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    News and Articles on Gene

    Archives: Gene

    Scan could cut breast removal ops  Nov 22, 2009
    They found the scans were almost twice as sensitive as X-ray mammography (XRM) in detecting cancer in women under 50 at high genetic risk ... Around 2% of breast cancer is due to the recently discovered breast cancer gene mutations BRCA1 and BRCA2 ... Women with one of these gene mutations come from families where there is a strong family risk of breast cancer, and more than half of them will develop breast cancer by the age of 70. (BBC News)

    An Atomic-Level Look at an HIV Accomplice  Nov 22, 2009
    Amyloid fibers are of great interest because they are the calling cards of many neurodegenerative diseases, such as Alzheimer's and Parkinson's, and aging-related diseases like type-2 diabetes ... (July 9, 2009) Scientists have discovered that specific microRNAs (non-coding RNAs that interfere with gene expression) reduce HIV replication and infectivity in human T-cells. (Science Daily)

    Why Can't Some People Give Up Cocaine?  Nov 22, 2009
    23, 2009) A new study in rats has found that N-acetylcysteine (NAC), a commonly available and generally nontoxic amino acid derivative, reverses changes in the brain's circuitry associated with cocaine ... The first in a new generation of gene microarrays, computer chips that chemically or electrically express DNA, can predict how a person's body will. (Science Daily)

    Mixed results on charter schools in Arizona’s wide-open education market  Nov 22, 2009
    An Arizona State University education professor, Gene Glass, said he could show a visitor exciting stuff in at least 50 regular public schools. Through test scores, Arizona rates about 24 percent of charter schools as excelling or highly performing. (Boston Globe)

    New Cancer Guidelines Say to Start Mammograms at 50, Not 40  Nov 22, 2009
    The guidelines are for the general population, not those at high risk of breast cancer because of family history or gene mutations that would justify having mammograms sooner or more often. The new advice says. (Fox News)

    Schizophrenia Gene's Role May Be Broader, More Potent, Than Thought  Nov 22, 2009
    21, 2009) UCSF scientists studying nerve cells in fruit flies have uncovered a new function for a gene whose human equivalent may play a critical role in schizophrenia ... Scientists have known that the mutated form of the human gene -- one of three consistently associated with schizophrenia -- mildly disrupts the transmission of chemical signals between nerve cells in the brain ... The new study focuses on genes involved in "adaptive plasticity," the capacity of nerve cells to compensate for a... (Science Daily)

    Garden built in teacher's honor rededicated  Nov 21, 2009
    Those wanting to contribute to the Linda Gail Hendrick Scholarship Fund can make a check out to the fund and mail it to either Gene Spires or Eleanor Hopson, 864 Broad St., Augusta, GA 30901. TIMELINE. (The Augusta Chronicle)

    Ancestry Attracts, but Love Is Blind  Nov 21, 2009
    Research, published in BioMed Central's open access journal Genome Biology, shows that Mexicans mate according to proportions of Native American to European ancestry, while Puerto Ricans are more likely to settle down with someone carrying a similar mix of African and European genes ... Neil Risch, from the University of California, San Francisco, worked with a team of researchers to study the effects of ancestry on partner choice in Mexicans and Puerto Ricans living in their own countries or in... (Science Daily)

    Need an app for that?  Nov 21, 2009
    Should your company have an iPhone app. for free extra services. (San Jose Business Journal, CA)

    Antioxidant Found in Vegetables Has Implications for Treating Cystic Fibrosis  Nov 21, 2009
    20, 2009) Scientists at the University of Pennsylvania School of Medicine discovered that a dietary antioxidant found in such vegetables as broccoli and cauliflower protects cells from damage caused by chemicals generated during the body's inflammatory response to infection and injury. The finding has implications for such inflammation-based disorders as cystic fibrosis (CF), diabetes, heart disease, and neurodegeneration ... "Dr. Lu's work throws new light on how the genetic defect underlying... (Science Daily)

    Tribe Evolves Brain Disease 'Resistance Gene'  Nov 21, 2009
    Brain disease 'resistance gene' evolves in Papua New Guinea community; could offer insights into CJD ... Brain Disease 'Resistance Gene' Evolves in Papua New Guinea Community; Could Offer Insights Into CJD ... 21, 2009) A community in Papua New Guinea that suffered a major epidemic of a CJD-like fatal brain disease called kuru has developed strong genetic resistance to the disease, according to new research by Medical Research Council (MRC) scientists. (Science Daily)

