Cases Of Liver Cancer Reduced In Younger Population Vaccinated For Hepatitis B Sep 18, 2009
17, 2009) A 20-year follow-up study revealed a dramatic drop in liver cancer cases among 6- to 19-year-olds who were vaccinated for the hepatitis B virus at birth, according to a study published online September 16 in the Journal of the National Cancer Institute. See also. (Science Daily)
Overdiagnosis Since Introduction Of Prostate Cancer Screening Sep 15, 2009
14, 2009) The introduction of prostate-antigen screening, or PSA, has resulted in over 1 million additional men over the last 23 years being diagnosed and treated for prostate cancer most of whom were likely overdiagnosed, researchers reported in a new study published online August 31 in the Journal of the National Cancer Institute. See also. (Science Daily)
Day-care dividend debunked Sep 14, 2009
WHERE TO FIND IT: Journal of the National Cancer Institute, Sept. 9. ELIZABETH COONEY. (Boston Globe)
Aggressive prostate cancer linked to an STD Sep 12, 2009
All the men were enrolled in the Physician's Health Study, according to the report published this week in the Journal of the National Cancer Institute. They found that roughly one in five men had been infected with trichomonas at some point in his life. (CNN -- Health)
U.S. Food and Drug Administration Clears Vermillion's OVA1(TM) Test to Determine Likelihood of Ovarian Cancer in Women with Pelvic Mass Sep 12, 2009
(1) Journal of the National Cancer Institute, Vol. 98, No. 3, February 1, 2006. (2) Greenlee RT, Murray T, Bolden S, Wingo PA. Cancer statistics, 2000. (PR Newswire)
Link Found Between Common Sexual Infection And Risk Of Aggressive Prostate Cancer Sep 11, 2009
The study appears online on September 9, 2009, on the Journal of the National Cancer Institute website and will appear in a later print edition ... "Prospective Study of Trichomonas vaginalis Infection and Prostate Cancer Incidence and Mortality: Physicians' Health Study," Jennifer R. Stark , Gregory Judson, John F. Alderete, Vasanthakrishna Mundodi, Ashwini S. Kucknoor, Edward L. Giovannucci, Elizabeth A. Platz, Siobhan Sutcliffe, Katja Fall, Tobias Kurth, Jing Ma, Meir J. Stampfer, Lorelei A.... (Science Daily)
Melanosome Dynamics And Sensitivity Of Melanoma Cells To Chemotherapy Sep 11, 2009
10, 2009) Manipulating the functions of melanosomes--the organelles in pigment-producing cells--may enhance the activity of anticancer drugs used against melanoma, according to a new study published online August 24 in the Journal of the National Cancer Institute. See also. (Science Daily)
Family, Friends Influence Breast Cancer Decisions Sep 5, 2009
Women were also more likely to choose mastectomy if they themselves played a major role in driving the decision instead of the doctor, according to the study published in the Aug. 31 online edition of the Journal of the National Cancer Institute. The study examined factors influencing a woman's choice between a mastectomy to remove the entire breast or breast-conserving surgery, which involves removing only the tumor and is followed by radiation treatments. (MEDLINEplus)
Study: PSA test leads to needless diagnoses Sep 2, 2009
The study was published online in the August 31 issue of the Journal of the National Cancer Institute. The researchers acknowledge that prostate cancer screenings can indeed save lives; however, their study was conducted to highlight the majority of men who did not benefit from the test. (CNN)
Too Many Cancer Tests Yield False Positives Sep 2, 2009
Two studies released Monday -- one looking at and the other at -- appearing in the Journal of the National Cancer Institute, show that brings false positives and the costs of emotional anguish and sometimes unnecessary treatment. "The fact that it is a surprise to so many physicians and so many patients is a symptom of the debate taking place now regarding health care reform," said Dr. Thomas Schwenk, a family physician with the University of Michigan, commenting on the prostate cancer study. (ABC News)
Adding Breast Exam to Mammogram - Is It Worth It? Sep 2, 2009
NEW YORK (Reuters Health) - Adding a clinical breast exam to screening mammography increases breast cancer detection rates, but it also increases rates of falsely positive results, Canadian researchers report in the Journal of the National Cancer Institute ... SOURCE: Journal of the National Cancer Institute, online August 31, 2009. (MEDLINEplus)
Prostate Cancer Over-Diagnosed Sep 2, 2009
Since the PSA screening test came into use in 1986, federal government data show that the number of prostate cancer cases in the United States has risen substantially, said the report in the Aug. 31 online issue of the Journal of the National Cancer Institute ... SOURCES: H. Gilbert Welch, M.D., professor, medicine, Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth Medical School, Hanover, N.H.; Judd Moul, M.D., director, Duke Prostate Center, Durham, N.C.; Aug. 31, 2009,... (MEDLINEplus)
Many with prostate cancer suffer no ill effects Sep 1, 2009
