Same Dose Of Anthracycline Is Not Safe For Everyone, Study Finds Aug 5, 2008
New models can help physicians calculate the epirubicin dose associated with a 5 percent risk of cardiotoxicity for individual patients, researchers report in the July 29 online issue of the Journal of the National Cancer Institute. See also. (Science Daily)
Lapatinib Reduces Brain Metastases In Mouse Model Of Metastatic Breast Cancer Aug 4, 2008
4, 2008) Lapatinib reduces the number of large brain metastases in a mouse model of metastatic breast cancer, relative to untreated mice, researchers report in the July 29 online issue of the Journal of the National Cancer Institute. See also. (Science Daily)
Two Different Breast Cancer Screening Strategies Are Equally Effective, Study Fiinds Aug 3, 2008
2, 2008) An organized population-based breast cancer screening program in Norway and an approach to screening that relies on physician- and self-referrals in Vermont are equally sensitive for detecting cancer, researchers report in the July 29 online issue of the Journal of the National Cancer Institute. But the recall rate for abnormal mammograms was lower in Norway. (Science Daily)
Mitochondrial DNA Copy Number Associated With Risk Of Kidney Cancer Aug 2, 2008
A lower mtDNA copy number was associated with an increased risk of renal cell cancer in a case-control study, researchers report in the July 29 online issue of the Journal of the National Cancer Institute. See also. (Science Daily)
Air pollution in Beijing a threat to Olympic spectators Aug 2, 2008
But the finding, published in the Journal of the National Cancer Institute, is certainly not encouraging news. After all, adult survivors of childhood cancer are at elevated risk of developing cardiovascular disease, lung problems and second malignancies, compared with the general public. (Globe and Mail)
Modified Salmonella Slows Tumor Growth Jul 31, 2008
ScienceDaily (July 30, 2008) Attenuated Salmonella bacteria engineered to express the Fas ligand (FasL) accumulate in tumors and reduce their growth, researchers report in the July 29 online issue of the Journal of the National Cancer Institute. See also. (Science Daily)
2 Breast Cancer Screening Strategies Prove Effective Jul 31, 2008
A study in the July 29 online issue of the Journal of the National Cancer Institute finds that a traditional physician- and self-referral screening strategy held up well against the Norway approach, in which the government sends letters to all women in a specific age range inviting them to have a screening mammogram. The Norway program aims for women to be screened every two years, while the U.S.-based "opportunistic screening" strategies advise women to have annual screening mammograms. (MEDLINEplus)
Smoking risk of cancer survivors Jul 30, 2008
The study, in the Journal of the National Cancer Institute, pinpoints three types of childhood cancer - Hodgkin's lymphoma, soft tissue sarcomas and Wilms' tumour - which are known to carry an increased risk of further tumours due to the form of radiotherapy and chemotherapy used to treat them. The researchers found that smoking was most common among people who had been treated for these cancers when children - nearly a quarter of the 10,000 former cancer sufferers surveyed. (BBC News -- UK)
Mammogram screening methods comparable Jul 30, 2008
NEW YORK (Reuters Health) - The mammography screening policy used in the U.S. is equally effective as one used in Europe in detecting breast cancer, according to a report in the Journal of the National Cancer Institute ... SOURCE: Journal of the National Cancer Institute, August 2008. (Reuters India)
Overweight Elderly Americans Contribute To Financial Burdens Of U.S. Health Care System, Study Finds Jul 28, 2008
29, 2008) The cost of cancer care for elderly Medicare patients varies by tumor type, stage at diagnosis, phase of care, and survival, according to a new study in the Journal of the National Cancer Institute. (May 29, 2008) Men who are overweight or obese are much more likely need a hip replacement for osteoarthritis than men who are of normal weight, finds new research. (Science Daily)
Does Too Much Sun Cause Melanoma? Jul 25, 2008
8, 2005) Two new studies in the February 2 issue of the Journal of the National Cancer Institute have found that sun exposure may have a beneficial influence on some types of cancer. One study found an. (Science Daily)
