Early results from clinical trials of 2009 H1N1 influenza vaccines in healthy adults Sep 12, 2009
Contact: NIAID Office of Communications ... The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, also is conducting clinical trials of 2009 H1N1 influenza vaccines, produced by Sanofi Pasteur and CSL Limited ... The NIAID trials are testing two different dosages (15 micrograms versus 30 micrograms) and evaluating the immune response to one and two doses of these vaccines. (EurekAlert!)
H1N1 TRIALS: Pregnant women taking part Sep 11, 2009
"In everybody's list of who should be vaccinated, pregnant women are right at the top," says Anthony Fauci, director of the (NIAID), the study's sponsor ... The trial will be conducted through a NIAID-funded network of Vaccine and Treatment Evaluation Units at in Houston; Group Health Cooperative Center for Health Studies in Seattle; Saint Louis (Mo. (USA Today)
NIAID launches 2009 H1N1 influenza vaccine trial in pregnant women Sep 10, 2009
Contact: NIAID Office of Communications ... The first trial testing a candidate 2009 H1N1 influenza vaccine in pregnant women is launching this week, the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, announced today ... "Women are at higher risk of developing severe illness if they become infected with influenza virus while pregnant, which is why they are strongly encouraged to receive the seasonal influenza vaccine every year," says... (EurekAlert! -- Business News)
Here comes more government health care Aug 24, 2009
14 people met at CDC under the umbrella of NIAID NIH and some of them got so pissed off at pushing the older people to the back of the bus that they stormed out of the meeting without voting on ole Clifton Ave. ... So in other words, CDC, NIAID, and the ringmaster, Tony Fauci who is terrific at what he does don t know how virulent this wave will be and if older people truly have had some immunogenicity conferred on them by getting asymptomatic or mild cases of other flus during their lifetime. (Atlanta Journal-Constitution -- Opinion)
Veterans to routinely be offered HIV tests Aug 17, 2009
Micronics, Inc., today announced that it has been awarded a phase 2, two-year Small Business Innovation Research grant from the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) totaling approximately $770,000 to advance its rapid molecular diagnostic infectious disease platform for detection of mother-to-child transmission (MTCT) of the Human Immunodeficiency Virus 00003326 (HIV). The overall objective of the NIH grant is to determine... (Fresno Bee -- Local)
UN says 50 million women in Asia risk HIV Aug 12, 2009
This trial is being conducted by the HIV Vaccine Trials Network (HVTN), funded and supported by the National Institutes of Allergy and Infectious Diseases (NIAID). The HVTN is the largest worldwide clinical trials network. (Fresno Bee -- Nation)
NIAID scientists study past flu pandemics for clues to future course of 2009 H1N1 virus Aug 12, 2009
Contact: NIAID Office of Communications ... But two scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, say the existing data are insufficient to conclude decisively that the 1918-19 pandemic was presaged by a mild, so-called spring wave, or that the responsible virus had increased in lethality between the beginning and end of 1918 ... David Morens, M.D., Senior Advisor to the Director, NIAID, and Jeffery Taubenberger... (EurekAlert!)
Discovery To Aid In Future Treatments Of Third-world Parasites Jul 30, 2009
28, 2007) A new paper by NIAID scientist Thomas Nutman, M.D., and colleagues reviews network data collected between 1997 and 2004 to determine demographic and travel characteristics of travelers diagnosed with. (Sep. (Science Daily)
Halting A Pandemic: NIH Mounts Search For A H1N1 Vaccine Jul 25, 2009
ScienceDaily (July 24, 2009) Bracing for an outbreak of 2009 H1N1 (swine-origin) flu that a Saint Louis University infectious diseases expert estimates could sicken one in five people this fall, scientists at eight Vaccine and Treatment Evaluation Units funded by the National Institutes of Health (NIH) are launching a series of clinical trials this summer to test vaccines to protect against the illness. Efforts to find an effective vaccine against H1N1 influenza are historic, said Sharon Frey,... (Science Daily)
NIAID set to launch clinical trials to test 2009 H1N1 influenza vaccine candidates Jul 23, 2009
The research will be under the direction of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. "With the emergence of the 2009 H1N1 influenza virus, we have undertaken a collaborative and efficient process of vaccine development that is proceeding in stepwise fashion," says NIAID Director Anthony S. Fauci, M.D. ... "Now, NIAID will use our longstanding vaccine clinical trials infrastructurethe Vaccine and Treatment Evaluation Unitsto... (EurekAlert!)
