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    News and Articles on Immune response

    Archives: Immune response

    DNA-based Vaccine Shows Promise Against Avian Flu  Oct 6, 2008
    Such a vaccine, which consists of plasmid DNA that s been genetically modified to elicit specific immune responses, is much easier to rapidly modify and produce critical advantages when racing to prevent an epidemic ... The immune responses directed to our DNA vaccine seem to be very broad, Ho says ... The vaccine produced a strong immune response in mice and protected them from death. (Science Daily)

    Scientists 'See' How HIV Matures Into An Infection  Oct 4, 2008
    17, 2007) Natural HIV-1 infection does not always elicit a protective immune response, according to a new study in PLoS Pathogens. The team of researchers show how HIV-1 vaccines may not be as reliable against. (Science Daily)

    BioMS Medical's phase III U.S. multiple sclerosis trial receives positive safety review from Data Safety Monitoring Board  Oct 3, 2008
    The primary clinical endpoint for the trial is defined as a statistically and clinically significant increase in the time to progression of the disease as measured by the Expanded Disability Status Scale (EDSS), in patients with HLA-DR2 and/or HLA-DR4 immune response genes (up to 75% of all MS patients are HLA-DR2 and/or HLA-DR4 positive). BioMS Medical is a biotechnology company engaged in the development and commercialization of novel therapeutic technologies. (Canada Newswire)

    Changing Dosing, Administration Of Anthrax Vaccine Reduces Side Effects  Oct 3, 2008
    13, 2006) Microneedle-based vaccination with the current anthrax vaccine produced an equally effective immune response to intramuscular injection in rabbits using smaller dosage say researcher from Maryland. (Aug. (Science Daily)

    New Way To Make Malaria Medicine Also First Step In Finding New Antibiotics  Oct 3, 2008
    9, 2006) A weakened immune response resulting from HIV infection can lead to trouble when it comes to treating malaria, according to a new study appearing in the Oct. 1 issue of the Journal of Infectious. (May 23, 2007) Ugandan children who received the combination therapy of artemether-lumefantrine experienced a lower rate of treatment failure compared to other combination therapies, according to a recent. (Science Daily)

    Studies Ignite Hope for Long-Acting Allergy Vaccines  Oct 3, 2008
    Allergy vaccines are highly effective but have certain drawbacks, allergists say, including the number of shots required to build up an immune response. "It takes between six and 18 months of weekly injections to reach the maximum effect, so people are coming in every week, and they get an injection," Howland explained. (MEDLINEplus)

    Compounds That Prevent Nerve Damage Discovered  Sep 25, 2008
    (July 16, 2008) The damage to brain tissue seen in Huntington's disease may be caused by an overactive immune response in the bloodstream and the brain. Working separately, two teams found evidence in both brain. (Science Daily)

    Dynavax gets $4.5 million payment  Sep 23, 2008
    The drug, AZD1419, changes the body s immune response to particular allergens. Berkeley-based Dynavax stands to receive a total of $136 million while the drug is being developed, plus royalties if it is successful and goes on sale. (San Francisco Business Times, CA)

    Laugh your way to peace, better health  Sep 23, 2008
    "Laughter improves our immune response, enhances respiration, stimulates blood flow and raises our pain threshold.... Those effects help make us healthier and happier. That happy feeling will bring peace to ourselves and people around us," she said. She suggested adults ought to laugh more every day, since they rarely indulged in a good chuckle. (Jakarta Post, Indonesia)

    Prevalence of type 1 diabetes linked to excessive cleanliness  Sep 22, 2008
    Scientists say the bacteria appeared to stop the rogue immune response that triggers the disease. "Potentially, if the study turns out to be confirmed, it's possible that manipulating the kind of bacteria in the gut of humans might also protect them from diabetes," Professor Tom Kay, from the St Vincent's Institute for Medical Research in Melbourne, said. (ABC Online)

    Bill Gates' millions to battle TB  Sep 22, 2008
    ----------------- ----------------- RELATED BBC SITES. Last Updated: Thursday, 12 February, 2004, 22:34 GMT. (Yahoo News -- Tuberculosis)

