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    News and Articles on In vitro

    Archives: In vitro

    Top 20 medical breakthroughs for women  Dec 2, 2008
    InfertilityGood news for frozen embryosFreezing embryos allows couples to have several in vitro fertilization cycles from the same egg collection or enables them to hold off for a better time for implantation in a mother who may be undergoing chemotherapy or may have other issues that require her to delay pregnancy. And a new, landmark study from Denmark found that babies born from previously frozen embryos have no increased risk of low birth weight, birth defects, or compromised health,... (MSNBC -- Health)

    * New hope for AIDS patients in Africa  Dec 2, 2008
    The Cape Fertility Clinic is the first in Africa to open a laboratory for HIV-positive patients, enabling them to conceive and give birth to HIV-negative babies by using procedures such as in vitro fertilization. HIV is no longer seen as a death sentence but a chronic disease, said Klaus Wiswedel, one of the clinics directors. (Taipei Times, Taiwan -- World)

    Test-tube Babies Profitable Business For The State, Swedish Study Shows  Dec 2, 2008
    Subsidized in vitro fertilization is not a total solution for aging populations, but it is part of a strategy ... The author of the article points out that there are great regional differences in Sweden today when it comes to how easy it is to get access to county-subsidized in vitro fertilization ... Our calculations show that in a long-term perspective in vitro fertilization doesn t cost the state anything at all since the state actually sees a return on its investment in the form of the tax... (Science Daily)

    HIV+ and looking to conceive  Dec 2, 2008
    "We've had to turn people away," said Mary Lyne, manager of the hospital's reproductive biology unit and in vitro fertilization program ... Their findings, presented earlier this month at the annual meeting of the American Society for Reproductive Medicine, showed only 30 per cent offered sperm washing for HIV-positive men, and only 20 per cent offered in vitro fertilization for HIV-positive women. (Globe and Mail)

    Immunomedics to Present At 50th ASH Annual Meeting  Dec 2, 2008
    --"Radioimmunotherapy of Non-Hodgkin Lymphoma is Improved without Increasing Toxicity by Combination with Antibody Immunotherapy" (Publication No. 1588, Session Name: Lymphoma: Pre-Clinical - Chemotherapy and Biologic Agents Poster I, Saturday, December 6, 5:30 p.m. - 7:30 p.m., Board # I-693, Moscone Center, Hall A) --"A Novel Anti-CD20 IgG-Interferon-alpha2b Fusion Protein with Potent in Vitro and in Vivo Anti-Lymphoma Activity Made by the Dock-and-Lock (DNL) Method" (Publication No. 1590,... (Primezone Releases)

    Stem Cell Researchers Praise Obama Policy  Nov 29, 2008
    Such cells, often taken from extra embryos created by in vitro fertilization clinics, can morph into the specialized cells found in skin, nerves and many other tissues. Bush shared the moral objections of some religious groups and political conservatives to research on human embryos. (San Francisco Chronicle -- Politics)

    Hormones: The Reason Why Females With Cystic Fibrosis Have A Worse Outlook Than Males With The Disease  Nov 29, 2008
    As the estrogen antagonist tamoxifen blocked one aspect of the molecular mechanism in vitro, the authors suggest that antiestrogens might be beneficial in the treatment of cystic fibrosis. In an accompanying commentary, Pamela Zeitlin, at Johns Hopkins School of Medicine, Baltimore, outlines the complexities of the molecular mechanism uncovered by Tarran and colleagues, and further discusses the clinical implications of the data. (Science Daily)

    Tumor Environment Determines Whether The Cellular Process Autophagy Enables Cancer Cells To Live Or Die  Nov 28, 2008
    In the study, in vitro re-expression of ARHI in multiple human ovarian cancer cell lines induced autophagy and cell death. However, when one of these cells lines was transplanted into mice as a xenograft, multiple factors within the tumor environment turned ARHI-induced autophagy into a mechanism of tumor cell survival, leading to tumor dormancy. (Science Daily)

    Nitric Oxide Can Alter Brain Function  Nov 28, 2008
    "It is broadly localized in the central nervous system, where it influences synaptic transmission and contributes to learning and memory mechanisms. However, because it is normally released in such minute quantities and is so labile, it is very difficult to study. "We have exploited an in vitro preparation of a giant synapse -called the calyx of Held, developed here at the University of Leicester in the 1990s- and its target in the auditory pathway to explore nitric oxide signalling in the... (Science Daily)

