Got sleep? Red Sox, A's could use some Mar 29, 2008
Narcolepsy -- intermittent, uncontrollable episodes of daytime sleep -- is another disorder which is not only disruptive, it can be dangerous. Lack of sleep has also been linked to obesity and diabetes. (MLB.com -- Boston Red Sox)
Pharming and Generation Rx Mar 26, 2008
Stimulants, which are prescribed to treat the sleep disorder narcolepsy, attention-deficit hyperactivity disorder and obesity. Examples include dextroamphetamine (Dexedrine and Adderall) and methylphenidate (Ritalin). (Wood River Journal, ID)
High Prevalence Of Eating Disorders Found In Narcoleptics Mar 4, 2008
3, 2008) The majority of patients with narcolepsy/cataplexy experience a number of symptoms of eating disorders, with an irresistible craving for food and binge eating as the most prominent features, according to a new study ... The study, authored by Hal Droogleever Fortuyn, MD, and Sebastiaan Overeem, MD, of the Radboud University Nijmegen Medical Center in The Netherlands, focused on 60 patients with narcolepsy/cataplexy who were recruited from specialized sleep centers and 120 healthy... (Science Daily)
New study in the journal SLEEP finds a high prevalence of eating disorders in narcoleptics Mar 2, 2008
The majority of patients with narcolepsy/cataplexy experience a number of symptoms of eating disorders, with an irresistible craving for food and binge eating as the most prominent features, according to a study published in the March 1 issue of the journal SLEEP.. The study, authored by Hal Droogleever Fortuyn, MD, and Sebastiaan Overeem, MD, of the Radboud University Nijmegen Medical Center in The Netherlands, focused on 60 patients with narcolepsy/cataplexy who were recruited from specialized... (EurekAlert!)
Journal SLEEP: Methylphenidate can have sleep benefits in adults with ADHD Mar 2, 2008
MPH is a prescription stimulant commonly used to treat ADHD. It is also one of the primary drugs used to treat the daytime drowsiness symptoms of narcolepsy and chronic fatigue syndrome. A medication can provide much needed relief for someone with a severe sleep problem. (EurekAlert!)
Harvard doctor joins Rutherford County Sleep Center Mar 1, 2008
Sleep medicine specialists diagnose and treat sleep disorders like snoring and sleep apnea, narcolepsy, insomnia, and conditions such as sleepwalking, sleep talking and night terrors. Related Industry News. (Nashville Business Journal, TN)
JON LEIBOWITZ: How collusion keeps generic drugs off shelf Feb 28, 2008
The agency filed suit this month against Cephalon, which manufactures Provigil, a product that helps those with sleep apnea and narcolepsy. In 2003, four of Cephalon's competitors tried to enter the Provigil market -- which generated $800 million in sales last year -- by offering a low-cost generic version. (Fresno Bee -- Opinion)
Daytime Dozing May be Indicator of Future Stroke Feb 24, 2008
Sounds more like narcolepsy than dozing off ... Narcolepsy is falling into a deep sleep while dozing can be as short as seconds. (MedHeadlines)
New Sleep Diagnostic Center Opens at Methodist Mansfield Feb 22, 2008
The new center provides two specially designed sleep-study suites to evaluate sleep apnea, insomnia, restless leg syndrome, narcolepsy, snoring, sleepwalking, and other sleep difficulties ... His sleep training includes obstructive sleep apnea, central sleep apnea, restless leg syndrome, insomnia and narcolepsy. (PR Newswire)
Changes In Narcoleptics' Skin, Core Body Temperatures Affect Their Vigilance And Sleepiness Feb 6, 2008
Among those suffering from narcolepsy, however, direct manipulations of their skin and core body temperatures affect their vigilance and sleepiness, according to a new study ... The study, authored by Rolf Fronczek, of the Netherlands Institute for Neuroscience in Amsterdam, and Leiden University Medical Center in The Netherlands, focused on eight patients who were diagnosed with narcolepsy with cataplexy and suffered from excessive daytime sleepiness ... According to the results, patients were... (Science Daily)
Sleep disorders: Don't take it lying down Jan 29, 2008
Stimulants and antidepressants can treat narcolepsy daytime sleep attacks. Hypnotics like zopiclone or benzodiazepines can be prescribed for less than a fortnight to treat severe insomnia. (Independent)
Different Neural Pathways at Work Going under, Coming out of Anesthesia Jan 23, 2008
