Elevation Biotech and IAVI partner to develop next generation of HIV vaccines Oct 11, 2008
IAVI awards innovation grant to South African biotech company for the development and testing of new vaccine antigens that elicit broadly neutralizing antibodies against HIV. JOHANNESBURG, October 10, 2008 - Elevation Biotech, a start-up biotechnology company funded by LIFElab, an agency of the South African Department of Science and Technology, and the International AIDS Vaccine Initiative (IAVI), the world's only global non-profit organization dedicated solely to AIDS vaccine development, have... (EurekAlert! -- Business News)
Scripps Research Institute and IAVI launch world's first dedicated HIV neutralizing antibody center Oct 3, 2008
LA JOLLA, CA, and NEW YORK, NY, September 30, 2008 The Scripps Research Institute, one of the world's largest independent, non-profit biomedical research organizations, and the International AIDS Vaccine Initiative (IAVI), the world's only global non-profit organization focused solely on AIDS vaccine development, today announced the establishment of a new research center dedicated exclusively to solving the most pressing challenge facing AIDS vaccine researchers today ... "The world needs an... (EurekAlert! -- Business News)
HIV vaccine trial shows promising results Aug 18, 2008
Indian Council of Medical Research (ICMR), National AIDS Control Orgainsation (NACO) and International AIDS Vaccine Initiative (IAVI) said that the phase-1 of clinical trials of the AIDS vaccine has shown that it has suitable levels of safety and was well tolerated ... In Chennai the trial was conducted under the aegis of a MoU between the central government through ICMR and NACO and IAVI. YRG CARE, which was collaborated with TRC, helped increase the community during the trial of the phase I.. (TopNews)
India continues to progress in AIDS vaccine development efforts Aug 16, 2008
This trial was conducted under the aegis of a Memorandum of Understanding (MoU) between the Government of Indiathrough the Indian Council of Medical Research (ICMR) and the National AIDS Control Organization (NACO)and the not-for-profit International AIDS Vaccine Initiative (IAVI) ... Simultaneously, IAVI has undertaken work to modify the MVA-based vaccine candidate so that it is ready for large-scale manufacturing should the trial results suggest further testing is warranted ... The trial was... (EurekAlert!)
Encouraging results in initial trial offer hope for HIV Vaccine Aug 12, 2008
These medical trails are result of efforts of TRC, which is affiliated to the Indian Council of Medical Research (ICMR), the National AIDS Control Organisation (NACO) and the International AIDS Vaccine Initiative (IAVI) ... Dr. Sonali Kochar, Medical Director, IAVI India said that the Phase I trial of an MVA-based AIDS vaccine candidate (TBC-M4) was conducted at the TRC in Chennai. (TopNews)
Phase I prime-boost HIV vaccine trial planned Aug 11, 2008
CHENNAI: The International AIDS Vaccine Initiative (IAVI), a New York based organisation, along with the ICMR and NACO, is planning to conduct Phase I HIV prime-boost vaccine trials in Chennai and Pune. In a mail to this Correspondent in May this year, Dr. Seth Berkley, President and CEO of IAVI, New York had indicated a plan to start a prime-boost clinical trial in India. (Hindu)
Trial of anti-AIDS vaccine a success Aug 10, 2008
TRC is affiliated to the Indian Council of Medical Research (ICMR), which, along with National AIDS Control Organisation (NACO) and the International AIDS Vaccine Initiative (IAVI), has spearheaded the vaccine trial in India. "The Phase I trial of an MVA-based AIDS vaccine candidate (TBC - M4) was conducted at the TRC in Chennai. The preliminary results of the trial showed that the vaccine candidate was generally safe and well tolerated and the frequency of immune responses by volunteers after... (India Times, India)
New AIDS vaccine blueprint calls for more focus Aug 6, 2008
The group, known as IAVI, released a blueprint for how to proceed at an international meeting of AIDS experts and activists in Mexico City ... For instance, the IAVI blueprint notes it took 25 years to create a vaccine against the human papilloma virus or HPV, which causes cervical cancer, and there are still no vaccines against tuberculosis or malaria ... "Strong scientific evidence in both humans and animal models suggests that developing an AIDS vaccine is possible," said IAVI's Dr. Wayne... (AlertNet)
New Hope For HIV Vaccine: Unique HIV Vaccine Formula Elicits Strong Immune Responses May 24, 2008
In addition to NIH, the International AIDS Vaccine Initiative (IAVI) also provided funding support to part of the study. Researchers from Duke University Medical School also participated, as did Dr. Paul Goepfert at the University of Alabama-Birmingham. (Science Daily)
Leading HIV researchers to collaborate on vaccine development Apr 16, 2008
