Men's fertility decreases after 35, study confirms Jul 7, 2008
"And in ICSI [intracytoplasmic sperm injection], the best sperm can be selected for use. These methods, although not in themselves a guarantee of success, may help couples where the man is older to achieve a pregnancy more quickly and reduce the risk of miscarriage," Dr Belloc said. She followed 21,239 patients, and examined the sperm of each partner for count, motility and morphology. (Sydney Morning Herald -- Australia)
Couples with fertility problems where the man is over 35 have increased difficulty in conceiving Jul 7, 2008
"Our research proves for the first time that there is a strong paternal age-related effect on IUI outcomes, and this information should be considered by both doctors and patients in assisted reproduction programmes. "We believe that the use of IVF or ICSI should be suggested to infertile patients where either party is over 35 years of age. In IVF, the zona pellucida (the outer membrane of the egg) seems to be an efficient barrier in preventing the penetration of sperm with DNA damage, and in... (EurekAlert!)
Scientists warn that biological clock affects male fertility Jul 7, 2008
Those who fail to conceive after mild forms of fertility treatment, such as intrauterine insemination (IUI), in which sperm is washed and transferred directly into the uterus, should move quickly to more advanced treatments, such as ICSI, where the best quality sperm are picked out and injected directly into the woman's egg. The study looked at pregnancies and miscarriages recorded for couples having IUI treatment at the clinic between 2002 and 2006. (guardian.co.uk)
Sperm tablet fertile grounds for trial debate Jun 29, 2008
Lachlan Rothwell-Meehn, 40, took Menevit for three months before his wife, Belinda Brandt, 36, underwent intracytoplasmic sperm injection, a form of IVF, in an attempt to have a second child. It took years of IVF to become pregnant with their daughter Winter, but this time Ms Brandt became pregnant on her first cycle. (Sydney Morning Herald -- Australia)
Childless couples denied as anonymity loss Jun 27, 2008
It's the advent of a technology called ICSI that allowed some infertile men to conceive with their own sperm, so they no longer needed donors. That can't account for the more recent fall -- the switch from DI to ICSI for suitable patients had already happened, and the number of procedures was static at around 3,100 before the law was changed. (Times Online)
An unregulated nightmare Jun 24, 2008
For example, intracytoplasmic sperm injection artificially putting a spermatozoa into an egg has a higher incidence of complications in the offspring created. Likewise, a social revolution has occurred in which it has become politically incorrect to question the deliberate separation of genetic, gestational and social parenting. (Globe and Mail)
Oh Baby! Infertility treatment's high price tag prompts doctors to deliver new financing options Jun 5, 2008
Many IVF treatments also require another high-tech procedure called intracytoplasmic sperm injection (ICSI), in which a single sperm is mechanically inserted into a harvested egg in a lab before the embryo is implanted in the uterus. It is not uncommon for women or couples to end up spending $30,000 or more in their effort to have a baby. (St. Louis Business Journal, MO)
Biogenesis institute to expand a vision May 24, 2008
Yanagimachi and his colleagues developed the two key methods used worldwide to help people have babies: in-vitro fertilization, where the egg and sperm are joined outside the body, and intracytoplasmic sperm injection, where the sperm is injected into the egg by needle. Dr. Thomas Huang said he was an NIH researcher in Yanagimachi's laboratory from about 1981 to 1985 when Dr. Philip McNamee approached him about starting a fertilization clinic at Kapiolani Medical Center for Women ren. (Honolulu Star-Bulletin)
Fertility science giant honored May 22, 2008
Yanagimachi, who will be 80 on Aug. 27, did pioneering work on two major reproductive techniques -- in vitro fertilization where the egg and sperm are joined outside the body, and intracytoplasmic sperm injection where the sperm is injected by needle into the egg. Working with hamsters, Huang said, Yanagimachi and his group developed laboratory techniques "to lay the foundation for revolutionizing treatment of male infertility (half of all infertility cases) by injecting a single sperm into an... (Honolulu Star-Bulletin)
First Transgenic Monkey Model Of Huntington's Disease Developed May 20, 2008
