Gene therapy halts brain disease Nov 6, 2009
Illness featured in Lorenzo's Oil movieFeatured in the 1992 movie "Lorenzo's Oil," ALD is a rare hereditary condition caused by a deficiency of a protein involved in fatty acid degradation. Sufferers gradually lose the myelin sheath, a protective layer coating the brain's nerve fibers, leading to disabilities such as blindness, deafness, seizures and progressive dementia. (MSNBC -- Health)
Dementia: Rare Brain Disorder Is Highly Hereditary Nov 5, 2009
4, 2009) New research shows that a rare brain disorder that causes early dementia is highly hereditary ... The study also found that behavioral problems associated with frontotemporal dementia were the most likely to be hereditary, while language problems were the least likely to be hereditary. (Science Daily)
Acne Triggers Nov 4, 2009
It will be interesting to analyze what triggers acne and whether the life style is also a deciding factor, in addition to the hereditary and hormonal causes ... A hereditary predisposition for acne formation has been noted by most studies. (Suite101.com)
Ex-Guantanamo detainees begin new lives in Palau Nov 4, 2009
Palauan citizenship is strictly hereditary, and the Uighurs will not be eligible for Palauan passports. Toribiong is taking a personal interest in the resettlement. (MSNBC -- International)
Understanding Diabetes in America Nov 4, 2009
Most resources devoted to understanding diabetes offer a dismal explanation, claiming that the cause for diabetes is either unknown, hereditary, or is a factor of age and/or race. However, Dr. Gabriel Cousens offers a different perspective on the nature of this degenerative disease, one which has affected the lives of over 20 million people across the United States. (Suite101.com)
Renal Cancer: Protein Triggers A Snowball Effect Nov 3, 2009
The loss of pVHL is in part hereditary due to mutations of the gene. There are two copies of the VHL gene. (Science Daily)
Genetics may hold key to prevention, treatment Nov 3, 2009
Sajer said mutations in these genes, known as breast ovarian cancer syndrome, have been linked to the development of hereditary breast and ovarian cancer, and are especially common in young people and in the population she treats in the Concord area. According to Sajer, the lifetime risk of breast cancer in the general population is about 8 percent (for people who live to be 70 years old). (Bolton Common, MA)
Ovarian cancer hard to detect Nov 3, 2009
An estimated 1 in 10 or 10 percent of ovarian cancers have a strong hereditary link, he said, while the other 90 percent probably result from a combination of genetic and environmental factors. And there are several hereditary syndromes, which elevate the ovarian cancer risk, as part of their conditions. (Florida Today)
Newsoms fulfill mom's last wish with charity Nov 2, 2009
" Hereditary concerns Mayor Newsom and his wife, actress Jennifer Siebel Newsom, recently welcomed their first daughter, Montana Tessa Siebel Newsom. "When I reflect on how Hilary took care of our mother, I'm so happy we had a daughter," said Newsom. "I know Montana will be there for me. " These particular parents, close to the ages when their mothers got sick, are aware of the hereditary concerns surrounding breast cancer. At 39, Newsom Callan chose to undergo a CT scan, an MRI and a series of... (San Francisco Chronicle)
650-Year-Old Cairo Mosque Restored Nov 1, 2009
The agency funded by the Agha Khan, hereditary leader of the Nizari branch of Shiite Islam is carrying out a wider urban renewal project in al-Darb al-Ahmar. In recent years, the Egyptian government also has carried out extensive renovations on mosques and sought to increase the amount of tourism to Islamic sites. (Fox News)
Heart study examines local youth Nov 1, 2009
Jeni Michelson, coordinator of the Muscatine Heart Study, said many students are likely related to the first 1970 batch of students, which will provide hereditary links. Students in the study will not only receive information about their health status, but 20 in Pearl City Dollars to help re-invest in the community. (Muscatine Journal, IO)
14th Century Cairo Mosque Restored To Glory Oct 31, 2009
The agency - funded by the Agha Khan, hereditary leader of the Nizari branch of Shiite Islam - is carrying out a wider urban renewal project in al-Darb al-Ahmar. In recent years, the Egyptian government also has carried out extenstive renovations on mosques in the area and has sought to increase the amount of tourism to Islamic sites. (CBS News -- World)
Caltech researchers show efficacy of gene therapy in mouse models of Huntington's disease Oct 31, 2009
The research described in the Journal of Neuroscience paper, "Intrabody Gene Therapy Ameliorates Motor, Cognitive, and Neuropathological Symptoms in Multiple Mouse Models of Huntington's Disease," was funded by the Hereditary Disease Foundation and the National Institute of Neurological Disorders and Stroke. Visit the Caltech Media Relations website at. (EurekAlert!)
