Molecular Pathway Appears Crucial In Development Of Pulmonary Fibrosis Dec 15, 2007
14, 2007) A study led by Massachusetts General Hospital (MGH) researchers may have found a key mechanism underlying idiopathic pulmonary fibrosis (IPF), a usually fatal lung disease for which transplantation is the only successful treatment ... 16, 2006) For idiopathic pulmonary fibrosis patients awaiting lung transplantation, a simple walk test can predict mortality rates. (Science Daily)
‘His final jump': Thousands celebrate Butte daredevil's life Dec 11, 2007
When he died Nov. 30 at the age of 69, it was from idiopathic pulmonary fibrosis, a scarring of the lungs. Son Robbie Knievel, who followed in his father's daredevil footsteps and who was estranged from Evel for many years, thanked his father's latest ex-wife, Krystal Kennedy-Knievel, for staying by his father's side throughout his health problems, even after they divorced in 2001. (Missoulian, MT)
Sunday’s fireworks have multiple purpose Dec 8, 2007
Olson hopes to use the event to raise money to fight the disease that killed Butte s daredevil idiopathic pulmonary fibrosis. Olson and his team will be at the Butte Civic Center Saturday morning to begin taking donations. (Montana Standard, MT)
I will miss this star-spangled daredevil Dec 4, 2007
"This is Billy Rundle, commenting on the tragic demise of his close friend Evel Knievel, called "the ultimate American Daredevil" by the Smithsonian Institution. Knievel, who suffered from diabetes and idiopathic pulmonary fibrosis, died Friday in his Clearwater, Fla. The full text of this article has 895 words. To continue reading this article, you must be a subscriber or a subscriber. Already have a member account? Product Tour Take a look around with a virtual tour To view the tour, you will... (Globe and Mail -- Entertainment)
Daredevil lived to cheat death Dec 3, 2007
In recent years, he had suffered from diabetes and idiopathic pulmonary fibrosis, an incurable lung condition. Honoured with an exhibit in Washington's Smithsonian Institution dubbing him "America's Legendary Daredevil," Knievel most famous stunt was in September 1974 when he tried, but failed, to jump over the Snake River Canyon in Idaho using a rocket-powered motorcycle. (Toronto Star)
Last ride for Evel Knievel, man of steel and scars Dec 2, 2007
Knievel had been in failing health for years with diabetes and idiopathic pulmonary fibrosis, an incurable lung condition. In 1999 he underwent a liver transplant after nearly dying of hepatitis C, which he believed he had contracted through a blood transfusion after one of many violent spills. (The Age)
Evel Knievel Lost to Pulmonary Fibrosis; Disease Claims as Many Lives as Breast Cancer Each Year Dec 1, 2007
Knievel was unfortunately one of 40,000 people in the U.S. who will lose their lives to idiopathic pulmonary fibrosis (IPF) this year, the same number as will die from breast cancer ... About Idiopathic Pulmonary Fibrosis (IPF) IPF is a lung disorder characterized by a progressive scarring - known as fibrosis - and deterioration of the lungs, which slowly robs its victims of their ability to breathe ... About the Coalition for Pulmonary Fibrosis The Coalition for Pulmonary Fibrosis (CPF) is a... (PR Newswire)
Robert `Evel' Knievel, Motorcycle Daredevil, Stuntman, Is Dead at Age 69 Dec 1, 2007
He suffered from diabetes and idiopathic pulmonary fibrosis, an incurable lung condition, the Associated Press said. He also had a liver transplant in 1999 after he almost died from hepatitis C, a disease that he likely got through a blood transfusion, the news service reported. (Bloomberg -- US)
Preventing Lung Scarring May Extend Lives Of Lung Cancer Patients Nov 1, 2007
13, 2007) Researchers have found that Viagra may help patients with idiopathic pulmonary fibrosis, an incurable disease characterized by progressive scarring in the lungs, which often leads to a lung. (Oct. (Science Daily)
Hui Yee gets a new heart Oct 5, 2007
The IJN transplant team, headed by chief cardiothoracic surgeon Datuk Dr Mohd Azhari Yakub and Heart and Lung Transplant clinical director Dr Mohamed Ezani Md Taib performed the surgery simultaneously with another double lung transplant on a 39-year-old man suffering from idiopathic pulmonary fibrosis (lung failure). Six cardiothoracic surgeons, six anaesthetists, one physician from the Respiratory Research Institute and 30 paramedics were involved in the surgeries. (The Star Online, Malaysia -- News)
Evel Knievel Days (30) Jul 15, 2007