Researcher warns of brain cancer risk from cellphones Jul 25, 2008
Children should use cellphones only for emergencies as their brains are still developing, according to the head of a prominent U.S. cancer research institute. (Yuriko Nakao/Reuters). (International Herald Tribune)
Cell Phone Use and Cancer Jul 24, 2008
Some Studies Suggest Health Concerns From Cellular Phones. Some medical professionals are suggesting limiting cell phone use based on a potential risk of developing cancer and other health problems. (Suite101.com)
Cancer researcher warns of cellphone risks Jul 24, 2008
The largest published study, which appeared in the Journal of the National Cancer Institute in 2006, tracked 420,000 Danish cellphone users, including thousands that had used the phones for more than 10 years. It found no increased risk of cancer among those using cellphones. (AZCentral -- News)
Recent Genetic Discoveries Don't Improve Prediction of Breast Cancer Jul 15, 2008
But when applied to existing models that use clinical factors, such as age and family history, to predict an individual's risk, they do not appear to change the prediction, according to a study in the July 8 online issue of the Journal of the National Cancer Institute. Someone who is at high risk for breast cancer may choose to pursue more aggressive preventive strategies than a person at low risk, who may suffer side effects that far outweigh the benefits. (MEDLINEplus)
Higher Education Associated With Greater Gains In Mortality Reduction From Common Cancers Jul 13, 2008
A study published in the July 8 online issue of the Journal of the National Cancer Institute shows that more highly educated individuals had mortality reductions in nearly all of these cancers, while less educated individuals had a mortality reduction in only one of the cancer types. See also. (Science Daily)
Risk, From a Broader Perspective Jul 13, 2008
New risk charts in a paper last month in The Journal of the National Cancer Institute provide a broader perspective than most of the risk calculators available on the Internet, because they cover the risks for 10 causes of death and for all causes combined, while differentiating by age and among smokers, nonsmokers and former smokers. At first glance, it may appear that smokers and nonsmokers die of heart disease at the same rate, but they do not. (Atlanta Journal-Constitution -- Health)
Low Iron Levels Cut Cancer Risk in Men with Peripheral Arterial Disease Jul 13, 2008
According to the findings, published in the July 8 issue of the Journal of the National Cancer Institute, participants who underwent phlebotomy were 37 percent less likely to develop cancer over four-plus years of follow-up than those who didn't have their blood drawn for iron removal. The findings were consistent with previous studies done on animals. (MEDLINEplus)
College-Educated Fare Better When Cancer Strikes Jul 13, 2008
The report was published July 8 in the online edition of the Journal of the National Cancer Institute. In the study, Jemal's team collected data on cancer deaths between 1993 and 2001 from the U.S. National Center for Health Statistics. (MEDLINEplus)
HEALTH BLOG: Easy to digest nutrition news briefs Jul 8, 2008
Women who don't get regular Pap smears are 2 1/2 times more likely to be diagnosed with cervical cancer than women who do and five times more likely to be diagnosed with advanced disease, according to a new Swedish in the Journal of the National Cancer Institute. HealthDay provides. (USA Today -- Money)
Statins vs. Advanced Prostate Cancer Jun 27, 2008
SOURCES: Platz, E. Journal of the National Cancer Institute, Dec. 20, 2006; vol 98: pp 1819-1825. News release, Journal of the National Cancer Institute. (Yahoo News -- Prostate Cancer)
Identification Of A Tumor Suppressor Gene Associated With Patient Outcome In Neuroblastoma Jun 27, 2008
ScienceDaily (June 27, 2008) Expression of the CHD5 gene is frequently down-regulated in neuroblastomas, and patients whose tumors lacked CHD5 expression were more likely to have shorter event-free and overall survival compared with patients whose tumors expressed CHD5, according to a study in the June 24 issue of the Journal of the National Cancer Institute ... JNCI Journal of the National Cancer Institute, 2008; DOI. (Science Daily)
