* ANALYSIS: Hunger strikes can raise ethics issues for doctors Nov 24, 2008
When ketone levels are too high, it can lead to ketoacidosis, a potentially lethal condition, he said. By supplementing the body with glucose, such as through intravenous infusion, the bodys metabolism returns to normal and ketone levels drop very quickly, he said. (Taipei Times, Taiwan -- World)
New study data: JANUVIA (sitagliptin) Nov 22, 2008
JANUVIA should not be used in patients with type 1 diabetes or for the treatment of diabetic ketoacidosis. JANUVIA has not been studied in combination with insulin. (EurekAlert!)
CFC Corner: November is American Diabetes Month Nov 13, 2008
Conditions associated with diabetes include hyperglycemia, hypoglycemia, ketoacidosis and celiac disease, each requiring special treatment to regulate a person insulin and glucose levels. Having diabetes also increases your risk for many serious complications including: heart disease (cardiovascular disease), blindness (retinopathy), nerve damage (neuropathy), and kidney damage (nephropathy). (The Dolphin, CT)
World Diabetes Day Nov 14: Caring for children and adolescents ... Nov 13, 2008
Diabetic Ketoacidosis (DKA), a build-up of excess acids in the body as a result of uncontrolled diabetes, is a major cause of death in children with Type-1 diabetes. DKA can be prevented with early diagnosis and proper medical care. (Newstrack India)
Bayhill Therapeutics and the Juvenile Diabetes Research Foundation announce research collaboration Oct 31, 2008
Short-term effects of poor glucose control include diabetic ketoacidosis, which is a condition that can lead to coma. Long-term effects include elevated glucose levels, blindness, kidney disease, heart disease, peripheral vascular disease and stroke. (EurekAlert! -- Business News)
Hyperglycemic Emergencies Oct 5, 2008
Management of Diabetic Ketoacidosis and Hyperosmolar Coma ... Diabetic Ketoacidosis ... Diabetic ketoacidosis (DKA) is mostly associated with DM type 1 but can occur with DM type 2. (Suite101.com)
Living with diabetes: Kids can still be kids Oct 3, 2008
Over time, elevated blood sugars can lead to a serious condition called ketoacidosis (the blood becoming acidic), which can eventually lead to a coma or death. I always felt it was like having a newborn child, Dee Richardson, Timmy s mother, said about her son s diagnosis. (Concord Journal, MA)
Terminally Ill Rodents With Type 1 Diabetes Restored To Full Health With Single Dose Of Leptin Aug 27, 2008
The animals that received the leptin gene began producing excessive amounts of leptin, which reversed all the measurable consequences of type 1 diabetes including weight loss, hyperglycemia and ketoacidosis, a potentially fatal condition that develops when the body doesn't have enough insulin to meet basic metabolic requirements. Much of the effect was mediated by complete suppression of the high glucagon levels, said Dr. Xinxin Yu, assistant instructor of internal medicine and lead author of... (Science Daily)
Diabetes camp set for Thursday Aug 6, 2008
Some of the days events will include: Jeopardy: Diabetic Ketoacidosis, Olympic Course, Geo-Caching, Guest Lecturer, Water Games, Making Healthy Snacks and of course fishing. Families of the children with diabetes will join in at 4 p.m. for dinner and a fun filled evening. (Pocatello Idaho State Journal, ID)
Hospital rise for child diabetes Jun 23, 2008
Last year, 3,317 were admitted to hospital with the potentially coma-inducing complication diabetic ketoacidosis compared to 2,617 in 2002 ... Diabetic ketoacidosis can be the first obvious sign of unchecked diabetes in a child, with symptoms such as sluggishness and fatigue, weight loss, stomach pain and vomiting ... Once diagnosed, children with type I diabetes use insulin injections to manage their blood sugar levels - but if they are very poorly-controlled, ketoacidosis can arise again. (BBC News -- UK)
New Data From Head-to-Head Study Confirms Once-Daily Levemir(R) is as Effective as Glargine over a 24-Hour Period in Subjects with Type 2 Diabetes Jun 9, 2008
Inadequate dosing or discontinuation of treatment may lead to hyperglycemia and, in patients with type 1 diabetes, diabetic ketoacidosis. Insulin may cause sodium retention and edema, particularly if previously poor metabolic control is improved by intensified insulin therapy. (PR Newswire)