Fertilizing the oocytes by intracytoplasmic sperm injection (ICSI); and. Transferring 30 embryos into eight surrogates. (Science Daily)
Now, a cheap IVF treatment that may fit into your lunch hour Apr 23, 2008
He also said that the procedure might be unsuitable for about 50 per cent of IVF patients who use intracytoplasmic sperm injection (ICSI), a technique to treat male infertility. He further said that performing such a procedure in an office setting would also be difficult due to regulatory issues. (TopNews)
Case of the disappearing dads Apr 10, 2008
In Australia and New Zealand in 2005, there were 21,420 assisted reproduction technology cycles in which an oocyte or embryo was transferred which involved ICSI - intracytoplasmic sperm injection ... In recent years, ICSI has outnumbered in-vitro fertilisation involving an oocyte or embryo transfer. (Sydney Morning Herald -- Australia)
Children of Sperm Donors Have Rights, Too Feb 20, 2008
Embryologist Harsha Bhadarka works on the Intra Cytoplasnic Sperm Injection (ICSI) process at Dr. Nayna Patel's Kaival Hospital in Anand, India, Monday, Dec. 17, 2007. The small clinic at Kaival Hospital matches infertile couples with local women, cares for the women during pregnancy and delivery, and counsels them afterward. (Townhall.com)
Significantly Higher Success Rates With Artificial Insemination Using New Ova Assessment Tool Feb 13, 2008
The microscopic procedure significantly improves the success rate of 'ICSI' (intracytoplasmic sperm injection) ... Up to now, the desire to have a child is only fulfilled for every third couple that decides to have ICSI. In a study the artificial insemination method was twice as successful ... For many couples ICSI is the last resort in their attempt to have a child. (Science Daily)
AIIMS pioneers in establishing first IVF Research Centre Feb 9, 2008
Single Hope Thus the only hope for such couples remains in the form of Assisted Reproductive techniques (ART) such as In Vitro Fertilisation (IVF) and Intra Cytoplasmic Sperm Injection (ICSI) ... IVF and ICSI involve inducing ovulation, monitoring egg development, procuring eggs from the woman's ovary, inseminating them with sperms, development, and growth of embryos, and subsequent transfer into the woman's womb. (Newstrack India)
World outsources pregnancies to India Dec 31, 2007
Embryologist Harsha Bhadarka works on the Intra Cytoplasnic Sperm Injection (ICSI) process at Dr. Nayna Patel's Kaival Hospital in Anand, India, Monday, Dec. 17, 2007. (Ajit Solanki / AP). (Albany Times Union)
Demand for IVF continues to rise Dec 7, 2007
UK's top 10 fertility clinics for live birth rate (women under 35 using their own fresh eggs for IVF and ICSI - intra cytoplasmic sperm injection) Assisted Reproduction and Gynaecology Centre London - 60. 7% Lister Fertility Clinic London - 43. (BBC News -- UK)
Baby Girl Born From Frozen Egg Nov 10, 2007
148 eggs survived the thawing and were fertilized using ICSI. 64 viable embryos were created, resulting in four successful pregnancies including that of the baby girl. Dr Hananel Holzer said. (Suite101.com)
A cheap, painless alternative to IVF? Oct 26, 2007
" Research on developing the culture medium in which the eggs are matured in the laboratory could reduce the attrition rate so that fewer eggs are needed. The technique could then become suitable for women with normal ovaries, Mr Child said. A second drawback of the procedure was that eggs grown in culture had a harder outer shell than those matured in the ovary and were more difficult for sperm to penetrate. The eggs had to be fertilised by ICSI injecting a single sperm directly into the egg.... (Independent)
Twins born after new fertility treatment Oct 25, 2007
They are then matured in a laboratory for up to 48 hours before being injected with a single sperm - a process called intracytoplasmic sperm injection (ICSI). A few days after fertilisation, the embryos are implanted into the mother's womb. (Guardian Unlimited)
Male Infertility Often Caused By Varicose Veins In The Scrotum, Simple Surgery Can Correct Oct 20, 2007
20, 2007) A national study reveals that intracytoplasmic sperm injection, an assisted reproductive technology used to treat male-factor infertility, has increased dramatically in the United States since 1995. (Nov. (Science Daily)
Fertility problems affect a third of couples Sep 5, 2007
Peter Bowen-Simpkins, a spokesman for the Royal College of Obstetricians and Gynaecologists, and director of the Cromwell IVF Clinic in Swansea, said, Fertility treatment has become a major way of solving the problem of infertility because it overcomes two of the things that cause it, including the male factor, through the introduction of ICSI.. And it can help women who are delaying pregnancy we are seeing more women coming in over the age of 35. (ic Wales)