South Africa: Researchers Launch HIV/Aids Vaccine Trials Jul 22, 2009
The trials are being conducted by Saavi, the HIV Vaccine Trials Network (HVTN) and the US National Institute of Allergy and Infectious Diseases (Niaid), which is part of the US National Institute of Health ... Dr Anthony Fauci, the head of the Niaid, which sponsored the trials, said South Africa was proving to be a useful ally in the quest for a vaccine. (allAfrica.com)
Scientists decode genome of deadly parasitic worm Jul 16, 2009
This work was supported primarily by grants from the National Institutes of Health (NIAID) and the Wellcome Trust. For further information, please contact Najib El-Sayed by e-mail at or by telephone at +1 (301) 405-2999. (EurekAlert!)
Flu Dynasty: Influenza Virus In 1918 And Today Jun 30, 2009
ScienceDaily (June 30, 2009) The influenza virus that wreaked worldwide havoc in 1918-1919 founded a viral dynasty that persists to this day, according to scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health ... "The 1918-1919 influenza pandemic was a defining event in the history of public health," says NIAID Director Dr. Fauci ... "The eight influenza genes can be thought of as players on a team: Certain combinations of... (Science Daily)
Yeast missing sex genes undergo unexpected sexual reproduction May 25, 2009
The Current Biology study was supported by National Institutes of Health/NIAID grants. Dr. Heitman's work in the Nature study was supported by grants from the NIH/National Institute of Allergy and Infectious Diseases (NIAID). (EurekAlert!)
Computer Simulation Captures Immune Response To Flu May 21, 2009
D., co-director of the CBIM. The work was funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and the U.S. Department of Energy. "High-speed, accurate computer simulation tools are urgently needed to dissect the relative importance of each attribute of viral strains in their ability to cause disease, and the contribution of each part of the immune system in a successful counterattack," said Zand. (Science Daily)
Chuck Panozzo, Founder of Rock Band Styx, Joins GeoVax Labs, Inc. as an Advocate for Its HIV/AIDS Vaccine May 21, 2009
Preclinical work enabling evaluation of GeoVax DNA and MVA vaccines was funded and supported by NIAID, which provided additional support to GeoVax AIDS vaccine development program with a $15 million IPCAVD grant awarded in late 2007. Safe Harbor Statement. (Yahoo! Wire -- Entertainment News)
Gene Transfer Technology May Lead To HIV Vaccine May 19, 2009
(Credit: Courtesy of Dr. Tom Folks, NIAID). Related Stories. (Science Daily)
Rocky Mountain Labs involved in swine flu study (28) May 17, 2009
In an e-mail, the NIAID declined to grant any interviews with its scientists at this time, citing a need to allow the scientists to focus on their study ... The e-mail response from NIAID echoed Feldmann's thoughts, saying information from (RML's) project will help scientists better understand how this newly emerging virus causes disease and may help to assess vaccines or antiviral therapies to prevent or treat the 2009 H1N1 virus. (Missoulian, MT)
Rational Design Of Vaccines: A Long But Essential Journey May 17, 2009
ScienceDaily (May 16, 2009) The holy grail of the defence mechanism against infectious diseases and tumours has not yet been discovered. In the search for a master switch in the immune apparatus of humans and animals, many strategies still need to be explored before the enormous potency of this complex system can be activated and controlled in the right manner. (Science Daily)
Mathematical Model Developed To Predict Immune Response To Influenza May 15, 2009
The project was conducted by investigators funded through the Modeling Immunity for Biodefense program, a program established in 2005 by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, to improve preparedness for emerging and re-emerging pathogens ... In addition to the investigators in Rochester, NIAID supports three additional laboratories across the United States as part of the Modeling Immunity for Biodefense program. (Science Daily)
RML adds swine flu study to its repertoire May 14, 2009
The National Institute of Allergy and Infectious Diseases (NIAID), in response to an inquiry on swine flu from the Ravalli Republic, confirmed that RML scientists have begun a study to develop an animal model of the virus infection in nonhuman primates ... The work at RML will proceed in conjunction with additional analysis by scientists at the CDC in Atlanta and elsewhere and should be submitted for publication in a scientific journal sometime this summer, NIAID officials said ... In an e-mail,... (Minnesota Farm Guide, MN)
Scientists develop mathematical model to predict the immune response to influenza May 14, 2009
NIAID media availability ... The project was conducted by investigators funded through the Modeling Immunity for Biodefense program, a program established in 2005 by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, to improve preparedness for emerging and re-emerging pathogens ... In addition to the investigators in Rochester, NIAID supports three additional laboratories across the United States as part of the Modeling Immunity for... (EurekAlert!)