    Key Advance Toward Treatment For Most Common Adult Form Of Muscular Dystrophy  Nov 27, 2008
    Gareiss et al. Dynamic Combinatorial Selection of Molecules Capable of Inhibiting the (CUG) Repeat RNA-MBNL1 Interaction In Vitro: Discovery of Lead Compounds Targeting Myotonic Dystrophy (DM1). Journal of the American Chemical Society, 2008; DOI. (Science Daily)

    Fertility Declines with Shorter Menstrual Cycles  Nov 26, 2008
    Dr. Thomas Brodin of Malarsjukhuset in Eskilstuna, Sweden, and colleagues analyzed successful pregnancy and delivery rates in 6,271 in vitro fertilization cycles in terms of menstrual cycle length ... "The chance of delivery after (in vitro fertilization) was almost doubled for women with a menstrual cycle length longer than 34 days compared with women with a menstrual cycle length shorter than 26 days.". (MEDLINEplus)

    Cytoplasmic CXCR4 expression in breast cancer: induction by nitric oxide and correlation with lymph node metastasis and poor prognosis  Nov 24, 2008
    Our data showed a role for NO in stimulating cytoplasmic CXCR4 expression in vitro. Formation of the biomarker nitrotyrosine was also correlated with CXCR4 expression and lymph node metastasis in vivo. (BioMed Central)

    Stem cell efforts' roadblock  Nov 24, 2008
    There is no law preventing women from selling eggs to people who want to have children through in vitro fertilization ... In the United Kingdom, regulators overcame the egg shortage by allowing women to receive in vitro fertilization for half the normal price if they agreed to give half of their eggs to research ... It also makes in vitro fertilization available to couples who otherwise could not afford the procedure, which can cost about $20,000 in the United States. (San Diego Union-Tribune)

    Fall babies may be more likely to develop asthma  Nov 23, 2008
    The researchers found that several types of birth defects were more common among children conceived through in vitro fertilization, a process involving the uniting of the egg and sperm in a petri dish and implanting the embryo in the womb. The procedure was associated with twice the normal risk of certain heart defects; more than twice the risk of cleft lips, and four times the risk of some gastrointestinal abnormalities. (Globe and Mail)

    The Sorry State of American Health  Nov 21, 2008
    Also driving the infant-mortality rate are women at the other end of the economic spectrum, who take advantage of reproductive technologies such as in vitro fertilization. Such procedures boost the chances of multiple births, which in turn increase the likelihood of premature birth and consequently put babies at risk. (Time.com)

    Fertility treatments linked to certain birth defects  Nov 20, 2008
    ATLANTA, Georgia (CNN) -- A new study from the Centers for Disease Control and Prevention has found that infants born as a result of assisted reproductive technology, or ART -- such as in vitro fertilization and the use of donor eggs -- are two to four times more likely to be born with certain types of birth defects than infants conceived naturally. But, the study's lead author says, the overall risk is still relatively low. (CNN)

    LETTERS: NCT, Nov. 19, 2008  Nov 20, 2008
    These days, a union between a man and a woman need not occur in order to procreate (in vitro). Is my marriage to Mrs. Alf somehow not valid because we decided not to have any children seeing as how we each have children from previous marriages. (North County Times)

    Cellular Safety Shelters Allow TB Agent To Survive In Infected Individuals  Nov 20, 2008
    Using a recently developed in vitro assay mimicking the human host immune response, the researchers observed that Mtb uses some of its cell surface constituents to induce the transformation of macrophages (which are supposed to internalize and kill infecting bacteria), into "foamy" cells. These cells have lost their killing ability and have accumulated large amounts of lipids, the main nutrient for internalized Mtb. (Science Daily)

    Jumonjd3: A Key For Unlocking Neuronal Stem Cell Fate  Nov 20, 2008
    Giuseppe Testa and his research group have performed in vitro and in vivo experiments on cells from model organisms using innovative experimental methods based on chromatin immunoprecipitation (a technique that immortalizes the interactions between specific proteins and regions of the genome in a particular instance in the cell s life). Adapted from materials provided by. (Science Daily)

    American Chemical Society's Weekly PressPac -- Nov. 19, 2008  Nov 20, 2008
    ARTICLE #1 FOR IMMEDIATE RELEASE "Conjugated Polyelectrolyte Capsules: Light-Activated Anti-microbial Micro "Roach Motels" For a copy of the full text article, please contact Michael Bernstein at 202-872-4400. CONTACTS: Kirk Schanze, Ph.D. University of Florida Gainesville, Florida 32611-7200 Phone: 352-392-9133 Fax: 202-513-8648 Email: David Whitten, Ph.D. University of New Mexico Albuquerque, NM Phone: 505-277-5736 Fax: 505-277-1292 Email: Scientists are reporting a critical first step toward... (EurekAlert!)