Evel Knievel suffers from idiopathic pulmonary fibrosis, a condition that scars the lungs, replacing the air sacs with scar tissue. On the Net: For a detailed listing of Evel Knievel Days events, visit www. (Montana Standard, MT)
Walker in swing of things Jun 16, 2007
Walker's health she has idiopathic pulmonary fibrosis has sent the couple to the lower altitude of southern Utah. But two or three times a month they drive up to Salt Lake City for one of her many meetings. (Deseret News)
Hamsters on Viagra Experience Less Jet Lag, Scientists in Buenos Aires Say May 22, 2007
Another study recently showed that the drug may help in treating idiopathic pulmonary fibrosis. Viagra keeps another chemical in the brain, called cyclic GMP, from decomposing. (Bloomberg -- Latin America)
Webcast Alert: CPF 'Living with IPF' Patient Seminar to be Webcast Live May 12, 2007 May 9, 2007
May 8 /PRNewswire/ -- The Coalition for Pulmonary Fibrosis (CPF), a California based nonprofit organization, and The Mount Sinai Medical Center (New York, NY), one of leading specialty centers for the treatment and study of pulmonary fibrosis, will hold a live audio Webcast for patients and families living with idiopathic pulmonary fibrosis, members of the public, and members of the media. The "Living with IPF" patient seminar will be held Saturday, May 12, 2007 from 12:50 - 5:30 P.M. EDT, and... (PR Newswire)
Pulmonary Fibrosis Patient, CPF Member & Advocate, on 'The View' Apr 29, 2007
April 27 /PRNewswire/ -- Today, Vito Valenti spoke to "The View" hosts Rosie O'Donnell and Joy Behar about his personal struggle to survive idiopathic pulmonary fibrosis (IPF) ... Key Facts About Idiopathic Pulmonary Fibrosis (IPF) ... Definition: Idiopathic Pulmonary Fibrosis (IPF) is defined as a progressive and ultimately fatal scarring process in the lungs of unknown cause. (Yahoo! Wire -- Entertainment News)
Actelion Announces First Quarter Results 2007 Apr 19, 2007
7 m), in-line with the start of new pre-clinical and clinical programs, such as the BUILD-3 pivotal study to evaluate the safety and efficacy of bosentan in patients suffering from idiopathic pulmonary fibrosis (IPF) and accelerated recruitment into the Phase II program with the orexin receptor antagonist. In Q1 2007, marketing and advertising costs were CHF 52. (Primezone Releases)
Respiratory Care Leadership Expresses Patient Access to Quality Care Concerns Over CMS Final Rule on Competitive Bidding for Home Oxygen Therapy Apr 6, 2007
Peter Kelly, Chairman of the CQRC and CEO of Pacific Pulmonary Services, said, "The Medicare home oxygen benefit provides home oxygen therapy for patients suffering from Chronic Obstructive Pulmonary Disease (COPD), which is regarded as the fourth leading cause of death in the United States. Under this Final Rule, lower quality standards than what the CQRC supports, coupled with a bid structure that is designed solely to minimize upfront costs, induces providers to sacrifice service levels and... (PR Newswire)
Gene Mutations Linked To Hereditary Lung Disease Mar 30, 2007
A progressive scarring of the lungs with no effective treatment, idiopathic pulmonary fibrosis (IPF) affects approximately 50,000 Americans annually, and like some cancers often is fatal within three years ... Citation: Armanios, MY, et al. Telomerase Mutations in Families with Idiopathic Pulmonary Fibrosis. (Science Daily)
Parsing Pulmonary Fibrosis Mar 29, 2007
NEJM -- Idiopathic Pulmonary Fibrosis -- New Insights ... Idiopathic Pulmonary Fibrosis New Insights ... "Death occurred about three months and a half after the onset of the acute disease and the lung was two thirds of the normal size, grayish in color, and hard as cartilage. Microscopically these areas showed advanced fibrotic changes and great thickening of the alveolar walls." Thus did Sir William Osler describe, in 1892, a case of idiopathic pulmonary fibrosis1 an unrelenting and progressive... (New England Journal of Medicine)
Mutant Telomerase in Familial Idiopathic Pulmonary Fibrosis Mar 29, 2007
NEJM -- Telomerase Mutations in Families with Idiopathic Pulmonary Fibrosis ... Telomerase Mutations in Families with Idiopathic Pulmonary Fibrosis ... Background Idiopathic pulmonary fibrosis is progressive and often fatal; causes of familial clustering of the disease are unknown. (New England Journal of Medicine)
InterMune asks for more time to file 10-K Mar 16, 2007
The biotech company said earlier this month it would stop trials of the drug, which was designed for the potential treatment of patients with idiopathic pulmonary fibrosis. Extra. (San Jose Business Journal, CA)
