New Nanomethod Paves the Way for New Measuring Technology and Hypersensitive Sensors Nov 21, 2009
12, 2009) Scientists have developed a highly sensitive measuring method with which the efficiency of gene transfer in cases if cardiovascular diseases can be investigated. The researchers determine, accurate. (Science Daily)
Phylogeny for promiscuous bacterial species Nov 19, 2009
Phylogeographic reconstruction of a bacterial species with high levels of lateral gene transfer ... Phylogeographic reconstruction of some bacterial populations is hindered by low diversity coupled with high levels of lateral gene transfer ... A comparison of recombination levels and diversity at seven housekeeping genes for eleven bacterial species, most of which are commonly cited as having high levels of lateral gene transfer shows that the relative contributions of homologous recombination... (BioMed Central)
The Effect of Transgenic Squash on ... Nov 5, 2009
Modified Gene Transfers to Wild Squash ... Scientists may need to find a way to restrict gene transfer from transgenic plants to wild types within the ecosystem. (Suite101.com)
Horizontal Gene Transfer and Symbio... Nov 4, 2009
Horizontal Gene Transfer and Symbiogenesis. Horizontal Gene Transfer and Symbiogenesis ... How Lateral Gene Transfer Drives Genome Evolution. (Suite101.com)
1 shot of gene therapy and children with congenital blindness can now see Oct 25, 2009
The University of Pennsylvania Health System (UPHS) includes its flagship hospital, the Hospital of the University of Pennsylvania, rated one of the nation's top ten "Honor Roll hospitals by U.S.News Report; Pennsylvania Hospital, the nation's first hospital; and Penn Presbyterian Medical Center, named one of the nation's "100 Top Hospitals" for cardiovascular care by Thomson Reuters. In addition UPHS includes a primary-care provider network; a faculty practice plan; home care, hospice, and... (EurekAlert!)
Worry about human ethics Oct 16, 2009
Three possible consequences of GM foods present rational risks: allergic reactions, gene transfer and outcrossing. The first is self-explanatory. (India Times)
Investment In Parkinson's Disease Data Bank Yields Potential Therapy Oct 14, 2009
6, 2009) A Michigan hospital is embarking on a research study for advanced Parkinson's disease using a state-of-the-art treatment called gene transfer. The clinical trial will test whether gene transfer. (Science Daily)
Michigan hospital launches gene therapy study for Parkinson's disease Oct 7, 2009
A Michigan hospital is embarking on a research study for advanced Parkinson's disease using a state-of-the-art treatment called gene transfer. The clinical trial will test whether gene transfer therapy is able to restore better mobility in Parkinson's patients who have lost responsiveness to drug therapy ... The gene transfer is done through a catheter that is removed shortly after its placement. (EurekAlert!)
Scientists Jump-start Heart By Gene Transfer Oct 7, 2009
Closed Heart Surgery': Scientists Jump-start The Heart By Gene Transfer ... Closed Heart Surgery': Scientists Jump-start The Heart By Gene Transfer ... "The advent of molecular motor-based gene transfer for the failing heart will hopefully improve cardiac function and quality of life for heart failure patients.". (Science Daily)
Obama Pushes GM Foods on Ghana, Africa Sep 5, 2009
According to documents released from a lawsuit, the scientific consensus from the agency was that GM foods were inherently dangerous, and might create hard-to-detect allergies, poisons, gene transfer to gut bacteria, new diseases and nutritional problems. (See http://www. (Ghana Web, Ghana)
Magnetic Microbe Genome Attracting Attention For Biotech Research Aug 14, 2009
Matsunaga explained that this suggests that the core magentosome genes may have been established in these bacteria by several horizontal gene transfer events, rather than being passed down through a lineage. In addition to illuminating core magnetosome genes, the group expects that their work on RS-1 will be a stepping-stone to manipulation of magnetosomes for new technologies. (Science Daily)
Cyanobacterial contribution to the genomes of the plastid-lacking protists Aug 11, 2009
The origins of those genes might be due to lateral gene transfer events, or an ancient primary or secondary endosymbiosis before the diversification of bikonts. Our data also show that all genes identified in this study constitute multi-gene families with punctate distribution among eukaryotes, suggesting that the transferred genes could have survived through rounds of gene family expansion and differential reduction. (BioMed Central)
Methods for gene transfer in stem cells featured in Cold Spring Harbor Protocols Aug 6, 2009
Aug. 5, 2009) Vectors derived from retroviruses are useful tools for long-term gene transfer because they allow stable integration of transgenes and propagation into daughter cells ... DNA transposons offer an effective, alternative method for nonviral gene transfer that avoids the safety concerns associated with viral vectors. (EurekAlert!)