Retrograde Ejaculation Aug 22, 2007
Common methods of assisted conception for men with this condition are: standard in vitro fertilisation, intracytoplasmic sperm injection (ICSI - which is usually done when there are only a few sperm available, and is when a single sperm is injected directly into the egg), and zygote intra fallopian transfer. This is when the egg is fertilised and the developing embryo is inserted into the fallopian tubes via a needle passed through the abdomen. (Suite101.com)
Building families Aug 22, 2007
Along with in vitro fertilization, the lab has intracytoplasmic sperm injection available, in which a single sperm cell is injected into an egg. Hill said this is good for men with low sperm count. (Odessa American, TX)
Ovarian Tissue Transplantation Works Despite Genetic Differences Aug 5, 2007
At one year, doctors retrieved two mature eggs from her and fertilized them with her husband's sperm using intracytoplasmic sperm injection because of his low sperm count. By 24 hours, one of the embryos had developed to the two-cell stage and the other to the three-cell stage. (MedPage Today)
First Case Of Successful Ovarian Tissue Transplantation Between Two, Nonidentical Sisters Aug 3, 2007
" Analysis of the sisters' HLA type showed that their genetically different cells coexisted successfully together (chimaerism) and that, therefore, no immuno-suppressive treatment would be required to prevent the ovarian graft being rejected. The earlier bone marrow transplant and resulting mixing of the sisters' cells meant that Teresa's immune system would recognise Sandra's ovarian tissue as "self" rather than "foreign".In February 2006, Teresa and Sandra were anaesthetised together and three... (Science Daily)
Sisters in historic ovarian tissue swap Aug 2, 2007
" The sisters underwent the operation to transfer the ovarian tissue in February last year. Sections of tissue were removed from Mrs Alvaro using laparoscopy and, in under a minute, were being sewn on to one of her sister's ovaries, also using laparoscopy. The sisters were discharged from hospital the next day. Mrs Alvaro's periods began six months later. Tests on her hormone levels confirmed that her ovaries were functioning. A year later, two eggs were removed from her ovary and fertilised... (The Herald)
Fertility method linked to low testosterone in boys Aug 1, 2007
NEW YORK (Reuters Health) - Levels of the male sex hormone testosterone in infant boys who are conceived using an assisted fertility technique called intracytoplasmic sperm injection (ICSI) are significantly lower than in their naturally conceived counterparts, according to Danish researchers. ICSI is the main method used to overcome male infertility. (Scientific American)
Study finds increased risks in IVF pregnancies Jul 27, 2007
The researchers led by Dr Alastair Sutcliffe, of the University College London, and Dr Michael Ludwig, Endokrinologikum in Hamburg, Germany reviewed data published between 1980 and 2005 on babies born by either IVF alone or by intracytoplasmic sperm injection (ICSI) and IVF, and used 3,980 articles to compile their analysis. They focused mainly on IVF single births, since multiple births can bring their own set of complications. (CTV.ca)
Sperm injection method may be used too much Jul 24, 2007
FERTILITY For many men with fertility problems, ICSI, or intracytoplasmic sperm injection, is a godsend ... But in recent years, ICSI has become standard practice in fertility clinics even when men have no sperm problems, according to a study by University of Illinois researchers ... By 2004, the study found, nearly 58 percent of in vitro fertilization procedures included ICSI, even though male infertility remained steady at about 30 percent. (Boston Globe)
Sperm banking before treatment preserves fertility in young male cancer patients Jul 23, 2007
Those who used their frozen sperm sample after overcoming their cancer had a fertility success rate of 36 percent using intrauterine insemination (IUI injecting the sperm into the uterus) and 50 percent using in vitro fertilization (IVF fertilizing the egg in a lab and then transferring the embryo to the uterus) and intracytoplasmic sperm injection (ICSI injecting the sperm directly into the egg). A vital component in the efficacy of the study was the collaborative approach taken by the... (EurekAlert!)