    Causative Gene of Rare Disorder Discovered by Sequencing Only Protein-Coding Regions of Genome  Nov 21, 2009
    20, 2009) For the first time, scientists have successfully used a method called exome sequencing to quickly discover a previously unknown gene responsible for a mendelian disorder ... Mendelian disorders, such as cystic fibrosis and sickle cell disease, are the result of one or more mutations in a single gene, typically a gene that makes a protein ... That is why sequencing the exome is an efficient strategy to search for genes that underlie rare genetic disorders. (Science Daily)

    Obituaries, Friday, Nov. 20, 2009  Nov 21, 2009
    Mills, Donald Eugene Gene, died Sunday. Funeral: 1 p.m. CST today, Cunningham Funeral Home, 441 Lanterman St. Burial: Bridgeport City Cemetery. (Vincennes Sun Commercial, IN)

    New Cause of Osteoporosis: Mutation in a miroRNA  Nov 21, 2009
    20, 2009) Many biological processes are controlled by small molecules known as microRNAs, which work by suppressing the expression of specific sets of genes ... These data led the authors to conclude that miR-2861 has an important role in controlling the generation of the cells responsible for bone formation and that defects in the processing of its precursor can cause osteoporosis ... (May 12, 2009) MicroRNAs are small RNA molecules of 20-25 nucleotides length, regulating gene expression by... (Science Daily)

    Military experiment seeks to predict PTSD  Nov 21, 2009
    Select Marine and Army units are undergoing a battery of physical and mental tests before deployment including genetic testing, brain imaging and stress exams ... 17: Army Vice Chief of Staff General Peter Chiarelli says, as of Monday, 140 active duty soldiers were believed to have died of self-inflicted wounds so far in 2009 ... They donated blood, urine and saliva samples so researchers can search for genetic biomarkers that might play a role. (MSNBC -- Terrorism)

    New Nanomethod Paves the Way for New Measuring Technology and Hypersensitive Sensors  Nov 21, 2009
    12, 2009) Scientists have developed a highly sensitive measuring method with which the efficiency of gene transfer in cases if cardiovascular diseases can be investigated. The researchers determine, accurate. (Science Daily)

    Examining Mathematical Abilities in Children With Fetal Alcohol Spectrum Disorder  Nov 21, 2009
    "Two of these regions in the left parietal area are very similar to previous findings in healthy children and in a rare genetic disorder, suggesting that these regions are key areas for math across diverse populations. The two other regions -- the cerebellum and the brainstem -- might be unique to children with FASD in terms of math-structure relationships." ... In the first study to link taste genes to behavior in children, researchers looked at how natural variations in a recently discovered... (Science Daily)

    Massachusetts health care providers urge revamping payment system  Nov 21, 2009
    We ve been reinvesting in the infrastructure of our organization to be ready for the moment that s about to arrive, said Gene Lindsey, chief executive of Atrius Health, a Newton-based alliance of community physicians groups that includes Harvard Vanguard Medical Associates ... The feeling was there s just too much incentive to do more volume as a way to generate revenue ... He said Partners HealthCare System, the state s largest hospital group that includes Boston s Massachusetts General... (Boston Globe)

    Help Center struggling, but blessed  Nov 21, 2009
    The number of applicants for assistance from the Bogalusa Help Center food bank has likely doubled from 3,100 families in 2006 to an estimated 6200 families in 2009, Volunteer President Gene Hayman said Thursday. We are presently giving boxes to 530 families each month, he said. (Bogalusa Daily News, LA)

    How Fish Is Cooked Affects Heart-Health Benefits of Omega-3 Fatty Acids  Nov 21, 2009
    The findings also suggest that the cardioprotective benefits vary by gender and ethnicity -- perhaps because of the preparation methods, genetic susceptibility or hormonal factors ... "Alternately, if it is verified that the interactions between fish consumption, risk factors and ethnicity are due to genetic susceptibility, the heart-disease prevention message can be personalized to ethnic groups, and future study could identify susceptibility at the genetic level." ... 25, 2009) Omega-3 fatty... (Science Daily)