DURHAM, NC, and NEW YORK, NY Two global research organizations dedicated to designing a vaccine against HIV the International AIDS Vaccine Initiative (IAVI), and the Center for HIV/AIDS Vaccine Immunology (CHAVI) have signed an agreement to work together to address major biological questions that have slowed development of a safe, effective and affordable AIDS vaccine ... The work that will be done by IAVI, CHAVI and their networks of partners will rapidly enhance our understanding of HIV... (EurekAlert! -- Business News)
Researchers join forces for AIDS vaccine Apr 16, 2008
"Solving the HIV vaccine puzzle is a scientific challenge that can only be solved through fundamental and applied research, collaboration and transparency. The work that will be done by IAVI, CHAVI and their networks of partners will rapidly enhance our understanding of HIV and help lay the groundwork for new vaccine approaches," Dr. Barton Haynes, CHAVI director and professor of medicine at Duke University Medical Center, said in a prepared statement ... The global, not-for-profit IAVI works to... (News & Observer)
Putting Human Immunity in a Test Tube Mar 28, 2008
"In the end," says Wayne Koff, senior vice president of research and development at the International AIDS Vaccine Initiative (IAVI), "you can only extrapolate so much from a monkey model." ... IAVI's search for an answer led them to Florida ... Earlier this month, IAVI chose VaxDesign to receive the first award from its Innovation Fund, which supports potential breakthrough technologies applicable to AIDS vaccine research. (Time.com)
IAVI and VaxDesign partner to develop a clinical trial in a test tube for AIDS vaccines Mar 3, 2008
IAVI's Innovation Fund targets unconventional ideas for AIDS vaccine development. NEW YORK, March 3, 2008 The International AIDS Vaccine Initiative (IAVI) today announced the first award from its Innovation Fund, a new funding mechanism that will identify and advance potential breakthrough technologies and apply them in the AIDS vaccine research field ... IAVI will first test the technology on licensed vaccines for yellow fever and rabies to see whether the immune responses generated in vitro... (EurekAlert! -- Business News)
Study Shows How Some AIDS Vaccines May Harm Nov 20, 2007
The International AIDS Vaccine Initiative or IAVI used an adeno-associated virus in a trial of an AIDS vaccine that wrapped up in January in Belgium, Germany and India, and another in South Africa, Uganda and Zambia. IAVI's Pat Fast said the group was not testing AAV vaccines any more. (MEDLINEplus)
HIV Vaccine Not Effective, More Research Needed Nov 9, 2007
"It is also important to recognize that the failure of the Merck product to prevent HIV infection is not unexpected. Merck's candidate, like nearly all vaccine candidates now in the pipeline, was designed to activate the T-cell arm of the immune system. T-cells work like commando units, travelling through the body, seeking out pathogen-infected cells, which they then kill. Because T-cells only attack cells that are already infected, many scientists, including those at IAVI, think T-cell vaccines... (Science Daily)
Assessing a Failed AIDS Vaccine Nov 8, 2007
At the International AIDS Vaccine Initiative (IAVI), a non-profit group of public and private partners focused on funding and accelerating AIDS vaccine research, scientists are studying the use of crippled, live strains of HIV based on the success of other such live attenuated vaccines against polio and measles which they think might be critical to waking up the right immune system defenses. "There is something magical about the replicating virus, because it has virtually its entire genome,"... (Time.com)
Medical mystery's unravelling will aid research Sep 21, 2007
Compared with people in the West, Africans more commonly have parasites, or anemia, or some level of malaria exposure, which would cause them to test as unhealthy by the Western values even though they are well within the range of normal in their community, explained Pat Fast, the New York-based director of medical affairs for IAVI.. This does raise the question of whether the new reference ranges normalize conditions that are in fact the result of poor access to health care, a potential problem... (Globe and Mail)
AIDS Vaccine Field Moves Toward Larger-scale Efficacy Trials: Volunteers? Aug 24, 2007
Leading researchers from the International AIDS Vaccine Initiative (IAVI), the U.S. Centers for Disease Control and Prevention (CDC) and the U.S. Military HIV Research Program (USMHRP) presented final results from a collection of independent studies reexamining the medical criteria for including African volunteers in AIDS vaccine trials ... These studies are important for a range of research on neglected diseases, from HIV vaccines to malaria and TB drug therapy, said Anatoli Kamali, an... (Science Daily)
Multiple NIH Phase 2 HIV Vaccine Trials Using Vical's Technology Produce Encouraging Results Aug 23, 2007
"The latest International AIDS Vaccine Initiative (IAVI) listing of ongoing preventive HIV vaccine clinical trials shows that more than half use pDNA either alone or in combination with other vaccine modalities. We are very pleased that DNA technology is an integral part of the effort to address this high priority global health problem." The trials involved priming an immune response with three doses of a pDNA vaccine over a two month period, based on Vical's proprietary DNA technology, and... (PR Newswire)