whose study appears in the Journal of the National Cancer Institute. More than 1 million of those were treated, they found. (MSNBC -- Health)
Prostate Cancer Diagnosed Earlier, Race Gap Narrows Aug 29, 2009
NEW YORK (Reuters Health) - Men with prostate cancer are being diagnosed at a younger age and earlier stage today than in years past, and the racial disparity in stage at diagnosis has decreased significantly, researchers report today in the Journal of the National Cancer Institute ... SOURCE: Journal of the National Cancer Institute, August 27, 2009. (MEDLINEplus)
High Serum Insulin Levels And Risk Of Prostate Cancer Aug 24, 2009
23, 2009) Elevated insulin levels in the normal range appear to be associated with an increased risk of prostate cancer, according to a new study published online August 21 in the Journal of the National Cancer Institute. See also. (Science Daily)
Fecal DNA Methylation Detects Gastric And Colorectal Cancers Aug 24, 2009
23, 2009) A preliminary evaluation of methylation of two gene promoters in fecal DNA showed promise as a noninvasive method to detect colorectal and gastric cancers, according to a new study published online August 21 in the Journal of the National Cancer Institute. See also. (Science Daily)
Why Racial Profiling Persists in Medical Research Aug 22, 2009
The controversy resurfaced in July with the publication of a study in the Journal of the National Cancer Institute (JNCI) in which researchers analyzed more than 19,000 patients who participated in clinical trials involving treatments for a variety of cancers. The paper found that all other factors being equal, black patients had on average a significantly lower cancer survival rate than whites. (Time.com)
JNCI news brief: High serum insulin levels and risk of prostate cancer Aug 22, 2009
Elevated insulin levels in the normal range appear to be associated with an increased risk of prostate cancer, according to a new study published online August 21 in the Journal of the National Cancer Institute ... The Journal of the National Cancer Institute is published by Oxford University Press and is not affiliated with the National Cancer Institute ... Attribution to the Journal of the National Cancer Institute is requested in all news coverage. (EurekAlert!)
Public Overestimates Benefits Of Cancer Screening, Survey Finds Aug 19, 2009
18, 2009) A public survey conducted in Europe found that the vast majority of people overestimate the life-saving benefits of breast and prostate cancer screening, according to a new study published online August 12 in the Journal of the National Cancer Institute. See also. (Science Daily)
Health grenade of capping care Aug 12, 2009
Calculations published last week in the Journal of the National Cancer Institute put the annual cost of extending the life of every American cancer patient by one year at the same price pro rata at $US440 billion. If you use the same formula for Australia, it's about $35 billion. (Sydney Morning Herald -- Opinion)
In U.S., No Comeback Seen for Hormone Therapy Aug 11, 2009
D., M.P.H., vice president, epidemiology, American Cancer Society; April 22, 2009, presentation, American Association for Cancer Research annual meeting, Denver; American Cancer Society, news release, Feb. 2, 2009; Oct. 1, 2008, European Heart Journal, online; Sept. 23, 2008, Journal of the National Cancer Institute. HealthDay. (MEDLINEplus)
Antibody Linked To Chemotherapy Drug Inhibits Ovarian Cancer In Lab Aug 9, 2009
8, 2009) A novel anticancer agent, consisting of a monoclonal antibody linked to a chemotherapy drug, showed substantial antitumor activity in ovarian cancer cell lines and in mice, according to a study published online July 29 in the Journal of the National Cancer Institute. See also. (Science Daily)
Older Cancer Patients Have More Frailty Than Other Seniors Aug 9, 2009
8, 2009) Older people with a history of cancer are more likely to have disabilities and be frail and vulnerable than older adults who have not had cancer, according to a study in the Journal of the National Cancer Institute, published online July 29. See also. (Science Daily)
Breast Cancer Hormone Receptor Status And Risk Of A Second Primary Tumor Aug 2, 2009
1, 2009) Women with hormone receptor (HR) negative first tumors have twice as much risk for developing a second breast cancer as women with HR-positive tumors, according to a study published online July 9 in the Journal of the National Cancer Institute. See also. (Science Daily)
EphA2-targeted therapy delivers chemo directly to ovarian cancer cells Jul 30, 2009
Using the EphA2 protein as a molecular homing mechanism, chemotherapy was delivered in a highly selective manner in preclinical models of ovarian cancer, the researchers report in the July 29 issue of the Journal of the National Cancer Institute. EphA2 is attractive for such molecularly targeted therapy because it has increased expression in ovarian and other cancers, including breast, colon, prostate and non-small cell lung cancers and in aggressive melanomas, and its expression has been... (EurekAlert!)