Multiple Regions Of Chromosome 8 Found To Be Associated With Different Cancers Jun 27, 2008
ScienceDaily (June 26, 2008) A recently discovered, but not yet understood, section of chromosome 8, called 8q24, may contain at least five distinct regions that are associated with different cancers, according to a study in the June 24 issue of the Journal of the National Cancer Institute ... JNCI Journal of the National Cancer Institute, 2008; DOI. (Science Daily)
NSAID Use Not Associated With Reduction In Melanoma Risk Jun 27, 2008
ScienceDaily (June 26, 2008) The use of nonsteroidal anti-inflammatory drugs (NSAIDs) is not associated with a reduction in the risk of melanoma, according to the results of a large cohort study in the June 24 issue of the Journal of the National Cancer Institute ... JNCI Journal of the National Cancer Institute, 2008; DOI. (Science Daily)
Intestinal Proteins May Be Effective Anti-Tumor Antigens Jun 27, 2008
ScienceDaily (June 26, 2008) Mice immunized with an intestinal protein developed fewer lung and liver metastases following injection with colon cancer cells than unvaccinated animals, according to a study in the June 24 issue of the Journal of the National Cancer Institute ... JNCI Journal of the National Cancer Institute, 2008; DOI. (Science Daily)
Different Type Of Colon Cancer Vaccine Reduces Disease Spread, Scientists Show Jun 27, 2008
Reporting online June 24, 2008 in the Journal of the National Cancer Institute, Scott Waldman, M.D., Ph. D., professor and chair of Pharmacology and Experimental Therapeutics at Jefferson Medical College of Thomas Jefferson University and his co-workers have shown that mice immunized with an intestinal protein developed fewer lung and liver metastases after injection with colon cancer cells than did control animals that were not immunized. (Science Daily)
Researchers: Colon Cancer Vaccine on the Horizon Jun 26, 2008
A study published in the Journal of the National Cancer Institute detailed how mice were immunized with the protein and subsequently infected with colon tumors. These mice had fewer tumors spread to the lung and liver than usual. (Fox News)
Vaccine Stops Colon Cancer's Spread in Mice Jun 26, 2008
The report is published in the June 24 online issue of the Journal of the National Cancer Institute. In the experiments, Waldman's team engineered a vaccine that expressed GCC, and injected it into mice that had been given colon cancer cells. (MEDLINEplus)
Rates of diabetes rise dramatically Jun 25, 2008
Mice immunized with the protein, guanylyl cyclase C, and then infected with colon tumors had fewer tumors spread to the lung and liver, the researchers at Thomas Jefferson University in Philadelphia reported in the Journal of the National Cancer Institute. Many cancer vaccines are in the early stages of development, but researchers are struggling to find the right targets, called antigens. (Boston Globe)
Study shows coffee lowers heart risk but not cancer deaths Jun 17, 2008
And a 2005 study found that coffee could help prevent the most common type of liver cancer, according to the Journal of the National Cancer Institute. Karen Collins, a nutrition adviser with the American Institute for Cancer Research, says the key to coffee's health benefits is its antioxidants. (USA Today)
Low Melatonin Associated with Increased Risk of Breast Cancer in Postmenopausal Women Jun 17, 2008
This research was recently published in the Journal of the National Cancer Institute. Adapted from materials provided by , via , a service of AAAS.. (Science Daily)
Coffee Drinkers Have Slightly Lower Death Rates Jun 17, 2008
23, 2005) Two new studies in the February 16 issue of the Journal of the National Cancer Institute examine the effects of coffee consumption on the incidence of liver and colorectal cancers. One study found. (Science Daily)
Anti-estrogen Drug Therapy Reduces Risk Of Invasive Breast Cancer In Older Women Jun 17, 2008
The results of the randomized controlled trial will be published in the Journal of the National Cancer Institute. See also. (Science Daily)
Ladies, walk it off (the angst too) Jun 14, 2008