    Explanation for Rapid Maturation of Neurons at Birth  Nov 21, 2009
    Researchers at Duke University Medical Center have figured out the genetic control of the pump in rodents ... Together the two suppress the gene Kcc2, which is responsible for producing proteins for the transporter molecules that "pump" out the chloride ... The researchers confirmed that increased activity of the gene resulted in lower levels of chloride in the neurons. (Science Daily)

    Solving the 50-Year-Old Puzzle of Thalidomide  Nov 21, 2009
    This model proposes that all thalidomide associated defects could be caused by the same 'common mechanism', primarily an effect on angiogenesis, the growth of new blood vessels ... The first in a new generation of gene microarrays, computer chips that chemically or electrically express DNA, can predict how a person's body will. (Science Daily)

    Hope over Down's learning problem  Nov 21, 2009
    Down syndrome is a genetic disorder caused by an extra copy of chromosome 21 ... In the latest study researchers from Stanford University and the Lucile Packard Children's Hospital - both located in Stanford, California - worked on mice genetically engineered to mimic Down's syndrome ... Unlike other mice, the genetically engineered animals, when placed in a cage with which they were unfamiliar, failed to start building new nests. (BBC News -- Health)

    Gene Ritvo, photographer and lover of antique cars, 74  Nov 21, 2009
    to Newport, R.I., Gene Ritvo was as well regarded as the vehicles he memorialized ... Gene recognized art, class, and beauty, whether it was a pretty woman, an automobile, or a toaster, said John Lawlor of East Bridgewater, technical adviser for WBUR s Car Talk ... Gene was a big guy, but appreciated things that were different and beautiful, Lawlor said. (Boston Globe)

    Reviews of Senate health bill mixed  Nov 21, 2009
    The latter provision is troubling to Gene Ransom III, executive director of state medical society MedChi. MedChi members do not want to see any health procedures taxed, Ransom said. (Baltimore Business Journal, MD)

    Illegal Use of Sandra Bullock  Nov 21, 2009
    By just reading the description in Levin's piece--and I generally like his stuff--I would probably think this film had an overdose of Sandra Bullock ... A horrible example of this is Mississippi Burning, tripe that put actual civil rights workers in the background so good old boy Gene Hackman can save the day by flirting with a sheriff's wife. (Slate)

    Cancer research is improving treatment  Nov 21, 2009
    One size does not fit all when it comes to genetic makeup ... of years of genetic research and its potential in practical ways of treating certain cancers, said James Weldon, executive director of the Mariposa Community Health Center ... Genetics research has come a long way. (Nogales International, AZ)

    Opening the Screening Door  Nov 21, 2009
    It hooks up people's general view that medical advice is always shifting and unknowable, which is merely irritating, and turns it into a government-fueled plot to deny them health and, ultimately, their lives ... Interviewer is former CNN anchor Gene Randall. (Slate)

    On Your Last Nerve: Researchers Advance Understanding of Stem Cells  Nov 21, 2009
    20, 2009) Researchers from North Carolina State University have identified a gene that tells embryonic stem cells in the brain when to stop producing nerve cells called neurons ... NC State researchers, investigating the subventricular zone, one of the regions that retains stem cells, have identified a gene that acts as a switch -- transforming some embryonic stem cells into adult cells that can no longer produce new neurons ... The gene, called FoxJ1, increases its activity near the time of... (Science Daily)

    Experiment Aims to Predict PTSD  Nov 21, 2009
    Select Marine and Army units are undergoing a battery of physical and mental tests before deployment including genetic testing, brain imaging and stress exams ... They donated blood, urine and saliva samples so researchers can search for genetic biomarkers that might play a role ... Groundbreaking research published last year on adult survivors of child abuse suggests that specific variations of a gene increased their chances of developing PTSD. Scientists believe there may be many other gene... (CBS News -- Health)

    Saint Francis ranked high  Nov 20, 2009
    Saint Francis major service lines, which have received national recognition, include the Neurosciences Institute; Thomas G. Otto, MD, Orthopaedic Institute; Family BirthPlace, featuring the region s first Level III Neonatal Intensive Care Unit; Heart Institute; Gene E. Huckstep Emergency Center/Level III Trauma Center with Convenient Care; Cancer Institute; and Fitness Plus. Saint Francis is constructing a combined Heart Hospital and Cancer Institute, where patients will have access to advanced... (Park Hills Daily Journal, MO)