Viagra Drug May Help Improve Exercise Capacity In Pulmonary Fibrosis Patients Mar 14, 2007
UCLA researchers have found that Viagra may help patients with idiopathic pulmonary fibrosis, an incurable disease characterized by progressive scarring in the lungs, which often leads to a lung transplant ... In this pilot study, 14 idiopathic pulmonary fibrosis patients initially took a standard six-minute walking test. (Science Daily)
InterMune stock down 22% after drug trial halt Mar 7, 2007
s stock dropped 22 percent Tuesday after the company announced a day earlier that it was discontinuing clinical trials of a drug designed for patients with idiopathic pulmonary fibrosis. The stock closed the day at $22. (San Jose Business Journal, CA)
InterMune Plummets After Halting Key Trial Mar 7, 2007
-based company halted late stage trials of a treatment for the lung condition idiopathic pulmonary fibrosis. Data from the Phase III clinical trial showed that the drug did not show a statistically significant improvement in mortality rates over a placebo for the disease. (BusinessWeek)
Tuesday's Stocks to Watch Mar 6, 2007
InterMune Inc. () said it has discontinued its Phase III clinical trial evaluating Actimmune in patients with idiopathic pulmonary fibrosis, based upon the recommendation of the study's independent data monitoring committee. In a planned interim analysis that included a total of 115 deaths, the committee found the overall survival result crossed a predefined stopping boundary for lack of benefit of Actimmune relative to placebo. (Fox News)
InterMune stops Phase III trial Mar 6, 2007
said Monday it stopped a Phase III clinical trial of the drug actimmune because it failed to prolong the survival of patients with idiopathic pulmonary fibrosis ... InterMune is also testing another treatment for idiopathic pulmonary fibrosis, a lung disease. (San Francisco Business Times, CA)
Charlie Norwood: Conservative Champion Feb 20, 2007
Norwood had also battled idiopathic pulmonary fibrosis (IPF) for years, being diagnosed with the condition in 1998 and receiving a lung transplant in 2004 as treatment. A member of the 1994 Republican Revolution, the 65-year-old congressman worked tirelessly on several issues of importance both to his state and to the nation. (Human Events Online)
Charlie Norwood Feb 15, 2007
at the age of 65 after a long battle with lung cancer and idiopathic pulmonary fibrosis. As a member of the Republican Revolution, Mr. Norwood was often found at the forefront of fights to reform Washington, such as the investigation into the Teamsters and the investigation into fraud and theft at the Department of Education. (Washington Times, DC)
Rep. Charles Norwood Dies At 65 Feb 14, 2007
Thirty years later, Norwood was diagnosed with idiopathic pulmonary fibrosis, which began restricting his ability to breathe and ultimately required a lung transplant in 2004. After the surgery, he used oxygen and zipped around the Capitol in a motorized cart, earning a reputation for having a lead foot. (CBS News)
U.S. Rep. Charlie Norwood succumbs to cancer | Political Insider Feb 14, 2007
Charlie Norwood (R-GA10), 65, passed away this morning at his Augusta home following an extensive battle with idiopathic pulmonary fibrosis (IPF) and non-small cell lung cancer. Norwood received a single lung transplant in 2004 as treatment for IPF, and developed non-small cell lung cancer in 2005. (Atlanta Journal-Constitution -- Opinion)
Congressman Norwood dies of cancer Feb 14, 2007
Charlie Norwood (R-Augusta) died Tuesday after an eight-year fight with idiopathic pulmonary fibrosis (IPF). The 65-year-old, seven-term congressman had a single lung transplant at Inova Fairfax Hospital in Fairfax, Va. (Atlanta Business Chronicle, GA)
Norwood dies at age 65 Feb 14, 2007
Norwood had been ill since 1998, when he was diagnosed with idiopathic pulmonary fibrosis, a chronic lung disease. He received a single lung transplant in 2004. (Athens Banner-Herald)
GOP's Norwood dies of lung disease, ... (Christina Bellantoni) Feb 14, 2007
"He was a great man who came here for the right reasons." The House interrupted Iraq debate for a moment of silence in honor of Mr. Norwood, who fought idiopathic pulmonary fibrosis for eight years. In 2004, he received a lung transplant, and later developed lung cancer, a common side effect of drugs prescribed for the transplant. (Washington Times, DC)
Read Janis Fontaine's blog Feb 9, 2007
Linde had been battling idiopathic pulmonary fibrosis, a lung disease. Posted by Janis Fontaine at. (The Palm Beach Post)