Sperm Injection: Male-factor Infertility Technique Surging Jul 21, 2007
A national study reveals that the use of intracytoplasmic sperm injection or ICSI -- an assisted reproductive technology used to treat male-factor infertility -- has increased dramatically in the United States since 1995, while the proportion of patients receiving treatment for male-factor infertility has remained stable. Rendering of a spermatozoon. (Science Daily)
Fertility Technique Common, Despite Doubts Jul 20, 2007
ICSI rates surging in U.S., but studies question its effectiveness, safety ... The team found that while the proportion of patients receiving treatment for male factor infertility has remained stable, the percentage of IVF cycles that used intracytoplasmic sperm injection (ICSI) increased from 11 percent to 57 ... "Despite its added cost and uncertain efficacy and risk, the use of ICSI has been extended to include patients without documented male-factor infertility," the study's lead author Dr.... (MEDLINEplus)
Trends in the Use of Intracytoplasmic Sperm Injection Jul 19, 2007
Background Intracytoplasmic sperm injection (ICSI) was initially developed as part of in vitro fertilization (IVF) to treat male-factor infertility. However, despite the added cost, uncertain efficacy, and potential risks of ICSI, its use has been extended to include some patients without documented male-factor infertility. (New England Journal of Medicine)
Is IVF Embryo Screening A Pregnancy Boost? Jul 7, 2007
In an editorial accompanying the study, John A. Collins, M.D., a physician at McMaster University in Hamilton, Ontario and Dalhousie University, Halifax, Nova Scotia, Canada, puts the results in perspective: "he results suggest that for every nine women who are 35 to 41 years of age who plan three cycles of IVF or IVF and intracytoplasmic sperm injection, there will be one more live birth if pre-implantation genetic diagnosis for [abnormalities] is not performed.". In an e-mail interview,... (CBS News)
Mice born from cloned sperm Jul 4, 2007
The researchers then fertilized intact mouse eggs with these cells, using a method called intracytoplasmic sperm injection. Already used in human in vitro fertilization, this involves using a fine needle to inject the sperm into the egg. (Nature News Service)
Germany's embryo protection law is 'killing embryos rather than protecting them' Jul 4, 2007
The data confirms that the proportion of ICSI to IVF procedures has continued to move in favour of ICSI, with 166,711 ICSI (intracytoplasmic sperm injection) procedures (60 per cent) versus 114,512 IVF (in vitro fertilisation) procedures (40 per cent) ... ICSI was the most common ART procedure (about 55 per cent of all ART procedures). (EurekAlert!)