    New Pegloticase and Treatment Failure Gout Data to be Featured in Six Abstracts At American College of Rheumatology 72nd Annual Scientific Meeting  Sep 22, 2008
    Also to be presented in concurrent oral sessions on Tuesday, October 28 by Michael Becker, MD, will be an analysis of GOUT1 and GOUT 2 results which describe the immune response to pegloticase treatment, and the association of immunoreactivity and treatment effect. Pegloticase treated patients with the highest anti-pegloticase antibody titers failed to maintain normalization of plasma uric acid. (Primezone Releases)

    THE STUDY: Is Mate Choice in Humans MHC-Dependent?  Sep 22, 2008
    There has been a longstanding hypothesis that selection may have led to mating patterns that encourage heterozygosity at Major Histocompatibility Complex (MHC) loci because of improved immune response to pathogens in the offspring of such matings, and, indeed, this has been observed in several model systems. However, in humans, previous studies regarding the role of the MHC in mate choice or preference, both directly in couples and also indirectly in sweaty T-shirts experiments, have... (USA Today -- Tech)

    Stressed plants produce Aspirin  Sep 20, 2008
    The chemical may be a sort of immune response that helps protect the plants, the scientists said. Acetylsalicylic acid, or aspirin, was originally derived from tree bark, so scientists knew it was a compound made by plants. (India Times, India)

    Palm reading  Sep 20, 2008
    It is caused by chemicals secreted by the tumour or an immune response to the tumour. Rare. (BBC News -- Health)

    Study Helps Stop Drugs Slipping Through Safety Net  Sep 20, 2008
    Side effects can be caused by many factors relating to drug transport, immune response, and sometimes unexpected metabolic pathways, but as Pirmohamed noted, they fall into two main categories, type A and type B. "The majority (80-90%) of adverse drug reactions are type A they are predictable from the known pharmacology of the drug, are dose-dependent, and can be alleviated by reducing or identifying the correct dose for the patient," said Pirmohamed, who gave the example of the anti-coagulant... (Science Daily)

    Plants make their own painkillers  Sep 19, 2008
    Scientists think that the methyl salicylate has two functions: stimulating a process similar to the immune response in animals that helps plants resist and recover from disease, and acting as a form of chemical neighbors of threats. "These findings show tangible proof that plant-to-plant communication occurs on the ecosystem level," said study team member Alex Guenther. (MSNBC -- Politics)

    From Xbox To T-cells: Borrowing Video Game Technology To Model Human Biology  Sep 19, 2008
    In particular, the team aims to model complex biological systems, such as the human immune response to a tuberculosis bacterium ... Within a few minutes, the GPU-driven software developed by the Michigan Tech team provides a 3-D model of the human immune response to a TB infection. (Science Daily)

    Blood simple (2)  Sep 19, 2008
    Naturopathic physician Dr. Michael Bergkamp is a firm believer in food compatibility and immune response. "There are definitely foods that cause people allergies - lactose intolerance, celiac disease - if we have those, why wouldn't there be others," Bergkamp said. (Helena Independent Record)

    Cuba approves first therapeutic vaccine for lung cancer  Sep 19, 2008
    The vaccine triggers an immune response which, in addition to extending life, can ease symptoms such as difficulty breathing and lack of appetite. The idea was to "maintain or consolidate" the effects of chemotherapy and radiotherapy. (Yahoo News -- Cuba)

    Group Works to Streamline Cancer Therapy Approvals  Sep 19, 2008
    The six pathways address anti-cancer agents (drugs or biologics), biospecimen-based assessment methods, immune response modifiers, image-based assessment modalities, intervention devices, and lifestyle alterations. Each follows a flowchart. (Health-Finder)

    30-year mortgage rate at seven-month low  Sep 19, 2008
    Before working at Artes, Green was an executive at Orchestra Therapeutics, previously known as Immune Response Corp.. Sapphire Energy, a San Diego-based company making green crude oil from algae, said it has closed a $100 million Series B round of funding, giving it the financing to scale up production facilities. (San Diego Union-Tribune -- Business)

    Study identifies immune response that enables TB bacteria to ...  Sep 18, 2008
    Study identifies immune response that enables TB bacteria to multiply, provides new target for TB drugs ... Study identifies immune response that enables TB bacteria to multiply, provides new target for TB drugs ... Study identifies immune response that enables TB bacteria to multiply, provides new target for TB drugs. (News-Medical.net)