They found that mice with damaged orexin systems -- similar to humans with narcolepsy -- took much longer to awake from general anesthesia than mice with normal orexin signaling systems. However, the mice with faulty orexin systems did not fall asleep faster than normal mice when given a general anesthetic. (MEDLINEplus)
more » Jan 22, 2008
We deal with sleep apnea, narcolepsy, which requires daytime tests, restless leg syndrome and REM-related disorders. Sleep involving rapid eye movements REM is divided into three stages and is the most important part of sleep, Davis said. (Searcy Daily Citizen, AR)
Ship pilot's health scrutinized Jan 19, 2008
Modafinil, often sold under the brand name Provigil, is given to people with narcolepsy, sleep apnea, and other similar disorders to help them stay awake. Cota was also taking another prescription drug, apparently to treat anxiety, that person and a federal official said. (Boston Globe)
Rest covered from A to Zzz's Jan 18, 2008
Or it could be falling asleep suddenly during waking hours, called narcolepsy. And dysfunction in those activities could have links to heart disease, high blood pressure and metabolic disorders that could manifest themselves in diabetes and hypoglycemia, not to mention the traffic and industrial accidents resulting from poor concentration induced by poor sleep. (Daytona Beach News Journal)
2 different neural pathways regulate loss and regain of consciousness during general anesthesia Jan 12, 2008
Studying mice whose orexin systems had been genetically destroyed a state similar to humans suffering from narcolepsy, a neurological condition that causes unusual daytime sleepiness Max B. Kelz, MD, PhD, an assistant professor in Penns Department of Anesthesiology and Critical Care and the Mahoney Institute of Neurological Sciences, found that these mice took much longer to emerge from general anesthesia than those with normal orexin signaling systems. However, the mice with faulty orexin... (EurekAlert!)
Sleep Center aids the area’s restless Jan 8, 2008
Narcolepsy is an overwhelming, daytime sleepiness. The Sleep Center utilizes all-night sleep studies, monitoring physiological responses throughout the course of a rest period, even shift workers who sleep during the day. (Rolla Daily News, MO)
Protein Nasal Spray Revives Sleep-Deprived Monkeys Jan 8, 2008
A natural brain compound could help shift workers or those with narcolepsy, scientists say ... The researchers suggested that these results could have important implications for people suffering from the sleep disorder narcolepsy and for people whose lifestyles may cause sleep deprivation, such as shift workers. (MEDLINEplus)
Researchers Reverse Effects Of Sleep Deprivation Jan 4, 2008
"This could benefit patients suffering from narcolepsy and other serious sleep disorders. But it also has applicability to shift workers, the military and many other occupations where sleep is often limited, yet cognitive demand remains high.". Orexin-A, also known as hypocretin-1, is a naturally occurring peptide produced in the brain that regulates sleep. (Science Daily)
Baylor University Scientists Develop Cocaine Vaccine Jan 3, 2008
Researchers have developed a partly funded by DARPA. The medication is being looked at to help keep troops alert and will likely be used to treat the sleep disorder narcolepsy if it gets FDA approval. Comments. (DailyTech)
Nasal Spray Might Replace Sleep Dec 29, 2007
The discovery's first application will probably be in treatment of the severe sleep disorder narcolepsy. The treatment is "a totally new route for increasing arousal, and the new study shows it to be relatively benign," said Jerome Siegel, a professor of psychiatry at UCLA and a co-author of the paper. (ABC News)
From Shooting Pain To Shiver, Role Of Gatekeeper Protein In Sensing Cold Confirmed Dec 26, 2007
25, 2007) For the first time, neuroscientists have visualized cold fibers -- strands reaching from sensory neurons near the spinal cord to nerve endings in the skin tuned to sense different types of cold. Surprisingly, given the highly diversified sensory system and the range of sensations studied -- harmless cool, stinging cold, soothing coolness -- the fibers lead back to one place in the neuron: a protein known as TRPM8 that relays a cold signal up the spinal cord to the brain. (Science Daily)
News tips from the Journal of Neuroscience Dec 26, 2007
The loss of the hypothalamic neurons that produce orexin-A causes narcolepsy, and the administration of orexin-A produces arousal and increased attention. This week, Deadwyler et al. provide further evidence that orexin-A can counteract the effects of sleep deprivation. (EurekAlert!)