Differential baseline and response profile to IFN-gamma gene transduction of IL-6/IL-6 receptor-alpha secretion discriminate primary tumors versus bone marrow metastases of nasopharyngeal carcinomas in culture Jun 5, 2009
Our results showed that cultured P-NPCs and BM-NPCs could be distinguished from one another on the basis of their differential baseline secretion pattern of IFN-gamma, IL-6 and IL-6Ralpha, and their differential response profiles to IFN-gamma gene transfer of the production of these three soluble molecules. These results suggest that the IL-6 and IFN-gamma pathways in a background of genetic instability be involved in the acquisition of metastatic behaviour in BM-NPCs. (BioMed Central)
Monkeys glow with gene transfer breakthrough May 28, 2009
The Sydney Morning Herald - Business News, World News & Breaking News in Australia Skip directly to: Search Box, , , Text Version. Five transgenic marmoset offspring - (a) Hisui, (b) Wakaba, (c) Banko, (d) Kei (left) and Kou (right) - after their birth at the Central Institute for Experimental Animals at Japan's Keiko University. (Sydney Morning Herald -- World)
New approach for HIV vaccine May 24, 2009
WASHINGTON: Using gene transfer technology, scientists have developed a new approach to overcome the biggest hurdle in the development of an effective HIV vaccine. The researchers used gene transfer technology, which produces molecules that block infection, to successfully protect monkeys from infection by a virus closely related to HIV-the simian immunodeficiency virus, or SIV-that causes AIDS in rhesus monkeys ... Using gene transfer technology, scientists have developed a new approach to... (India Times, India)
Gene Transfer Technology May Lead To HIV Vaccine May 19, 2009
By using gene transfer technology that produces molecules that block infection, the scientists protected monkeys from infection by a virus closely related to HIV the simian immunodeficiency virus, or SIV that causes AIDS in rhesus monkeys ... Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys. (Science Daily)
* Hello Van Gogh,can you hear me now? Apr 16, 2009
Carl Woese, an evolutionary biologist at the University of Illinois, Urbana-Champaign, has theorized that such horizontal gene transfer prevailed in the primordial soup before cells got locked in species. We will be fine with it, Dyson has said, when children start breeding miniature dinosaurs with rabbit ears and other exotic creatures for science fairs the way horticulturists turn out new breeds of tomatoes. (Taipei Times, Taiwan -- Sports)
Genome Evolution Driven by Host Adaptations Results in a More Virulent and Antimicrobial-Resistant Streptococcus pneumoniae Serotype 14 Apr 13, 2009
Comparative genomic analysis revealed that the CGSP14 acquired a number of new genes by horizontal gene transfer (HGT), most of which were associated with virulence and antimicrobial resistance and clustered in mobile genetic elements. The most remarkable feature is the acquisition of two conjugative transposons and one resistance island encoding eight resistance genes. (BioMed Central)
Aphids Borrowed Bacterial Genes To Play Host Mar 16, 2009
New research suggests that the aphids' ability to host Buchnera depends on genes they acquired from yet another species of bacteria via lateral gene transfer (LGT) ... LGT (also referred to as horizontal gene transfer) occurs when genetic material from one organism finds its way into another organism other than its offspring ... Aphids acquired symbiotic genes via lateral gene transfer. (Science Daily)
Symbiosis across evolutionary time Mar 13, 2009
Aphids acquired symbiotic genes via lateral gene transfer ... In this study, in order to assess the possibility of lateral gene transfer, we determined the full-length sequences of these transcripts, and performed detailed structural and phylogenetic analyses ... In this study, we obtained several lines of evidence indicating that aphids acquired genes from bacteria via lateral gene transfer and that these genes are used to maintain the obligately mutualistic bacterium, Buchnera. (BioMed Central)
Magnetic Nanoparticles Navigate Therapeutic Genes Through The Body Mar 13, 2009
12, 2009) Scientists of the national German metrology institute, the Physikalisch-Technische Bundesanstalt (PTB), have developed a highly sensitive measuring method with which the efficiency of gene transfer in cases if cardiovascular diseases can be investigated ... In a joint study with the University of Bonn it became clear: By means of the magnetic method it is possible to dramatically increase the efficiency of the gene transfer in comparison to the non-magnetic method ... In a joint study... (Science Daily)
Emergence of Ciprofloxacin-Resistant Neisseria meningitidis in North America Feb 26, 2009
Sequencing of the gene encoding subunit A of DNA gyrase (gyrA) revealed a mutation associated with fluoroquinolone resistance and suggests that the resistance was acquired by means of horizontal gene transfer with the commensal N. lactamica. In susceptibility testing of invasive N. meningitidis isolates from the Active Bacterial Core surveillance system between January 2007 and January 2008, an additional ciprofloxacin-resistant isolate was found, in this case from California. (New England Journal of Medicine)
What do you know about GMOs? Feb 15, 2009
GMOs or genetically modified organisms are plants, bacteria or animals that have acquired novel genes from other organisms by laboratory gene transfer methods ... GMOs or genetically modified organisms are plants, bacteria or animals that have acquired novel genes from other organisms by laboratory gene transfer methods. (Westerly Sun, RI)
Device aims to decrease wait period for patients needing immunotherapy Feb 14, 2009
"More importantly, it's a very safe method of gene transfer.". Multiple relapsed ALL in pediatric patients is a rapidly progressive cancer that is often resistant to chemotherapy, leading to poor survival prognosis. (EurekAlert!)
Scientists Ask: What Would Darwin Do? Feb 13, 2009
Milner continued: "Also, I think he would have been astounded at the some of the twists and turns of modern theory: endosymbiosis (cells made up of combinations of critters), lateral gene transfer (a challenge to the vertical tree of life), self-organization (the mystery of how cells combine into larger entities). "Also, the science of genetics, which originated after his death, would have opened a whole new window for him: how genes work, either as 'blueprints' or 'switches,' the 'junk DNA'... (Fox News)
Bogus Stem Cell Therapies Sold on Internet Feb 7, 2009
Previous scientific guidelines and regulations have regulated human-subjects research and clinical research in general, as well as gene transfer research, but not stem cell research, which poses a number of independent issues. "Most of the time, stem cell products are presenting entirely novel products that are unpredictable in humans," Hyun said. (MEDLINEplus)