    Study links fertility procedures to birth defects  Nov 19, 2008
    The procedures that increased the risk were so-called assisted reproductive techniques, like in vitro fertilization, which require doctors and technicians to work with eggs and sperm outside the body ... In 2005, about 52,000 infants were born in the United States as a result of in vitro fertilization and related techniques, according to the disease centers. (International Herald Tribune)

    Childhood Friend Has Grown Too Adult For Her Roommate - 11/19/2008  Nov 19, 2008
    Last summer I was shocked to learn that Justin and his best friend, "Beth," had had a baby girl together through in vitro. They plan to raise the child together. (FOX23.com, OK)

    Fertility Procedures Linked To Increased Risk Of Birth Defects  Nov 19, 2008
    The study found in vitro babies are two to three times more likely to be born with heart defects involving a hole in the heart, said an epidemiologist of the U.S. ... The study involved more than 250 babies conceived using in vitro fertilization, or intracytoplasmic sperm injection, a less-known technique and more than 14,000 babies conceived without using any infertility treatments ... Researchers concluded that in vitro fertilization did not significantly increase the odds of birth defects... (InjuryBoard.com)

    Nontoxic nanoparticle can deliver and track drugs  Nov 19, 2008
    Their groups found that by using human vascular smooth muscle cells in vitro, ceramide encapsulated in calcium phosphate nanoparticles reduced growth of muscle cells by up to 80 percent at a dose 25 times lower than ceramide administered freely, without damaging the cells. The calcium phosphate nanoparticles were developed by James Adair, professor of materials science and engineering, and his students. (EurekAlert!)

    Birth defects tied to fertility ways  Nov 19, 2008
    The procedures that increased the risk were so-called assisted reproductive techniques, like in vitro fertilization, which require doctors and technicians to work with eggs and sperm outside the body. The study did not include women who only took fertility drugs and did not have procedures performed. (India Times, India -- Health/Science)

    In vitro babies had more defects, study says  Nov 18, 2008
    NEW YORK - Certain birth defects multiplied and in some cases more than quadrupled when children were conceived through in vitro fertilization and similar techniques, according to the largest US study of the abnormalities. Twice the number of some heart abnormalities occurred among infants born using the techniques, called assisted reproductive technologies, in which both eggs and sperm were handled, the US Centers for Disease Control and Prevention said yesterday in the report. (Boston Globe)

    NeurogesX to Present at Lazard Capital Markets Healthcare Conference  Nov 18, 2008
    The company has evaluated these compounds in vitro and in vivo and is currently seeking development partners for these programs. SafeHarbor Statement. (PR Newswire)

    Liberals change stance with in vitro pledge  Nov 18, 2008
    A Liberal government will help more women have babies by paying the full cost of the first two attempts at in vitro fertilization and will pay out bonuses to lure more nurses into the profession and persuade retiring nurses to stay on, Premier Jean Charest announced yesterday. In unrolling his health care election platform, Charest reversed a Liberal policy of not paying for in vitro treatments on the grounds that they are not health related ... The Liberals say the new policy would increase the... (The Gazette (Montreal))

    Epigenomics AG: Ad hoc Announcement According to #15 WpHG (German Securities Trading Act)  Nov 18, 2008
    Source: Epigenomics AG. BERLIN, Germany and SEATTLE, Nov. 18, 2008 (GLOBE NEWSWIRE) -- Epigenomics AG (Frankfurt: - ) (ISIN:DE000A0BVT96) and Abbott Molecular Inc. (Abbott) today have expand their non-exclusive strategic partnership and amended their collaboration and license agreement in molecular diagnostics closed on September 25, 2007 accordingly. (Primezone Releases)

    Wonder twins  Nov 18, 2008
    One is the increased use of in vitro fertilization and fertility drugs, and the other is a hike in the number of women 35 and older giving birth ... Heather Evans, 33, underwent in vitro to have her twins, Logan and Brooke. (Erie Times-News, PA)

    Could Stem Cells Regenerate Injured Liver?  Nov 17, 2008
    (May 15, 2002) Researchers at the University of Minnesota Stem Cell Institute (SCI) have demonstrated, for the first time, the ability of adult bone marrow stem cells to differentiate in vitro as hepatocytes (liver. (Nov. (Science Daily)

