Detox use helps teen addicts quit Nov 6, 2008
Suboxone, known generically as buprenorphine-naloxone, combines two drugs. Buprenorphine relieves withdrawal symptoms, while naloxone deters abuse by causing an opioid addict to experience rapid withdrawal symptoms if it is taken improperly, such as by injection. (India Times, India -- Health/Science)
Extended Therapy Helps Drug-Addicted Teens Nov 5, 2008
Both buprenorphine and naloxone have been shown to be effective in treating opioid addiction, but only limited use of these drugs has been recommended for younger patients. Buprenorphine works by relieving withdrawal symptoms and naloxone prevents or reverses the effects of injected opioids ... "If you keep these young kids, average one-and-a-half years of addiction, on buprenorphine-naloxone they did a lot better," said lead study author Dr. George Woody, a professor at the University of... (Washington Post)
Major study of opiate use in children's hospitals provides simple steps to alleviate harm Oct 6, 2008
If they found a clue such as a prescription for naloxone, a drug given to reverse the effects of opiates they read the chart more thoroughly for signs the patient was harmed. The researchers' efforts began paying off a few months after changes were instituted. (EurekAlert!)
Parent group arms others to reverse overdose Oct 3, 2008
Kinzly and several other states are advocates of dispensing Naloxone, commonly called "Narcan," an opiate antagonist that can immediately stop the overdose by neutralizing the effect of the drug. The drug is already used by first responders such as firefighters or paramedics, but is only available by prescription to others. (New Britain Herald, CT)
Codeine harmful to some breast-fed babies: study Aug 21, 2008
Strategies to prevent overdoses include taking minimal doses, not using the drug for more than four days, closely monitoring the baby for grogginess and, in suspected cases, providing the antidote naloxone. When a mother feels groggy, often the baby does as well. (Globe and Mail)
Actavis Totowa Announces Voluntary Recall at the Retail Level of All Drug Products Manufactured at its Little Falls, New Jersey Facility Aug 5, 2008
Pentazocine & Naloxone tablets. Cilostazol tablets 100mg. (U.S. Food and Drug Administration -- Alerts)
Bristol Officers Carry First-Aid Kits For Dogs Jul 28, 2008
Kenny is working with a veterinarian to equip Bristol's K-9 handlers with naloxone, a chemical that can act as an antidote. City police are trained as medical response technicians, and all of Bristol's front-line patrol cars carry emergency medical gear for humans. (FOX61, CT)
In a veterans' hospital, fighting a futile war Jul 16, 2008
Given naloxone, a drug used for narcotic overdose. I find something else troublesome. (International Herald Tribune -- Health)
Scripps, UCSD hospitals hit with fines for errors May 23, 2008
The state said pharmacists at the hospital were not adequately trained to dispense the right amounts of potentially dangerous medications such as naloxone, which is used to counter the effects of painkiller overdoses. Scripps Green was fined because equipment used in a patient's knee surgery in November was not sterilized and autoclave devices were not working. (San Diego Union-Tribune)
Heroin In Overdose Cases May Be Tainted May 21, 2008
He said the emergency room staff usually administers an antidote called naloxone to heroin overdose victims. But in the recent cases, the naloxone was not effective, bringing some of the victims out of comas only temporarily before they relapsed, he said. (FOX61, CT)
Autoimmune Eye Diseases Apr 8, 2008
In an earlier related animal study, Dr. Ian Zagon and his colleagues at Pennsylvania State University discovered that high doses of opiate antagonists such as naloxone and naltrexone increase cell growth and help repair corneal damage related to type 1 diabetes. In a recent study, which will be published in Archives of Ophathalmology, this same team of researchers has demonstrated that topical applications of high dose naltrexone in the diabetic eye prevents neovascularization, a major problem... (Suite101.com)
Hospital medicine mix-ups rising Apr 7, 2008
The use of the drug naloxone, an antidote for an overdose of morphine and related painkillers, was among the triggers. Symptoms include breathing difficulty and very low blood pressure. (Boston Globe)
Hospital mix-ups harm children Apr 7, 2008
Among triggers on the list is use of the drug naloxone, an antidote for an overdose of morphine and related painkillers; use of vitamin K, an antidote for an overdose of the blood thinner Coumadin; use of a blood test that detects insulin overdoses; and a lab test that identifies blood-clotting problems that can come from an overdose of the blood thinner heparin and other drugs. ABOUT THE STUDY: The researchers reviewed randomly selected medical charts for 960 children treated at 12 freestanding... (News & Observer)
Drug Warriors? Feb 26, 2008
For several years now, the drug naloxone has been used in emergency rooms and clinics to treat people who have overdosed on opium-derived drugs like heroin or morphine ... The naloxone story only reinforces in a tidier narrative what we've witnessed for the last 25 years that drug warriors are willing to write off the loss of human life as collateral damage and engage in all sorts of morally dubious practices in order to prove their point. (Fox News)