A painful family inheritance for former Georgetown resident Oct 30, 2009
Hereditary breast cancers account for 5 to 10 percent of all cases, usually due to mutations in the so-called BRCA1 and BRCA2 genes, according to the National Cancer Institute ... Mutation of these genes has been linked to the development of hereditary breast and ovarian cancer ... Hereditary breast cancers account for 5 to 10 percent of all breast cancers and 10 to 15 percent of ovarian cancers among white women in the United States. (Georgetown Record, MA)
2009 Glaucoma Week is launched Oct 30, 2009
Dr Braimah noted that glaucoma affected Africans and African Americans than the whites and women more than men and attributed it to hereditary and the short sightedness of most women ... Dr Braimah said it affected people 30 years and above but because it was hereditary children could also be affected. (Ghana Web, Ghana)
Screening Guidelines For Breast, Cervical And Colorectal Cancers Redefined Oct 28, 2009
genetic history of Hereditary Nonpolyposis Colorectal Cancer or a clinical history suggesting such. or inflammatory bowel disease (ulcerative colitis or Crohn's disease). (Science Daily)
Maternal Mice Fed High-Fat Diet Produce Larger Pups Oct 28, 2009
Until very recently, scientists believed that our genes were the sole carrier of hereditary information. However, in addition to inheriting genes from our parents, we can also inherit their epigenetic "switches" that turn our genes on or off. (Science Daily)
Gene Therapy Offers Hope for Severe Hereditary Eye Disease Oct 27, 2009
Youngest patients have best chance at some visual recovery, research suggests. Saturday, October 24, 2009. (MEDLINEplus)
Read today's letters to the editor Oct 26, 2009
Lawyers are suing doctors for everything from torn toenails to hereditary genetic defects. You want premiums to go down. (The News-Press -- Opinion)
Congenital Blindness: One Shot Of Gene Therapy Oct 26, 2009
For Bennett, the results build on nearly 20 years of gene studies on hereditary blindness, starting with pioneering work in mice and dogs ... 9, 2008) No significant adverse effects were reported during a safety trial testing gene therapy on three patients with a type of hereditary blindness called Leber congenital amaurosis type 2. (Science Daily)
1 shot of gene therapy and children with congenital blindness can now see Oct 25, 2009
For Bennett, the results build on nearly 20 years of gene studies on hereditary blindness, starting with pioneering work in mice and dogs ... The University of Pennsylvania Health System (UPHS) includes its flagship hospital, the Hospital of the University of Pennsylvania, rated one of the nation's top ten "Honor Roll hospitals by U.S.News Report; Pennsylvania Hospital, the nation's first hospital; and Penn Presbyterian Medical Center, named one of the nation's "100 Top Hospitals" for... (EurekAlert!)
Trembling hands and molecular handshakes Oct 24, 2009
A novel protein structure involved in hereditary neurodegeneration ... Expansion of the triplet sequence beyond 200 copies leads to Fragile X Syndrome (FXS), which is the second most common cause of hereditary mental retardation after Down's syndrome. (EurekAlert!)