    Mother Nature Vs. Infertility Treatment  Nov 15, 2008
    "If that fails, we may advance to something like in vitro fertilization (IVF)," Shaffran says. IVF involves combining eggs and sperm outside the body in a Petri dish. (CBS News)

    Disease Modeling: Mathematical Models Resolve Controversy Over Nicotine Addiction  Nov 15, 2008
    14, 2008) Human disease research produces an enormous amount of data from different sources such as animal models, high throughput genetic screening of human tissue, and in vitro laboratory experiments ... "The neurobiology of nicotine addiction is a hotly debated field. In particular, there are two contending views on how neurons and their connections in subcortical nuclei are affected by nicotine. This computer model allows us to reconcile the apparently contradictory results obtained from in... (Science Daily)

    Multiple Sclerosis: In The War Against Diseases, Nerve Cells Need Their Armor  Nov 15, 2008
    The study was carried out in mice and using in vitro cell cultures. The investigators found that myelin develops normally, but then begins to come apart. (Science Daily)

    GLG Life Tech Corporation Reports Third Quarter Results  Nov 15, 2008
    These findings added to its previous releases in 2006, which established that "stevioside and rebaudioside A are not genotoxic in vitro or in vivo". JECFA has been instrumental in paving the way for the establishment of safe and healthy food additives for over 50 years. (CCNMatthews Press Releases)

    Placebo Acupuncture Is Associated With Higher Pregnancy Rate After IVF Than Real Acupuncture  Nov 14, 2008
    11, 2008) A review of seven clinical trials of acupuncture given with embryo transfer in women undergoing in vitro fertilization (IVF) suggests that acupuncture may improve rates of pregnancy. IVF, which. (Science Daily)

    Healthier babies produced from frozen embryos: Study  Nov 14, 2008
    Babies produced from frozen embryos IVF (in Vitro Fertilization) are healthier and the likelihood of being under weight or premature are greatly reduced, a new study has revealed. . (Little About)

    Pollution tsars call for 'urgent' nanotech regulation  Nov 13, 2008
    Engineered nanoparticles to be used in consumer products should be subject to standardised toxicity tests, preferably in vitro, and regulatory constraints placed on the use of those that are not considered to meet the safety standards, said the chief executive. Did you find this article useful. (ZDNet UK)

    Freezing Ovaries Preserves Fertility, Scientists Report  Nov 13, 2008
    "If you put all those eggs in one basket, and she goes through IVF [in vitro fertilization], she can't have any better chance of pregnancy than 50 percent. If she is not pregnant from that, then she's finished.". With ovary transplantation, however, "She's got a normally functioning ovary just like she would have if she were younger. Freezing the ovary and putting it back is much more sure for the patient than egg freezing," he said. (MEDLINEplus)

    Weight-Loss Surgery May Improve IVF Outcomes  Nov 13, 2008
    NEW YORK (Reuters Health) - Preliminary findings from patients who underwent obesity surgery, also known as bariatric surgery, at Washington University in St. Louis, indicate that this procedure used to induce weight loss may improve the ability of morbidly obese women to conceive after undergoing in vitro fertilization (IVF). Meanwhile, a second study conducted at Albert Einstein College of Medicine in Bronx, New York, suggests that reproductive hormone levels are reduced in obese women and are... (MEDLINEplus)

    Boeing strike's end slow to affect Goodrich  Nov 13, 2008
    Nanogen Inc., a San Diego molecular diagnostics company, said it will collaborate with A. Menarini Diagnostics, a division of the Italian pharmaceutical company Menarini Group, to commercialize in vitro diagnostic disease kits based on Nanogen's proprietary technology. Nanogen said the deal allows it to benefit from Menarini's market presence in Europe. (San Diego Union-Tribune -- Business)

    Intraspinal implant of mesenchymal stem cells may not heal the demyelinated spinal cord  Nov 13, 2008
    "A number of in vitro and in vivo studies have reported that MSCs have differentiated into neuronal cells and Schwann cells as well as fat cells and bone cells. Our study showed that direct, intralesional injection of undifferentiated MSCs did not lead to remyelination. Once more, we found that the MSCs migrated into areas of normal tissue and were associated with axonal damage." ... Although MSCs may possess neural differentiation capabilities in vitro, their in vivo behavior is unpredictable,... (EurekAlert!)

