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    News and Articles on Laboratory Animals



    Bisphenol A may impair learning and memory  Sep 4, 2008
    Bisphenol A is mired in controversy because the manmade chemical is able to mimic the hormone estrogen in living things, and has been found in dozens of laboratory animal and test tube experiments to be biologically active at small doses. Although estrogen is most often viewed as the primary female sex hormone, it is also needed to ensure the proper development of synapses. (Globe and Mail -- Business)

    Scientist advocates unusual uses for trees  Aug 13, 2008
    The black walnut, for example, contains limonene, which is found in citrus fruit and elsewhere and has been shown to have anticancer effects in some studies of laboratory animals. Beresford-Kroeger has suggested, without evidence, that limonene inhaled in aerosol form by humans will help prevent cancer. (International Herald Tribune -- Health)

    Might science help stave off old age?  Aug 2, 2008
    It is so much easier to play with genes in laboratory animals such as mice, fruit flies or C. elegans, a worm that is the workhorse of aging research. Scientists have been able to dramatically increase the lifespans of all these creatures by altering single genes, often without an increased incidence of cancer. (Globe and Mail)

    Foods High In Conjugated Linoleic Acids Can Enrich Breast Milk  Jul 29, 2008
    ScienceDaily (July 28, 2008) Have a cookie before breast-feeding, mom. Eating special cookies enriched with conjugated linoleic acid (CLA) can increase the level of these potentially healthful fatty acids in breast milk, reports a recent study in the journal Nutrition Research. (Science Daily)

    Questions arise over CDC germ lab  Jun 22, 2008
    Goodwin, a veterinarian, is executive director of the Center for Laboratory Animal Medicine and Care at the University of Texas Health Science Center in Houston ... "It could be inconsequential or it could be consequential," said Chris Newcomer, executive director of the Association for Assessment and Accreditation of Laboratory Animal Care International, commenting in general and not about CDC's lab in particular. (Atlanta Journal-Constitution)

    Statins use may reduce caesarean births  Jun 18, 2008
    New trials are now underway in laboratory animals to test whether reducing cholesterol levels with drugs such as statins can improve contractions and if successful large scale human trials could begin within five years. Statins are already taken by around four million patients in the UK with heart disease and cost around four pence per patient per day. (Telegraph.co.uk)

    Treatment For Severe Blood Loss: Less Is More  May 14, 2008
    18, 2000) Scientists at the National Institute on Drug Abuse (NIDA) have demonstrated that laboratory animals will self-administer marijuana's psychoactive component, THC (delta-9-tetrahydrocannabinol), in. (Jul. (Science Daily)

    FDA soon may support biomarker tests  Apr 17, 2008
    He cites two recent examples of drugs in trouble, both of which showed toxicity in laboratory animals: the diabetes drug Avandia from GlaxoSmithKline and Vytorin from Schering-Plough and Merck, a cholesterol-lowering medication. "Avandia showed evidence of heart damage in animal studies and, for Vytorin, tests showed serious toxicity in laboratory animals, regardless of how low a dose of this combination drug was used," says Wolfe. (San Francisco Chronicle -- Technology)

    Think again: Exercise on the brain  Nov 9, 2007
    Environmental enrichment does improve mental function in laboratory animals. Rodents and monkeys that get playmates or toys learn to complete a variety of tasks more easily, at all ages. (International Herald Tribune)

    Marked Brain Changes Afflict Even Senior Citizens Who Have Escaped Alzheimer's Disease  Nov 8, 2007
    Prompted in part by laboratory animal studies suggesting that frequent physical activity encourages new brain cells to develop, many people have taken up jogging, walking, swimming, and other forms of regular exercise to improve and preserve their cognitive abilities as well as their cardiovascular health. However, few studies have been conducted to examine how a person's cognitive performance and its neurophysiological correlates are influenced by the individual's overall motor status. (Science Daily)

    Sleep, And How Cocaine Changes The Brain To Make Treatment So Difficult  Nov 8, 2007
    Previous laboratory animal studies have suggested that repeated cocaine self-administration increases the expression of excitatory neurotransmitter receptors in the accumbens ... However, when their self-administration was intermittently punished by a mild foot shock, most of the laboratory animals consumed less drug. (Science Daily)