Acid Problem Common at Diabetes Diagnosis in Kids May 16, 2008
Known as diabetic ketoacidosis, the condition occurs when insulin levels in the body are so low that virtually no sugar is able to enter cells and provide energy ... The key finding is that in the United States close to 30 percent of children with type 1 diabetes and 10 percent of those with type 2 diabetes have potentially life-threatening ketoacidosis at the time of diagnosis ... "While poverty, barriers in access to care and lower parental educational attainment further increase the risk,... (MEDLINEplus)
Girl's death probed after parents rely on prayer Mar 28, 2008
An autopsy showed Madeline Neumann died Sunday from diabetic ketoacidosis, a condition that left too little insulin in her body, Everest Metro Police Chief Dan Vergin said. She had probably been ill for about a month, suffering symptoms such as nausea, vomiting, excessive thirst, loss of appetite and weakness, the chief said Wednesday, noting that he expects to complete the investigation by Friday and forward the results to the district attorney. (MSNBC -- Health)
Cops: Family Prayed Despite Knowing Daughter Gravely... Mar 28, 2008
died Sunday from diabetic ketoacidosis, an ailment that left her with too little insulin in her body. Investigators said she probably had been ill for about 30 days, suffering from symptoms such as nausea, vomiting, excessive thirst, loss of appetite and weakness. (Fox News)
Parents Didn't Expect Daughter to Die During Prayer Mar 27, 2008
Everest Metro Police Chief Dan Vergin has said an autopsy determined Madeline died from diabetic ketoacidosis, an ailment that left her with too little insulin in her body. She had probably been ill for about 30 days, suffering symptoms such as nausea, vomiting, excessive thirst, loss of appetite and weakness, he said. (Fox News)
Praying Did Not Help Little Girl Survive Mar 27, 2008
Everest Metro police Chief Dan Vergin said autopsy results confirm Madeline Neumann died from diabetic ketoacidosis, a condition that develops when a persons body has too little insulin ... Marathon County Medical Examiner John Larson said diabetic ketoacidosis prevents the body from absorbing nutrients. (eFluxMedia)
State of Alaska and Eli Lilly and Company Reach Agreement to Settle Zyprexa Lawsuit Mar 26, 2008
"A trial always involves significant time and resources, especially a two-phase trial like this one that posed additional legal hurdles. A settlement helps us get back to what we want to focus on as a company: developing important new medications through research and partnerships with doctors and patients. "We appreciate all the time and energy the jury invested over more than three weeks in such a complex case," Armitage added. The agreement involves no admission of wrongdoing on Lilly's part.... (PR Newswire)
Police: Family prayed instead of getting medical aid for girl Mar 26, 2008
Vergin said an autopsy determined the girl died from diabetic ketoacidosis, an ailment that left her with too little insulin in her body, and she had probably been ill for about 30 days, suffering symptoms like nausea, vomiting, excessive thirst, loss of appetite and weakness. The girl's parents, Dale and Leilani Neumann, attributed the death to "apparently they didn't have enough faith," the police chief said. (Chippewa Falls Chippewa Herald, WI)
Family files suit in case of Mini-Cassia jail inmate death Mar 5, 2008
Montoya, 36, died from complications associated with diabetic ketoacidosis, the coroner told the family ... Ketoacidosis usually develops slowly, when acids build up in the blood and poison the body, but vomiting indicates that the condition is life-threatening. (Burley South Idaho Press, ID)
Joslin study finds restricting insulin doses increases mortality risk Feb 27, 2008
Warning signs include: unexplained elevations in A1c levels; repeated problems with diabetic ketoacidosis (DKA), which can be fatal; extreme concerns about weight and body shape; change in eating patterns; unusual pattern of intense exercise (sometimes associated with frequent hypoglycemia); and ammenorrhea (skipping monthly menstrual cycles). Raising awareness of the impact of insulin restriction among clinicians who treat type 1 diabetes is extremely important so that they can make appropriate... (EurekAlert!)