Thalidomide Does Not Improve Survival In Small Cell Lung Cancer, Study Finds Jul 21, 2009
ScienceDaily (July 20, 2009) Treating patients with thalidomide in combination with chemotherapy for small cell lung cancer (SCLC) did not improve their survival but did increase their risk of blood clots, according to a new study published online July 16 in the Journal of the National Cancer Institute. See also. (Science Daily)
Thalidomide lung cancer 'failure' Jul 17, 2009
But the Journal of the National Cancer Institute reported this is not the case for small cell lung cancers and that it increases the risk of blood clots. However, experts said the drug is showing promise on other cancers. (BBC News -- Health)
Diagnosis a factor in cancer care racial gap Jul 14, 2009
Another recent study, however, that appeared in the Journal of the National Cancer Institute, found that African Americans who developed breast, ovary, and prostate cancer had worse outcomes even when they received the same care. That suggested that "there is something that 'tracks' with African ancestry" for these three diseases, a co-author of that study, Dr. Kathy S. Albain of Loyola University Medical Center in Maywood, Illinois, told Reuters Health earlier this month. (MSNBC -- Health)
Studies Shed Light On Racial Disparities In Cancer Survival Jul 14, 2009
ScienceDaily (July 13, 2009) Black women diagnosed with breast cancer have a greater chance of dying from the disease than white women, according to a new study published online July 7 in the Journal of the National Cancer Institute. See also. (Science Daily)
Elevated Insulin Linked To Increased Breast Cancer Risk Jul 13, 2009
An earlier study linking insulin levels with breast cancer risk was carried out by Einstein researchers and was published in the January 7, 2009 issue of the Journal of the National Cancer Institute. In the most recent study, Dr. Kabat and his colleagues analyzed data on 5,450 women enrolled in the Women's Health Initiative, a large multicenter study investigating the influence of a number of factors on women's health. (Science Daily)
Risk Of Breast Cancer And A Single-nucleotide Polymorphism Jul 11, 2009
ScienceDaily (July 10, 2009) The single-nucleotide polymorphism (SNP) known as 2q35-rs13387042 is associated with increased risk of estrogen receptor (ER) -positive and -negative breast cancer, according to a study published online July 1 in the Journal of the National Cancer Institute. See also. (Science Daily)
Cancer Gap Between Whites, Blacks May Be Biological in Part Jul 9, 2009
The study appeared online Tuesday in the Journal of the National Cancer Institute. "The elimination of socioeconomic and health-care access disparities must be a priority in the United States. However, [the study] demonstrates that further investigation of race- or ethnicity-associated differences in primary tumor biology is also important," Dr. Lisa Newman, director of the Breast Cancer Center at the University of Michigan Comprehensive Cancer Center in Ann Arbor, said in the news release. (MEDLINEplus)
Cancer Survivors At Greater Risk Of Birth Complications; Special Monitoring Needed Jul 9, 2009
(July 5, 2006) Women who survive childhood cancer are more likely to suffer premature menopause, according to a study in the July 5 issue of the Journal of the National Cancer Institute. Risk factors include. (Science Daily)
Genetic factors implicated in survival gap for breast, ovarian or prostate cancer Jul 9, 2009
Dawn Hershman, M.D, M.S., a Columbia University Medical Center oncologist whose research is dedicated to examining racial and ethnic disparities in cancer outcome and in cancer survivorship, was the senior author of the research published online by the Journal of the National Cancer Institute (JNCI). The study analyzed patient records from clinical trials going back as far as 1974 conducted by the Southwest Oncology Group (SWOG). (EurekAlert!)