    Obituaries, Thursday, Nov. 19, 2009 (808)  Nov 20, 2009
    Kathy was preceded in death by her parents, Gene and Helen Adams; and father-in-law Noble Dixon ... Mills, Donald Eugene Gene, died Sunday. (Vincennes Sun Commercial, IN)

    Daily television guide  Nov 20, 2009
    Ellen DeGeneres Show at 9 a.m. on Chs. 5 and 9; 3 p.m. on Ch. (Boston Globe)

    Auditors criticize stimulus jobs data  Nov 20, 2009
    The doubts expressed by Devaney and Gene Dodaro, GAO acting comptroller general, at yesterday s House Oversight Committee hearing lend nonpartisan credence to general concerns about stimulus data. Devaney, who assumed his position in the spring, has repeatedly cautioned government officials at all levels that early data would probably contain errors. (Boston Globe)

    Beyond Genomics, Biologists and Engineers Decode the Next Frontier  Nov 20, 2009
    Despite rapid progress in understanding the information encoded in DNA and genes, scientists have achieved much less insight into the so-called "histone code," which determines why a gene in one cell functions differently than the same gene in another cell ... What makes this specialization possible is a set of instructions stored outside of genes or DNA -- "epigenetic" information -- that helps each cell adapt to its context ... The type and location of these add-ons can regulate nearby genes. (Science Daily)

    New research into the mechanisms of gene regulation  Nov 20, 2009
    A team led by Penn State's Ross Hardison, T. Ming Chu Professor of Biochemistry and Molecular Biology, has taken a large step toward unraveling how regulatory proteins control the production of gene products during development and growth ... As erythroid cells mature into red blood cells, the transcription factor, GATA-1, turns the genes responsible for making different proteins on and off ... Hardison's team worked with a special strain of mouse erythroid cells that lack the gene gata-1. (EurekAlert!)

    Hulking Hogan still controversial  Nov 20, 2009
    "When I was wrestling with the WWF in New York, Ric Flair was down south wrestling for the southern promotion and we always missed each other," says Hogan, AKA Terry Gene Bollea. "Just in the last few years of my career we had a chance to run into each other, but Vince McMahon didn't want us to fight, because he was trying to get other wrestlers like the Rock and Stone Cold Steve Austin to take my place. But now we get to fight in Australia and I can't imagine a better dream match than Hogan... (The Age, Australia)

    Obituaries, Wednesday, Nov. 18, 2009  Nov 20, 2009
    She formerly was active in the D.A.R. until her health prevented her continued interest in genealogy ... Mills, Donald Eugene Gene, died Sunday. (Vincennes Sun Commercial, IN)

    Despite Protests, UC Board Approves 32% Fee Hike  Nov 20, 2009
    "In a statement posted on the school's Web site, UCLA Chancellor Gene Block said:"As you likely know, the UC Regents are meeting on campus in Covel Commons ... Assembly Speaker Karen Bass, D-Los Angeles, told the full board Thursday that she would call for hearings in Sacramento to discuss the financial situation facing the state university system -- and education in general ... Employers generally have options when it comes to hiring. (TheSanDiegoChannel.com, CA)

    Cracked Corn: Scientists Solve Maize's Genetic Maze  Nov 20, 2009
    Cracked Corn: Scientists Solve Maize's Genetic Maze: Scientific American ... Cracked Corn: Scientists Solve Maize's Genetic Maze ... Boasting more genes than humans, the corn genome proved difficult to decode. (Scientific American)

    Common Pain Relief Medication May Encourage Cancer Growth  Nov 20, 2009
    Two recent retrospective studies found that breast and prostate cancer patients who received regional rather than general anesthesia had fewer recurrences ... The researchers found that opiates also promote angiogenesis, the growth of new blood vessels, and decrease barrier function--effects that may exacerbate diseases involving vascular leakiness including acute lung injury in experimental models ... Increased angiogenesis helps cancers thrive in a new site. (Science Daily)

    Turner Classic Movies Brings Holiday Cheer to Movie Fans With Digitally Remastered Gem Remember the Night  Nov 20, 2009
    8 p.m. - A Christmas Carol (1938), starring Reginald Owen and Gene Lockhart ... 9 a.m. - A Christmas Carol (1938), starring Reginald Owen and Gene Lockhart ... 11 p.m. - The Private Life of Sherlock Holmes (1970), starring Robert Stephens, Colin Blakely and Genevieve Page. (Yahoo! Wire -- Entertainment News)

