'IT'S VERY SERIOUS': Cordova woman diagnosed with TTP wants to raise awareness about the rare blood disorder Jun 3, 2008
I have an aunt who had ITP (immune thrombocytopenic purpura), the lesser version of TTP," said Cleckley, who has been taken off prednisone and chemotherapy. "My dad had a blood disorder. He passed away in August of 2007. (Orangeburg Times and Democrat, SC)
Immunomedics Reports High Anti-Lymphoma Potency With Veltuzumab Jun 2, 2008
We plan to submit preliminary results from this study, as well as the study in patients with immune thrombocytopenic purpura (ITP), to this year's annual meeting of the American Society of Hematology for presentation,'' commented Cynthia L. Sullivan, President and CEO. ``We are progressing towards our near term goal of completing the out-licensing of veltuzumab,'' she further remarked ... In addition, the Company is conducting clinical trials with intravenous veltuzumab in patients with NHL and... (Primezone Releases)
Immunomedics' Pretargeting Method May Improve Radioimmunotherapy of Cancer Apr 14, 2008
In addition, the Company is conducting clinical trials with intravenous veltuzumab in patients with NHL and immune thrombocytopenic purpura, subcutaneous veltuzumab in NHL and chromic lymphocytic leukemia (CLL), 90Y-epratuzumab for the therapy of patients with lymphoma, 90Y-hPAM4 combined with gemcitabine for pancreatic cancer therapy, and milatuzumab (anti-CD74 humanized antibody) as a therapy for patients with multiple myeloma, NHL, and CLL. We also have a majority ownership in IBC... (Primezone Releases)
Immunomedics' Product Candidates Being Presented At 2008 American Association for Cancer Research Annual Meeting Apr 10, 2008
In addition, the Company is conducting clinical trials with intravenous veltuzumab in patients with NHL and immune thrombocytopenic purpura, subcutaneous veltuzumab in NHL and chromic lymphocytic leukemia (CLL), (90)Y-epratuzumab for the therapy of patients with lymphoma, (90)Y-hPAM4 combined with gemcitabine for pancreatic cancer therapy, and milatuzumab (anti-CD74 humanized antibody) as a therapy for patients with multiple myeloma, NHL, and CLL. We also have a majority ownership in IBC... (Primezone Releases)
The Panelling on Amgen's Walls Mar 18, 2008
Amgen's first positive outcome in recent memory from an FDA advisory panel hearing came Tuesday, after a panel voted unanimously to recommend approval of its immune thrombocytopenic purpura (ITP) treatment, Romiplostim. ITP is the cause of those purple bruises on some elderly people's arms and is a result of low blood platelet count. (MSNBC -- Business)
Immunomedics' Milatuzumab Receives FDA Orphan Drug Designation for Therapy of Multiple Myeloma Mar 18, 2008
The Company is conducting clinical trials with veltuzumab in patients with non-Hodgkin's lymphoma and immune thrombocytopenic purpura, epratuzumab as a potential therapeutic for patients with lymphoma and leukemia, 90Y-epratuzumab for the therapy of patients with lymphoma, 90Y-hPAM4 for pancreas cancer therapy and milatuzumab as a therapy for patients with multiple myeloma, non-Hodgkin's lymphoma, and chronic lymphocytic leukemia. We believe that our portfolio of intellectual property, which... (Primezone Releases)
Effective Treatment Found For Hepatitis C Patients With Low Blood-platelet Counts, Study Suggests Jan 6, 2008
With other eltrombopag findings, NewYork-Presbyterian/Weill Cornell's Dr. James Bussel led research, also reported in the New England Journal of Medicine, finding the platelet growth factor successfully increased platelet counts and decreased bleeding in patients with Immune Thrombocytopenic Purpura (ITP), an autoimmune disease that dramatically reduces the number of platelets in their blood ... 29, 2007) There are estimated to be between 50,000-100,000 individuals in the US diagnosed with... (Science Daily)
