Historic gene therapy trial to treat Alzheimer's disease underway at Georgetown Sep 23, 2009
The gene will instruct brain cells to produce more of a protein, called Nerve Growth Factor or NGF, which helps nerve cells survive and function properly. The transfer of this gene into the brain is a medical technique called gene therapy. (EurekAlert!)
Nutritional Supplement, SAMe, Effective In Preventing Formation Of Primary Liver Cancer In Rats Aug 3, 2009
19, 2007) Nerve growth factor (NGF), as the name says, is an essential peptide factor for the growth and differentiation of neuronal cells. Therefore we can imagine that this growth factor is important for the. (Science Daily)
Recognizing Obesity in Dogs & Cats ... Jul 27, 2009
NGF gene expression and secretion by canine adipocytes in primary culture: upregulation by the inflammatory mediators LPS and TNFalpha. V H Ryan et al. Hormone Metabolic Research. (Suite101.com)
Antidepressant Directly Stimulates Brain Growth Factor Receptors Jul 24, 2009
Keqiang Ye, PhD, associate professor of pathology and laboratory medicine at Emory University School of Medicine, and his colleagues were looking for chemicals that could imitate a protein in the brain known as NGF (nerve growth factor). NGF has been used experimentally to treat Alzheimer's disease and the degeneration of nerves in the extremities caused by diabetes ... However, NGF cannot cross the blood-brain barrier and has puzzled investigators with its side effects, such as increased... (Science Daily)
Investigating the development of mechanosensitivity May 23, 2009
In contrast, the competence to sense pain in the sensory neurons can only develop with the aid of nerve growth factor (NGF). It takes place at a later stage in embryonic development and even after birth. (EurekAlert!)
Golf firm tees off new business May 22, 2009
Last May, the (NGF) released a report titled The Future of Private Golf Clubs in America ... The NGF noted in that 2008 report that 10 percent to 15 percent of the nation s private golf clubs, some 500 or more, indicated that they were seriously challenged financially ... Those at-risk clubs, as defined by NGF in the 2008 report, stated that their membership and rounds of play were down an average of 29 percent and 22 percent, respectively. (San Antonio Business Journal, TX)
Bone Marrow Stem Cell Co-transplantation Prevents Embryonic Stem Cell Transplant-associated Tumors May 15, 2009
According to Dr. Yoshikawa, the transplanted BMSCs survived in the grafted site for at least five weeks after transplantation and maintained their ability to produce NGF.. "These findings are extremely important and emphasize the need for additional study on how embryonic stem cells may be used to treat human neurological problems in the not too distant future," commented Section Editor Dr. John Sladek, professor of pediatrics and neuroscience at the University of Colorado School of Medicine. (Science Daily)