    Scientist bites back at animal activist vandals  Nov 6, 2007
    She replied with a heartfelt letter to the L.A. Times, headlined Why I Use Laboratory Animals. I have devoted my career to understanding how nicotine, methamphetamine and other drugs can hijack brain chemistry and leave the affected individual at the mercy of his or her addiction. (The Palm Beach Post)

    Are Microchip Tags Safe?  Oct 25, 2007
    But VeriChip came under fire in September shortly after the first 90 or so Alzheimer's patients received its chips in Florida after an AP report unearthed studies suggesting the chips may cause cancer in laboratory animals. Within two weeks of the AP report, VeriChip's stock plummeted from just under $6 a share to a low of $3. (Time.com)

    A Step Toward Tissue-engineered Heart Structures For Children  Sep 21, 2007
    The researchers, led by Sales and senior investigator John Mayer, MD, in Children's Department of Cardiac Surgery, first isolated endothelial progenitor cells (precursors of the cells that line blood vessel walls) from the blood of laboratory animals. They then "seeded" the cells onto tiny, valve-shaped biodegradable molds and pre-coated with proteins found in the natural "matrix" that surrounds and supports cells. (Science Daily)

    UCSF Animal Care Facility Receives Top Accreditation UCSF, Sep. 10  Sep 11, 2007
    UCSF has received highly regarded accreditation from the Association for Assessment and Accreditation of Laboratory Animal Care International ... These include the U.S. Public Health Service Policy on Humane Care and Use of Laboratory Animals, the U.S. Department of Agriculture (USDA) National Research Council Guide for the Care and Use of Laboratory Animals, and the USDA Animal Welfare Act Regulations regarding the care and use of animals in a research setting. (University of California Newswire, CA)

    Scientists honoured for sparing animals the lab  Aug 22, 2007
    "No laboratory animals were used in this research." That is a claim to which an increasing number of medical scientists aspire, and one that has won a team of Sydney cancer specialists an Australian Museum Eureka Prize. Maria Kavallaris, Sela Pouha and Nicole Verrills have discovered why some leukaemia cells become resistant to drugs. (Sydney Morning Herald -- Australia)

    From lab to the limelight  Aug 16, 2007
    Raghib has developed a technique for doing this that does not require laboratory animals. Those who vote in the People's Choice Prize before midnight on Sunday will be in a draw to have part of their DNA sequenced and framed. (Sydney Morning Herald -- Australia)

    Scientists Engineer World's First Schizophrenic Mice  Jul 30, 2007
    It will allow researchers to study the disease and develop treatments using a limitless supply of laboratory animals. Animal rights campaigners have condemned the research, saying that it is morally repugnant to create an animal doomed to mental suffering. (Fox News)

    Consumer Group Endorses Study Showing How Diet Drinks Can Trigger Heart Attacks, Stroke and Diabetes  Jul 27, 2007
    Food and Drug Administration toxicologist, Dr. Jerome Bressler discovered unreported heart and other life threatening problems in the laboratory animals, showing how the original drug company tests could have been 'falsified' to gain approval for the sweetener. Public figures, with histories of serious heart problems, who are also reported to be daily consumers of diet sodas include: President Bill Clinton (Diet Coke),Vice President, Dick Cheney (caffeine-free Diet Sprite) and television... (Yahoo News -- Press Releases)

    Obesity caused by combination of stress and high fat diet - study  Jul 4, 2007
    Investigators at Georgetown University Medical Center have been able to use simple, nontoxic chemical injections to add and remove fat in targeted areas on the bodies of laboratory animals. (Credit: Georgetown University). (Food Consumer)

    Scientists Find Way to Block Weight Gain in Stressed...  Jul 3, 2007
    Scientists from have found that blocking the pathway that leads stressed people to gain weight is the key to manipulating fat at least in laboratory animals. The findings, published online in on Sunday, explain why people who are chronically stressed often develop "metabolic syndrome," a condition which causes individuals to gain more weight than they should based on the calories they consume. (Fox News)

    Scientists Discover Key To Manipulating Fat; Pathway Also Explains Stress-induced Weight Gain  Jul 3, 2007
    In what they call a "stunning research advance," investigators at Georgetown University Medical Center have been able to use simple, non-toxic chemical injections to add and remove fat in targeted areas on the bodies of laboratory animals ... Investigators at Georgetown University Medical Center have been able to use simple, nontoxic chemical injections to add and remove fat in targeted areas on the bodies of laboratory animals. (Science Daily)

