Key Allergy Gene Discovered Aug 26, 2008
nchen have pinpointed a major gene for allergic diseases. See also. (Science Daily)
Mayo Clinic on the Summer Olympic Games: Better Athletes, the Physiology of Performance, the Lactate Threshold, the Aging Athlete and Much More Aug 1, 2008
"As scientists search for genes and the determinants of performance, they keep drawing a blank. There have been no major gene discoveries saying that this gene really confers championship status or the potential for championship status of one person." Sports are complex behaviors for biologists, he says. Many genes contribute to performance, but it isn't likely that one individual would have the right combination of all genes that would give you a natural competitive edge, he says. (PR Newswire)
Story ideas for health reporters covering the summer Olympic Games Aug 1, 2008
"As scientists search for genes and the determinants of performance, they keep drawing a blank. There have been no major gene discoveries saying that this gene really confers championship status or the potential for championship status of one person.". Sports are complex behaviors for biologists, he says. (EurekAlert!)
Gladstone scientists create Wikipathways to foster research collaboration Jul 23, 2008
Building on the MediaWiki core that powers Wikipedia, they added a custom graphical pathway-editing tool and connections to major gene, protein and small molecule databases. This familiar web-based format makes it easy to participate. (EurekAlert! -- Business News)
SCRIPPS HOWARD NEWS SERVICE NEWS BUDGET Jul 20, 2008
OVULATIONGENE (Abraham, Toronto Globe and Mail) -- Scientists in Canada and France say they have discovered a major gene that governs ovulation -- a find that could yield new treatments for infertility and lead to a genetically based contraceptive. 600. (Scripps Howard News Wire)
Scientists isolate ovulation gene Jul 18, 2008
But scientists in Canada and France now say they have discovered a major gene that governs ovulation - a find that could yield new treatments for infertility and lead to a genetically based contraceptive. In a study released yesterday, researchers report that deleting a gene, known as Lrh1, in the ovaries of specially bred mice completely blocked ovulation. (Globe and Mail)
Evolution of fruit size in tomato Jun 28, 2008
Tanksley and his colleagues have been employing the data emerging from the International Tomato Genome Sequencing Project as well as the tools of structural genomics to clone and characterize the major gene and QTL responsible for extreme fruit size during tomato domesticationfas. The first QTL, fw2. (EurekAlert!)
Gene Craig Martin Jun 18, 2008
MONTROSE Retired Major Gene C. Martin passed away early Wednesday morning, June 11, 2008 at his residence in Montrose, Colo. Gene Craig Martin was born on July 27, 1919 in Seattle, Wash. (Montrose Daily Press, CO)
Mayo Clinic researchers find common gene disorder doubles risk of lung cancer, even among nonsmokers May 27, 2008
According to Dr. Yang, this study shows that the disorder "is among the highest for major gene effects on the risk of a common cancer.". A normal 1AT gene produces a protein that stops enzymes from breaking down elastin, which keeps lung tissue elastic for normal function. (EurekAlert!)
Click for Full Story Mar 16, 2008
In 1988, a federal grand jury indicted former National Security Adviser John M. Poindexter, fired White House aide Oliver L. North, retired Air Force Major General Richard V. Secord and Secord's business partner, Albert Hakim, on charges related to the Iran-Contra affair ... Sergeant Major Gene McKinney, once the Army's top enlisted man, was reprimanded and demoted one rank by a jury that had convicted him of obstruction of justice in a sexual misconduct case. (KWTX.com, TX)
Boron Is Essential For The Growth Of Plants And Animals Feb 29, 2008
4, 2007) Scientists have identified the major gene responsible for boron toxicity tolerance in barley, allowing breeders to select with 100% accuracy barley varieties that are tolerant to boron. Bot1 helps. (Science Daily)
Noah's Ark For Crop Seeds Opens In Arctic Norway Feb 27, 2008
Seeds deposited in the vault remain the property of the depositors, which include the world's major gene banks in developing countries. During a visit to the site on Monday, whirring freezer equipment added an extra chill to the first vault room to be opened. (Planet Ark, United States)
Locals prepare for Clinton visit Feb 23, 2008
There s not much we can do until we do, said Major Gene King with the Allen County Sheriff s Office. The Clintons aren t alone in their efforts to win Northwest Ohio. (Lima News, OH)
Characterization of paralogous protein families in rice Feb 20, 2008
High gene numbers in plant genomes reflect polyploidy and major gene duplication events. Oryza sativa, cultivated rice, is a diploid monocotyledonous species with a ~390 Mb genome that has undergone segmental duplication of a substantial portion of its genome. (BioMed Central)
Crucial Barley Gene Identified Dec 5, 2007
4, 2007) Adelaide scientists have identified the major gene responsible for boron toxicity tolerance in barley, allowing breeders to select with 100% accuracy barley varieties that are tolerant to boron. See also. (Science Daily)
Life-threatening Gene Defect Located: Mutation Linked To Thoracic Aortic Disease Nov 13, 2007
Milewicz said that mutations in ACTA2 account for 14 percent of the inherited form of thoracic aortic aneurysms and dissections, making it the major gene identified for this condition. "Dr. Milewicz has been an international leader in discovering gene defects that can cause vascular abnormalities," said study co-author Dong Kim, M.D., chairman of the medical school's Department of Neurosurgery and co-director of the Mischer Neuroscience Institute at Memorial Hermann. (Science Daily)
Life-threatening gene defect located by UT-Houston researchers Nov 12, 2007
Milewicz said that mutations in ACTA2 account for 14 percent of the inherited form of thoracic aortic aneurysms and dissections, making it the major gene identified for this condition. Dr. (EurekAlert!)
