings are presented in the article "Interaction between Familial Amyotrophic Lateral Sclerosis (ALS)-linked SOD1 Mutants and the Dynein Complex.". Note: This story has been adapted from a news release issued by University of Kentucky. (Science Daily)
News Tips from The Journal of Neuroscience Apr 18, 2006
CuZn superoxide dismutase (SOD1)mutations underlie some cases of familial amyotrophic lateral sclerosis (ALS) ... CuZn superoxide dismutase (SOD1)mutations underlie some cases of familial amyotrophic lateral sclerosis (ALS). (EurekAlert!)
A Clue To Core Problem Of Neurodegenerative Disease And Cell Death Feb 11, 2006
But explanations for the mechanism that actually causes cell death have varied widely, puzzling scientists and leading them to ask whether Alzheimer's, Parkinson's, Huntington's and Creutzfeldt-Jakob diseases and familial amyotrophic lateral sclerosis (ALS) are related diseases or very different diseases. Northwestern University scientists now offer a clue that may get to the core of the cell death question and establish a common mechanism in these diseases. (Science Daily)