FDA Advisory Committee Supports Efficacy and Safety of Zyprexa(R) Long-Acting Injection (LAI) for Schizophrenia Treatment Feb 7, 2008
Hyperglycemia, in some cases extreme and associated with ketoacidosis or hyperosmolar coma or death, has been reported in patients treated with atypical antipsychotics, including Zyprexa. While relative risk estimates are inconsistent, the association between atypical antipsychotics and increases in glucose levels appears to fall on a continuum and olanzapine appears to have a greater association than some other atypical antipsychotics. (PR Newswire)
Recovery means uncovering a past buried for years Feb 3, 2008
Ketoacidosis: High levels of acids known as ketones build up in the blood when the body is burning fat instead of sugar and carbohydrates to get energy ... Seizures: Dehydration, hyperglycemia and ketoacidosis might be responsible for the increased risk of seizures in anorexics and bulimics. (Daytona Beach News Journal)
Illness Presents Diabetics with Special Challenges Jan 23, 2008
High ketone levels can lead to ketoacidosis, which can lead to coma or death. Unless told otherwise by your doctor, don't stop taking insulin or other medications. (MEDLINEplus)
FSA scientist derides New Year detox diets Dec 29, 2007
This is ketosis, and not to be confused with ketoacidosis, which is harmful. Next it burns and sheds all the toxins in 00002515 the body which are held in the tissues for years. (Telegraph.co.uk)
Twins on a medical odyssey after a diagnosis of diabetes Nov 21, 2007
By the time she reached the emergency room at 3 a.m., she was in diabetic ketoacidosis, a life-threatening condition in which extremely high blood sugar causes an imbalance in blood chemicals. "Her potassium was very low, and her glucose was very high," said her father, Dr. Rick Newman, a plastic surgeon. (International Herald Tribune)
More Black Children Dying from Diabetes Nov 17, 2007
Many of these deaths are due to acute complications such as diabetic ketoacidosis, in which insulin levels are too low ... All these deaths are from diabetic ketoacidosis, Deeb said. (MEDLINEplus)
Pledge to turn off Diabetes in children Nov 14, 2007
Yet diabetes in children is often diagnosed late, when the child has Diabetic Ketoacidosis (DKA), or it is misdiagnosed completely. In many parts of the world, insulin, the main life-saving medication that children with diabetes need to survive, is not available (or is available but remains inaccessible for reasons of economy, geography or constraints on supply). (Zee News)
Late Diagnosis Increases Risk in Diabetic Children Nov 8, 2007
Diabetic ketoacidosis was one of the significant causes of death; six patients died of diabetic ketoacidosis, a serious complication of diabetes. Ketoacidosis is caused by the build-up of ketones, which are by-products of fat breakdown. (MEDLINEplus)
Hundreds expected for annual Step Out to Fight Diabetes Oct 14, 2007
Conditions associated with Type 1 diabetes include hyperglycemia, hypoglycemia, ketoacidosis and celiac disease. Most Americans with diabetes have Type 2, which makes them insulin-resistant, meaning their bodies cannot properly use the hormone. (North County Times)
Diabetes doesnt stop her Sep 25, 2007
She was quickly diagnosed with diabetic ketoacidosis after having her blood sugar tested at 1127. Golden said a normal level is between 70 and 120. (Odessa American, TX)
Pekin family walks for juvenile diabetes Sep 18, 2007
He recently spent a week in the hospital for ketoacidosis, a complication of the disease. Kohlton's 10-year-old sister, Kjirsten, has held lemonade stands and raffles to support diabetes research that have netted more than 700 in the last two years. (Pekin Times, IL)
China kids at higher risk of diabetes Sep 7, 2007
Type-I diabetics need to take insulin on a daily basis, or, diabetes can lapse into a life-threatening diabetic coma, known as Diabetic Ketoacidosis. Type-I diabetics usually choose clinic treatment rather than hospitalisation since expenses to cure diabetes is not covered by social medical insurance in China. (India Times, India -- Health/Science)