Research grant for eczema drugs Sep 27, 2007
Professor Irwin McLean, of Dundee University's College of Medicine, Dentistry and Nursing, said: "This is a really exciting opportunity to develop new treatments aimed directly at the first major gene known to be involved in eczema and related conditions.". One in five children in the UK and other developed countries suffer from eczema. (BBC News -- UK)
China to invest 20 bln yuan for eco-protection in Tibet Jul 16, 2007
Tibet is a region with the most typical biological diversity and is a major gene bank ensuring global biodiversity. However, the local ecosystem is very fragile and difficult to recover after being damaged. (Xinhuanet, China)
Largest Ever Study Of Genetics Of Common Diseases Published Jun 8, 2007
"Research from the Consortium has already played a major part in identifying the clearest genetic link yet to obesity and three new genes linked to type 2 diabetes, published in April in advance of the main study. It has found independently a major gene region on chromosome 9 identified by independent studies on coronary heart disease.Researchers analysed DNA samples taken from people in the UK -- 2,000 patients for each disease and 3,000 control samples -- to identify common genetic variations... (Science Daily)
The DNA of dogs Apr 6, 2007
"The study is a major milestone in canine genetics. We have precisely located the major gene that produces our miniature breeds," said study co-author Paul Jones, a genetics researcher at Mars Inc, the US confectionery and pet food giant which supplied DNA samples used in the study. All told, an international team of researchers examined the DNA of more than 3000 dogs from 143 breeds ranging from pocket-sized pooches such as the Chihuahua, Maltese, Pomeranian, pug and Pekinese to the huge Great... (iAfrica.com)
Major Gene Study Uncovers Secrets Of Leukemia Mar 9, 2007
Investigators at St. Jude Children's Research Hospital have discovered previously unsuspected mutations that contribute to the formation of pediatric acute lymphoblastic leukemia (ALL), the most common cancer in children. The discovery not only suggests novel methods for treating pediatric ALL, but also provides a roadmap for the identification of unsuspected mutations in adult cancers. (Science Daily)
Major Gene Study Points to Causes of Autism Feb 19, 2007
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New Alzheimer's Gene Discovered Jan 15, 2007
The first major gene for late-onset Alzheimer's, APOE, was discovered 14 years ago. Other genes have been linked to the early-onset form of the disease, which strikes before age 60 and accounts for only 10% of all cases. (BusinessWeek)
Researchers discover gene contributing to Alzheimer's Jan 15, 2007
The new discovery, to be published in the journal Nature Genetics, marks the second major gene linked to late onset Alzheimer's, the most common form of the disease. The first, a gene mutation called apoliprotein E-4, or ApoE-4, was pinpointed in 1993 and is estimated to increase a carrier's risk of Alzheimer's around age 60 by 2 times the average, Dr. St. George-Hyslop said. (Globe and Mail)
Researchers identify gene associated with severe kidney failure in diabetes Jan 10, 2007
"This is a major gene that appears to be associated with development of severe diabetic kidney disease," he said. The research team evaluated 858 subjects, including diabetic patients with end-stage kidney failure on dialysis, diabetic patients with normal kidney function, and healthy non-diabetic individuals. (EurekAlert!)