Why Are African-Americans Less Likely To Survive Certain Cancers? Jul 8, 2009
But the study, published in the Journal of the National Cancer Institute, found there was no statistically significant association between race and survival for lung and colon cancers, leukemia, lymphoma or myeloma. "The good news for African Americans is that for most common cancers, they have the same survival rates as all other races," Albain said. (Science Daily)
Race a factor in cancer deaths gap: study Jul 8, 2009
The analysis was the first to find that the disparities remain even when African-American patients receive identical medical treatment and other socioeconomic factors are controlled, said the authors of the study published in the Journal of the National Cancer Institute. Despite the strong association found between race and survival for the three gender-related cancers, the study did not identify such links for lung and colon cancer, lymphoma, leukemia and multiple myeloma. (Yahoo! Asia News)
Study: Biological factors may affect cancer survival Jul 8, 2009
"There is good news and puzzling news in our results," said Kathy Albain of Loyola University, whose findings were published online Tuesday by the Journal of the National Cancer Institute. "When there's a level playing field with the same quality of care, African-Americans survive just as well as other races from some of our most common cancers, which is reassuring news and points us nationally toward a need to make sure there is quality of care and equal access to all. But for prostate, ovarian... (AZCentral -- News)
Prostate Cancer Patients Disease Free After Five Years Likely To Be Disease Free After 10 Years Jul 4, 2009
13, 2008) Breast cancer survivors continue to have a substantial risk of disease recurrence after five years of systemic therapy, according to a study in the Journal of the National Cancer Institute. Among. (Science Daily)
High Fat Intake Linked to Pancreatic Cancer Jul 3, 2009
High intake of dietary fats from red meat and dairy products was associated with an increased risk of pancreatic cancer, according to a new study published online June 26 in the Journal of the National Cancer Institute. This study was undertaken because research relating fat intake to pancreatic cancer was inconclusive. (Newsmax)
How Much Is Life Worth? The $440 Billion Question Jul 1, 2009
ScienceDaily (June 30, 2009) The decision to use expensive cancer therapies that typically produce only a relatively short extension of survival is a serious ethical dilemma in the U.S. that needs to be addressed by the oncology community, according to a commentary published online June 29 in the Journal of the National Cancer Institute ... 29, 2008) The cost of cancer care for elderly Medicare patients varies by tumor type, stage at diagnosis, phase of care, and survival, according to a new... (Science Daily)
Eating Animal Fat May Lead to Pancreatic Cancer Jun 30, 2009
The report is published online June 26 in the Journal of the National Cancer Institute ... June 24, 2009, Journal of the American Medical Association; June 26, 2009, Journal of the National Cancer Institute, online. (MEDLINEplus)
Fatty diet may lead to pancreatic cancer Jun 29, 2009
The research, published in the Journal of the National Cancer Institute, included more than 500,000 people who had completed in 1995 or 1996 diet questionnaires for whom information about pancreatic cancer was available about six years later. The research results showed that people consuming large amounts of saturated fat were 36 percent more likely to suffer from the disease. (Xinhuanet, China)
Animal fat ups pancreatic cancer risk Jun 27, 2009
The research has been published on online June 26 in the Journal of the National Cancer Institute. To reach the cocnlsuion, Rachael Z Stolzenberg-Solomon, PhD, of the Division of Cancer Epidemiology and Genetics at the National Cancer Institute in Bethesda, Md, and colleagues analyzed a cohort of over 500,000 people from the National Institutes of Health - AARP Diet and Health Study. (India Times, India)
Animal fats pancreas cancer link Jun 27, 2009
The Journal of the National Cancer Institute paper found those who had the most animal fats in their diet had a higher risk of developing the cancer ... Writing in the Journal of the National Cancer Institute, the researchers led by Dr Rachel Stolzenberg-Solomon, said: "We observed positive associations between pancreatic cancer and intakes of total, saturated, and monounsaturated fat overall, particularly from red meat and dairy food sources. "We did not observe any consistent association with... (BBC News)