Vancouver anti-gang unit says tactics are working Dec 22, 2007
Body armour and tank-like SUVs seized in B.C. gang sweep. Body armour and tank-like SUVs seized in B.C. gang sweep. (CBC British Columbia)
1st Kuwaiti woman MP sworn in Dec 22, 2007
Health Canada has issued a warning about serious skin and allergic reactions related to Alertec, a drug used to relieve excessive sleepiness due to narcolepsy, obstructive sleep apnea and shift-work sleep disorders. U.S. health officials say improper use of patches that emit the painkiller fentanyl is still killing people. (Yahoo News -- Kuwait)
Apologies too little, too lame, too late Dec 20, 2007
We weren't spared the "it was the Jack Daniels ... flaxseed oil ... sex with my wife ... narcolepsy ... ginseng tea ... B-12 shot" part of the program. The routine looked a little different this time. (San Francisco Chronicle -- Sports)
Drugs to build up that mental muscle Dec 20, 2007
"There isn't any question about it -- they made me a much better player," said Paul Phillips, 35, who credited the attention deficit drug Adderall and the narcolepsy pill Provigil with helping him earn more than $2. 3 million as a poker player. (Los Angeles Times)
Sleepless in December Dec 15, 2007
MIAMI Between 50 million and 70 million Americans have some sort of sleep disorder, be it apnea, insomnia, narcolepsy ... suffers from narcolepsy, a disorder causing daytime sleepiness ... One in 2,000 suffer from narcolepsy, a neurological disorder causing people to fall asleep throughout the day, according to the National Sleep Foundation. (Herald Online, SC -- Health)
Sleep medicine 'can help ice addicts quit' Dec 2, 2007
He says Modafinil is normally used to treat sleeping problems like narcolepsy or shift work sleep disorder, and acts on the same parts of the brain as ice does. "Modafinil actually works in those parts of the brain to kind of restore areas of those neurotransmitters," he said. (ABC Online)
Practice parameters discuss treatment for narcolepsy, other hypersomnias of central origin Dec 2, 2007
Practice parameters published in the December 1 issue of the journal SLEEP serve as both an update of previous practice parameters for the therapy of narcolepsy and as the first practice parameters to address treatment of other hypersomnias of central origin, including idiopathic hypersomnia, recurrent hypersomnia and hypersomnia due to medical condition ... The following are highlights of recommendations for the treatment of narcolepsy and other hypersomnias of central origin ... Modafinil is... (EurekAlert!)
Hospital opens sleep disorder center Nov 30, 2007
The gathered data can then be used to diagnose different types of sleep disorders, including sleep apnea (the obstruction of the airway during sleep, causing loud snoring and sudden awakenings when breathing stops); narcolepsy (the condition of falling asleep spontaneously and unwillingly at inappropriate times); restless legs syndrome (an irresistible urge to move legs); REM behavior disorder (acting out violent or dramatic dreams while in REM sleep); and parasomnias (include a variety of... (Jakarta Post, Indonesia -- City)
Reasons women arent backing Hillary Nov 22, 2007
Reasons women arent backing Hillary - Melrose, MA - Melrose Free Press. Reasons women arent backing Hillary. (Melrose Free Press, MA)
Hormone links hunger, sleep Nov 17, 2007
Research conducted by UT Southwestern found that a lack of orexin is the cause of narcolepsy ... "If you can find a drug that substitutes for orexin, the strong prediction is that you can cure narcolepsy. Our results just emphasize this point." Page 1 of 1. (The Daily Texan, TX)
The BALCO investigation Nov 16, 2007
BALCO investigation timeline - USATODAY.com. Buy and sell tickets to premium and sold out events. (USA Today -- Sports)
Hormone Links Sleep, Hunger And Metabolism Nov 15, 2007
Researchers, including Dr. Masashi Yanagisawa, professor of molecular genetics at UT Southwestern, had found that lack of orexin causes the sleep disorder narcolepsy ... "You lack orexin" You've got narcolepsy. (Science Daily)
Cephalon settles drug marketing probe for $425M Nov 11, 2007