" "They have yellow ones now," my friend informs me. It figures. We are power walking through Rosedale. In this moneyed Toronto neighbourhood, everything can be what you want it to be. Trees are art. Addresses are pedigree. Cars are sex. We don't break our stride. We are breathing deeply, and not from annoyance. The arms pump. The feet step quickly. What we encounter and observe is all part of the enjoyment and bemusement of walking through the city, through its ravines and the deep divides of... (Globe and Mail)
Radiation, Chemo Costs Drive Cancer Spending in U.S. Jun 13, 2008
While the availability of therapy is good news for patients, the added costs will strain public health insurance plans such as Medicare, the researchers reported in the Journal of the National Cancer Institute. For instance, the cost of treating a lung cancer patient for a year rose by $7,139 between 1991 and 2002, to $39,891, after adjusting for inflation, Joan Warren of the National Cancer Institute in Bethesda, Maryland and colleagues found. (MEDLINEplus)
Accuracy of Mammography Varies by Facility Jun 12, 2008
In the study, reported in the Journal of the National Cancer Institute, significant variation in specificity, the number of women testing negative for cancer; positive predictive value, the number with positive results who were actually positive; and the likelihood of cancer among women referred for biopsy; was noted between facilities ... SOURCE: Journal of the National Cancer Institute, June 18, 2008. (MEDLINEplus)
Bone Drug Prevents One Type of Breast Cancer Jun 12, 2008
So-called estrogen-receptor-positive breast cancer is the most common type and women who took Eli Lilly and Co's Evista were 55 percent less likely to develop this type of cancer than women taking a placebo, the researchers reported in the Journal of the National Cancer Institute. Evista, known generically as raloxifene, is already approved for reducing the risk of breast cancer in women past menopause who have osteoporosis. (MEDLINEplus)
Researchers Update Risk-of-Death Charts Jun 12, 2008
The charts, to be published in the June 10 online issue of the Journal of the National Cancer Institute show an American's risk of dying from a given cause in the next 10 years. The charts are grouped by age, sex and smoking status. (MEDLINEplus)
Two girls found shot to death Jun 11, 2008
While the availability of therapy is good news for patients, the added costs will strain public insurance plans such as Medicare, researchers reported in the Journal of the National Cancer Institute. (Reuters). (Boston Globe)
Death risk chart shows smokers should beware Jun 11, 2008
In this week's Journal of the National Cancer Institute, Schwartz's team combed government death statistics to update easy-to-read charts comparing the odds of death in the coming 10 years for different ages and diseases. Don't miss this on msnbc. (MSNBC -- Health)
Raloxifene Cuts Risk of Certain Type of Breast Cancer Jun 11, 2008
June 10, 2008, Journal of the National Cancer Institute, online) ... The study, published in the June 10 online issue of the Journal of the National Cancer Institute, was funded by Eli Lilly and Co., which makes Evista. (Health-Finder)
Smoking Shortens Lives 10 Years Jun 11, 2008
In this week's Journal of the National Cancer Institute, Schwartz's team combed government death statistics to update easy-to-read charts comparing the odds of death in the coming 10 years for different ages and diseases. The charts intended for posting in doctors' offices stress age, gender and smoking status, not more personal risk factors such as a history of cancer in the family. (Newsmax)
Osteoporosis Drug Helps Prevent Breast Cancer Jun 11, 2008
The results of the randomized controlled trial will be published in the June 10 online issue of the Journal of the National Cancer Institute. Breast cancer is the most common cancer among women. (Newsmax)
'Smoking cuts life span by 5 years' Jun 11, 2008
According to a mortality risk chart released Tuesday in the US Journal of the National Cancer Institute, smoking cigarettes has the same effect as cutting the life span by close to five years. "The effect of smoking on the chance of dying is similar to the effect of adding five to 10 years of age," the study said. (India Times, India -- Health/Science)
Estrogen Helps Drive Distinct, Aggressive Form Of Prostate Cancer May 30, 2008
The findings are published in the May 27 online edition of the Journal of the National Cancer Institute ... JNCI Journal of the National Cancer Institute, Advance Access published on May 27, 2008 DOI. (Science Daily)