Hospital failed to detect babys death, says teacher Dec 14, 2007
Khairul said his wife suffered from Immune thrombocytopenic purpura that causes low blood palette count, and she was hospitalised several times during the last two months. He said he was giving the hospital a week to explain, failing which he would take legal action. (The Star Online, Malaysia -- News)
UPDATE 1-Amgen study shows platelets response with Nplate Dec 12, 2007
LOS ANGELES, Dec 10 (Reuters) - Amgen Inc AMGN.O said on Monday its experimental drug AMG 531 had the desired effect of increasing platelet production in adults with a bleeding disorder known as chronic immune thrombocytopenic purpura. The Phase 3 trial of the drug, also known as Nplate or romiplostim, studied 62 ITP patients who had failed previous treatments. (Reuters)
Cephalon, Celgene Kick Off ASH Confab Dec 11, 2007
12/8/2007 9:18 PM ESTIn a phase III trial, the treatment increased platelets in patients with Immune Thrombocytopenic Purpura. Biotech. (TheStreet.com)
Research Highlights New Approaches to Management of Blood Clotting and Bleeding Disorders Dec 9, 2007
ATLANTA, Dec. 8 /PRNewswire-USNewswire/ -- Data that shed new light on the treatment of residual vein thrombosis, thromboprophylaxis after total hip replacement, chronic immune thrombocytopenic purpura, and venous thrombosis in relation to postmenopausal hormone replacement therapy will be presented at the 49th Annual Meeting of the American Society of Hematology in Atlanta, GA. A press conference will reveal this new research on Saturday, December 8, from 10:00 to 11:00 a.m. "Complications... (PR Newswire)
Pivotal Phase 3 Romiplostim Study in Splenectomized Patients Meets Primary Endpoints Dec 9, 2007
Data Show Romiplostim Increased and Sustained Platelet Counts in Splenectomized Adult Patients with Immune Thrombocytopenic Purpura. ATLANTA--()--Amgen Inc. (NASDAQ:AMGN) today announced results from a randomized, pivotal Phase 3 study that showed romiplostim (AMG 531) increased and sustained platelet counts in splenectomized (spleen removed) adult patients with chronic Immune Thrombocytopenic Purpura (ITP). (BusinessWire)
Amgen study shows romiplostim boosts platelets Dec 9, 2007
LOS ANGELES (Reuters) - Amgen Inc said on Saturday that a late-stage trial of its experimental drug AMG 531 showed it boosted and sustained platelet counts in adults with chronic immune thrombocytopenic purpura, a bleeding disorder. The Phase 3 Amgen-sponsored trial included 63 chronic ITP patients, who had their spleens removed after other treatments had failed. (ABC News -- Wire)
Pill Boosts Platelets In Hepatitis C Patients Nov 30, 2007
29, 2007) There are estimated to be between 50,000-100,000 individuals in the US diagnosed with chronic Immune Thrombocytopenic Purpura, an autoimmune disease that dramatically reduces the number of platelets. (Sep. (Science Daily)
Immune Thrombocytopenic Purpura — From Agony to Agonist Nov 29, 2007
NEJM -- Immune Thrombocytopenic Purpura -- From Agony to Agonist ... Immune Thrombocytopenic Purpura From Agony to Agonist. (New England Journal of Medicine)
Eltrombopag studied in Idiopathic Thrombocytopenic Purpura Nov 29, 2007
29, 2007) -- There are estimated to be between 50,000 -- 100,000 individuals in the U.S. diagnosed with chronic Immune Thrombocytopenic Purpura (ITP), an autoimmune disease that dramatically reduces the number of platelets in their blood -- causing bruises, nosebleeds and, sometimes, life-threatening brain hemorrhages ... Immune thrombocytopenic purpura (ITP) is an autoimmune disease in which anti-platelet antibodies accelerate destruction of platelets. (EurekAlert!)