    Use of Mice in Biomedical Research  Jun 27, 2007
    These developments are all reflected in the latest edition (7th ed.) of the Guide for the Care and Use of Laboratory Animals of the National Research Council (NRC) of the United States ... International Committee of the Institute for Laboratory Animal Research ... Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council. (Suite101.com)

    Group: Livestock may help treat ailments  May 16, 2007
    Bruce Friedrich, a vice president of People for the Ethical Treatment of Animals, or PETA, called the technology "Frankenstein science" that leads to the death of many laboratory animals. He said there can be terrifying consequences for humans if diseases cross species barriers. (Herald Online, SC -- Health)

    New Stem Cell Method Promises To Repair Severe Blood Vessel Damage  May 10, 2007
    In what has been described as a breakthrough, US scientists have found a new way to use human embryonic stem cells to produce precursor cells that can repair severely damaged blood vessels in mice and other laboratory animals. They hope this method will one day be used to repair extensive blood vessel damage in humans, for instance diabetics with damaged retinas, people with severe blood vessel damage in limbs (and thereby avoid amputation), and reducing deaths from heart attacks. (Medical News Today)

    Scientists Find Gene Linking Lifespan to Calorie Restriction  May 5, 2007
    " Dillin says that activating the pha-four gene is one of two major ways to lengthen life in laboratory animals. Another is to decrease their sensitivity to insulin, a hormone that regulates blood sugar. But this has unwelcome side effects, such as stunting and reproductive problems. It is a long evolutionary leap from earthworms to people, but Dillin says it is worth determining if the human versions of the pha-four gene operate the same way. The goal would be to develop a drug that could... (Voice of America)

    High Doses Of Phytochemicals, Including Flavanoids, In Teas And Supplements Could Be Unhealthy  May 2, 2007
    The data was from studies done in humans and laboratory animals. The report cites specific examples of toxic effects, including reports of liver, kidney, and intestinal toxicity related to consumption of high doses of green tea-based dietary supplements. (Science Daily)

    Pill to boost women's sex drive and help them lose weight  Apr 30, 2007
    However, in an unexpected short-term side-effect, the laboratory animals also ate significantly less food than usual. In some cases this was one-third less than their usual daily diet. (Scotsman)

    FDA advisers get behind new type of HIV drug  Apr 25, 2007
    The drugs also have been linked to heart rhythm changes in laboratory animals. FDA reviewers noted no increase in lymphomas or infections among patients given Celsentri, but said there was a modest increase in liver problems. (MSNBC -- Health)

    'Inherently toxic' chemical faces its future  Apr 7, 2007
    Some researchers with close-up views of bisphenol A are so shocked by its ability to skew development in their laboratory animals, even at among the lowest doses ever used in experiments, they aren't waiting for the government to ban it. In their personal lives, they can't run away from products containing it fast enough. (Globe and Mail)

    First Step In Developing Heart Hormone-based Pill To Control High Blood Pressure  Mar 28, 2007
    The researchers tested the oral BNP by inducing high blood pressure in laboratory animals, and then giving them the experimental drug ... In this way, the team designed a novel chimeric peptide and defined its heart-kidney action by testing it in laboratory animals. (Science Daily)

    Study Citing Antioxidant Vitamin Risks Based On Flawed Methodology, Experts Argue  Mar 2, 2007
    A study recently published on possible health risks of antioxidant supplements is based on flawed methodology and ignores the broad totality of evidence that comes to largely opposite conclusions, say experts from the Linus Pauling Institute at Oregon State University. The research, which was published in this week s edition of the Journal of the American Medical Association, concluded that antioxidant supplements such as vitamins A and E may significantly increase mortality, and that there was... (Science Daily)

    Drug being tested to see if it can control diabetes  Jan 30, 2007
    The drug has already proven to help laboratory animals and people in smaller studies control diabetes and blood pressure. It s not going to be a spectacular drug but it s cheap and it s generic and if we prove that it works it will help control this epidemic of diabetes and maybe even help heart disease, said Tulane Endocrinologist Dr. Vivian Fonseca. (WWLTV.com, LA)