    Bovine Mastitis: Could A Vaccine Be On The Way?  Sep 18, 2008
    The team also want to identify any parts of the immune response in the dairy cow which can be altered to prevent the disease this information could subsequently be used to develop drugs that interfere with the chemical messages that lead to inflammation and therefore reduce the level of disease. In the last few months members of the Nottingham Vet School have been involved in successfully winning a number of grants and awards to support the School s growing portfolio of research. (Science Daily)

    Drug makers ignoring key gender differences, immunologist warns  Sep 18, 2008
    But the profile of that immune response is different in men and women, Dr. Fish says ... Women had a lower mortality rate from SARS than men, Dr. Fish says, possibility because their immune responses were more robust. (Globe and Mail)

    NCAR STUDY: Plants in Forest Emit Aspirin Chemical to Deal with Stress; Discovery May Help Agriculture  Sep 18, 2008
    One of these is to stimulate plants to begin a process known as systemic acquired resistance, which is analogous to an immune response in an animal ... Now that the NCAR team has demonstrated that methyl salicylate can build up in the atmosphere above a stressed forest, scientists are speculating that plants may use the chemical to activate an ecosystem-wide immune response. (USA Today -- News)

    Stressed plants produce aspirin-like chemical  Sep 18, 2008
    The chemical may be a sort of immune response that helps protect the plants, the scientists speculated. According to the researchers, the finding raises the possibility that farmers, forest managers and others may eventually be able to start monitoring plants for early signs of a disease, an insect infestation or other types of stress. (USA Today -- Tech)

    Can Stem Cells Block Stroke Damage? Yes, but in a Surprising Way  Sep 17, 2008
    Instead, the immature cells trigger adult brain cells to switch gears and block a stroke-induced immune response that causes nerve damage ... "The human cells turned down some of those inflammatory and immune responses.". (Scientific American)

    Fly studies reveal immune cell responses to tumor and tissue damage  Sep 17, 2008
    Study of tumor growth and tissue disruption identifies key components in the immune response to cancers ... The idea that tumor growth triggers the same immune response as a cut or wound was once a highly controversial notion ... Furthermore, by examining the molecular signals triggered in the immune response, Xu's team discovered that the tumor's physical disruption and damage of nearby tissues at least in part triggered the hemocyte response. (EurekAlert!)

    Viral 'magic bullet' targets cancer cells with help of new compound  Sep 17, 2008
    "It is not a human pathogen, so most individuals do not have antibodies directed against it, which means there is a window of opportunity to successfully treat patients before they mount an immune response.". Dr. Hiscott and his colleagues are enthusiastic that this new approach may lead to the rapid implementation of new experimental therapies for breast, prostate, colon and other primary cancers that are currently resistant to virotherapy. (EurekAlert!)

    Colorful spy tactics track live cells supporting cancerous tumors  Sep 17, 2008
    As a tumor grows, it triggers immune responses in the body, and recruits assistance from normal cells in order to "feed" and support the spread of the cancerous growth ... This in turn aids in identifying drug targets which can be inhibited to prevent the spread of cancer, or conversely, targets which can be stimulated to enhance the body's natural immune response to cancer. (EurekAlert!)

    New Pathway For Malaria Infection Discovered  Sep 16, 2008
    (May 16, 2007) A new study suggests that bites from mosquitoes not infected with malaria may trigger an immune response limiting parasite development following bites from infected ... 9, 2006) A weakened immune response resulting from HIV infection can lead to trouble when it comes to treating malaria, according to a new study appearing in the Oct. 1 issue of the Journal of Infectious. (Science Daily)

    New tool to speed cancer therapy approval available  Sep 15, 2008
    There are six Pathways that address the following categories: anti-cancer agents (drugs or biologics), biospecimen-based assessment methods, immune response modifiers, image-based assessment modalities, intervention devices, and lifestyle alterations. Each pathway is a flowchart with a series of steps intended to clarify and streamline the translational research process. (EurekAlert!)

    Vaccine against HER2-positive breast cancer offers complete protection in lab  Sep 15, 2008
    "The immune response against HER2-positive receptors we saw in this study is powerful, and works even in tumors that are resistant to current therapies," she said. "The vaccine could potentially eliminate the need to even use these therapies.". (EurekAlert!)