Bearing her soul: RBV's Crabtree works to brighten lives of young cancer patients Nov 13, 2007
She was hospitalized with immune thrombocytopenic purpura, a syndrome in which one's blood has difficulty clotting because of an unusually low number of platelets. Crabtree said she contracted scarlet fever, strep throat and chicken pox at the same time. (North County Times)
Genzyme gets OK to resume testing of MS drug May 17, 2007
He said the clinical trial so far has yielded five other cases of the bleeding disorder, called immune thrombocytopenic purpura , or ITP. All of those patients were treated and recovered. With early detection and treatment, the problem amounts to a "manageable risk" for Campath patients, said the company. (Boston Globe)
AMG 531 for Chronic ITP Jan 18, 2007
19 issue)1 justify the rationale for using the thrombopoiesis-stimulating drug AMG 531 in chronic immune thrombocytopenic purpura (ITP) by citing previous reports on abnormalities of megakaryocytic survival and maturation in this disorder. However, studies of defective platelet production in ITP have yielded conflicting results,2,3 and the present study provides no evidence of such an abnormality in any patient. (New England Journal of Medicine)
Rigel starts mid-stage trial of blood disorder treatment Jan 9, 2007
The South San Francisco company (NASDAQ: RIGL) is testing the product, R788, for treatment of patients with refractory immune thrombocytopenic purpura. It is a blood disorder in which the immune system attacks platelets. (San Francisco Business Journal)
Immune Thrombocytopenic Purpura — The Changing Therapeutic Landscape Oct 19, 2006
NEJM -- Immune Thrombocytopenic Purpura -- The Changing Therapeutic Landscape ... Immune Thrombocytopenic Purpura The Changing Therapeutic Landscape ... Immune thrombocytopenic purpura (ITP) in adults is usually a chronic disease in which a low platelet count often causes mucocutaneous bleeding. (New England Journal of Medicine)
AMG 531 in Immune Thrombocytopenia Oct 19, 2006
Background Most current treatments for chronic immune thrombocytopenic purpura (ITP) act by decreasing platelet destruction. In a phase 1 2 study, we administered a thrombopoiesis-stimulating protein, AMG 531, to patients with ITP.. (New England Journal of Medicine)
Fairfield County Scene Sep 24, 2006
Darien Sport Shop ITPMAN Triathlon The ITP Foundation, dedicated to battling the rare bleeding disorder of immune thrombocytopenic purpura, holds a triathlon to raise awareness and funds. Saturday. (Stamford Advocate)
Jonathan Davis' Near-Death Experience Has Him Talking God, Politics Jul 13, 2006
who was diagnosed with immune thrombocytopenic purpura last month and was forced to cancel the band's remaining European tour dates (see ). "Thank God that someone's looking out for me from up there and I'm still here," Davis said. (VHI.com -- Music News)
Korn's Davis Itching To Get Back On Stage... Jun 21, 2006
Davis was rushed to a London hospital earlier this month after developing the blood disorder immune thrombocytopenic purpura (ITP), forcing Korn to scrap the rest of its European tour. "We had just done a show in Hamburg, Germany," Davis recalls. (Billboard.com)
Billboard Bits: Korn, Thrice, John McLaughlin, Topley-Bird... Jun 14, 2006
Korn frontman Jonathan Davis has been released from a London hospital, where he has been treated over the past four days for the blood ailment immune thrombocytopenic purpura. (June 12), Korn was forced to scrap its remaining European tour dates while David recovers. (Billboard.com)
Korn Kancels Euro Tour Jun 13, 2006
Doctors told him he had immune thrombocytopenic purpura, an infection that prevents platelets produced by bone marrow from clotting normally. "I started getting these weird bruises all over my body about two weeks ago. I was getting very weak after the shows so I saw a doctor in London Friday," writes Davis. (E! Online)
Davis Taken Ill, Korn Cancels European Tour Jun 13, 2006
Davis is suffering from the blood disorder immune thrombocytopenic purpura and has been ordered by doctors not to perform for several weeks, necessitating scrapping dates through July 2 in Leipzig, Germany. The band is hoping to reschedule the shows later this year. (Billboard.com)
Korn cancels European tour Jun 13, 2006
Davis was admitted to a London hospital Friday with a blood disorder called immune thrombocytopenic purpura, which is described as a clotting disorder, MTV.com reported. A spokesperson for the band said Davis is expected to be down for at least three weeks. (Washington Times, DC)
Korn's Jonathan Davis Hospitalized With Blood Ailment; Tour Canceled Jun 13, 2006
Korn frontman Jonathan Davis was admitted to a London hospital over the weekend for treatment of a blood disorder called immune thrombocytopenic purpura, forcing the band to pull out of at least one European festival gig and deliver an abbreviated. set with guest singers at Saturday's U.K. Download Festival. (VHI.com -- Music News)
Baxter warns of hazard to patients using WinRho Jan 7, 2006
Patients with immune thrombocytopenic purpura, or ITP, should immediately alert their doctors if they experience back pain, shaking or chills, fever, discolored urine or decreased urine output, sudden weight gain, fluid retention, swelling or shortness of breath, Deerfield, Ill. -based Baxter Healthcare Corp. and Cangene Corp. said. (Crain's Chicago Business)