    Folic Acid May Prevent Cleft Lip And Palate  Jan 27, 2007
    "Folic acid deficiency causes facial clefts in laboratory animals, so we had a good reason to focus on folic acid in our clefts study," said Wilcox. "It was one of our main hypotheses.". (Science Daily)

    Study claims to solve drug trial mystery  Jan 27, 2007
    Dr Federica Marelli-Berg, of the Department of Immunology at Imperial College London, presented the findings of research suggesting why the inexperienced immune systems of laboratory animals did not react to the drug ... However the same tests on laboratory animals did not provoke any immune system reaction. (Telegraph.co.uk)

    Dog sacrificed for sales demonstration  Jan 19, 2007
    An institution's policy for animal use is by the institution's IACUC, which is reviewed and approved by the USDA. General guidelines that must be followed are outlined in the federal (in which rats and mice are ) and the on Humane Care and Use of Laboratory Animals ... JK Borchardt, "US debates care standards for small laboratory animals," The Scientist, July16, 2001 ... Public Health Service Policy on Humane Care and Use of Laboratory Animals. (The Scientist)

    Amniotic stem cell find could overcome barriers to using embryos  Jan 8, 2007
    The study also suggests another advantage: unlike embryonic cells, which can form tumours when implanted in laboratory animals, amniotic fluid stem cells do not appear to do so. It is still unclear whether stem cells from amniotic fluid - the liquid that cushions babies in the womb - can give rise to the full range of cell types that embryonic stem cells can produce. (Sydney Morning Herald -- World)

    Immune System Cells Linked To Heart Failure  Dec 29, 2006
    (April 16, 1998) -- Researchers have demonstrated in laboratory animals that tumor necrosis factor alpha, a protein produced in the heart, can lead to congestive heart failure. The finding may pave the way for a. (Science Daily)

    Christmas Is Good For You  Dec 22, 2006
    In research first published in the ACS Journal of Agricultural and Food Chemistry in 2004, scientists at the U.S. Department of Agriculture found that several compounds from cinnamon significantly lower blood sugar levels in laboratory animals. The compounds appeared to mimic the action of insulin, and showed promising results at lowering blood sugar levels in humans with Type 2 diabetes. (Forbes)

    Where was the defense?  Dec 22, 2006
    Where was the defense. A fan's perspective on the Falcons. (Atlanta Journal-Constitution -- Sports)

    Experts 'to back monkey testing'  Dec 12, 2006
    BBC Science Correspondent Pallab Ghosh said research on primates caused particular controversy because they were more sentient than other laboratory animals and so suffered more. The committee, led by Oxford geneticist Professor Sir David Weatherall, heard evidence from 35 people, including representatives from academic organisations, animal welfare groups, the government and patients. (BBC News -- UK)

    Experts defend monkey research  Dec 12, 2006
    1% of the total number of laboratory animals. Some three-quarters of these are macaques, a genus that includes the rhesus monkey and the Barbary macaque, best known as the species found in Gibraltar. (Guardian Unlimited -- UK)

    Toward New Medications For Iron-overload Diseases  Nov 29, 2006
    The researchers report the synthesis and early testing in laboratory animals of a possible new generation of iron chelating drugs, compounds that remove excess iron from the body. In addition to working more efficiently than existing medications, the new compounds target specific organs such as the liver, heart and pancreas that are most vulnerable to iron-overload damage. (Science Daily)

    Cover: How We Worry  Nov 26, 2006
    To probe the risk-assessment mechanisms of the human mind, Joseph LeDoux, a professor of neuroscience at New York University and the author of The Emotional Brain, studies fear pathways in laboratory animals. He explains that the jumpiest part of the brain of mouse and man is the amygdala, a primitive, almond-shaped clump of tissue that sits just above the brainstem. (Time.com)

    Tβ4 is essential for coronary vessel development report  Nov 18, 2006
    In two articles published in the scientific journal, Nature, researchers found that TB4 protects heart tissue following a myocardial infarction (heart attack) and can regenerate coronary vessels in laboratory animals. Abstracts of scientific papers related to TB4's mechanisms of action may be viewed at RegeneRx's web page. (EurekAlert!)