    Der Manouel's rant  Nov 20, 2009
    Place an obit: (559) 441-6228. Web Search powered by YAHOO. (Fresno Bee -- Opinion)

    Veterans discussed their higher purpose, few regrets  Nov 20, 2009
    Veteran Eugene Folczyk ... Matthew Lor interviewed Eugene Folczyk of Chippewa Falls ... At first, Gene s family objected to his joining of the military, but his family accepted it later. (Chippewa Falls Chippewa Herald, WI)

    Nutrigenomics Researchers Replicate Gene Interaction With Saturated Fat  Nov 20, 2009
    19, 2009) Tufts University researchers have identified a gene-diet interaction that appears to influence body weight and have replicated their findings in three independent studies ... These associations were seen in the apolipoprotein A-II gene (APOA2) promoter ... "We believe this is the first time a gene-diet interaction influencing BMI and obesity has been replicated in as many as three independent study populations," said corresponding and senior author Jose Ordovas, PhD, director of the... (Science Daily)

    Waterlow struggled with son's mental illness, funeral told  Nov 20, 2009
    The gallery owner Gene Sherman was numb from shock. The Art Gallery of NSW's Edmund Capon was so distressed he could not bring himself to comment. (Sydney Morning Herald -- Australia)

    OL Leading UNCs Late Charge  Nov 20, 2009
    Defensive back Gene Robinson was nearly bent in a half during a nasty collision in Saturdays win over Miami and did not return to the game. The freshman was not at practice on Wednesday. (InsideCarolina.com)

    Obituaries, Tuesday, Nov. 17, 2009  Nov 20, 2009
    Donald Eugene Gene Mills ... Donald Eugene Gene Mills, 64, Zwolle, La. (Vincennes Sun Commercial, IN)

    Moffitt wins $19 million in stimulus grants  Nov 20, 2009
    1 million to Srikumar Chellappan to examine the role of the human gene ID1 in the progression of non-small-cell lung cancer. $2 million to David Fenstermacher to establish a health information system. (Tampa Bay Business Journal, FL)

    Another view: A new mammogram Rx  Nov 20, 2009
    Many women know they have a higher than average chance of getting breast cancer, because of family history, a known gene mutation, past exposure to radiation or other risk factors. These women know they have to be vigilant about screening. (Montana Standard, MT)

    Lee Memorial Health System healthier, financially  Nov 20, 2009
    There are a lot of hospitals envious of the position were in, said Gene Principi, a community member of the system Board of Directors finance committee. Related Stories. (The News-Press -- Business)

    Mammography Debate Puzzles Many  Nov 20, 2009
    The book also stated, "The other problem with mammography is obvious: Science only knows of one absolute carcinogen to human tissue on the planet, and that carcinogen is ionizing radiation. If the exposed cells don?t die, the DNA breaks and they mutate. Cancer rarely starts with a mutated gene; but a gene certainly can be mutated by an outside-the-body influence like the ionizing radiation of power lines or mammography. Mammography is ionizing radiation." ... Cancer rarely starts with a mutated... (CBS News)

    Causative gene of a rare disorder discovered by sequencing only protein-coding regions of genome  Nov 20, 2009
    Results show exome-sequencing might help identify genetic cause of thousands of disorders. This image shows data generated during exome sequencing ... For the first time, scientists have successfully used a method called exome sequencing to quickly discover a previously unknown gene responsible for a mendelian disorder. (EurekAlert!)

    Born to ride, badly  Nov 20, 2009
    A new study by University of California, Irvine (UCI) neuroscientists suggests that bad drivers may in part have their genes to blame. People with a particular gene variant performed more than 20 percent worse on a driving test than people without it - and a follow-up test a few days later yielded similar results ... This gene variant limits the availability of a protein called brain-derived neurotrophic factor (BDNF) during activity. (iAfrica.com)

    Oil from Biotech Soybeans Increases Key Omega-3 Fatty Acid in Humans  Nov 20, 2009
    They developed the new soybean variety by inserting one gene from another plant and one from a fungus to allow the soybean plant to produce SDA. The result is a soybean oil enriched in SDA, which when consumed allows the body to produce more EPA than if it started with ALA. ... "Our goal was to see if the oil from the genetically engineered soybean would raise red blood cell levels of EPA," he said ... Monsanto Co., the agricultural technology company that developed the genetically engineered... (Science Daily)