Georgia lawmaker to go home for hospice care Feb 8, 2007
He suffers from idiopathic pulmonary fibrosis, a chronic lung disease. Last year, doctors discovered a small cancerous tumor on his non-transplanted lung. (Washington Times, DC)
Breakthrough Could Prevent Multiple Fibrotic Diseases: Tests Find Protein Stops Fibrosis In Lung, Heart, Other Tissues Jan 20, 2007
(November 16, 2004) -- Mayo Clinic researchers have identified a treatment for the fatal lung disease idiopathic pulmonary fibrosis (IPF) ... (January 24, 2005) -- Every breath soon turns into a struggle for people living with idiopathic pulmonary fibrosis (IPF). (Science Daily)
Dick Simmons: A 'passion' for the Pittsburgh Symphony Orchestra Jan 14, 2007
" Being in the right place at the right time -- that, Dick Simmons says, has happened to him his entire life: Born during the Depression but too late to serve in World War II. Being an expert in titanium steel, which would be a boon to the specialty steel industry. Taking his company public just five months before the October 1987 stock market crash. But it was being in the right place at the wrong time that drives the third act in Mr. Simmons' story, when he became the millionaire savior to the... (Pittsburgh Post-Gazette, PA)
Georgia Rep. Norwood Could Miss More Work Battling Cancer Jan 13, 2007
He suffers from idiopathic pulmonary fibrosis, a chronic lung disease that required the transplant. Last year, doctors discovered a small cancerous tumor on his non-transplanted lung. (Fox News -- Politics)
* World News Quick Take Jan 2, 2007
The cause was idiopathic pulmonary fibrosis, a lung disease, family members told the Tennessean newspaper. Burning Love reached No. 2 on the Billboard pop listings and was Presley's second-highest-charting single in a decade. (Taipei Times, Taiwan -- World)
Shionogi Reports Results of Phase III Clinical Trials of the Idiopathic Pulmonary Fibrosis Treatment S-7701 Dec 26, 2006
Tokyo, Dec 26, 2006 (JCN) - Shionogi announced on December 22 that it has achieved the primary objectives of Phase III clinical trials for the idiopathic pulmonary fibrosis treatment S-7701, generic name pirfenidone, which the Company is developing in Japan under a license from U.S.-based Marnac, Inc. and KDL, Inc., Tokyo. Idiopathic pulmonary fibrosis (IPF) is a medical condition of unknown etiology with poor prognosis in which progressive fibrosis of the alveolar walls produces irreversible... (JCN Network, Japan)
Evel Knievel vs. "Kanyevel" Dec 14, 2006
Aside from enduring dozens of broken bones from stunt mishaps and suffering from hepatitis C, which required a liver transplant, the elder Knievel announced in July he was battling the incurable lung disease idiopathic pulmonary fibrosis and requires supplemental oxygen around the clock. Knievel's Tampa-based attorney, Richard Fee, was out of the office and unavailable for comment Tuesday. (E! Online)
Evel Knievel Sues Rapper Kanye West for Jumpsuit Likeness Dec 14, 2006
n July 27, 2006, on The Adam Carolla Show, Knievel said that he has idiopathic pulmonary fibrosis, and requires supplemental oxygen 24 hours a day. The complaint was published online by the. (Playfuls.com)
Rep. Norwood released from hospital Dec 9, 2006
He received the new lung because of idiopathic pulmonary fibrosis, a progressive hardening of the lung tissue. A side effect of the drugs he takes to suppress his immune response and prevent rejection of the new organ is the development of cancerous tumors. (Atlanta Journal-Constitution -- Metro)
Rep. Norwood back in hospital Dec 6, 2006
Norwood received his lung transplant to combat the effects of idiopathic pulmonary fibrosis, a progressive disease that results in the hardening of lung tissue. The press release said cancer is a frequent side effect of the immune suppression drugs Norwood must take to prevent his body from rejecting the new lung. (Atlanta Journal-Constitution)
A tribute to a lifelong dog lover Nov 16, 2006
Idiopathic pulmonary fibrosis destroyed her lungs but never destroyed her will to live. Friends and relatives gathered Saturday, not to mourn her death but to celebrate her life. (Pittsburgh Post-Gazette, PA)
Proteins may predict lung transplant rejection Nov 4, 2006
Lung transplants are a common therapy for many end-stage lung diseases such as chronic obstructive pulmonary disease, cystic fibrosis, pulmonary hypertension, idiopathic pulmonary fibrosis and other diseases. Patients who receive a new lung may suffer bouts of acute or chronic rejection. (EurekAlert!)