Promising Biomarker And Candidate Tumor Suppressor Gene Identified For Colorectal Cancer Jun 26, 2009
ScienceDaily (June 25, 2009) Researchers have identified a new candidate tumor suppressor gene in colorectal cancer and examined its use as a potential biomarker in stool samples, according to a new study published online June 17 in the Journal of the National Cancer Institute. See also. (Science Daily)
Hodgkin Lymphoma Survivors Have Increased Risk Of Stroke And Transient Ischemic Attack Jun 26, 2009
ScienceDaily (June 25, 2009) Patients treated for Hodgkin lymphoma with radiation therapy have a substantially higher risk of stroke, according to a new study published June 17 online in the Journal of the National Cancer Institute ... In the February 7 issue of the Journal of the National Cancer Institute, researchers. (Science Daily)
Prostate Cancer Test Improves Prediction Of Disease Course Jun 24, 2009
The study, involving 10,627 men, is reported in the June 9 online edition of the Journal of the National Cancer Institute. This test should help physicians and their patients predict the likely course of the individual s disease, said Matthew R. Cooperberg, MD, MPH, lead investigator of the study. (Science Daily)
Study Finds Possible Genetic Indicator of Colorectal Cancer Jun 20, 2009
In the new study, published online June 17 in the Journal of the National Cancer Institute, researchers in the Netherlands, Belgium and the United States looked for genetic signs that appeared in cancerous colorectal cells and tissue but not in those from healthy people ... D., director, CHS National Israeli Cancer Control Center, Haifa, Israel; June 17, 2009, Journal of the National Cancer Institute. (MEDLINEplus)
Hodgkin Lymphoma Survivors Face Stroke Risk Jun 19, 2009
Patients treated for Hodgkin lymphoma with radiation therapy have a substantially higher risk of stroke, according to a new study the Journal of the National Cancer Institute published online. The study was undertaken because information on clinically verified stroke and transient ischemic attack (TIA), or a "mini stroke," following Hodgkin lymphoma is limited. (Newsmax)
Radiation May Raise Stroke Risk After Hodgkin's Jun 19, 2009
The study appears online June 17 in the Journal of the National Cancer Institute ... SOURCE: Journal of the National Cancer Institute, news release, June 17, 2009. (MEDLINEplus)
Cancer Diagnosis May Tax Physical, Mental Health Jun 16, 2009
The study appears in the June 9 online edition of the Journal of the National Cancer Institute ... SOURCE: Journal of the National Cancer Institute, news release, June 9, 2009. (MEDLINEplus)
Still Too Few Women in Cancer Trials Jun 16, 2009
In the report, published in the July 15 issue of the journal Cancer, the researchers looked at all original clinical cancer research published in 2006 in five major cancer journals (the Journal of Clinical Oncology, the Journal of the National Cancer Institute, The Lancet Oncology, Clinical Cancer Research and Cancer) and three major general medical journals (the New England Journal of Medicine, the Journal of the American Medical Association and The Lancet). The importance of including women in... (MEDLINEplus)
Goopy Ear Wax And Unpleasant Body Odors Signal Breast Cancer Risk Jun 3, 2009
19, 2006) Having breast implants is not associated with an increased risk of cancer overall, a new study reports in the Journal of the National Cancer Institute. Implants were associated with a decrease in. (Science Daily)
Childhood Cancer Survivors Have Persistent High Risk For Cancer Throughout Their Lives Jun 1, 2009
ScienceDaily (May 31, 2009) Childhood cancer survivors have a persistent and high risk for a second primary cancer throughout their lives, according to a new study published in the Journal of the National Cancer Institute ... (July 5, 2006) Women who survive childhood cancer are more likely to suffer premature menopause, according to a study in the July 5 issue of the Journal of the National Cancer Institute. (Science Daily)
New Broad-spectrum Vaccine To Prevent Cervical Cancer Induces Strong Responses In Animals May 31, 2009
ScienceDaily (May 31, 2009) Mice and rabbits immunized with a multimeric-L2 protein vaccine had robust antibody responses and were protected from infection when exposed to human papillomavirus (HPV) type 16 four months after vaccination, according to a new study published in the May 26 online issue of the Journal of the National Cancer Institute. See also. (Science Daily)
Risks Remain for Childhood Cancer Survivors May 28, 2009
A study that appears online May 26 in the Journal of the National Cancer Institute went further than earlier studies by following people from birth through age 79 ... SOURCE: Journal of the National Cancer Institute, news release, May 26, 2009. (MEDLINEplus)