    Why these foods help you prolong life  Nov 17, 2006
    By mimicking the effects of drastic calorie restriction which has been shown to prolong the lives of laboratory animals by up to one third resveratrol can do much the same. Leading the study, David Sinclair, at the Harvard Medical School, and Rafael de Cabo, at the National Institute on Aging, fed one group of mice a high-fat diet from the age of one year (their middle age), a second group was fed high-fat foods but with a large daily dose of resveratrol. (TimesOnline)

    Red wine substance appears to counter bad health in fat mice  Nov 2, 2006
    Previous research has shown that laboratory animals fed very low-calorie diets live significantly longer. In the hope of finding a drug that could harness the natural life-extending capabilities activated by caloric restriction, Sinclair and his colleagues identified a number of promising compounds, including resveratrol, which is found in red wine, grape skins and other plants. (FOX59, IN)

    Red Wine Compound Promotes Health, Study Finds  Nov 2, 2006
    Previous research has shown that laboratory animals fed very-low-calorie diets live significantly longer, which has prompted some people to try arduous "caloric restriction" diets as a possible fountain of youth, even though their effectiveness in humans remains unproven. In the hope of finding a drug that could harness the natural life-extending capabilities activated by caloric restriction, Sinclair and his colleagues identified a number of promising compounds, including resveratrol, which is... (Washington Post)

    Wine stops obesity's ills in mice  Nov 2, 2006
    Previous research has shown laboratory animals fed very low-calorie diets live significantly longer, which has prompted some people to try strenuous "caloric restriction" diets as a possible fountain of youth, even though its effectiveness remains unproven. To examine for the first time whether resveratrol could also extend longevity in mammals, Sinclair and his colleagues studied year-old mice, the equivalent of middle-aged humans. (Toronto Star -- World)

    Obesity drug may help Type 2 diabetes  Oct 30, 2006
    When the receptor is blocked in laboratory animals, they eat less and lose weight. Regulators in Europe licensed the drug as a weight-loss pill in June, in combination with diet and exercise, for people who are obese and at risk for diabetes. (CBC News)

    Passion over Covance runs high at session  Oct 28, 2006
    "25, 26 So, contrary to the propaganda put forward by the medical establishment to justify its work, animal experimentation does not save human lives. As the industry's own evidence proves, it does just the opposite. -------------------------------------------------------------------------------- Author's Note: This article is based on information contained in Sacred Cows and Golden Geese: The Human Cost of Animal Experimentation, by C. Ray Greek, MD, and Jean Swingle Greek (Continuum... (AZCentral -- Business)

    New Tool Can Help Predict Diabetes Complications  Oct 25, 2006
    Studies in laboratory animals revealed that caffeine stimulates the body's metabolism and may induce a mechanism that helps to reduce obesity, which is also strongly linked to type 2 diabetes. Other research suggests that a reduction in risk for diabetes may be due to compounds in coffee other than caffeine. (PR Newswire)

    Is it a bird, is it a plane, is it Superdave?  Oct 2, 2006
    In the past month alone he has met Nelson Mandela and repudiated Margaret Thatcher s ambivalence over the ANC two decades ago, laid a wreath at Gandhi s grave in India and, in another foreign trip, visited Scotland to lament that the poll tax was imposed there as if its people were mere laboratory animals. Further, in an underreported speech, he condemned the English caricature of Glaswegians as aggressive alcoholics. (TimesOnline)

    Possible Health Risks For Children Born To Overeating Mothers  Sep 23, 2006
    The ONPRC also participates in the voluntary accreditation program overseen by the Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC). Can't find it. (Science Daily)

    John Cassidy on neuroeconomics  Sep 15, 2006
    Unfortunately, this is an invasive procedure, and its experimental use has generally been restricted to laboratory animals. There is also a more fundamental objection to neuroeconomics and the Platonic view of decision-making. (New Yorker)

    Extremists target legitimate research  Aug 22, 2006
    The university's Animal Research Committee ensures that research strictly adheres not only to the federal Animal Welfare Act but also the "Guide for the Care and Use of Laboratory Animals" issued by the National Institutes of Health and guidelines issued by the National Research Council ... Laboratory animals are a critical component of modern research because they serve as effective models for the study of human disease ... Research involving laboratory animals has served as a vital cornerstone... (The Daily Bruin, CA)