    Lettuce May Help Millions Diagnosed With Diabetes  Sep 15, 2008
    This stimulates an immune response and tells the body to produce its own insulin ... This creates an immune response in the body and teaches it to release its own insulin. (KLAS-TV)

    Untapped Potential Of Antidepressants For Cancer  Sep 14, 2008
    13, 2008) A comprehensive review of current scientific literature, published in the peer-reviewed journal ecancer, has suggested that antidepressants can help the human body fight cancer by boosting its own immune response, amongst other mechanisms. See also. (Science Daily)

    Mate selection more biologically determined in some human populations  Sep 12, 2008
    In several species it has been shown that the Major Histocompatibility Complex (MHC), a large genomic region involved in immune response, influences mating selections and that this may be mediated by preferences based on body odor. Some previous studies have reported a tendency for humans to prefer MHC-dissimilar mates, encouraging heterozygosity at MHC loci in offspring and resulting in improved immune response. (EurekAlert!)

    Bacteria's Sticky Glue Is Clue To Vaccine, Says Scientist  Sep 11, 2008
    "To grow as a biofilm the bacteria must produce sticky factors, one of which is a type of complex sugar called PNAG. We are targeting this material as a possible vaccine, but natural exposure to the sugar compound does not result in most people and animals making an immune response that would protect them from attack by the bacteria or recurring infections," said Professor Pier. By manipulating the sugar chemically the scientists have discovered that they can produce variant forms which can be... (Science Daily)

    Potential Approach To Treatment Of Hepatitis B Virus Infection  Sep 11, 2008
    (July 18, 2007) As it is not quite clear how HIV patients that don't respond to the HBV vaccine should be managed, new research has evaluated the immune response of HBV vaccine given intradermally (into the skin) in. (Apr. (Science Daily)

    Individuals vary their immune response according to age, sex and the costs  Sep 11, 2008
    Is it always good to respond maximally when pathogens or disease strike, or should individuals vary their immune response to balance immediate and future costs. This is the question evolutionary physiologists Oliver Love, Katrina Salvante, James Dale, and Tony Williams asked when they examined how a simple immune response varied at different life stages across the life-span of individual zebra finches (Taeniopygia guttata), in a study published in the September issue of the American Naturalist... (EurekAlert!)

    Bacteria glue helps fight superbugs  Sep 11, 2008
    LONDON: A sticky glue secreted by drug-resistant bacteria could help scientists develop an effective vaccine against superbugs", US researchers told a conference on Wednesday. The sticky substance is a complex sugar called PNAG which the researchers said was a promising vaccine target because animal studies have shown it produces a protective immune response when manipulated chemically. The bacteria produces the substance when growing a biofilm that protects them from antibiotics, Gerald Pier... (India Times, India -- Health/Science)

    $11.5 Million for UR Cancer Research  Sep 10, 2008
    The research will center on four areas: discovering how lymphoma cells function, strengthening the body's natural immune response, improving existing drugs, and examining the role of stem cells. Right now, 40 percent of lymphoma patients treated in Rochester come from outside the area. (WOKR13 Rochester)

    Catching The Blood Cell Bus Gives Fatal Yeast Infection A Clean Getaway  Sep 10, 2008
    The death of the host cell releases debris and by-products which usually triggers our bodies into mounting an immune response, causing inflammation. "This new method of remaining inside the host cells means that the pathogen can spread more efficiently round our bodies and is protected from the natural defences in our bloodstream that would normally kill the yeast or other invader," said Hansong Ma. (Science Daily)

    Universal flu vaccine the 'Holy Grail' of flu shots  Sep 9, 2008
    Dr. Sarah Gilbert, the study leader, from the Jenner Institute at Oxford, says traditional influenza vaccines are designed to prompt an immune response to H and N proteins on the outer shell of the virus but the new vaccine could provide universal vaccination where everyone is protected. Dr. Gilbert these proteins are notoriously prone to mutation and every year the vaccine has to be reformulated on the basis of the strains likely to be most prominent. (News-Medical.net)

    Best Way To Treat Malaria: Avoid Using Same Drug For Everyone, Scientists Say  Sep 9, 2008
    9, 2006) A weakened immune response resulting from HIV infection can lead to trouble when it comes to treating malaria, according to a new study appearing in the Oct. 1 issue of the Journal of Infectious. . (Science Daily)