Parents Of Boy With Cancer Agree To Chemo May 27, 2009
A study that appears online May 26 in the Journal of the National Cancer Institute went further than earlier studies by following people from birth through age 79. The researchers analyzed data on more than 47,000 people who had been diagnosed with cancer before the age of 20. (CBS News)
Cancer risk for child survivors May 27, 2009
The Journal of the National Cancer Institute study blames potent therapies rather than genetics, and is the first to show the risk is so long-term. The study of 50,000 also found those diagnosed after 1975 appeared to have a slightly higher risk of cancer as treatments became more aggressive. (BBC News -- Health)
Letters for Friday, May 15, 2009 May 16, 2009
g-man wrote on May 15, 2009 5:22 PM:" Hey getalife, looks like the brain damaged one is YOU...your name fits.....there is this cool thing called reading, not only that, there is this cooler thing called reading comprehension. try it....................................................A new study reveals that Medical Marijuana can be an effective treatment for cancer, that is the word announced by doctors in Germany who concluded that this clarification of the mechanism of cannabinoid action may... (Lihue Garden Island, HA)
Women With Previous Abnormal Cervical Cells At Higher Risk For Recurrence And Invasive Cancer May 15, 2009
The large, population-based study, which appears in the May 12 online issue of the Journal of the National Cancer Institute, sheds new light on the long-term risks of subsequent abnormal cell growth or invasive cancer, and should help in the development of follow-up treatment guidelines for women with a history of treatment for abnormal cells. "We now have a much more clear idea of the risks of recurrent abnormal cells and invasive cervical cancer over time after treatment of these cells," said... (Science Daily)
Formaldehyde Raises Risk of Deadly Cancers May 14, 2009
A study of more than 25,000 workers at industrial plants that produced formaldehyde and formaldehyde resin found workers with the highest exposures had a 37 percent increased risk of death compared to those with the lowest exposure levels, they reported in the Journal of the National Cancer Institute. They said exposure to the chemical raised the risk of several specific cancers, including Hodgkin's lymphoma, multiple myeloma, and myeloid leukemia -- the type most often associated with chemical... (MEDLINEplus)
Abnormal Cells in Cervix Raise Cancer Risk May 14, 2009
"We now have a much more clear idea of the risks of recurrent abnormal cells and invasive cervical cancer over time after treatment of these cells," said Joy Melnikow of the University of California Davis, whose study appears in the Journal of the National Cancer Institute. The condition, known as cervical intraepithelial neoplasia (CIN), can progress to cancer. (MEDLINEplus)
Study links formaldehyde to more common cancers May 13, 2009
Workers with the highest peak exposures were 37% more likely to die from any blood or lymphatic cancer, and 78% more likely to die from myeloid leukemia a cancer of the white blood cells compared to those with lowest levels, according to the study, published online today in the Journal of the National Cancer Institute. Highly exposed workers also were nearly four times more likely to die of Hodgkin lymphoma, which affects immune cells, the study shows. (USA Today -- News)
Review finds conflicts of interest in many cancer studies May 11, 2009
These journals included the New England Journal of Medicine; JAMA; the Lancet; the Journal of Clinical Oncology; the Journal of the National Cancer Institute; Lancet Oncology; Clinical Cancer Research; and CANCER.. Of the 1,534 cancer studies identified in these journals, 29 percent had conflicts of interest that were apparent from review of published author declarations and authorship lists (including industry funding, consulting fees to authors, co-authorship by industry employees, etc. (EurekAlert!)
In this market, cancer has competition May 10, 2009
The nation's death rate from cancer has declined since the early 1990s, in part because of better testing, treatment and awareness about major cancers such as those that affect the breast, colon and lung, according to an annual report about national trends that appeared in the December edition of the Journal of the National Cancer Institute. Though the death rate has declined, the number of new cases continues to increase as the nation's population grows. (AZCentral -- Business)