SRI International to screen drugs that fight 2009 H1N1 influenza A May 14, 2009
May 13, 2009 SRI International, an independent, nonprofit research and development organization, announced today that that it will screen a library of well-characterized drugs against the 2009 H1N1 influenza A virus, previously known as "swine flu." The work will be performed under a resource contract from the Division of Microbiology and Infectious Diseases (DMID) in the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. There is currently... (EurekAlert! -- Business News)
Bacteria Play Role In Preventing Spread Of Malaria May 11, 2009
This research was supported by the Johns Hopkins Malaria Research Institute and the National Institute for Allergy and Infectious Diseases (NIAID), National Institutes of Health. Journal reference. (Science Daily)
Possible Link Between Childhood Obesity And Allergies May 9, 2009
The study was funded by the National Institute of Environmental Health Sciences (NIEHS) and the National Institute of Allergy and Infectious Diseases (NIAID), both parts of the National Institutes of Health. See also. (Science Daily)
InDevR's FluChip detects and distinguishes swine-origin H1N1 from human influenza viruses May 6, 2009
The FluChip was invented by a joint team of scientists at the University of Colorado at Boulder and the Centers for Disease Control and Prevention in an NIAID-supported effort led by then-Professor Kathy Rowlen, CEO of InDevR. InDevR recently licensed the intellectual property from the University of Colorado and CDC. ... "The FluChip assay detected all of the 6 swine-origin H1N1 viruses tested, and the resulting pattern, or signature, on the microarray was dramatically different than the... (EurekAlert! -- Business News)
Genetic study confirms the immune system's role in narcolepsy May 4, 2009
The study was funded principally by NINDS, with additional support from the National Institute of Mental Health (NIMH), the National Heart, Lung and Blood Institute (NHLBI), and the National Institute of Allergy and Infectious Diseases (NIAID), all components of NIH. ... NIAID () conducts and supports research to study the causes of infectious and immune-mediated diseases, and to develop better means of preventing, diagnosing and treating these illnesses. (EurekAlert!)
If Started Early, HIV Treatment Reduces Death Rates Toward Background Levels In African Countries May 3, 2009
This study was supported by the Office of AIDS Research (OAR) of the National Institutes of Health, the Agence Nationale de Recherches sur le SIDA et les Hepatites Virales (ANRS), and the National Institute of Allergy and Infectious Diseases (NIAID, grant 1 U01 AI069924-01). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. (Science Daily)
NIAID and Chinese officials sign agreement to foster TB research in China's Henan province Apr 29, 2009
Officials from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and from China's Henan Provincial Bureau of Health will meet in Zhengzhou, China, on April 29 to sign an implementation arrangement intended to foster research on tuberculosis, including clinical research on new treatments for multidrug-resistant tuberculosis (MDR TB). The Henan Provincial Bureau of Health and the NIAID plan to develop jointly a collaborative TB research... (EurekAlert! -- Business News)
US releases updated clinical guidelines for HIV-associated opportunistic infections Apr 17, 2009
News releases, fact sheets and other NIAID-related materials are available on the NIAID Web site at. . (EurekAlert! -- Business News)
OHSU scientists partner with others to form center aimed at combating infectious diseases Apr 16, 2009
7 million cooperative agreement from the National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health ... PNWRCE researchers will study a broad range of diseases and viruses, including Ebola, Dengue, SARS, avian and 1918 influenza, dengue fever, yellow fever, and West Nile, all of which are caused by pathogens that NIAID categorizes as A, B and C. NIAID priority pathogens in category A are the most dangerous and include Ebola and Dengue ... "We... (EurekAlert!)