    March of Dimes: Premature births on rise  Nov 13, 2008
    In vitro fertilization, which can lead to multiple and early births ... In recent years, there has been a jump in the number of women having multiple births because they used in vitro fertilization to become pregnant, said Dr. Larry Cousins, chief of staff at the Sharp Mary Birch Hospital for Women in San Diego. (San Diego Union-Tribune)

    AEterna Zentaris Agrees to Sell Cetrotide(R) Royalty Stream for $52.5 Million to Cowen Healthcare Royalty Partners  Nov 12, 2008
    The license agreement between AEterna Zentaris and Merck Serono was signed in 2000 and granted Merck Serono exclusive rights to market, distribute and sell Cetrotide(R) worldwide, with the exception of Japan, in the field of in vitro fertilization ... 5 million from CHRP. Under the terms of the agreement, if cetrorelix, which is currently in Phase 3 clinical trials for the treatment of benign prostatic hyperplasia, is approved for sale by European regulatory authorities in an indication other... (Canada Newswire)

    Stem Cell Solution  Nov 12, 2008
    More than 500,000 embryos created by in vitro fertilization to help couples have children are being stored. A large percentage of those embryos will never be used, because the couples have succeeded in having children, have given up or have grown too old to try. (Washington Post)

    Grandma delivers for daughter  Nov 12, 2008
    Her ovaries could produce eggs, so she and her husband tried in vitro fertilization. The embryos were implanted in Dalenberg's uterus. (Carlsbad Current Argus)

    New Hope For HIV Treatment: Cells Exhausted From Fighting HIV Infection Can Be Revitalized  Nov 12, 2008
    "To test this, we produced a molecule capable of blocking the Tim-3 signal and studied the effect that this had on CD8+ T cell function in vitro," said Mario Ostrowski, MD, Associate Professor in the Department of Immunology, University of Toronto. "We observed that blocking the Tim-3 pathway rescued those cells and restored their ability to fight off infection.". (Science Daily)

    Surrogate Grandma Fine After Triplet Birth  Nov 12, 2008
    The couple used in vitro fertilization, and embryos were implanted in Dalenberg's uterus. Distributed by Internet Broadcasting Systems, Inc. The Associated Press contributed to this report. (KIRO TV, WA)

    InVitria to Showcase its Innovative Cell Culture Components at American Society of Cell Biology Annual Meeting  Nov 12, 2008
    Innovator of animal free and defined cell culture media components will feature its productivity maximizing products at ASCB Meeting in San Francisco Dec. 13-17, 2008. Fort Collins, CO (PRWEB) November 12, 2008 -- InVitria announced today that it will showcase its innovative product line at the 48th Annual American Society of Cell Biology Meeting on Dec. 13-17 in San Francisco, CA. InVitria provides animal free and defined cell culture media components that are used by leading biopharmaceutical,... (Yahoo News -- Press Releases)

    Woman Gives Birth To Her Own Grandchildren  Nov 12, 2008
    The couple used in vitro fertilization, and embryos were implanted in Dalenberg's uterus. . (KWTX.com, TX)

    Surrogate grandmother feels fine after triplets  Nov 12, 2008
    The couple used in vitro fertilization, and embryos were implanted in Dalenberg's uterus. Type Size. (AZCentral -- News)

    Safeguard Scientifics co-leads financing  Nov 11, 2008
    ViaMetrics-E is a diagnostic procedure designed to help identify the most viable embryos with the greatest reproductive potential for in vitro fertilization. Separately, Safeguard (NYSE:SFE) said Friday it has received a notification of noncompliance with the New York Stock Exchange s continued listing standards because the closing price of its common stock averaged less than $1 per share for the 30 consecutive trading days ended Nov. 3. (Philadelphia Business Journal, PA)

    BETTER LIFE: More news on keeping your heart healthy  Nov 11, 2008
    Scientists are zeroing in on genes that could help identify which embryos created by in vitro fertilization will result in a successful pregnancy, Reuters. For now, infertility specialists often transfer more than one embryo into a woman's womb to increase her chances of having a baby. (USA Today -- Money)

    Antidepressant Affects Male Fertility  Nov 11, 2008
    "Abnormal sperm DNA integrity even affects pregnancy outcomes of the most advanced assisted reproductive technologies, such as in vitro fertilization (IVF)," she added. "In fact, it is the only male factor finding that has been shown to affect intracytoplasmic sperm injection (ICSI) results.". (Newsmax)