    Gene protects brain-eaters from mad cow-type disease  Nov 19, 2009
    WASHINGTON: Villagers in the highlands of Papua New Guinea who ritualistically ate human brains but did not die of a brain disease called kuru have a genetic mutation that protects them, researchers said Wednesday ... Kuru once wiped out entire generations of women in remote Papuan villages ... Dr Simon Mead of the University College London Institute and colleagues found that women in these communities were more likely to live to an old age if they had the protective gene. (India Times, India -- Health/Science)

    Common Herbal Medicine May Prevent Acetaminophen-Related Liver Damage, Says Researcher  Nov 19, 2009
    The finding came as a surprise to the scientists, who used a number of advanced genetic and genomic techniques in mice to identify a molecular pathway that counters acetaminophen toxicity, which leads to liver failure ... They compared how the drug is metabolized by the different strains and looked for variations in gene expression and changes in endogenous metabolites in response to acetaminophen administration ... They identified 224 candidate genes that might explain the resistant strain's... (Science Daily)

    Secondhand Smoke Exposure Worse for Toddlers, Obese Children  Nov 19, 2009
    (June 27, 2006) U.S. Surgeon General Richard H. Carmona today issued a comprehensive scientific report which concludes that there is no risk-free level of exposure to secondhand smoke ... 30, 2008) Researchers have discovered the first genetic evidence that secondhand smoke can worsen lung disease ... The report describes one gene variation that can weaken lung function as well as shorten the. (Science Daily)

    Down Syndrome Deficit Reversed in Mice  Nov 19, 2009
    The study, which was conducted in mice, is the first to show that boosting norepinephrine signaling in the brains of mice genetically engineered to mimic Down syndrome improves their cognition ... Down syndrome is a genetic disorder caused by an extra copy of chromosome 21 ... The researchers showed that, like humans with Down syndrome, the mice in their experiments experienced early degeneration of the locus coeruleus. (Science Daily)

    * Straight talk on GM crops crucial  Nov 19, 2009
    The planting of genetically modified (GM) crops is an issue that deserves discussion, because there are good arguments both for and against ... Genetic engineering can also generate products for medical and industrial purposes ... There are public doubts about the sources of genes used in GM crops. (Taipei Times, Taiwan -- World)

    Rabid cat put down in Newville  Nov 19, 2009
    gene wrote on Nov 18, 2009 10:02 PM:" this is a good reason for people not to let their cats run loose. They sure can't like them if they let them get rabies or get hit by cars. ". Local Advertisement Advertisement. (Carlisle Sentinel, PA)

    Sight Gone, but Not Necessarily Lost?  Nov 19, 2009
    D., a professor of molecular biology and genetics, neuroscience and ophthalmology at Johns Hopkins and a Howard Hughes Medical Institute investigator ... Three genes -- named Fz4, Ndp and Lrp5 -- previously were suspected to be involved in blood vessel development in the human retina ... Defects in any of these genes cause hypovascularization -- a lack of sufficient blood vessels -- in the retina. (Science Daily)

    Molecular Trigger Helps Prevent Aging, Disease  Nov 19, 2009
    Dietary restriction induces a transcription factor called CREB-binding protein (CBP), which controls the activity of genes that regulate cellular function ... The first part of the study looked at C. elegans, a species of roundworm, that were genetically altered to develop Alzheimer's disease-like symptoms ... CBP responds to changes in glucose within hours, indicating genetic communications respond quickly to fluctuations in dietary intake. (Science Daily)

    Combined Immunodeficiency Associated with DOCK8 Mutations  Nov 19, 2009
    The genetic causes of these variants are unknown ... We performed comparative genomic hybridization arrays and targeted gene sequencing ... Novel homozygous or compound heterozygous deletions and point mutations in the gene encoding the dedicator of cytokinesis 8 protein (DOCK8) led to the absence of DOCK8 protein in lymphocytes. (New England Journal of Medicine)