Biotech company to settle U.S. probe Oct 28, 2006
But prosecutors accused InterMune of also promoting it in 2002 and early 2003 as useful for patients with idiopathic pulmonary fibrosis, or IPF, a potentially fatal lung disease for which there is no federally approved treatment. Despite a study showing Actimmune failed to help keep IPF patients alive, prosecutors alleged, InterMune put out a news release in 2002 claiming the drug had improved the patients' chances of survival. (San Jose Mercury News -- Business)
InterMune to pay $37M to settle federal charges Oct 27, 2006
The company was accused of fraudulent and misleading marketing of Actimmune7 for the treatment of idiopathic pulmonary fibrosis. Actimmune7 has not been approved for the condition by the Food and Drug Administration. (San Francisco Business Journal)
Drugmaker paying $37 million for off-label marketing Oct 27, 2006
The drug Actimmune is approved by the Food and Drug Administration to treat an immune system disorder and a bone disease but was often prescribed off-label to treat a lung-scarring condition known as Idiopathic Pulmonary Fibrosis. Federal authorities said the vast majority of Actimmune sales between August 2002 and January 2003 were for treating IPF, a disease afflicting 83,000 Americans in which there is no FDA-approved treatment. (San Diego Union-Tribune -- Business)
InterMune to Present at the C.E. Unterberg, Towbin Life Sciences Conference Oct 26, 2006
InterMune has a pipeline portfolio addressing idiopathic pulmonary fibrosis (IPF) and hepatitis C virus (HCV) infections. The pulmonology portfolio includes two Phase III programs evaluating possible therapeutic candidates for treatment of patients with IPF. The INSPIRE trial is evaluating Actimmune(R) and the CAPACITY program is evaluating pirfenidone. (PR Newswire)
Antioxidant Protects Against Lung Damage In Silicosis Oct 17, 2006
(September 16, 2006) -- For idiopathic pulmonary fibrosis patients awaiting lung transplantation, a simple walk test can predict mortality rates. A new study found that individuals with IPF who cover less than 680 feet. (Science Daily)
Pulmonary Fibrosis Prevalence Increases 156 Percent in Six Years Oct 6, 2006
Idiopathic pulmonary fibrosis (IPF) is the deadliest form of pulmonary fibrosis and is a progressive and ultimately fatal lung disease ... "Based on increased awareness in the entities of idiopathic interstitial pneumonia among pulmonologists, the true incidence and prevalence of idiopathic pulmonary fibrosis and interstitial pneumonias is likely to be significantly higher than this study suggests. Increased funding for research is desperately needed to identify new approaches to understanding... (PR Newswire)
News in brief from western Pennsylvania Oct 4, 2006
Researchers will also be looking to improve the treatment and diagnosis of patients with idiopathic pulmonary fibrosis, a progressive scarring of the lung that affects more than 100,000 people in the United States. Read our. (NEPA News, PA)
Walking Test Spots Sickest Lung Transplant Candidates Sep 19, 2006
In the Sept. 15 issue of the American Journal of Respiratory and Critical Care Medicine, researchers from Columbia University examined the medical records of 454 people with idiopathic pulmonary fibrosis (IPF), all of who were on a lung transplantation waiting list. IPF is a lung disease in which lung tissue is damaged by an unknown cause. (MEDLINEplus)
Shorter distance on six-minute walk test points up a greater risk of death Sep 16, 2006
For idiopathic pulmonary fibrosis (IPF) patients awaiting lung transplantation, a simple walk test can predict mortality rates. A new study found that individuals with IPF who can cover less than 680 feet during the six-minute test are four times more likely to die than those who can walk greater distances. (EurekAlert!)