    Scientists Identify Genetic Link That May Neutralize HIV  Sep 8, 2008
    "We now have a host factor needed for the production of neutralizing antibodies that HIV targets and destroys," said Gladstone scientist Mario Santiago, PhD. "This offers a fresh perspective on how to strengthen this arm of the immune response against HIV, with direct implications for immunotherapy and vaccine development." ... (July 14, 2008) Recent studies have shown that HIV causes a vigorous and prolonged immune response that eventually leads to the exhaustion of key immune system cells --... (Science Daily)

    Universal flu vaccine tests start  Sep 6, 2008
    Study leader, Dr Sarah Gilbert, said traditional influenza vaccines are designed to prompt an immune response to H and N proteins on the outer shell of the virus. With this vaccine, we could end up having pretty much everyone vaccinated - a situation more like measles where you don't really see it anymore. (BBC News)

    African health ministers to introduce meningitis vaccines  Sep 6, 2008
    "Priced at just US$ 0.40 per dose, the vaccine produces in both adults and toddlers a higher immune response than the currently available vaccine. In addition, the new vaccine confers long-term protection and induces immunity in certain non-vaccinated persons who live in proximity of those who are immunized, leading to broad community protection," the statement said. The new product, conjugate meningococcal A vaccine ("MenAfriVac"), was developed through the Meningitis Vaccine Project a product... (Ghana Web, Ghana)

    African ministers agree to roll out vaccine to fight meningitis  Sep 5, 2008
    The new vaccine, priced at just 40 cents a dose, produces a higher immune response in both toddlers and adults than the current vaccine, according to the World Health Organization (WHO),which is running the week-long conference. The WHO reported in a press release that the vaccine not only offers long-term protection but also defends non-vaccinated people, living in close proximity to their immunized neighbors, against the disease. (Xinhua)

    * Ho team makes H5N1 vaccines  Sep 5, 2008
    Based on the experiments and research conducted by other scientists, DNA-based vaccines tend to elicit a weak immune response, said Chen Ming-wei, a post-graduate student at National Yang-Ming University and the lead author of the paper ... Delivered in this fashion, DNA-based vaccines induce quite drastic immune responses and protect mice against most of the avian flu strains tested, he said. (Taipei Times, Taiwan -- World)

    Adherence to antiretroviral therapy in young children in Cape Town, South Africa, measured by medication return and caregiver self-report: a prospective cohort study.  Sep 5, 2008
    Viral and immune response to treatment were assessed at the end of one year and associations with measured adherence determined. Results. (BioMed Central)

    BioMS Medical's lead drug, dirucotide (MBP8298) for the treatment of multiple sclerosis, receives fast track designation from FDA  Sep 4, 2008
    The primary clinical endpoint for the trial is defined as a statistically and clinically significant increase in the time to progression of the disease as measured by the Expanded Disability Status Scale (EDSS), in patients with HLA-DR2 and/or HLA-DR4 immune response genes (up to 75% of all MS patients are HLA-DR2 and/or HLA-DR4 positive) ... The sequence of dirucotide is associated with the autoimmune process in MS patients with certain immune response genes (HLA types DR2 and/or DR4); MS... (Canada Newswire)

    Early Onset Gene For Inflammatory Bowel Diseases Identified  Sep 4, 2008
    TNFRSF6B encodes a protein that lengthens the duration of an immune response by regulating the longevity of activated white blood cells. Kugathasan notes that a related protein, tumor necrosis factor alpha, is the target of an existing antibody treatment for inflammatory bowel disease. (Science Daily)

    Double Hepatitis Vaccine Boosts Immune Response  Sep 4, 2008
    NEW YORK (Reuters Health) - About 5 percent to 10 percent of adults don't have an adequate immune response when they're vaccinated against the hepatitis B virus, which means they're still at risk of catching the infection ... Their study involved 48 healthcare workers who had failed to have a good immune response to hepatitis B vaccination. (MEDLINEplus)