Survivors share real-life stories in I Am Not My Breasts Oct 24, 2009
Younger women should not assume, if they are not at hereditary risk, that they are safe. Most of the people in the audience also have been personally affected by breast cancer in particular or cancer in general as survivors, family members, friends, caregivers and medical professionals, she said. (Weymouth News, MA)
One Tri-City girl's death gives another life Oct 24, 2009
Kayla was born with cystic fibrosis, although it wasn't until she was 5 that a doctor finally figured out she had the hereditary disease. Without healthy lungs, she's developed interests that allow her body to remain still but her mind to wander to other worlds. (Longview Daily News, WA)
Dream Factory sends Fulton girl on Disney cruise Oct 24, 2009
"Callaway Dream Factory volunteer Tim Bach said Wednesday night's gathering was an opportunity to bring Sarah and the firefighters -- some of whom shaved their heads in July as part of a Buzz the Red, White and Blue fundraiser -- together. "It gives them a chance to meet her," Bach said.He said Sarah -- who was born with a rare bone disorder called Hereditary Multiple Exostoses, which causes bone tumors and extra bones to grow -- was recommended to the program by her University of Missouri... (Fulton Sun, MO)
Rosella Howe, 97; feminist, poet loved English language Oct 23, 2009
Mrs. Howe s longevity seemed both hereditary and self-promoted. Rosella took care of herself, Edwards said. (Boston Globe)
Empower Yourselves Oct 23, 2009
Is breast cancer hereditary. Only five percent of women with breast cancer carry the mutated gene, BRCA1 or BRCA2 which can cause breast cancer. (The Star Online, Malaysia)
Acreage residents seek cancer answers from health officials Oct 21, 2009
Here is a clip from the report I found:"Risk Factors--Like most pediatric cancers, no specific risk factor explains more than a small proportion of childhood brain tumors. The known risk factors for childhood brain tumors include ionizing radiation and certain genetic conditions. Therapeutic doses of ionizing radiation to the head increase the risk of brain tumors in children (Bunin, 2000). Some hereditary conditions clearly predispose to CNS cancer in children. These include neurofibromatosis... (The Palm Beach Post)
Xenotropic Murine Leukemia Virus-related Virus May Not Be Associated With Human Prostate Cancer Oct 20, 2009
Previously, the HPC1 locus (hereditary prostate cancer locus-1) has been identified as a hereditary factor associated with a predisposition to prostate cancer. The gene RNaseL is found within this locus. (Science Daily)
Pets not immune to cancer Oct 19, 2009
We feel for lumps and bumps," said Heller. But "if an owner feels a lump in the mammary gland in a cat, they should call (their veterinarian) right away," said Sinnigen. Discharge from the nipples is another potential sign of mammary tumors in a non-lactating dog or cat. It is unknown if there is a hereditary component to mammary cancer in animals such as Mouse and May. "The vast majority of cat owners don't know who the parents are," said Sinnigen. A family tree including grandmothers and... (Allston Brighton TAB, MA)
Are Commercial Genetic Tests Worth Taking? Oct 16, 2009
Some are tried and true, such as those to detect the BRCA 1 and 2 genes, which heighten a woman's risk for breast and ovarian cancer, or specific tests to figure the risk for Lynch syndrome, a hereditary form of colon cancer. But take the example of several much-hyped genetic tests to help determine what type or what dose of antidepressant would be effective for different individuals. (MEDLINEplus)
New Cancer Gene Discovered Oct 15, 2009
26, 2007) A new hereditary breast cancer gene has been discovered. Researchers found that women with a certain hereditary deformity syndrome run a nearly twenty times higher risk of contracting breast cancer. (Science Daily)
Heart of the Matter: Granddaughter hopes to join Framingham study Oct 15, 2009
Valerie Flynn plans to take the study's follow-up report to her doctor to see if the dementia her mother suffered from is hereditary, and she expects to donate her own brain. Her youngest daughter wants to follow suit, if the fourth-generation funding is approved. (Framingham TAB, MA)
Loss Of Tumor Supressor Gene Essential To Transforming Benign Nerve Tumors Into Cancers Oct 14, 2009
8, 2008) Scientists have tracked down the cells responsible for neurofibromatosis type 1, a disfiguring, incurable condition and one of the most common hereditary disorders. Neurofibromatosis type 1, or NF1. (Science Daily)
Breast Cancer Gene: Who Wants To Know? Oct 13, 2009
If a woman has a history of breast cancer, but the BRCA mutation doesn't run in her family, there's a good chance there's a hereditary component to the cancer that simply hasn't been identified by scientists yet. However, if the BRCA mutation does run in a woman's family and she tests negative, her risk of breast cancer is the same as that of the general population -- which the National Cancer Institute estimates is about a 13. (Click2Houston, TX)
FDA approves CSL Behrings agioedema drug Oct 13, 2009
The Food and Drug Administration has granted marketing approval for Berinert, a treatment developed by for acute abdominal or facial attacks in patients with hereditary angioedema. Hereditary angioedema is a rare and serious genetic disorder caused by a deficiency of the protein C1-INH. Symptoms include swelling in the face and the abdomen ... An estimated 6,000 to 10,000 or more people have hereditary angioedema in the United States. (Philadelphia Business Journal, PA)
Authorities seize 20 dogs from Toledo property Oct 10, 2009
Hahn said the hair loss on some of the dogs is not a result of poor living conditions, but it instead comes from a condition called alopecia, which can be hereditary ... MizLiz wrote on Oct 9, 2009 7:10 PM:" Just read that article another time...the hoarder says the dogs have lost their coasts because of a hereditary disease called "alopecia". Sorry, Toots. Those animals have "blown their coats" because of extreme stress and poor diet. Our second Pom was rescued from just such a place. Some of... (Longview Daily News, WA)
Pianist Misha Dichter discusses his frightening hand ailment, surgery, and recovery Oct 9, 2009
The condition is generally hereditary, and it was familiar to Dichter in the most painful way: His father had suffered from it in the 1950s and endured two botched surgeries that failed to correct the problem. My memories of his hands, to the end of his life, are of just horrendously contorted fingers, bent tightly toward the palm, Dichter says. (Boston Globe)
the melrose thursday 10: Robert Forshay Oct 9, 2009
Mary s mother also succumbed to ALS is the disease hereditary ... Note: According to the ALS Association, ALS is directly hereditary in only a small percentage of families. (Allston Brighton TAB, MA)
New type of genetic change identified in inherited cancer Oct 5, 2009
Inherited differences in gene copy number, known as copy number variation (CNV), have been implicated in some hereditary diseases but none of the previously discovered familial cancer genes has had CNV as the genetic change. "This alteration is unlike anything we have ever seen before in families that tend to develop the same kind of cancers," says Michael Kelley, M.D., an associate professor at Duke University Medical Center and senior author of the study appearing in Nature Genetics. (EurekAlert!)