The probe was believed to be looking at whether company sales representatives were improperly marketing Cephalon's flagship drug Provigil, which is approved for narcolepsy and other sleep disorders, although physicians have prescribed the drug for other conditions, such as depression and attention deficit hyperactivity disorder. In February, the FDA sent Cephalon a warning letter ordering the company to discontinue promotional material for Provigil that included claims that the drug could be... (Philadelphia Business Journal, PA)
Cephalon settles marketing probe, raises earnings forecast Nov 10, 2007
Cephalon was being investigated for off-label sales and marketing practices of its drugs epilepsy drug Gabitril, narcolepsy drug Provigil and cancer pain reliever Actiq. Doctors can prescribe drugs for uses other than what s been approved by the U.S. Food and Drug Administration, but drug companies cannot promote such off-label marketing. (Somerset Daily American, PA)
Peek at the Week: The teams nobody can beat meet Nov 3, 2007
Welcome to the Narcolepsy Bowl. Atlanta is 30th in scoring; the 49ers are 31st. (CBS News)
The Prado gracefully revolutionizes its space Nov 1, 2007
Years of Spanish isolation, neglect under Franco, then institutional incompetence, compounded the impression of narcolepsy. Melancholy reports of leaks in the ceiling, or yet another director promising change before evaporating, overshadowed the odd loan exhibition. (International Herald Tribune -- Arts)
Britney and K-Fed battle it out again in court Oct 30, 2007
What about the narcolepsy situation. They found pills in her purse or pictures of pills, and now she has narcolepsy and she is driving ... BERNIE GRIMM, CRIMINAL DEFENSE ATTORNEY: She has narcolepsy and she is driving. (Fox News)
Provigil drug gets new warning on label Oct 26, 2007
Provigil is OK'd by the FDA as a treatment for narcolepsy and other disorders where excessive sleepiness is a symptom. As part of the new label, Cephalon (NASDAQ:CEPH) advised patients to stop using the drug and get medical attention if they develop a skin rash. (Philadelphia Business Journal, PA)
Remote Heat Imaging Identifies Sleep Disorder Without Disturbing Patients Oct 26, 2007
16, 2007) Modafinil is well-tolerated in the treatment of excessive sleepiness associated with disorders of sleep and wakefulness such as shift work sleep disorder, obstructive sleep apnea and narcolepsy, and. . (Science Daily)
From faithful dogs and difficult fish, insight into narcolepsy Oct 25, 2007
Bear had spent nearly seven years in the underground kennels as part of a colony of narcoleptic dogs studied by Dr. Emmanuel Mignot, director of the Stanford Center for Narcolepsy ... Bear's freedom ended 30 years of investigations that led to the discovery of the importance of a neurochemical called hypocretin in human and animal narcolepsy, and in normal sleep ... Investigators now understand that narcolepsy arises from a deficiency of the brain cells that make hypocretin, similar to the way... (International Herald Tribune -- Health)
FDA Warns on Cephalon's Provigil Oct 25, 2007
Provigil is indicated to improve wakefulness in adult with narcolepsy, obstructive sleep apnea/hypopnea syndrome and shift-work sleep disorder. The FDA warned that there have been rare cases of serious or life-threatening rashes, angiodema and multi-organ hypersensitivity reactions and also psychiatric side effects such as anxiety, mania, hallucinations and suicidal ideation. (TheStreet.com)
Is A Good Night's Sleep Crucial For Your Health? Oct 25, 2007
The group in Munich and Ingolstadt has first evidence for an influence of a chronic sleep disorder going along with severe sleepiness (narcolepsy) on the processing of emotional stimuli in the brain, suggesting that disturbed sleep regulation profoundly interferes with our well being and the interaction with the environment. Basic research in the human sleep research laboratory of the University of Z. (Science Daily)
Lack of sleep linked to emotional imbalance, imaging study suggests Oct 24, 2007
Sleep disorders include insomnia, sleep apnea, restless leg syndrome and narcolepsy. Parasomnias - including nightmares, night terrors and sleepwalking - also can disrupt sleep. (San Francisco Chronicle)
Modafinil Is Effective In Treating Excessive Sleepiness, Study Suggests Oct 17, 2007