    Hemispherx Biopharma to Present At BioPharm America Conference  Sep 3, 2008
    The TLRs are essential in the induction of innate immunity and are required for a vigorous adaptive immune response to antigens, and may now loom critically important in view of numerous cancer/HIV/AIDS vaccine trials which have just recently failed due to the absence of adequate stimulation of innate immune responses ... Ampligen(r) has been demonstrated recently to provide significant immune response to H5N1 highly pathogenic influenza virus (HPIV) in primate studies conducted at the Japanese... (Primezone Releases)

    Previous claims of siRNA therapeutic effects called into question by report in human gene therapy  Sep 3, 2008
    New Rochelle, NY, September 2, 2008The many recent reports documenting the therapeutic efficacy of short interfering RNAs (siRNAs) in animal models of human disease may actually be describing non-specific therapeutic effects related to the ability of siRNA to activate an immune response, according to a paper in the September 2008 issue (Volume 19, Number 9) of Human Gene Therapy, a peer-reviewed journal published by Mary Ann Liebert, Inc. The paper, which was published "instant online," is... (EurekAlert!)

    Cellular profile of the peritumoral inflammatory infiltrate in squamous cells carcinoma of oral mucosa :correlation with the expression of Ki67 and histologic grading.  Sep 3, 2008
    The local immune response represented by peritumoral inflammatory infiltrate is a possible prognostic factor ... Conclusions: The results suggest that the cellular immune response is the main defense mechanism in squamous cells carcinoma of oral mucosa, expressed by the large number of T lymphocytes and macrophages, and that the greatest intensity of local response may be associated with the best prognosis. (BioMed Central)

    New Test Identifies Heart Transplant Rejection  Aug 29, 2008
    A successful transplant is achieved when the body's immune response is suppressed enough to accept the new organ but is strong enough to continue warding off infection, the agency said. Half of all rejections occur in the first six weeks after transplant, and about one-quarter of recipients have evidence of rejection within the first year, according to government data cited by the agency. (U.S. News & World Report)

    NIAID Describes Challenges, Prospects For An HIV Vaccine  Aug 29, 2008
    Also, studying the earliest stages of HIV infection may shed light on ways to manipulate innate and mucosal immune responses to widen the window of opportunity for viral eradication, to prevent the virus from advancing to gut-associated lymphoid tissue, or both ... (July 18, 2007) As it is not quite clear how HIV patients that don't respond to the HBV vaccine should be managed, new research has evaluated the immune response of HBV vaccine given intradermally (into the skin) in ... (July 14,... (Science Daily)

    Genetic Underpinnings Of Sheep Traits May Yield Clues To Greater Productivity  Aug 29, 2008
    At Pullman, ARS scientists Lynn Herrmann-Hoesing, Stephen White and Donald Knowles, who leads ADRU, are using the tissue samples to study whether ovine progressive pneumonia virus levels are affected by specific sheep immune response genes. Their goal is a molecular test with which to measure the levels of such infectious agents in sheep. (Science Daily)

    Bill Gates' millions to battle TB  Aug 29, 2008
    ----------------- ----------------- RELATED BBC SITES. Last Updated: Thursday, 12 February, 2004, 22:34 GMT. (Yahoo News -- Tuberculosis)

    Genes and Immunity  Aug 29, 2008
    Volume 9, No 5July 2008ISSN: 1466-4879EISSN: 1476-5470. 2007 impact factor 4. (Nature News Service)

    Chronic Stress Alters Our Genetic Immune Response  Aug 28, 2008
    They found that among the caregivers, even though they had normal cortisol levels in their blood, the pattern of gene expression in the monocytes, a type of white blood cell involved in the body's immune response, was altered so that they were relatively less responsive to the anti-inflammatory actions of cortisol, but relatively more responsive to pro-inflammatory actions of a transcription factor called nuclear factor-kappa B, or NF- B.. Gregory Miller, Ph. (Science Daily)

    Canine Pemphigus  Aug 27, 2008
    Pemphigus is caused by an abnormal immune response that causes skin cells to separate. Rarely, cats are also affected. (Suite101.com)

    Novavax Moves Closer to Licensing Bird Flu Vaccine  Aug 27, 2008
    said yesterday that its bird flu vaccine elicited a robust immune response in humans, moving the biotech a step closer to licensing its pandemic vaccine production system ... Novavax's bird flu vaccine uses particles that mimic the size and shape of the virus, which trigger an immune response but lack the genetic material to replicate ... After tweaking the production process, the biotech was able to elicit a stronger immune response in this recent trial. (Washington Post)