    Smart DNA: Programming the Molecule of Life for Work and Play  Nov 10, 2008
    For now, they play a mean game of in vitro tic-tac-toe. By Joanne Macdonald, Darko Stefanovic and Milan N. Stojanovic. (Scientific American)

    Adaltis Announces Third Quarter Financial Results  Nov 10, 2008
    MONTREAL, QUEBEC--(Marketwire - Nov. 10, 2008) - Adaltis Inc. (TSX: - ), an international in vitro diagnostic (IVD) company, today reported its third quarter 2008 financial results ... Mr. Larochelle concluded that "Adaltis, following a year of restructuring and consolidation in China, is now well positioned to reach its objective to become a China-based provider of high quality, low cost in vitro diagnostic systems, uniquely positioned to compete in China and other key emerging markets." ...... (CCNMatthews Press Releases)

    Fertility conference to address causes, treatment options  Nov 10, 2008
    "Approximately 80 percent of fertility problems can be treated through relatively simple measures, and only a small number of couples require advanced treatments such as in vitro fertilization (IVF)," said Dr. Norman Assad, ETSU associate professor of OB/GYN. "Many are concerned about the costs, but, by using a global access fee, we can make fertility treatment very affordable."The various aspects and costs of these treatment options will be discussed. Information will also be available about... (East Tennessean, TN)

    Decision to adopt children spans generations  Nov 10, 2008
    We were told, You can spend the money to do in vitro, or spend the money to adopt, and probably have a result one way or the other. It was an immediate mutual decision to adopt, Deb said. (Rapid City Journal, SD)

    Study Shows Potential Benefits of Xolair(R) in Treating Children Suffering from Moderate or Severe Persistent Allergic Asthma Inadequately Controlled With Inhaled Corticosteroids  Nov 9, 2008
    Xolair is a biologic treatment currently approved for people 12 years of age and above with moderate-to-severe persistent asthma who have a positive skin test or in vitro reactivity to a perennial aeroallergen and whose symptoms are inadequately controlled with inhaled corticosteroids ... Xolair is indicated for adults and adolescents (12 years of age and above) with moderate-to-severe persistent asthma who have a positive skin test or in vitro reactivity to a perennial aeroallergen and whose... (PR Newswire)

    What should happen in the 'Sex and the City' sequel?  Nov 8, 2008
    And they seek In vitro to have a baby and realizes how fulfilling marriage can be. Charlotte: Happy in her marriage but a bored housewife and finds comfort in a secret internet night life. (Entertainment Weekly)

    WuXi PharmaTech Signs New Collaboration Agreement With Pfizer  Nov 7, 2008
    SHANGHAI, China, Nov. 7 /Xinhua-PRNewswire/ -- WuXi PharmaTech (NYSE: WX), a leading pharmaceutical, biotechnology and medical device research and development outsourcing company with operations in China and the United States, announced today that it has signed a new three-year, in vitro ADME collaboration agreement with Pfizer ... Under the new collaboration agreement WuXi PharmaTech in partnership with Pfizer will establish ADME assays to provide in vitro screening services on compounds WuXi... (PR Newswire)

    Labopharm Reports Results for Third Quarter Fiscal 2008  Nov 7, 2008
    LAVAL, QC, Nov. 7 /CNW/ - Labopharm Inc. (TSX: DDS; NASDAQ: DDSS) today reported its results for the third quarter ended September 30, 2008. Our significant efforts to date this year have positioned us to realize a number of value-driving milestones in 2009, including the potential approval of our once-daily tramadol formulation in the U.S., the potential approval and launch of DDS-04A in the U.S., the outcome of the pivotal Phase III study for our twice-daily tramadol-acetaminophen formulation,... (Canada Newswire)

    Selective Reprogramming Of General Cells? Compounds For Stem-cell Production From Adult Cells Identified  Nov 7, 2008
    In vitro and in vivo characterizations confirmed that transduction of only two factors with simultaneous treatment with small molecules BIX and BayK was sufficient to reprogram general cells to become pluripotent stem cells. The fact that BayK doesn't act on its own, but needs the presence of BIX to exert its effect suggests that cells that are already undergoing a form of reprogramming, perhaps caused by injury, might be more susceptible to it. (Science Daily)

    Springer to collaborate with American Society for Reproductive Medicine  Nov 6, 2008
    It publishes original contributions and review articles covering human and animal data relevant to the process of in vitro fertilization and embryo replacement. Leading experts present the latest advances in a variety of topics, including assisted reproductive technologies, diagnostic and therapeutic procedures affecting the treatment of infertility, genetics of early gestation, laboratory sciences affecting the diagnosis and treatment of infertility, pharmacology and technology of assisted... (EurekAlert! -- Business News)