Targeted Genetics Reports Interim Phase II Data From HIV/AIDS ... Aug 22, 2007
Targeted Genetics, the International AIDS Vaccine Initiative (IAVI), researchers at Columbus Children's Research Center and Children's Hospital of Philadelphia have collaborated on the development of tgAAC09 and other AAV-based HIV vaccines. In this double-blind, randomized, placebo-controlled study, 91 healthy HIV-negative volunteers at five clinical sites in Africa have received two intra-muscular injections of placebo or tgAAC09 at 3 different dosage levels either six or 12 months apart. (CNNMoney.com)
Health junket 'a mistake' Aug 6, 2007
Madlala-Routledge said she had been invited by the International Aids Vaccine Initiative (IAVI) to address their seminar on Aids vaccines scheduled for June 12 to 15. She told acting Health Minister at the time, Lulu Xingwana, she would be taking her son, Simon, an NGO activist, and Naidoo on the trip. (iAfrica.com)
Charlie Rose Science Series Episode #7 - July 24, 2007 Jul 24, 2007
A panel of leading experts will address factors which contribute to high infection rates, current treatment and prevention strategies, and new medical breakthroughs in fighting HIV/AIDS. WHO: Guests will include: - Seth Berkley, MD, President and Founder of the International AIDS Vaccine Initiative (IAVI) - Scott Hammer, MD, Chief of the Division of Infectious Diseases at the Columbia Presbyterian Medical Center - Peter Kwong, PhD, Chief of Structural Biology Section, Vaccine Research Center at... (Yahoo! Wire -- Entertainment News)
Japan's DNAVEC and IAVI partner on novel AIDS vaccine strategy Jul 10, 2007
New class of viral vector tapped to target primary site of HIV replication; Agreement marks IAVI's first product development partnership with Japanese company. Tsukuba City, Japan and New York, July 9, 2007The New York-based International AIDS Vaccine Initiative (IAVI) and DNAVEC Corporation today announced a collaboration to jointly develop an AIDS vaccine using DNAVEC's Sendai virus (SeV) vector technology ... "One of IAVI's scientific priorities is to develop vaccines by using new and... (EurekAlert! -- Business News)
Civil Society Leaders Announce New Global Call to Stop Cervical Cancer Jul 6, 2007
Editors note: Thirteen global civil society and public health organisations make up the strategic advisory committee for the Global Call to Stop Cervical Cancer: The World YWCA, The Rockefeller Foundation, PATH, The International Planned Parenthood Federation (IPPF), The International Federation of Gynecology and Obstetrics (FIGO), Family Care International, JHPIEGO, American Cancer Society, The AIDS Vaccine Advocacy Coalition (AVAC), The International AIDS Vaccine Initiative (IAVI), the Medical... (allAfrica.com)
Ten Years Later, AIDS Vaccine Search Continues May 22, 2007
"We have learned in that period of time how formidable an adversary HIV is," says immunologist Wayne Koff, senior vice president for research and development at the International AIDS Vaccine Initiative (IAVI) ... "By the early to mid- 1990s, the AIDS vaccine effort was relatively moribund," says IAVI president Seth Berkley, who founded the group in 1996 ... Global spending for HIV vaccine research increased from $186 million in 1997 to $759 million in 2005, according to the Joint United Nations... (Scientific American)
India, US body to jointly develop AIDS vaccine May 5, 2007
New Delhi, May 2 (IANS) India Wednesday signed an agreement with the US-based International AIDS Vaccine Initiative (IAVI) to develop an AIDS vaccine. According to the ministry of science and technology, its Department of Biotechnology (DBT) has tied up with IAVI to develop the vaccine ... The new Indian Medicinal Chemistry Programme, co-sponsored and co-funded by IAVI and DBT, will comprise top Indian and US scientists who will accelerate the pace of the AIDS vaccine discovery and develop... (Monsters and Critics.com)
India's DBT and IAVI forge partnership to develop 'next generation' vaccine candidates May 3, 2007
(NEW DELHI AND NEW YORK May 2, 2007) The Department of Biotechnology (DBT), Ministry of Science ology, Government of India and the International AIDS Vaccine Initiative (IAVI) signed an agreement today to address a major obstacle in AIDS vaccine development: the design of candidate vaccines to elicit neutralizing antibodies against HIV. A new Indian Medicinal Chemistry Programme, co-sponsored and co-funded by IAVI and the Department of Biotechnology, will comprise top Indian and U.S.... (EurekAlert! -- Business News)
Middle class volunteer for clinical trials Mar 19, 2007
Jean Louis Excler, the medical director of Iavi, said that all volunteers will be provided a general medical insurance cover for non-HIV events during the trial process, apart from other services like care and treatment ... Meanwhile, Iavi has tied up with Reliance Clinical Research Services, a subsidiary of Reliance Life Sciences, for the latters reputation in maintaining international standards on good manufacturing practices (GMP) ... The Iavi office in New Delhi has been invited by the... (India Times, India)