Know all about 'hair fall' Oct 5, 2009
There are many causes for baldness - alopecia areata, syphilis, traction alopecia, seborrhoeic dermatitis, post-febrile condition, debility and emaciation, during lactation, endocrine disorders, stress and strains, certain drugs like hydration, etc, hereditary factors, injury, burns, leprosy and X-rays burns, etc. Topics. (India Times, India)
Mom hopes Chinese treatment can save her sight Oct 4, 2009
Two of her uncles and a great aunt also went blind from Leber Hereditary Optic Neuropathy, which can wipe out the central vision in both eyes within days or weeks ... Leber Hereditary Optic Neuropathy. (Daytona Beach News Journal)
Kenya: Affordable New Weapon Against Cervical Cancer Oct 3, 2009
She adds, "I am told cancer is hereditary. My sisters and I have been worried sick at the possibility of testing positive. However, we have never undergone the test due to the prohibitive costs of getting checked. Fear has also been a contributing factor, the idea of waiting for the results is simply agonising.". Now that the visual inspection is being offered, the thirty-eight year old says she may brave it all and get tested. (allAfrica.com)
Breast Cancer Awareness Month in Wilmington: Thinking positive Oct 2, 2009
Newcomb said she doesn t believe the cancer is hereditary, as there is no evidence of it in her family s history. We don t know where it came from, she said. (Wilmington Advocate, MA)
Is multiple sclerosis hereditary? Oct 1, 2009
Is multiple sclerosis hereditary ... Is multiple sclerosis hereditary ... Is multiple sclerosis genetic or hereditary. (CNN -- Health)
Gene Tests Rate Sudden Cardiac Death Risk Oct 1, 2009
And because the disease is hereditary, Brown's children are being tested, as well. Ackerman said, "We found the cause -- this X marks the spot -- now it actually becomes simple for her two sons to see if they are among the haves or the have-nots.". (CBS News -- Health)
Recurrence of BSEP Deficiency after Liver Transplantation Oct 1, 2009
Severe bile salt export pump (BSEP) deficiency is a hereditary cholestatic condition that starts in infancy and leads to end-stage liver disease. Three children who underwent orthotopic liver transplantation for severe BSEP deficiency had post-transplantation episodes of cholestatic dysfunction that mimicked the original disease. (New England Journal of Medicine)
The Full Story: Brown's speech Sep 30, 2009
1528 Mr Brown also cheers Labour delegates with that old favourite - the hereditary peers in the House of Lords - if Labour wins the next election they'll be gone for good he says. Labour promising a referendum. (BBC News -- UK)
Nobody wondered why they were there (375) Sep 30, 2009
She said her cancer is hereditary, but no one in her family has it. Since it isn't a common form of cancer, she has volunteered for studies to see what medicines may work. (Fort Madison Daily Democrat, IO)
Incest: an age-old taboo Sep 25, 2009
Opponents of the incest ban also argue there are double standards, noting that no-one would ban those with hereditary diseases from reproducing. In some countries, the law has tried to take into account the risks while legalising incest in certain circumstances. (BBC News -- Entertainment)
Thomas J. Lyberg Sep 24, 2009
In 1993, Thomas was left disabled with hereditary heart disease. Tom is survived by: his parents, Ennis and Madonna Lyberg; his siblings, Pete Lyberg, Becky Lyberg-Schuebel, Hugh Lyberg, Jeff Lyberg, James Lyberg; and many aunts, uncles, nieces and nephews; and too many friends to numerous to mention. (Chippewa Falls Chippewa Herald, WI)
'Junk' DNA Cut-and-paste Protein: Discovery May Prove Invaluable In Quest For Gene Therapies Sep 24, 2009
Learning more about transposition could help scientists understand how to control the process and speed the development of gene therapies which introduce into cells genes with beneficial properties that, for example, can fight hereditary diseases or cancer. Junk DNA, which accounts for almost half of the human genome, was originally believed to have no purpose. (Science Daily)
Weighing Pagliuca Sep 24, 2009