Biotech firm seeks to resolve probe Jul 29, 2006
Welch said Intermune settled Gallagher's suit for an undisclosed amount. In 2005, the company also settled a group of shareholders' suits related to its marketing practices for about $10 million. (San Francisco Chronicle)
Actelion Announces Half Year Financial Results 2006 Jul 20, 2006
-- At the American Thoracic Society (ATS) conference in May 2006, Actelion presented findings from the BUILD-1 study in patients with biopsy-proven idiopathic pulmonary fibrosis. Based on this data, the company is preparing BUILD-3, a morbidity/mortality study in patients with idiopathic pulmonary fibrosis. (Primezone Releases)
Losing never felt so good Jul 13, 2006
That Parker could even be shooting baskets or putting on Nikes seemed out of the question less than two years ago when doctors diagnosed him with idiopathic pulmonary fibrosis, a disease that scars lung tissue and diminishes their ability to transfer oxygen into the bloodstream. The prognosis was six months, maybe a year, to live without a lung transplant. (Lawrenceburg Anderson News, KY)
A candidate gene for familial idiopathic pulmonary fibrosis identified Jun 29, 2006
ELMOD2-gene is a prime candidate gene for familial idiopathic pulmonary fibrosis, suggests the recent study published by the researchers at the University and University Hospital of Helsinki, Finland. Idiopathic pulmonary fibrosis (IPF) is a chronic, late-onset disease of lung parenchyma with unknown etiology ... In their previous studies researchers at the University of Helsinki and the University Hospital of Helsinki observed that the prevalence of idiopathic pulmonary fibrosis distributed... (EurekAlert!)
Wife honors late husband's wish in 'warm autopsy program' Jun 14, 2006
A lung biopsy showed that he had idiopathic pulmonary fibrosis, in which the lungs become scarred. The cause is not known. (Pittsburgh Post-Gazette, PA)
Herbert Henderson Larsen Jun 8, 2006
He went to be with his Savior on Friday, May 26, 2006 at St. Luke s Regional Medical Center from complications related to Idiopathic Pulmonary Fibrosis. Herb was a devoted husband, father, grandfather and friend. (Emmett Messenger Index, ID)
Irene George, 71, never forgot her native Greece Jun 3, 2006
" Mrs. George, 71, of Cumming died Monday of idiopathic pulmonary fibrosis at Peachtree Christian Hospice. The funeral is 1 p.m. today at the Greek Orthodox Cathedral of the Annunciation. H.M. Patterson Oglethorpe Hill, is in charge of arrangements. Mrs. George could easily be forgiven for her love of Greece. At 20, she left behind her large family there to enroll in Baltimore's Mount St. Agnes College now Loyola University where she graduated in 1958. Her homesickness was so fierce at first... (Atlanta Journal-Constitution -- Metro)
Read more... May 9, 2006
She lost her 10 years ago to an incurable lung disease called idiopathic pulmonary fibrosis (IPF); the same disease threatens her own life today. Today, though there are still no FDA approved treatments, no known cause and no cure, there is promising new research as well as a patient-centered non-profit organization called the that joins Joy in her fight. (PNN Online)
Brushes with death fail to curb Norwood's pace May 5, 2006
Doctors said at the time that most patients with idiopathic pulmonary fibrosis, the hardening of lung tissue, often don't live more than five years without a transplant. A year later, in November 2005, Norwood was back in the hospital. (Atlanta Journal-Constitution)
Research Provides Promising Evidence Of New Drug Therapies In Lethal Lung Disease Apr 10, 2006
(January 24, 2005) -- Every breath soon turns into a struggle for people living with idiopathic pulmonary fibrosis (IPF). Lung transplantation has been the only definite treatment option for this progressive disease with. (Science Daily)