    Cuba approves first therapeutic vaccine for lung cancer  Aug 27, 2008
    The vaccine triggers an immune response which, in addition to extending life, can ease symptoms such as difficulty breathing and lack of appetite. The idea was to "maintain or consolidate" the effects of chemotherapy and radiotherapy. (Yahoo News -- Cuba)

    Novavax says experimental bird flu vaccine works  Aug 27, 2008
    Inc. says its experimental vaccine against one strain of avian influenza produced a strong immune response in humans. The Rockville-based company, using technology that can cut the time it takes to manufacture vaccines in half, says the vaccine showed strong antibody activity at three levels of dosing among 160 patients taking part in the clinical trial, with the best response in patients getting the highest dose. (Washington Business Journal, DC)

    Early trigger for type-1 diabetes found in mice, Stanford scientists report  Aug 27, 2008
    However, in mice that develop diabetes, debris left behind by the dying cells triggers an inappropriate immune response, with lots of interferon-alpha. The interferon-alpha cues immune destruction of more and more beta cells, causing insulin deficiency and diabetes. (EurekAlert!)

    ZOSTAVAX(TM) approved in Canada - The first and only vaccine for the prevention of shingles  Aug 26, 2008
    The vaccine uses essentially the same ingredients as VARIVAX(R), Merck Frosst's chickenpox vaccine, but has higher potency in order to induce a significant immune response to varicella-zoster virus in older adults(8). In the Shingles Prevention Study (SPS) of 38,546 subjects 60 years of age or older, the new shingles vaccine reduced the risk of developing herpes zoster compared with placebo by 64 per cent in people aged 60 to 69(9) and by 51 per cent for all age groups(10). (Canada Newswire)

    New study shows health benefits of probiotic could extend to the entire body  Aug 25, 2008
    The normal response to infection is rapid and effective, however, the immune response may occasionally cause inflammation and damage to healthy tissue. "Inflammation is a major factor in a number of chronic diseases affecting millions of people and can cause an unwanted impact on healthy tissue," said Dr. Liam O'Mahony, lead investigator. (EurekAlert!)

    Native human autoantibodies targeting GIPC1 identify differential expression in malignant tumors of the breast and ovary  Aug 25, 2008
    We have been studying the native humoral immune response to cancer and have isolated a library of fully human autoantibodies to a variety of malignancies. We previously described the isolation and characterization of two fully human monoclonal antibodies, 27. (BioMed Central)

    A new weapon to fight cancer - tobacco?  Aug 22, 2008
    The made-to-order vaccine has been tested in an early-stage clinical trial, and it showed an immune response in 70 percent of non-Hodgkin's lymphoma patients without harmful side effects. Even though it is called a vaccine, it will not prevent a person from getting non-Hodgkin's lymphoma, which is the seventh-leading cause of cancer-related deaths in the United States. (AZCentral -- Business)

    Cancer-Free Girls  Aug 22, 2008
    The immune response to the vaccine is exceptionally strong when administered to girls this young ... It's precisely because their daughters are not yet sexually active, and also have such powerful immune responses, that this is the ideal age. (Slate)

    Drug Makers' Push Leads to Cancer Vaccines' Fast Rise  Aug 20, 2008
    A Glaxo spokeswoman, Sarah Alspach, said its formulation produces a stronger and longer-lasting immune response than conventional vaccines. You can only study a vaccine for so long before you license and use it in a population where it has enormous value, said Dr. Haupt at Merck. (Atlanta Journal-Constitution -- Health)

    Affitech and Omeros Enter Into Antibody Discovery and Development Agreement  Aug 19, 2008
    Importantly, inhibition of MASP-2 does not appear to interfere with the antibody-dependent classical complement activation pathway, a critical component of the acquired immune response to infection, and its abnormal function is associated with a wide range of autoimmune disorders. Omeros holds worldwide exclusive licenses to rights related to MASP-2, the antibodies targeting MASP-2 and the therapeutic applications for those antibodies from the University of Leicester and from its collaborator,... (PR Newswire)