First Baby Is Born After Oocytes Were Matured In The Lab And Frozen Jul 3, 2007
From these, 148 oocytes survived the thawing process and were fertilised via ICSI (intra-cytoplasmic sperm injection); 64 embryos were transferred to the women. More than one embryo was transferred to each patient because IVM is known to have lower rates of implantation. (Science Daily)
BBC Guide: IVF Jul 2, 2007
One of the biggest and most controversial advances in IVF in recent years has been the introduction of a technique called ICSI - intra-cytoplasmic sperm injection ... ICSI was introduced during the 1990s, but new advances are helping men with a very low sperm count to benefit from it. (BBC News -- Health)
Genetic Testing of Embryo Seen Safe for Offspring Jun 26, 2007
Couples who are at risk of certain genetic defects may choose to undergo assisted reproduction with PGD. In the procedure, a single sperm is injected into an egg (a technique called intracytoplasmic sperm injection, or ICSI) and then a cell or two is removed from the developing embryo to check for genetic problems. Embryos that are free of known defects are then transferred to the uterus. (MEDLINEplus)
Readers share theirfertility paths Jun 19, 2007
I did my IVF procedure with ICSI during that 5-week vacation. It resulted in a beautiful baby boy. (MSNBC -- Health)
Health Highlights: June 18, 2007 Jun 19, 2007
In the study, researchers at Brussels' Free University say that 563 of the 583 babies in the study that underwent PGD were born alive -- a rate that matches that of conventional IVF or another fertility procedure called ICSI, where sperm is injected into the egg. PGD babies also had comparable birth weights to infants who did not receive the procedure, and the rate of birth defects or malformations was also similar between PGD, IVF and ICSI children at two months and two years of age. (Forbes)
Gene screening 'safe' for babies Jun 17, 2007
These babies had a comparable birth weight to those born after conventional IVF treatment alone, and another fertility procedure called ICSI - where sperm is injected directly into an egg ... Lead researcher Professor Ingeborg Liebaers, from the Research Centre for Reproductive Genetics at the Universit Libre de Bruxelles, said: "We were encouraged to find that the major malformation rate was no higher than that which is found in children born after conventional IVF and ICSI." ... But she said... (BBC News)
Children born after PGD as healthy as those born after conventional IVF treatment Jun 17, 2007
Instead of carrying out a prenatal diagnosis followed by a termination of pregnancy, in vitro fertilisation (IVF) with intracytoplasmic sperm injection (where a sperm is injected directly into an egg) is performed, followed by genetic testing of the embryos. Only unaffected embryos are subsequently transferred to the womb. (EurekAlert!)
Sunny holidays 'hit sperm count' May 25, 2007
" Hot baths He said experiments had found that exposing the testes to heat over long periods led to a decreased sperm count. If this was a major effect, I think we would see people having problems conceiving in every country in the Tropics Dr Allan Pacey, University of Sheffield In the 1950s, it was even suggested that regular hot baths could be a successful contraceptive. Modern IVF methods do not require large numbers of viable sperm, as a single sperm can be used to fertilise an egg, in a... (BBC News -- Health)
Business in Brief (Tu) May 9, 2007
Johns Hopkins Hospital, in Baltimore, will open a fertility center May 12 at Green Spring Station in Lutherville, with a number of fertility treatments -- including in-vitro fertilization, intracytoplasmic sperm injection, gamete intrafallopian transfer, zygote intrafallopian transfer and donor egg-embryo and gestational carriers -- available. The in-vitro fertilization laboratory will be the only such lab in the mid-Atlantic region with an air filtration system to filter out benzene, according... (Towson Jeffersonian, MD)
The Fertility Maze: May 1, 2007
Along those same lines, Mundy focuses on growing questions about ICSI, the procedure in which sperm is injected into eggs. The Food and Drug Administration doesn't regulate ICSI, nor are there industrywide guidelines on counseling patients about it ... But when they use ICSI, that all changes. (Slate)
Everything Conceivable Apr 21, 2007
Within a decade, men with low sperm counts could father genetic offspring by means of ICSI, or intracytoplasmic sperm injection, a type of in vitro fertilization in which a sharpened pipette launches sperm into egg. A woman with aging eggs might gestate an embryo produced by her husband's sperm and a young donor's oocyte, thereby bearing his child - or children, since in vitro pregnancies often result in multiple births. (International Herald Tribune -- Arts)
News tips from the Journal of Biological Chemistry Apr 21, 2007
They blocked PAWP from functioning in sperm cells and then injected them in eggs with a common in vitro fertilization technique called intracytoplasmic sperm injection. Without PAWP, the sperm cells were unable to activate the eggs, confirming the proteins role in initiating the activation process. (EurekAlert!)