Fibromyalgia Treatment Feb 3, 2008
Subjects cannot have known allergies to naloxone or naltrexone. Contact Information. (Suite101.com)
Emergency antidote, direct to addicts Dec 12, 2007
"Because of our work he knew what to do. He dialed 911 and then injected the naloxone." ... Naloxone is a chemical that blocks the brain-cell receptors otherwise activated by heroin, acting in minutes to restore normal breathing ... Since its approval by the Food and Drug Administration in 1971, naloxone has become a standard treatment for overdoses, used almost exclusively by emergency medical workers. (International Herald Tribune -- Health)
Lifeline for addicts Nov 19, 2007
In Boston, addicts participating in the city's needle exchange program are trained to spray a prepackaged dose of Narcan, the brand name for naloxone, into the nose of the overdose victim. Nasal membranes absorb it even if the person has stopped breathing. (Boston Globe)
Heroin OD caused death Nov 12, 2007
An empty box of naloxone, a fast-acting overdose medication, and discarded syringe caps lay strewn outside Parent's apartment door as paramedics rushed into the apartment in an attempt to save his life. Described as a light-hearted joker by fellow Delta Upsilon fraternity members who knew him as "J-Rent," the Glastonbury, Conn. (Daily Collegian, PA)
Mass. to hand out heroin overdose kits Nov 3, 2007
The drug, known generically as naloxone, causes no long-term side effects, specialists said. A single dose costs about $20. (MSNBC -- Health)
Addicts to receive overdose antidote Nov 2, 2007
Narcan, known generically as naloxone, was developed as an antidote for overdoses. It is not habit-forming and causes no long-term side effects, although the sudden reversal of a heroin high can induce vomiting, specialists said. (Boston Globe)
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Painkiller Abuse Continues To Grow; New Treatments Offer Hope Jun 30, 2007
Doctors often prescribe a version of buprenorphine, combined with another opiate-blocker, naloxone, to guard against the intravenous use of buprenorphine. If the drug combination is injected, the naloxone can cause that person to quickly go into withdrawal. (Science Daily)
Suboxone Stepped Treatment Helps Heroin Addicts Jun 5, 2007
NEW YORK (Reuters Health) - For the treatment of heroin addiction, "stepped treatment" with Suboxone tablets, which contain a combination of buprenorphine and naloxone known to combat drug cravings, followed by escalation to methadone if needed, appears to work as well as methadone maintenance therapy, according to US and Swedish researchers. "The most important conclusion of the study," senior investigator Dr. Markus Heilig told Reuters Health, "is that it is safe and effective to offer all... (MEDLINEplus)
Options for treating drug addiction May 28, 2007
Suboxone: Subutex plus naloxone, an additive that prevents abuse of the drug by producing severe withdrawal if injected. Methadone: Synthetic opiate pills. (Sun-Sentinel.com)
UCSF launches study on treatment for prescription drug addiction Apr 19, 2007
The study will test the effectiveness of buprenorphine/naloxone combination tablets, marketed as Suboxone, along with different models of drug counseling in patients addicted to prescription opioids ... When combined with naloxone, buprenorphines abuse potential is further limited, as those who try to inject it to get high experience severe withdrawal symptoms, while no adverse effects occur when it is taken orally, as prescribed. (EurekAlert!)
Innovative pulmonary & PEGylation-based therapeutic product dev. drives business strategy of Nektar Apr 9, 2007
NKTR-118 combines Nektars Advanced PEGylation technology with naloxol, a derivative of the opioid-antagonist drug naloxone. A Phase 1 study indicates that NKTR-118 may have the potential to mitigate the constipation side effect from opioid use, without hampering the painkilling properties of opioid drugs in the central nervous system by reducing blood brain barrier penetration. (EurekAlert! -- Business News)
Heroin additive sowing death Jan 28, 2007
Rescuers responding to a heroin overdose all carry Narcan, an intravenous solution containing naloxone hydrochloride. It can immediately reverse the effects of a narcotic overdose and restore breathing and. (Cape Cod Times, MA)
Another gun in the arsenal Jan 15, 2007
Suboxone contains small amounts of a drug called naloxone. Naloxone is actually the antidote hospitals give to patients who have overdosed on methadone to keep them from dying ... With Suboxone, if someone crushes a pill and snorts or injects it, the naloxone gives them unpleasant withdrawal symptoms instead of a high. (Charleston Gazette, WV -- News)
Heroin deaths on the rise Jan 15, 2007
Health officials are considering expanding the use of the drug naloxone ... State officials are also exploring the possibilities of expanding the use of the drug naloxone, also known as Narcan, which works to reverse overdoses, he said. (Boston Globe -- Local)