Chinese children at higher risk for diabetes Sep 6, 2007
Type I diabetics need to take insulin on a daily basis, or, diabetes can lapse into a life-threatening diabetic coma, known as Diabetic Ketoacidosis. Shen Shuixian, chief of the endocrinology department in children's hospital of Fudan University, appeals to public attention for the young diabetics. (Xinhuanet, China)
Mysteries of autoimmune diseases unravel Sep 4, 2007
Reagan was in a state of diabetic ketoacidosis, a dangerous condition caused by extremely high blood sugar. After 31/2 days in the hospital, she was able to go home to begin life with diabetes. (USA Today)
Thereare a lot of diabetes myths out there; what's true? Aug 26, 2007
This is because any infection interferes with your blood glucose management, putting you at risk of high blood glucose levels and, for those with type 1 diabetes, an increased risk of ketoacidosis. Myth No. 7 Insulin causes atherosclerosis (hardening of the arteries) and high blood pressure. (Pittsburgh Post-Gazette, PA)
Pathologist Testifies In Boy's Death Aug 11, 2007
Under questioning by Deputy District Attorney Jerry Chang, Reiber said a contributing factor to Raijon's death was ketoacidosis - a dangerous buildup of acids in the blood - most likely as a result of starvation. Reiber told the prosecutor that he had ruled out that the child had diabetes, which could be another reason for the buildup. (San Francisco Chronicle -- Crime)
Flu symptoms mask an outbreak of diabetes-1 Aug 8, 2007
If left undiagnosed, it can lead to severe stomach pain and vomiting, a sign of ketoacidosis, where uncontrolled blood glucose and ketone levels cause dehydration and a build-up of toxic acids. Of the 16 cases at the Children's Hospital at Westmead, six had developed ketoacidosis and were admitted to the intensive care unit, Dr Howard said. (Sydney Morning Herald -- Australia)
Bad flu season linked to diabetes spike Aug 8, 2007
If left untreated it can cause uncontrolled blood glucose and ketone levels, called ketoacidosis, that leads to a coma. Howard says his hospital would normally see six or seven children a month at this time of year, with only the occasional case of life-threatening ketoacidosis ... But this month the hospital diagnosed 17 cases and six of these required intensive care for diabetic ketoacidosis. (ABC Science Online)
Teacher: Insulin denied in jail Jun 26, 2007
" In jail, Robinson went two days with no medication for his diabetes and then was given the wrong medicine for another five days, which put him in the hospital for three days, two in leg irons and the third as a free man. A Grady doctor said Robinson suffered a "life-threatening episode of ketoacidosis," which the American Diabetic Association defines as a serious condition that can lead to diabetic coma. "He's lucky to be alive," one of Robinson's doctors wrote in a memo to an Atlanta judge.... (Atlanta Journal-Constitution)
Blogger unmasked, court case upended May 31, 2007
Less than six weeks later, the boy died of diabetic ketoacidosis, said Mulvey, who described the condition as "diabetes gone haywire.". Lindeman, a graduate of Yale University and Columbia University's College of Physicians and Surgeons, is board-certified in general pediatrics and pediatric pulmonary medicine, according to the Natick Pediatrics website. (Boston Globe)
Efficacy and safety of Aripiprazole as adjunctive therapy in major depressive disorder May 23, 2007
Hyperglycemia and diabetes mellitusHyperglycemia, in some cases associated with ketoacidosis, coma, or death, has been reported in patients treated with atypical antipsychotics including aripiprazole. Patients with diabetes should be monitored for worsening of glucose control; those with risk factors for diabetes should undergo baseline and periodic fasting blood glucose testing. (EurekAlert!)