    Parental Cigarette Use Is 'Double Whammy' For Children  Aug 11, 2006
    (October 18, 2000) -- Scientists at the National Institute on Drug Abuse (NIDA) have demonstrated that laboratory animals will self-administer marijuana's psychoactive component, THC (delta-9-tetrahydrocannabinol), in. . (Science Daily)

     City Honors Native Son With Special Day  Jul 6, 2006
    Crudup began a six-month training regimen learning more than 101 instruments of the surgical profession by performing exploratory surgery on laboratory animals. It wasn't much longer before medical students and surgical residents were watching Crudup's work when professors would send them over, saying, "go see Jimmy." Students from Japan, China, Canada and the United States were watching Crudup and then participating in their own surgical research under his supervision. (Forest Scott County Times, MS)

    Findings Reveal Possible Strategy Against Obesity, Diabetes And Infertility  Jul 6, 2006
    To learn whether STAT3 mediates some of leptin s activities, we devised a technique for inactivating STAT3 with pinpoint accuracy in the hypothalamus and observing the results in laboratory animals when we administered leptin, says Dr. Rossetti. Our tool for rapidly inactivating STAT3 was a cell-permeable peptide (short protein) that we infused into specific areas of the hypothalamus using fine needles. (Science Daily)

    Brain Research Breakthrough May Lead to Parkinson's Cure  Jun 23, 2006
    In experiments with laboratory animals, researchers were able to use this discovery to rescue the dying cells, repair the affected pathway, and improve neurological function, which could lead to better treatments for humans with Parkinson s disease. "For the first time we've been able to repair dopaminergic neurons, the specific cells that are damaged in Parkinson's disease," says researcher Susan Lindquist of Howard Hughes Medical Institute, in a news release. (Fox News)

    Good Hygeine May Be Cause of High Allergy Rates  Jun 20, 2006
    The study showed that wild rats and mice had higher levels of two types of antibodies normally associated with triggering allergies and autoimmune diseases in laboratory animals ... "While the production of these two antibody types lead to autoimmune disease and allergy, respectively, in the laboratory animals, their production seemed to represent a nonpathogenic, protective response to the environment by the wild rodents.". (Fox News)

    Microbes Transform 'Safest' PBDEs Into More Harmful Compounds  Jun 15, 2006
    In laboratory animals, high blood levels of PBDE are associated with cancer, lowered immunity, thyroid problems, and learning and memory difficulties. Although PBDE levels in people haven t reached the levels of laboratory animals, Alvarez-Cohen says scientists are concerned because they are rising in humans at an exponential rate, doubling every two to five years. (Science Daily)

    Soil-bound Prions That Cause CWD Remain Infectious  Apr 15, 2006
    To ascertain whether prions remain infectious in soil, the researchers also injected clay-bound prions into laboratory animals. The animals began to show TSE symptoms at approximately the same time as animals injected with only prions. (Science Daily)

    Studies Can't Prove Soy Formula Risks  Mar 18, 2006
    A variety of toxic effects, including stunted growth, sexual organ abnormalities, and decreased fertilization, have all been observed in laboratory animals ... Human infants consume much lower genistein doses than laboratory animals, and most of the chemical is not absorbed into the human bloodstream, says Karl Rozman, PhD, a University of Kansas toxicologist who led NIH panel. (Fox News)

    Blood Levels Of Suspected Carcinogen Vary By Race, Ethnicity  Mar 10, 2006
    Environmental Science ology. The study, by scientists at the Centers for Disease Control and Prevention (CDC) in Atlanta, is the first to detect racial or ethnic differences in levels of PFCs among humans. (Science Daily)

    Tysabri Waltzes through FDA Advisory Panel by 12-0 Vote  Mar 10, 2006
    Anita Smith was a human being and not a laboratory animal that belonged to Biogen. Thus, her records cannot be withheld at the companys direction. (Newsinferno.com)

    Soy Might Worsen Heart Condition  Jan 7, 2006
    As laboratory animals are routinely fed soy diets, and soy contains plant estrogens, the scientists took the mice off the soy and put them on milk-protein diets to better compensate for the differing male and female hormones. Their discovery of the significant improvement in the heart function of those male mice with HCM who had been switched to the milk-protein diet prompted them to change the focus of their work. (Forbes)


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