Cure for extreme TB strain found Apr 8, 2009
According to scientists from Albert Einstein College of Medicine in New York and National Institute of Allergy and Infectious Diseases (NIAID), the drugs worked in tandem while one brought down the guard of the TB bacteria by inhibiting the enzyme that normally shields it from antibiotics, the other killed it. Phase II clinical trials on humans are now being planned simultaneously in South Korea and South Africa. (India Times, India)
Circumcision Guards Against STDs Mar 27, 2009
"We hope these data will ultimately result in policy changes in recommending circumcision for young boys or adult men to decrease the rates of infection with HIV, HPV and herpes," said the lead author of the Ugandan study, Dr. Thomas Quinn, a senior investigator in infectious diseases at the National Institute for Allergy and Infectious Diseases (NIAID) and a professor of medicine at Johns Hopkins School of Medicine in Baltimore. Results of Quinn's study appear in the March 26 issue of the New... (MEDLINEplus)
Statement From Sequella Founder and CEO, Dr. Carol Nacy at the 'Stop TB' Meeting in Brazil on the Eve of World TB Day Mar 24, 2009
Sequella recently received a $300,000 Small Business Innovation Research (SBIR) Phase I Grant from the National Institute of Allergy and Infectious Disease (NIAID), National Institutes of Health (NIH), to further fund the preclinical development this lead dipiperidine drug compound, SQ609. Sequella is currently undergoing pivotal Phase III TB Patch trials. (PR Newswire)
MRSA Study Suggests Strategy Shift Needed To Develop Effective Therapeutics Mar 23, 2009
This finding comes from a new study led by scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health ... NIAID scientist Michael Otto, Ph ... Earlier NIAID studies determined that alpha toxin and alpha-type PSMs play a crucial role in determining the severity of community-associated MRSA infection. (Science Daily)
Serious Infection In Pregnancy: Experimental Vaccine Shows Promise In Preventing Cytomegalovirus Infection In Infants Mar 21, 2009
The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), sponsored the trial ... Two additional NIAID-supported Phase II trials of the experimental CMV vaccine are under way ... The NIAID-sponsored trial will test whether the candidate CMV vaccine can boost the immune system enough to prevent illness from CMV.. (Science Daily)
Engineering Flu Vaccines: New Method Could Improve Vaccines For Both Seasonal Flu And Bird Flu Mar 19, 2009
(Credit: NIAID / Wikipedia). Related Stories. (Science Daily)
New Therapy Protects Lungs From Runaway Inflammation Mar 15, 2009
(May 3, 2005) Research performed at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has revealed that oxygen therapy aimed at helping mice with acute. (May 4, 2004) An enzyme that protects the body from reactive chemicals called free radicals is crucial in preventing the inflammation that causes chronic lung disease in premature infants, according to three new. (Science Daily)
Antibiotics combo may be cure for drug-resistant TB Mar 11, 2009
According to scientists from Albert Einstein College of Medicine in New York and National Institute of Allergy and Infectious Diseases (NIAID), the drugs worked in tandem while one brought down the guard of the TB bacteria by inhibiting the enzyme that normally shields it from antibiotics, the other killed it ... NIAID researcher Clifton Barry is launching a clinical study of the drug combination in South Korea by the end of 2009 involving approximately 100 TB patients. (India Times, India -- Community News)
Drug combination for resistant TB cure Feb 28, 2009
The significant increase in active TB cases since the 1980s is also due to the AIDS pandemic, said the researchers from the Albert Einstein College of Medicine of Yeshiva University and the National Institutes of Allergy and Infectious Diseases (NIAID). One of the drugs they studied, clavulanate, inhibits the bacterial enzyme beta-lactamase, which usually protects tuberculosis bacteria from the other antibiotic, meropenem, which comes from the beta-lactam class of antibiotics. (India Times, India)
Extensively Drug-resistant TB Defeated? Feb 27, 2009
In the Science paper, Einstein researchers and collaborators at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, describe a two-drug combination that inhibited both the growth of susceptible laboratory strains and 13 XDR-TB strains isolated from TB patients in laboratory culture medium ... D., Dan Danciger Professor of Biochemistry at Einstein and senior author of the Science paper, whose research was funded by NIAID. ... NIAID... (Science Daily)