    Immune Response May Hinder Stem Cell Treatments  Aug 19, 2008
    MONDAY, Aug. 18 (HealthDay News) -- Human embryonic stem cells trigger an immune response in mice, a new study finds ... Researchers at Stanford University School of Medicine found that common anti-rejection medications could counter the mice's immune response ... "In fact, the rejection of these cells confirms our suspicions that they do cause an immune response.". (U.S. News & World Report)

    Leishmaniasis Parasites Evade Death By Exploiting Immune Response To Sand Fly Bites  Aug 19, 2008
    18, 2008) Cutaneous leishmaniasis, a disease characterized by painful skin ulcers, occurs when the parasite Leishmania major, or a related species, is transmitted to a mammalian host by the bite of an infected sand fly. In a new study from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, scientists have discovered L. major does its damage by not only evading but also by exploiting the body's wound-healing response to sand fly bites, as... (Science Daily)

    Stanford scientists suggest stem-cell monkey-wrench  Aug 19, 2008
    Researchers at Stanford s medical school found that human embryonic stem cells widely touted as the next medical panacea triggered an immune response in mice, which could limit the effectiveness of treatments derived from them ... Antirejection medications, commonly used in organ transplantation, can suppress the immune response, the researchers found ... Based on these results, we believe that transplanting these cells into humans would also cause an immune response. (San Francisco Business Times, CA)

    ImmuneRegen BioSciences, ASU work to sink cruise ship diarrhea  Aug 19, 2008
    The study will look at the effectiveness of ImmuneRegen's Viprovex to boost the immune response in conjunction with plant-derived vaccines against noroviruses, also called Norwalk-like viruses ... He and his team have engineered tobacco plants to produce high levels of Norwalk-virus capsid protein, an antigen used to elicit an immune response during vaccination ... Viprovex will be administered in conjunction with this antigen to assess whether the drug further enhances the immune response in... (Phoenix Business Journal, AZ)

    Flu not only killer in 1918 pandemic  Aug 19, 2008
    But to explain the 1918 pandemic's unusual virulence, many scientists had come to believe that the virus caused death by provoking an overzealous, destroy-the-village-to-save-it immune response, especially in young adults with robust immune systems ... Michael Katze, a University of Washington virologist who was a lead scientist in the mice and monkey experiments, said the animals' violent and rapid immune response made it almost unreasonable to expect victims of the 1918 virus to live long... (San Francisco Chronicle)

    Stanford stem-cell study: human therapy may be limited  Aug 19, 2008
    Human embryonic stem cells trigger an immune response in mice, researchers from the reported Monday, suggesting that the effectiveness of human therapies derived from the cells could be limited unless ways are found to dampen the rejection response. The researchers found the immune response in mice could be mitigated by the use of common antirejection medications ... In fact, the rejection of these cells confirms our suspicions that they do cause an immune response. (East Bay Business Times, CA)

    'NATURE' ARTICLE:  Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors  Aug 19, 2008
    It is well established that a subset of plasma cells is long-lived, and these cells contribute to durable humoral immune responses, such as that observed after childhood smallpox vaccination ... Kobasa, D. et al. Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus. (USA Today -- Tech)

    Survivors of 1918 Flu Pandemic Immune 90 Years Later  Aug 18, 2008
    He believes more work needs to be done understand the full extent of this immune response ... "This study shows that humans can develop very potent immune responses against dangerous influenza that cause pandemics," Crowe said ... Dr. Marc Siegel, an associate professor of medicine at New York University School of Medicine in New York City, thinks that people who developed this strong immune response may have been infected with a less deadly strain of flu before 1918. (Washington Post)

    1918 flu antibodies resurrected from elderly survivors  Aug 18, 2008
    With fears of another looming flu pandemic stoked by the emergence of "bird flu" in Asia, researchers have wanted to study the 1918 virus and the immune response to it. In 2005, researchers from Mount Sinai and the Armed Forces Institute of Pathology in Washington, D.C., resurrected the 1918 virus from the bodies of people killed in the outbreak. (EurekAlert!)

    Contraceptive Pills Can Make You Pick The Wrong Lover  Aug 17, 2008
    Major histocompatibility complex (MHC) genes are involved in immune response and other functions. According to various studies, female generally choose male with dissimilar MHC smell. (TopNews)

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