    Inflammatory Bowel Disease  Nov 19, 2009
    Genetic studies highlight the importance of host microbe interactions in the pathogenesis of these diseases. 1,2,3,4,5,6,7,8,9,10,11,12,13 Prominent among these genetic findings are genomic regions containing nucleotide oligomerization domain 2 (NOD2),14 autophagy genes,4,7,8,10 and components of the interleukin-23 type 17 helper T-cell (Th17) pathway ... Innate-Immune-Response Genes and Crohn's Disease. (New England Journal of Medicine)

    Obituaries, Wednesday, Nov. 18, 2009 (834)  Nov 19, 2009
    She formerly was active in the D.A.R. until her health prevented her continued interest in genealogy ... Mills, Donald Eugene Gene, died Sunday. (Vincennes Sun Commercial, IN)

    A Novel Protective Prion Protein Variant and Kuru Exposure  Nov 19, 2009
    Methods We performed genetic and selected clinical and genealogic assessments of more than 3000 persons from Eastern Highland populations, including 709 who participated in cannibalistic mortuary feasts, 152 of whom subsequently died of kuru. Results Persons who were exposed to kuru and survived the epidemic in Papua New Guinea are predominantly heterozygotes at the known resistance factor at codon 129 of the prion protein gene (PRNP) ... Genealogic analysis reveals a significantly lower... (New England Journal of Medicine)

    Obituaries, Tuesday, Nov. 17, 2009  Nov 19, 2009
    Donald Eugene Gene Mills ... Donald Eugene Gene Mills, 64, Zwolle, La. (Vincennes Sun Commercial, IN)

    As many as 22 injured in Minn. tour bus crash  Nov 19, 2009
    Freeborn County Chief Deputy Gene Arnold says as many as 22 people are thought to be injured in the crash, which happened shortly before 3:30 p.m. Wednesday about 2 miles west of Austin. He says six medical helicopters were responding. (WSVN-TV Miami, FL)

    UNC stimulus take passes $127M  Nov 19, 2009
    Guang Gua, a sociology professor, will use his $1 million grant to study gene variations and epigentic expression on risky behaviors such as binge drinking, smoking, illegal drug use and delinquency ... And Stephen Frye, a professor of medical chemistry, will use his $873,000 grant to study the regulation of the genetic material chromatin. (Triangle Business Journal)

    M&S Christmas TV ad 'offensive'  Nov 19, 2009
    Glenister, who played chauvinist DCI Gene Hunt in the BBC show, says: "That girl prancing around in her underwear.". The ad cuts to a model, wearing a bra and knickers, who asks: "Moi?" M&S said the complaints had come as a surprise. (BBC News)

    NanoString Technologies announces research collaboration with the Broad Institute  Nov 19, 2009
    The three-year collaboration is also designed to explore ways to expand how NanoString's next-generation digital gene expression technology can be applied to improve basic and clinical research. As part of the collaboration, the Broad Institute will use NanoString's nCounterTM Analysis System to decipher entire networks of genes to identify how these genes work together to carry out biological functions ... To support this effort, NanoString will design custom CodeSets (molecular barcodes... (EurekAlert! -- Business News)

    Curtain Time: Choreography Festival at the McCallum (43)  Nov 19, 2009
    Nov. 22, with a continuation of his tribute to 1920s best-selling recording artist, composer and crooner, Gene Austin, with I m in a Mellow Mood, Sun ... Also in the cast are Fred Ellsberg, Lou Reinitz, Paul Runyon, Eileen Heckle, Gene Gambale, Jerry Freedman, Zenda Saraydarian, Merle Freedman, Gary Miller, James Armstrong, Rose Borses, and Darryl Jacobs ... Tickets: $15 general, $13 students, (760) 773-2565, also at COD Bookstore. (Desert Entertainer, CA)

    Twilight of Our Youth: It isnt just a tween phenomenon. Women in their 30s and beyond are addicted to Stephenie Meyers vampire saga, too, Sarah Hepola, Salon  Nov 19, 2009
    Today's grown-ups are more comfortable than perhaps any previous generation holding on to the playthings of childhood ... Seventeen years ago a high school cheerleader in Southern California learned that she was the one girl of her generation chosen to stop the spread of evil -- namely, by slaying vampires. (Harper's Magazine)