Lab-made Proteins Neutralize Strains Of Flu Feb 23, 2009
A report describing the research, supported by the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health as well as the Centers for Disease Control and Prevention, appears online in Nature Structural & Molecular Biology ... "This is an elegant research finding that holds considerable promise for further development into a medical tool to treat and prevent seasonal as well as pandemic influenza," notes NIAID Director Anthony S. Fauci, M.D. "In the... (Science Daily)
Model Of Pre-exposure Prophylaxis Against HIV Forecasts Benefits, Potential Cost-effectiveness Feb 21, 2009
D., of Yale University, and supported by the National Institute of Allergy and Infectious Diseases (NIAID), the National Institute of Mental Health and the National Institute on Drug Abuse, all part of the National Institutes of Health. Dr. Paltiel says his team's model is the first to establish performance benchmarks that clarify the clinical, epidemiologic and economic circumstances under which PrEP would represent good patient care, good public health and good value. (Science Daily)
Anti-HIV Gel Shows Promise In Large-scale Study In Women Feb 14, 2009
Findings of the recently concluded study, funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the NIH, were presented Feb 9 at the Conference on Retroviruses and Opportunistic Infections in Montreal ... "Although more data are needed to conclusively determine whether PRO 2000 protects women from HIV infection, the results of this study are encouraging," says NIAID Director Anthony S. Fauci, M.D. ... HPTN 035 was conducted by the Microbicide Trials Network (MTN),... (Science Daily)
Scientists Identify Potential Key To Lyme Disease Feb 11, 2009
(June 21, 2001) A new test developed with funding from the National Institute of Allergy and Infectious Diseases (NIAID) has been shown to be highly accurate and sensitive for detecting antibodies to Lyme disease. . (Science Daily)
IL-2 immunotherapy fails to benefit HIV-infected individuals already taking antiretrovirals Feb 11, 2009
The Phase III trials, known as the ESPRIT and SILCAAT studies, were sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and funded respectively by NIAID and Chiron Corp. of Emeryville, Calif ... "In both studies, the volunteers who received IL-2 and antiretrovirals experienced notable, sustained increases in CD4+ T cell counts, as anticipated," notes NIAID Director Anthony S. Fauci, M.D. "Unfortunately, these increases did... (EurekAlert!)
Vaginal gel promising in AIDS prevention: study Feb 10, 2009
"Although more data are needed to conclusively determine whether PRO 2000 protects women from HIV infection, the results of this study are encouraging," said National Institute of Allergy and Infectious Diseases (NIAID) director Anthony Fauci in a statement ... NIAID is part of the NIH.. (Yahoo News -- Pharmaceutical Industry News)
Key factor discovered in controlling bone breakdown Feb 8, 2009
The study comes from the laboratory of immunologist Ronald Germain at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health ... "Most current therapies for bone-degrading diseases target mature osteoclasts," says NIAID Director Anthony S. Fauci ... Once at NIAID, Dr. Ishii worked with Dr. Germain's group to determine if S1P controlled immature osteoclast migration in live mice. (Xinhuanet, China)
Scientists discover key factor in controlling the breakdown of bone Feb 8, 2009
D., at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health ... "Most current therapies for bone-degrading diseases target mature osteoclasts," says NIAID Director Anthony S. Fauci, M.D. "Understanding how immature osteoclasts are recruited to the bone in the first place and targeting the signals that control that migration represents a potential new approach to treating and preventing debilitating joint and bone diseases." In the United... (EurekAlert!)
US blacks continue to bear the brunt of HIV/AIDS Feb 7, 2009
"NIAID-funded investigators are working to develop and validate new methods to protect against HIV infection.". NIAID also is conducting HIV/AIDS research specifically designed to benefit African Americans ... To locate NIAID-sponsored HIV/AIDS clinical trials that are seeking volunteers, go to ClinicalTrials. (Reuters)