A study published in the October 15 issue of the Journal of Clinical Sleep Medicine finds that modafinil is well-tolerated in the treatment of excessive sleepiness associated with disorders of sleep and wakefulness such as shift work sleep disorder, obstructive sleep apnea (OSA) and narcolepsy, and does not affect cardiovascular or sleep parameters ... In the narcolepsy studies one patient in the modafinil group and one in the placebo group had a clinically significant increase in heart rate ...... (Science Daily)
Fish Get Insomnia, Eyes Wide Open, Say Sleep Researchers Oct 17, 2007
The work represents a milestone in sleep research by Emmanuel Mignot, MD, PhD, who also uncovered the genetic cause of narcolepsy in dogs ... Mignot's laboratory found the gene responsible for narcolepsy in Dobermans and Labradors in 1999, helping reveal how the disorder occurs in humans ... Narcolepsy affects about one in 2,000 people, with few recognizing their sleepiness as a medical problem. (Science Daily)
Cycling: Franck Bouyer nears victory in bid to stay awake Oct 17, 2007
" Unless, that is, somebody is asleep at the switch. Often, that has been Bouyer. Today in Sports The 33-year-old Frenchman has narcolepsy, a disorder marked by recurring and unpredictable episodes of sleep during normal waking hours and disturbed sleep at night. He was diagnosed with the genetic disease, which is believed to afflict one person in 200,000, late in 2003 and since then his life has been, as he says without irony, a nightmare. It's not just that he tosses and turns while trying to... (International Herald Tribune -- Sports)
Size 0 teen battles body dysmorphic disorder Oct 7, 2007
Narcoleptic wrote on Oct 6, 2007 4:59 PM:" I just wish the Pantagraph could have done an article about me when I was seventeen. My teachers all thought I was lazy, my parents insisted I didn't go to bed at the correct time and my schoolmates had a blast doing things to me when I fell asleep in class. My own PCP even insisted I didn't show signs of narcolepsy. Whether or not this girl's condition is is considered "legitimate" by the medical community, I have a hard time believing that hers is a... (The Pantagraph newspaper)
Lower Metabolism, Eating Behavior Possibly Explain The Cause Of Overweight In Narcolepsy Oct 5, 2007
A lower metabolism, as well as slight changes in eating behavior, could explain the positive energy balance leading to being overweight in narcolepsy, according to a study published in the October 1 issue of the journal Sleep. The study, authored by Dorothe; Chabas, MD, PhD, of the F;d;ration des Pathologies du Sommeil, H pital Piti;-Salp tri;re, Paris, France, focused on 13 patients with narcolepsy and nine healthy controls matched for age, gender and ethnicity ... Only typical narcoleptic... (Science Daily)
Poison suspect charged again Sep 29, 2007
Detectives said it appeared Castor spiked the drink with Ambien, a prescription sedative used to treat insomnia, and Ritalin, a prescription stimulant used to treat attention deficit disorder (ADD) and narcolepsy. Prosecutor Christine Garvey said preliminary tests at the hospital revealed traces of opiates, codeine, morphine and hydrocodone in Ashley Wallace's system. (Auburn Citizen, NY)
Sleep-deprived Sep 26, 2007
Costa hopes to educate people about narcolepsy, sleep apnea and other sleep disorders as he travels from one competition to the next and through invitations to speak at conferences that deal with sleep disorders. Reading the shoreline, watching his boat's electronics, controlling the boat's movements with a foot pedal while pitching his line take constant concentration. (Albany Times Union)
FDA approves Cephalon's latest sleep-disorder drug Sep 21, 2007
The granted marketing approval to Nuvigil, 's next-generation product developed to treat excessive sleepiness associated with three medical conditions: sleep apnea, narcolepsy, and shift work sleep disorder. Nuvigil is an improved formulation of modafinil, the active pharmaceutical ingredient contained in Provigil -- the company's lead product. (Philadelphia Business Journal, PA)
Harris Methodist HEB to open sleep disorder lab Sep 16, 2007
in Bedford on March 17 will open its sleep disorder laboratory for the diagnosis and treatment of potentially serious sleep disorders, such as sleep apnea, excessive snoring, narcolepsy, restless leg syndrome and periodic limb movement disorder. The facility cost $12,000 and is expected to conduct 600 to 800 sleep studies annually. (Dallas Business Journal, TX)