Drug breakthrough for ovarian cancer Dec 3, 2006
Professor Hani Gabra and his team at the Hammersmith Hospital in west London have discovered four major gene pathways that could reverse the resistance. This opens up the prospect of developing a drug to block these pathways and allow the chemotherapy to carry on working. (Guardian Unlimited -- UK)
Breakthrough in genetics sows better wheat seed Nov 26, 2006
" Sixty years later, plant scientist Moshe Feldman at the Weizmann Institute in Israel collected the same wild wheat from the hearths of Stone Age villages along the nation's northern coast and sent them to America. Then, in 1997 in his UC lab at Davis, geneticist and wheat breeder Jorge Dubcovsky assembled a team that began basic research into the genetic qualities of both wild and domesticated wheat strains. They cloned the ancient gene and showed in the lab that it could potentially speed the... (San Francisco Chronicle)
Blood test could preserve eyesight Nov 7, 2006
"We conducted the study because of the knowledge we had of the major gene contributing to AMD," Zhang said. "There were many studies which pointed to it, but the lab discovered the actual gene, which is a major contributor.". (Daily Utah Chronicle, UT)
Mutation in gene may play role in Crohn's Oct 28, 2006
In 2001, scientists identified the first major gene underlying Crohn's disease. Called Nod2, the gene regulates the immune system's response to bacteria in the gut. (Baltimore Sun)
Studies Link Gene Variant to Macular Degeneration Oct 21, 2006
Zhang added: "There is no question in my mind that this is a major gene for macular degeneration. The work from now on is to look at why this gene is responsible for macular degeneration. We can also go on to real drugs for AMD.". HealthDay. (MEDLINEplus)
New Gene Linked To Macular Degeneration Risk Oct 20, 2006
Dr. Zhang explains the significance of the discovery: "Several previous studies have implicated a major gene at chromosome 10q26 that affects the risk of AMD, but until this study the precise gene has not been identified.". AMD is a degenerative disorder affecting a portion of the retina called the macula. (Science Daily)
New Findings Back Eczema Gene Link Sep 27, 2006
In March this year, a group lead by Irwin McLean discovered a major gene (filaggrin) that causes atopic dermatitis (commonly known as eczema), the most common skin disease in the developed world. "It is tremendously gratifying that our discovery is being upheld by so many other groups around the world. This firmly establishes that a skin barrier defect underlies eczema and related conditions and importantly, sets the scene for the development of new and more effective treatments," said Professor... (Science Daily)
Variation In 3 Genes Influences Risk Of Age-related Macular Degeneration Sep 8, 2006
(April 4, 2005) -- Investigators at Vanderbilt University Medical Center and Duke University Medical Center have identified the first major gene that increases a person's risk of developing age-related macular ... (March 24, 2005) -- Researchers at Duke University Medical Center and Vanderbilt University Medical Center have pinpointed the first major gene that determines an individual's risk for developing age-related macular. (Science Daily)
Research to unleash gene therapy on arthritis Aug 14, 2006
The death of 18-year-old Jesse Gelsinger in 1999 was followed three years later by evidence that the first major gene therapy success -- treatment for a rare immune disorder known as ``bubble boy syndrome" -- caused cancer. Since then, there has been steady progress toward new treatments for immune disorders, cancers, and blindness, although there is still no gene therapy product on the market in the United States.``We're more sober and more careful," said Dr. Theodore Friedmann, president of... (Boston Globe -- Local)
Scientists Spot Psoriasis Gene Mar 24, 2006
While Elder and his colleagues have identified the PSORS1 gene -- which they believe is the major gene involved in psoriasis susceptibility -- they said that much more research is needed to identify other genes involved in the development of psoriasis. The findings appear in the May issue of the American Journal of Human Genetics. (MEDLINEplus)
Junk DNA may not be so junky after all Mar 24, 2006
In studying RET, the major gene implicated in Hirschsprung disease and multiple endocrine neoplasia (MEN2), the team identified DNA sequences that can control RET but had not been identified using standard methods. Hirschsprung disease, also known as congenital megacolon, is a relatively common birth defect marked by bowel obstruction. (EurekAlert!)
Eczema and asthma breakthrough Mar 21, 2006
Study leader Dr Irwin McLean said: "Finding this major gene for eczema and asthma allows us for the first time to understand what goes wrong in the skin of these patients and paves the way for development of new treatments or preventative measures.". The research was funded by medical research charity the Wellcome Trust and various skin disease charities. (Daily Mail - UK)
Breakthrough could revolutionise eczema, asthma treatment Mar 21, 2006
Queen's University graduates Dr Alan Irvine and Professor Irwin McLean have discovered the major gene that causes dry skin - leading to eczema and asthma. Recent statistics revealed that three people die of asthma in Northern Ireland every month. (Belfast Telegraph)
Hopes rise of cure for asthma and eczema after gene breakthrough Mar 21, 2006
"Finding this major gene for atopic dermatitis [eczema] and asthma allows us for the first time to understand what goes wrong in the skin of these patients and paves the way for development of treatments or preventive measures," he said. If too little or no filaggrin is produced, the skin is not an effective barrier, allowing moisture to escape from the body and foreign substances to get in. (Scotsman)
Segregation analysis of apolipoprotein A1 levels in families of adolescents: A community-based study in Taiwan Jan 20, 2006
Models containing major gene effect could be rejected ... These results suggest that variations of Apo A1 levels in the normal range, especially during adolescence, are likely to be influenced by multiple factors without significant contribution from major genes. (BioMed Central)