    Scientists clone from frozen mice  Nov 5, 2008
    Viable eggs, sperm and embryos are already retrieved from the frozen state for use in in vitro fertilisation (IVF). Bookmark with. (BBC News -- Health)

    Study Sheds Light on Painkillers' Heart Risk  Nov 5, 2008
    "We found a significant correlation between the degree of inhibition in vitro [in the laboratory] of whole blood cox-2, but not whole blood cox-1," said the report by researchers in Spain and Italy. Cox-1 and cox-2 are different forms of cyclooxygenase, an enzyme whose activity increases inflammation and pain. (MEDLINEplus)

    Debunking infertility myths  Nov 5, 2008
    "In IVF, fertilisati 00004000 on occurs outside the womb. In vitro the egg is fertilised in a glass. The man's sperm and the woman's egg are fertilised in a laboratory dish and the resulting embryo is then transferred to the woman's uterus. Depending upon the kind of problem in both the sexes, various permutations and combinations of sperms, eggs, embryo etc. can be used to find the desired solution," informs Delhi-based infertility expert Dr. Sonia Malik. 1. (India Times, India)

    Compound Stabilizes Main Natural Suppressor Of Tumors  Nov 4, 2008
    Furthermore, computer simulations and in vitro experiments have allowed the scientists to demonstrate the functionality of the complex. The design and analysis of the compound has also involved the collaboration of the biologist Vera Martos, Javier de Mendoza s team, and the researcher Margarita Men;ndez at the "Consejo Superior de Investigaciones Cient;ficas". (Science Daily)

    New journal shows half-broken gene is enough to cause cancer  Nov 4, 2008
    PathoGenetics will focus on both in vitro and in vivo studies on the cascade of events leading from gene mutations or genomic rearrangement to disease. The discovery of novel molecular and metabolic pathways relevant to disease pathogenesis will be given specific emphasis. (EurekAlert!)

    Spontaneous transformation of human granulosa cell tumours into an aggressive phenotype: a metastasis model cell line  Nov 4, 2008
    Moreover, the invasive capacity of these cells was determined using the in vitro invasion assay ... During in vitro culture, the advanced passage KGN cells grew 2-fold faster than the early passage cells, as determined by the population doubling assay ... KGN cells cultured in vitro acquire an aggressive phenotype, which was confirmed by the analysis of cellular activities and the expression of biomarkers. (BioMed Central)

    Genetic noise control via protein oligomerization  Nov 4, 2008
    We have developed a fully stochastic model for the positive feedback control of a single gene, as well as a pair of genes (toggle switch), integrating quantitative results from previous in vivo and in vitro studies. In particular, we explicitly account for the fast binding-unbinding kinetics among proteins, RNA polymerases, and the promoter/operator sequences of DNA. We find that the overall noise-level is reduced and the frequency content of the noise is dramatically shifted to the... (BioMed Central)

    Role of Drug Transporters and Drug Accumulationin the Temporal Acquisition of Drug Resistance  Nov 4, 2008
    It remains unclear whether drug resistance in vitro occurs at clinically relevant doses of chemotherapy drugs and whether both the onset and magnitude of drug resistance can be temporally and causally correlated with the enhanced expression and activity of specific drug transporters. To address these issues, MCF-7 cells were selected for survival in increasing concentrations of doxorubicin (MCF-7DOX-2), epirubicin (MCF-7EPI), paclitaxel (MCF-7TAX-2), or docetaxel (MCF-7TXT). (BioMed Central)

    Sundown on Colorado fundamentalists (145)  Nov 4, 2008
    So, all of these folks have decided that in vitro fertilization is wrong if creation begins at conception ... Embroyo's are created via the in vitro procedures, and these same embroyo's are routinely destroyed -- not via abortion which they oppose, but via clinical destruction. (Salon)

    Promoter Hypermethylation-mediated Inactivationof LRRC4 in Gliomas  Nov 3, 2008
    It was found that LRRC4 promoter activity is strongly suppressed after treatment with SssI methylase in vitro. Furthermore, LRRC4 promoter methylation was observed by methylation-specific PCR in two glioma cell lines and all 30 primary glioma specimens, but not in normal brain tissue. (BioMed Central)