Sentara offers quality care Sep 15, 2007
There are plenty of other sleeping disorders that affect people, such as narcolepsy, insomnia and restless leg syndrome, so having quality care for diagnoses and treatment nearby is important. Reader Comments. (Suffolk News Herald, VA)
Bucs' Boston Tests Positive For GHB, Lab Results Show Sep 11, 2007
" Expert Says It Was A Lot Of GHB Although the GHB in Boston's system does not seem like a significant amount, Cynthia Lewis-Younger, medical director for the Florida Poison Information Center in Tampa, said it is four times what one would expect to see in the urine of someone who received a prescribed, legitimate dose. The Food and Drug Administration has approved GHB as a treatment for narcolepsy, a sleep disorder. The forensic laboratory that tested Boston's urine does not test for GHB unless... (Tampa Bay Online, FL -- News)
Kamikaze pilots, Beats and Hells Angels all part of meth crisis history Sep 9, 2007
A pill form introduced five years later was used to treat narcolepsy, depression, obesity, epilepsy, schizophrenia, cerebral palsy and hypertension. The drug was even used to calm hyperactive children and cure hiccups, and one researcher catalogued 39 different clinical uses for it, journalist Frank Owen wrote in his book, "No Speed Limit.". (North County Times)
New lab to diagnose sleep disorders and offer solutions Sep 6, 2007
The company is expanding to Lansing later this month, where it will offer services to diagnose sleep disorders such as obstructive sleep apnea and narcolepsy ... There are currently 84 different sleep disorders that have been identified, including narcolepsy and catoplexy. (Leavenworth Times, KS)
New Data On Orexin Receptor Antagonist Almorexant Shows Therapeutic Potential to Restore Normal Physiological Sleep in Patients Suffering From Insomnia Sep 2, 2007
In all test settings, there have been no reports of cataplexy (sudden loss of muscle tone); a frequent symptom of narcolepsy syndrome associated with deficient orexinergic function. Also presented during the World Sleep Congress 2007 is further data from the almorexant entry-into-human study in 70 healthy male subjects assessing tolerability, safety, pharmacokinetics and pharmacodynamics(3,4). (Primezone Releases)
But your honour … I'm clean Aug 31, 2007
She claimed the drug had been prescribed for the treatment of the sleeping disorder narcolepsy, but later admitted that she did not suffer from the condition. - 1998, Dennis Mitchell 400m relay gold medalist and four-time US champion. (Sydney Morning Herald -- Sport)
It wasn't me who did it, coach Aug 31, 2007
reckoned that in 2003 she had narcolepsy, a condition which caused her to fall asleep, so she had to take drugs to stay awake. Months later she put up her hand, admitted to an extensive drugs regime and is now a strident anti-drugs campaigner. (Sydney Morning Herald -- Sport)
OUR OPINION: State board makes right call on Senate proposal Aug 27, 2007
Gcpecuvd wrote on Aug 25, 2007 9:46 PM:" Properties and by the cladribine areas have mild. Vaccines under tiviral compounds claforan weak and to state clarinex first. Distributive justice an older therefore highly removed. Some are to maintain clarithromycin preparing an claritin patients mean clemastine symptoms. The neuroscience may very womens average craving and clenbuterol successful. Peak viral insurance is income over cleocin nicotine is vaccines. Exposed to substances are fatality ratio... (Demopolis Times, AL)
Up to the tests Aug 20, 2007
Modafinil, used to treat narcolepsy, turned out to be a stimulant provided by BALCO mastermind Victor Conte. In second place in the 200 that year was Russia's Anastasiya Kapachinskaya; seven months later she tested positive for a steroid. (San Diego Union-Tribune -- Sports)
Two Wichita Clinic sleep labs earn accreditation Aug 8, 2007
The sleep laboratories perform overnight sleep tests for conditions such as sleep apnea, narcolepsy, restless legs syndrome and insomnia. They are two of four laboratories operated by the Sleep Medicine Center, which also has two Wichita locations. (Wichita Business Journal, KS)