Antioxidant Supplements May Lessen Benefit Of Radiation And Chemotherapy May 29, 2008
ScienceDaily (May 28, 2008) Cancer patients should avoid the routine use of antioxidant supplements during radiation and chemotherapy because the supplements may reduce the anticancer benefits of therapy, researchers concluded in a commentary published online in the Journal of the National Cancer Institute. See also. (Science Daily)
Paclitaxel Plus Chemo Improves Outcomes in Early Breast Cancer May 29, 2008
The study was published in the May 27 online issue of the Journal of the National Cancer Institute. In an accompanying editorial, researchers at Memorial Sloan-Kettering Cancer Center in New York City reviewed several trials that examined the effects of adding taxanes (a family of drugs that include paclitaxel) to existing adjuvant therapy for breast cancer. (MEDLINEplus)
Cancer Patients Should Steer Clear of Antioxidants May 29, 2008
In the new review, reported in the May 27 online edition of the Journal of the National Cancer Institute, Lawenda and colleagues examined studies into antioxidants and cancer therapy. The researchers found that only three studies on radiation and antioxidants relied on randomized controlled trials, which are considered the best way to compare medical treatments. (MEDLINEplus)
Vitamin D Status Not Associated with Lower Prostate Risk May 29, 2008
The study was published in the May 27 online issue of the Journal of the National Cancer Institute. "Results from this large prospective study of men who underwent standardized prostate cancer screening in the context of a screening trial do not support the hypothesis that higher serum vitamin D status is associated with decreased risk of prostate cancer," the study authors wrote. (MEDLINEplus)
Antioxidants May Undermine Cancer Therapy May 28, 2008
Although research looking at antioxidant use during cancer treatment has been on-going on for nearly two decades, it remains a controversial topic, note Dr. Brian D. Lawenda, from the Navel Medical Center in San Diego, California, and colleagues in their article in the Journal of the National Cancer Institute ... SOURCE: Journal of the National Cancer Institute, online May 27, 2008. (Newsmax)
Brain tumors still rare; cellphone link is unproven May 26, 2008
A Danish study published two years ago in the Journal of the National Cancer Institute followed 420,095 cellphone users for 20 years and found no connection. However, a new meta-analysis - a study grouping the results of several studies together - published this month in the International Journal of Oncology did find a connection between heavy mobile phone use and gliomas, as well as acoustic neuroma, a type of benign tumor that can lead to hearing loss. (Boston Globe)
SAN JOSE MERCURY NEWS: There's one more reason to require girls to take PE May 17, 2008
The study, published in the Journal of the National Cancer Institute, asked 65,000 nurses ages 24 to 42 to detail their physical activity since they were 12 years old. The women who reported exercising regularly as teens and young adults were 23 percent less likely to develop pre-menopausal breast cancer. (Fresno Bee -- Opinion)
Girls, Young Women Can Cut Risk Of Early Breast Cancer Through Regular Exercise May 15, 2008
Journal of the National Cancer Institute. May 13, 2008 (advance online publication). (Science Daily)
Black Rectal Cancer Patients Less Likely to Get Chemo, Radiation May 15, 2008
The findings were published in the May 13 online issue of the Journal of the National Cancer Institute. "Although there wasn't a discrepancy between African-Americans and whites in the rates of consultation with an oncologist, we found a large discrepancy in the receipt of chemotherapy. This is very important. We knew that African-Americans were not receiving chemotherapy for rectal cancer at the same rates as white Americans, and it was contributing to their increased mortality. Now we have a... (MEDLINEplus)
High-Tech Imaging No Better for Diagnosing Head/Neck Cancers May 15, 2008