Six-Week Investigational Study In Adults With Major Depressive Disorder Evaluates The Effectiveness of Adjunctive Aripiprazole Therapy With Antidepressants May 22, 2007
Prescribing should be consistent with the need to minimize TD. If signs and symptoms appear, discontinuation should be considered since TD may remit, partially or completely - Cerebrovascular adverse events (eg, stroke, transient ischemic attack), including fatalities, have been reported at an increased incidence in clinical trials of elderly patients with dementia-related psychosis treated with aripiprazole - Hyperglycemia and diabetes mellitus-Hyperglycemia, in some cases associated with... (PR Newswire)
FDA Approves Astrazeneca's Once-Daily Seroquel XR(TM) Extended-Release Tablets for the Treatment of Schizophrenia May 18, 2007
Hyperglycemia, in some cases extreme and associated with ketoacidosis, hyperosmolar coma, or death, has been reported in patients treated with atypical antipsychotics, including quetiapine. The relationship of atypical use and glucose abnormalities is complicated by the possibility of increased risk of diabetes in the schizophrenic population and the increasing incidence of diabetes in the general population. (PR Newswire)
FDA Approves JANUMET for Type 2 Diabetes Apr 3, 2007
JANUMET should not be used in patients with type 1 diabetes or for the treatment of diabetic ketoacidosis. The FDA approved JANUMET based upon clinical data including sitagliptin plus metformin as separate tablets. (Playfuls.com)
Out-of-court settlement reached in suit filed over death in jail Mar 22, 2007
According to the lawsuit, Denise died of a pulmonary edema, after she developed ketoacidosis while she was in the jail. The suit claimed guards at the jail oted Denise was lethargic,' not able to speak coherently,' unbalanced,' and had trouble breathing in the 24 hours prior to her death. (Jefferson City News Tribune, MO)
Classic twists Mar 17, 2007
People have an instinctive under-standing of childbirth that they don't have of, say, diabetic ketoacidosis. There seemed to be something peculiarly emotive about childbirth that's not present in cardiac bypass grafting. (Guardian Unlimited -- Books)
* Doctors expecting a wave of patients looking to diet Mar 6, 2007
"But losing weight at that rate could result in dangerously elevated levels of uric acid, electrolyte imbalance and ketoacidosis.". "Others tell me they really want to lose the weight, but then balk at making return appointments," he added. (Taipei Times, Taiwan -- World)
Q&A on diabetes Feb 28, 2007
Sometimes a condition called diabetic ketoacidosis is present which is life-threatening and results in hospitalization. In contrast, people with type 2 diabetes often have no symptoms at diagnosis, though they could have any of the symptoms that people with type 1 experience. (La Crosse Tribune, WI)
Kate's Kats raising money for juvenile diabetes cure Feb 21, 2007
Katie's diabetes was detected early, before she went into ketoacidosis, which can be life-threatening to a diabetic. he was diagnosed early during her honeymoon period,' Farrier said. (Winter Garden West Orange Times, FL)
Prisoner lacked insulin Feb 8, 2007
The official cause of death for Kevin McNabb, 51, an insulin-dependent diabetic who died in custody Oct. 13, is listed as diabetic ketoacidosis, according to the autopsy report filed by Dr. Steve Skoumal, a pathologist who performs autopsies for the Bannock County Coroner Office ... Dr. Fan Zhou, a pathologist for Portneuf Medical Center, said diabetic ketoacidosis is caused by a lack of insulin. (Pocatello Idaho State Journal, ID)
Examination of diabetes is political, and personal Jan 12, 2007
"Survival requires a balance of forces. If one becomes too strong (for example, if you overeat), then reinforcements are needed (you require more insulin). And if one army has retreated entirely (you skip several shots or meals), the remaining brigade of rampaging food or unchecked insulin unleashes its destructive force on the body itself, causing ketoacidosis or hypoglycemic coma. The battles never produce a winner. The armies simply live to fight another day.". Nondiabetics have written... (Boston Globe)
'Kid Suffered Beyond Belief' Jan 10, 2007
But the coroner's report said toxicology reports came back "negative for Pine-Sol constituents" and that the boy had suffered ketoacidosis -- a dangerous buildup of acids in the blood -- possibly as a result of starvation, Chang said. Contra Costa County child-welfare workers investigated allegations of abuse or neglect involving Raijon Daniels on five occasions since 2002, according to a report issued by the county's Children and Family Services to state officials. (San Francisco Chronicle -- Crime)