    Negative Ads Mark Campaign Season's End  Nov 2, 2008
    CBS Evening News: Campaign Commercials Distorting Opponents' Records Becoming Commonplace In State, National Races. Attack Of The Campaign Ads. (CBS News)

    Anadys Pharmaceuticals Announces Single Dose Safety and Pharmacokinetics Results for ANA598 in Healthy Volunteers  Nov 2, 2008
    -- In a poster titled "In Vitro Studies Demonstrate that Combinations of Antiviral Agents that Include HCV Polymerase Inhibitor ANA598 have the Potential to Overcome Viral Resistance", Anadys will present the results of in vitro studies that show ANA598 to be synergistic with interferon-alpha, the protease inhibitor telaprevir (VX-950), and the nucleoside polymerase inhibitor PSI-6130 (the active agent of R7128). These studies also show that ANA598 retains activity against mutants known to... (PR Newswire)

    Surrogate baby from Indian mother leaves for Japan  Nov 2, 2008
    Manji's saga has exposed the pitfalls of international commercial surrogacy or what has been called "wombs for rent" in which surrogate mothers are impregnated in vitro with the egg and sperm of couples who are unable to conceive on their own. Manji's father, Ikufumi Yamada, 48, and his then-wife Yuki, 45, came to India in 2007 in search of a surrogate mother. (International Herald Tribune)

    The Adoption Option  Nov 1, 2008
    She underwent treatments, including surgeries and in vitro fertilization, but still couldn t get pregnant. In May 2004, they began filling out paperwork to apply for adoption. (Logan Herald Journal, UT)

    Designer babies  Oct 31, 2008
    This can lead to either the termination of a pregnancy, or if analyzed at a pre-implantation stage when using In Vitro Fertilization (IVF), can enable the pregnancy to be created using only non-disease bearing genes. British scientists last week developed a "genetic MoT" test, which offers a universal method of screening embryos for diseases using a new technique of karyomapping, which is more efficient than previous processes. (CNN -- International)

    Improved Rodent Trials Can Speed Cancer Drug Development, Expert Suggests  Oct 31, 2008
    Cancer drug development is a multistep process that involves in vitro tests, animal studies often with rodent models of disease and human clinical trials. Inadequately designed rodent studies have led to missteps and delays in previous drug development programs. (Science Daily)

    Simple chemical procedure augments therapeutic potential of stem cells  Oct 31, 2008
    "Jeff hasn't tested the altered MSCs inside animals, and that's really the gold-standard, but his in vitro data looks promising.". . (EurekAlert!)

    Healing Process Found To Backfire In Lung Patients  Oct 29, 2008
    Starting with basic research findings from in vitro cell and experimental animal studies, they were then able to demonstrate, in patients with IPF, that higher IaI serum levels were associated with less ability to take up oxygen, thus worsening the patients' condition. The researchers say there are at least two reasons why this study is important. (Science Daily)

    New topical approach to treating nail fungus circumvents problems with current therapy  Oct 29, 2008
    NB-002 kills both active spores and developing hyphae, an additive effect that lessens the fungi's ability to survive in human tissue, said James R. Baker, Jr., M.D., founder and chairman of NanoBio Corp. Studies conducted in vitro demonstrate that NB-002 has robust antifungal activity against all organisms that cause nail fungus, including Trichophyton rubrum, T. mentagrophytes, Epidermophyton floccosum, Microsporum canis and Candida albicans. NanoBio scientists credit the topical lotion's... (EurekAlert!)

    Sigma-Aldrich Releases WTA2, a Transplex Whole Transcriptome Amplification Technology for Degraded RNA Samples  Oct 28, 2008
    Optimized for formalin-fixed and paraffin-embedded tissue samples, WTA2 is the second addition to the patent-pending suite of WTA products designed to study RNA in vitro. "Sigma-Aldrich is committed to bringing best-in-class technologies to the genomic research community," said Helge Bastian, Vice President of Marketing for Sigma-Aldrich's Research Biotech Business Unit. (PR Newswire)

    Newly Discovered Mechanism Can Explain Beckwith-Wiedemann Syndrome  Oct 28, 2008
    18, 2002) Scientists from Johns Hopkins and Washington University School of Medicine in St. Louis have discovered that in vitro fertilization (IVF) appears to be associated with a rare combination of birth. (June 22, 2005) Further confirmation of a link between 'imprinting' disorders and assisted reproduction techniques (ART) was provided to the 21st annual conference of the European Society of Human Reproduction and. (Science Daily)

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