The analysis, published online May 13 in the Journal of the National Cancer Institute, also found that the imaging technique incorrectly identified normal tissue as being cancerous 13 percent of the time. The sensitivity and accuracy of FDG-PET compared with the two other common imaging techniques used -- magnetic resonance imaging (MRI) and computed tomography (CT) -- appears to be slightly better, but researchers said the differences were not statistically significant. (MEDLINEplus)
Family History Raises Breast Cancer Risk for Life May 15, 2008
NEW YORK (Reuters Health) - Women who have a sister diagnosed with breast cancer have a higher than average risk of also developing the disease, and this increased risk will persist for the rest of their lives, epidemiologists in Sweden report in the Journal of the National Cancer Institute ... SOURCE: Journal of the National Cancer Institute, May 2009. (MEDLINEplus)
New Source of hope stoke victims May 14, 2008
Women who were physically active as teens and young adults were 23 percent less likely to develop premenopausal breast cancer than women who grew up sedentary, researchers report today in the Journal of the National Cancer Institute. -- Edited from wire reports. (The Augusta Chronicle)
Physical activity may cut risk of breast cancer May 14, 2008
Dr. Colditz's study, published yesterdayin the U.S.-based Journal of the National Cancer Institute, is the largest analysis to date of the effects of exercise on pre-menopausal breast cancer. Researchers from Washington University and Harvard University evaluated nearly 65,000 women who filled out questionnaires on their level of physical activity at various periods of their lives, starting from age 12. (Globe and Mail)
Teenage Girls Who Exercise Have Less Breast Cancer Risk Later On May 14, 2008
Writing in the Journal of the National Cancer Institute, lead author Dr, Graham Colditz says the study indicates that "sustained physical activity from adolescence through the adult years" lowers a woman's chances of developing breast cancer. . (KWTX.com, TX)
Exercise in teenage may reduce risk of breast cancer May 14, 2008
BEIJING, May 14 (Xinhuanet) -- Regular exercise in teenage and young adulthood may help cut a women's risk of developing premenopaausal breast cancer, according to a report Wednesday in the Journal of the National Cancer Institute. The study finds that women who were physically active as teens and young adults are 23 percent less likely to develop breast cancer than those who grew up sedentary. (Xinhuanet, China)
Exercising May Lower Breast Cancer Risk May 14, 2008
Women who were physically active as teens and young adults were 23 percent less likely to develop premenopausal breast cancer than women who grew up sedentary, researchers report Wednesday in the Journal of the National Cancer Institute ... Writing in the Journal of the National Cancer Institute, lead author Dr. Graham Colditz said the study indicates that "sustained physical activity from adolescence through the adult years" lowers a woman's chances of developing breast cancer. (Click2Houston, TX)
Getting To The Roots Of Breast Cancer May 2, 2008
ScienceDaily (May 1, 2008) The lesson learned in eradicating dandelions from your yard could apply in treating breast cancer as well, said researchers from Baylor College of Medicine in Houston in a report that appears online April 29 in the Journal of the National Cancer Institute. See also. (Science Daily)
Medicare 5-year cancer bill tops $21.1 bln: study May 2, 2008
The research by Robin Yabroff of the National Cancer Institute in Bethesda, Maryland, and colleagues, which appears in the Journal of the National Cancer Institute, is intended to offer policymakers a tool to prepare as the U.S. population expands and ages. Joseph Lipscomb, a health policy researcher at Emory University in Atlanta, said the study is the first to combine cost estimates and survival data to arrive at long-term national estimates for 18 of the most common types of cancers in the... (Reuters)
Medicare Costs Soar for Cancer Care May 2, 2008
The findings are published in the April 29 issue of the Journal of the National Cancer Institute. For the study, Yabroff's team estimated the cost of cancer care among 718,907 cancer patients and compared that to 1,623,651 people without cancer. (MEDLINEplus)
Screening Delay Tied to Advanced Cervical Cancer May 2, 2008
Their findings appear in the Journal of the National Cancer Institute ... SOURCE: Journal of the National Cancer Institute, April 29th online 2008. (MEDLINEplus)