Regular IVF often best when only one egg available Apr 7, 2007
The choice is between intracytoplasmic sperm injection (ICSI), in which a single sperm is injected into the egg under a microscope, or conventional in vitro fertilization (IVF), which essentially places the egg with semen in a test tube. Dr. Jacob Levron from The Chaim Sheba Medical Center, Tel Hashomer. (Scientific American)
Womb transplant may replace surrogacy for infertile women Apr 6, 2007
Most cases can be treated by in vitro fertilisation (IVF) and sperm injection (ICSI). Yet for women who have healthy ovaries, but have had a hysterectomy or uterus problems, a transplant is their only hope of carrying a child. (Scotsman)
Safety Of Assisted Reproductive Technologies Studied Mar 5, 2007
Ryuzo Yanagimachi and Yukiko Yamazaki, University of Hawaii John A. Burns School of Medicine, and Lee Caperton, Alex McMahan and Christi Walter, UTHSC, compared mice produced by at least five different assisted reproductive technologies -- in vitro fertilization, embryo transfer, pre-implantation culture, intracytoplasmic sperm injection and round spermatid injection -- with mice produced by natural reproduction. The scientists reviewed the DNA of each group looking for "point mutations,"... (Science Daily)
Couples denied the chance of a baby in IVF postcode lottery Mar 2, 2007
He was shocked to discover that with NHS finances under serious pressure, some hospitals are refusing to fund IVF or other fertility techniques, including intracytoplasmic sperm injection (ICSI), in which a single sperm is injected directly into an egg. Because of apparently arbitrary age restrictions elsewhere, a woman living in one area could be considered too old to qualify while in another area she would be considered too young. (Daily Mail)
Steroid use fails to boost pregnancy rates in infertility treatments Mar 2, 2007
Intracytoplasmic sperm injection (ICSI) is another in vitro fertilization practice where a single sperm is injected directly into a harvested egg. The meta-analysis pooled data from 13 studies including 1,759 couples. (EurekAlert!)
Low fat dairy foods may increase infertility risk Mar 1, 2007
- Provides extensive infertility information including: in vitro fertilization (IVF), ICSI, infertility clinics, donor egg and surrogacy programs. - Infertility can be due to many causes. (SpiritIndia)
In vitro not risky, study finds Feb 27, 2007
The researchers compared mice produced using natural reproduction to those produced through in-vitro fertilization, embryo transfer, pre-implantation culture, intracytoplasmic sperm injection and spermatid (a round sperm with no tail) injection. They used the latest techniques and "special" mice that were genetically manipulated to examine the DNA of each group, Yanagimachi said. (Honolulu Star-Bulletin)
Eating trans fats may increase infertility risk Jan 22, 2007
- Provides extensive infertility information including: in vitro fertilization (IVF), ICSI, infertility clinics, donor egg and surrogacy programs. - Infertility diagnosis and treatment, including Clomid, IVF and egg donation. (SpiritIndia)
My IVF and the clinic from hell Jan 16, 2007
Having looked at the report from our GP and asked how long we had been trying to get pregnant, he recommended ICSI - intra cytoplasmic sperm injection - a type of IVF where the best sperm is isolated and injected directly into the egg ... " Trust is something one should be able to take for granted when undergoing any medical treatment, though it was in short supply among patients at the ARGC. Many I spoke to - some on their third or fourth cycles - had begun to question the blood tests (costing... (Independent)
Young single men are more likely to bank sperm before testicular cancer treatment Jan 9, 2007
"Revolutionary techniques such as in vitro fertilisation and intracytoplasmic sperm injection make pregnancy possible with even the lowest quality of sperm. "However, up to a quarter of men don't produce usable sperm after treatment. "These factors probably explain why most urologists, radiation oncologists and medical oncologists offer sperm banking before therapy for testicular cancer. "However, our survey shows that sperm banking costs are relatively high and usage is relatively low. (EurekAlert!)