    Is the NSA spying on U.S. Internet traffic?  Nov 19, 2009
    Bush's attorney general won't dare explain the real basis for warrantless spying on Americans: Pure, unbridled executive power ... Alberto Gonzales, White House counsel (2001-2005), and attorney general (2005-2008) ... Most important, in a Jan. 25, 2002, opinion reportedly written with David Addington, Gonzales paved the way for exempting al-Qaida detainees from the Geneva Conventions. (Yahoo News -- Online Privacy)

    Saint Francis ranked high  Nov 19, 2009
    Saint Francis major service lines, which have received national recognition, include the Neurosciences Institute; Thomas G. Otto, MD, Orthopaedic Institute; Family BirthPlace, featuring the region s first Level III Neonatal Intensive Care Unit; Heart Institute; Gene E. Huckstep Emergency Center/Level III Trauma Center with Convenient Care; Cancer Institute; and Fitness Plus. Saint Francis is constructing a combined Heart Hospital and Cancer Institute, where patients will have access to advanced... (Park Hills Daily Journal, MO)

    Roggeman nominated for FedEx Orange Bowl Courage Award  Nov 19, 2009
    Roggeman, 46, in his fifth season as an ECU assistant, was diagnosed with the cancer of the lymphatic system last summer. He continued coaching while undergoing treatments, but left the team in late September in order to undertake a more aggressive treatment plan. (East Carolina Sports -- Rivals.com)

    Too many litters, too many pets  Nov 19, 2009
    Last Updated on Thursday, Nov 12, 2009 - 08:47:59 pm AKST. News and Features for Wasilla, Alaska. (Wasilla Frontiersman, AK)

    5 Genetic Regions Tied to Irritable Bowel  Nov 19, 2009
    (WebMD) Five newly identified genetic regions may help explain how childhood inflammatory bowel disease (IBD) develops. A new study shows at least one of the five new gene regions associated with childhood IBD is directly involved in the biological process that causes the painful inflammation of the digestive tract associated with the disease ... "This is an evolving story of discovering what genes tell us about the disease," says researcher Robert N. Baldassano, MD, director of the Center for... (CBS News -- Health)

    Judges: Seattle Biotech Can Pursue $23M Claim  Nov 19, 2009
    By GENE JOHNSON Associated Press WriterSEATTLE November 18, 2009 (AP) The Associated Press. Seattle biotechnology firm Cell Therapeutics Inc. can pursue claims for nearly $23 million against a former consultant, a federal appeals court ruled Wednesday. (ABC News -- Wire)

    Reich: Public Option Increases Health Costs  Nov 19, 2009
    By: Gene J. Koprowski. Article Font Size. (Newsmax)

    2New Cancer Guidelines Say to Start Mammograms at 50, Not 40»  Nov 19, 2009
    The guidelines are for the general population, not those at high risk of breast cancer because of family history or gene mutations that would justify having mammograms sooner or more often. 0000178B. (Fox News)

    Immune tribe 'indicates CJD hope'  Nov 19, 2009
    The Papua New Guinea tribe developed strong genetic resistance after a major epidemic of the CJD-like disease, kuru, spread mostly by cannibalism ... But a gene variation, G127V, found in people from the Purosa valley region of the Eastern Highlands seems to offer high or even complete immunity ... The fact that this genetic evolution has happened in a matter of decades is remarkable. (BBC News -- Health)

    Game improvement helps English visitor to second ace  Nov 19, 2009
    Who: Gene Summers, 79, North Fort Myers ... "Who: Joyce Sanders, 73, Fort MyersWhere: Eastwood Golf Course, No. 16, 134 yards, 7-woodHer ace: If only it were as easy as saying it. Driving to the 16th hole, Joyce Sanders was having so poor a round, she said to her playing partners, You know, if I had a hole in one it would not help my score. Sure enough, Sanders shot hit the green and fed toward the hole. We heard it go clink, said Sanders, president of the Eastwood Ladies Golf Association.... (The News-Press -- Sports)

    Detonating Tumor-Killer Drug in Cancers on Command  Nov 19, 2009
    They began by engineering the salmonella to include the gene for TRAIL so that it gets expressed under control of the RecA promoter. Then Ganai injected 2 million S. typhimurium cells that carried the engineered RecA promoter and TRAIL gene into groups of genetically identical mice with mammary tumors, that is, breast cancer ... Forbes and Ganai say these experiments show that they can control when the bacteria produce the anti-tumor drug by engineering S. typhimurium with a genetic switch that... (Science Daily)

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