As for being qualified to be Kennedy s heir, the last time I checked we had a revolution some time ago to separate ourselves from a hereditary monarchy. Richard Chamberlain Beverly. (Boston Globe -- Editorial)
Targeted Heat Therapy Offers New Standard Treatment Option For Soft Tissue Sarcoma Sep 23, 2009
4, 2007) A study in the Jan. 3 issue of the Journal of the National Cancer Institute quantifies the risk of hereditary retinoblastoma survivors developing specific subtypes of soft tissue sarcomas and finds. (Nov. (Science Daily)
Checking Yourself Can Help Stop Cancer Sep 21, 2009
"Have a good mirror or a good friend or partner able to check your back," said Kathy Christiansen, the program manager for the Cancer Prevention and Hereditary Cancer Risk Program at Omaha's Methodist Hospital. "Look for any skin blemish that is not normal for you.". (KFOXTV.com, TX)
Gun control mainly about the control Sep 18, 2009
We cannot endure the infamy and guilt of resigning succeeding generations to that wretchedness which inevitably awaits them if we basely entail hereditary bondage on them. Thomas Jefferson, Declaration of the Causes and Necessities of Taking up Arms, 6 July 1775. (Mattoon Journal-Gazette, IL)
Gene therapy: An Interview with an Unfortunate Pioneer Sep 17, 2009
Philadelphia Ten years ago this month the promise of using normal genes to cure hereditary defects crashed and burned, as Jesse Gelsinger, an 18-year-old from Tucson, Ariz. succumbed to multiorgan failure during a gene therapy trial at the University of Pennsylvania. (Scientific American)
Scientists Cure Color Blindness In Monkeys Sep 17, 2009
About 1 in 30,000 Americans have a hereditary form of blindness called achromatopsia, which causes nearly complete color blindness and extremely poor central vision. "Those patients would be targets for almost exactly the same treatment," Hauswirth said. (Science Daily)
Wonder drug a true cancer-buster Sep 16, 2009
The type - olaparib - is already being used to treat some hereditary forms of breast cancer. It was developed by Professor Alan Ashworth and a British team from research charity Breakthrough Breast Cancer, reports The Sun. (India Times, India)
Epilepsy: The Cause and Effect Sep 14, 2009
Hereditary features are important in several of these seizures. Partial seizures start with an electrical discharge in one restricted area of the brain. (Suite101.com)
Public awareness focus of Sickle Cell month of recognition Sep 14, 2009
Today at 39, T-Boz has committed herself to educating others about the hereditary disease, while at the same time reminding people about the importance of living healthy lives. "I spent a lot of years not understanding my body," said T-Boz, who lives in Atlanta and is the national spokesperson for the Sickle Cell foundation. (Atlanta Journal-Constitution -- Metro)
Replication At DNA Damage Sites Highlights Fanconi Anemia And Breast Cancer Proteins Sep 12, 2009
11, 2009) While Fanconi anemia (FA) is a rare and dangerous disease, new laboratory research at The University of Texas M. D. Anderson Cancer Center shows it may lead researchers toward clues in more common diseases, including highly hereditary types of breast cancer ... People with FA, a hereditary disease, are extremely sensitive to DNA crosslinks and at a very high risk for cancer. (Science Daily)
Sleepless in Syracuse: Ways to battle insomnia Sep 11, 2009
03 percent of the general population could be diagnosed with narcolepsy, and it has been found to be hereditary. According to sleep-deprivation. (Daily Orange, NY)
North Korea's succession gets twisted Sep 11, 2009
Finally, one cannot rule out that Kim Jong-il does not want to continue with the tradition of hereditary rule at all. It is not as improbable as it sounds. (Asia Times Online)
Sudden Cardiac Death: Should Young Athletes Be Screened? Sep 11, 2009
Almost all cases of SCD occur in athletes with hereditary or congenital cardiovascular diseases like hypertrophic cardiomyopathy, a thickening of the heart. In 80% of cases, these diseases are asymptomatic and death occurs with little or no warning, almost always during or shortly after sport. (Time.com)
