Findings Point To Molecular 'Achilles Heel' For Half Of Breast Cancer Tumors Jan 17, 2008
D. from NIDDK, NIH, decided to take a genetics approach to the problem. They created an animal model that both over-expressed ER and lacked cyclin D1. (Science Daily)
New genetic variants associated with lipid levels, risk for coronary artery disease Jan 14, 2008
SardiNIA is funded by NIA and FUSION receives support from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and NHGRI. Additional genetic data were provided by DGI, which involves Finnish and Swedish individuals and is a collaboration of the Broad Institute of Harvard and MIT, Cambridge, Mass ... Data used in this analysis were generated by studies supported by NIA, NHGRI, NIDDK and the National Heart, Lung and Blood Institute (NHLBI), all part of NIH; the Wellcome... (EurekAlert!)
Researchers uncover new piece to the puzzle of human height Jan 14, 2008
The Finns were participants in the Finland-United States Investigation of Non-Insulin Dependent Diabetes Mellitus Genetics (FUSION) study, which receives support from NHGRI and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) ... NIDDK Director Griffin P. Rodgers, M.D., said, This study is an example of how an investment in studies originally designed to evaluate specific diseases, such as diabetes, can lead to diverse and unexpected findings ... The research... (EurekAlert!)
Brain Response Differences In The Way Women With IBS Anticipate And React To Pain Jan 13, 2008
The study was funded by the National Institutes of Health (NIDDK and NCCAM) and in part by Novartis Pharmaceuticals. Dr. Mayer has received research grants from Novartis and has previously served as a consultant. (Science Daily)
Best bets on the Net Jan 3, 2008
Web Watch is compiled each day by Rich Ray, Online Managing Editor/Content. Last modified 12/31/2007 - 5:34 pm Originally created 010308. (Florida Times-Union)
Childhood Diabetes Boosts Risk for Kidney Problems Dec 29, 2007
"Since the development of diabetic kidney disease is strongly dependent on the duration of diabetes, developing diabetes in youth leads to a high risk of kidney disease in early- to mid-adulthood," said study author Dr. Robert G. Nelson, a staff clinician with the U.S. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) ... Native Americans, blacks and Hispanics have higher rates of kidney failure from diabetes, the NIDDK said. (Health-Finder)
ASH Honors Two Congressmen and NIDDK Director for their Public Service and Leadership in Hematology Dec 6, 2007
He is also the first hematologist to be named Director of the National Institute of Diabetes and Digestive and Kidney Disease (NIDDK). "It is an honor to recognize these individuals for their strong dedication to improving the understanding and treatment of blood disorders," said ASH President Andrew I. Schafer, MD, of New York Presbyterian-Weill Cornell Medical Center. (PR Newswire)
Depression Linked To Bone-thinning In Premenopausal Women Nov 28, 2007
The report was submitted by Giovanni Cizza, MD, PhD, MHSc, of NIMH and the NIH National Institute of Digestive Disorders and Kidney Diseases (NIDDK); Farideh Eskandari, MD, MHSc, of NIMH; and colleagues. Other NIH contributors to the study, in addition to NIMH and NIDDK, included the NIH Clinical Center and the National Center for Complementary and Alternative Medicine. (Science Daily)
Imaging Neural Progenitor Cells In The Living Human Brain Nov 17, 2007
The study was also funded by the NIH's National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). "This is the first noninvasive approach to identify neural progenitor cells in the human brain," says Grigori Enikolopov, Ph. (Science Daily)
Chronic Kidney Disease Common In The United States Nov 10, 2007
29, 2004) Ten to 20 million people in the United States have kidney disease but most don't know it, according to researchers at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). (May 13, 2006) Obesity is an important and potentially preventable risk factor for chronic renal failure (CRF), according to a study in the June Journal of the American Society of. (Science Daily)
Immune Cell Age Plays Role In Retinal Damage In Age-related Macular Degeneration Nov 8, 2007
This research was funded by grants from the National Eye Institute (NEI) and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health, a Carl Marshall Reeves and Mildred Almen Reeves Foundation Inc. Award, a Research to Prevent Blindness Career Development Award and an American Federation for Aging Research Grant. Adapted from materials provided by. (Science Daily)
Hepatitis C Treatment Reduces The Virus But Serious Liver Problems May Progress Nov 7, 2007
"The HALT-C trial unequivocally demonstrated that maintenance therapy with peginterferon does not prevent progression of liver disease among patients who have failed prior treatments," said James Everhart, M.D., project scientist for HALT-C and a program director for the Division of Digestive Diseases and Nutrition, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the principal sponsor of HALT-C at NIH. "These results add to the incentive to develop more effective drugs... (Science Daily)
Year End Report for Diamyd Medical AB, Fiscal Year 2006/2007 Oct 26, 2007
In September 2007, NIDDK/TrialNet announced plans for a clinical study involving Diamyd in 126 type 1 diabetes patients ... This together with strong interest from US diabetes trial organizations such as NIDDK/TrialNet has recently reinforced the interest in Diamyd ... In September 2007, Diamyd Medical reported that the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) has announced a planned international clinical study with the Diamyd diabetes vaccine in 126 new onset... (BusinessWire)
U.Va. embarks ondiabetes research Oct 16, 2007
In order to research different environments, researchers took data samples from children around the world, NIDDK Program Director Beena Akolkar said ... Illumina is an important addition to the University-NIDDK team because it provides the facilities and manpower to process all the information, Bornstein said. (The Cavalier Daily, VA)
Kids' Use of Heartburn Drugs Surges Oct 5, 2007
The Sentinel Online : Health. Friday, October 05, 2007. (Carlisle Sentinel, PA)
Kids' use of heartburn drugs surges; obesity, overuse a cause? Oct 4, 2007
TODAY'S HEADLINES SPECIAL SECTION ONLINE POLL. How far do you think the Cubs will make it into the playoffs. (Mattoon Journal-Gazette, IL)
Obesity and diabetes: It's where you deposit the extra fat that hurts Sep 23, 2007
In April, an international team of researchers, primarily sponsored by NIDDK, announced in the journal Science that after combing the human genome, they had identified at least four new gene variants associated with elevated diabetes risk and confirmed the existence of another six. More work must be done to figure out what the key genes actually do to influence diabetes development. (Pittsburgh Post-Gazette, PA)
Diamyd Medical: US National Institutes of Health Announces Plans to Sponsor a Type 1 Diabetes Trial with the Experimental Diamyd(R) Diabetes Vaccine Sep 21, 2007
Diamyd Medical (STO:DMYDY) announced today that the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) has posted a planned international clinical study with the Diamyd GAD-alum diabetes vaccine in 126 new onset type 1 diabetes patients on the NIH clinical trials webpage. The study is proposed by the NIH/NIDDK sponsored global network TrialNet, a group of the world s foremost experts and key opinion leaders in type 1 diabetes ... While the clinical protocol is not... (BusinessWire)
Brain-gut Relationship In Those Suffering With Stomach Pain Or Discomfort To Be Studied Sep 7, 2007
D., M.P.H., project scientist for FDTT and director of the Clinical Trials Program of the Division of Digestive Diseases and Nutrition, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the sponsor of the FDTT at NIH. "We are interested in learning more about the brain-gut interaction and physiological effects of these two similar but different classes of drugs on the symptoms associated with functional dyspepsia.". Currently, the treatment of functional dyspepsia is... (Science Daily)
Constipation's Many Causes and Cures Sep 4, 2007
People become constipated when the colon absorbs too much water or if muscle contractions in the colon become too slow or sluggish, according to the U.S. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) ... And, the NIDDK noted, certain neurological disorders, such as Parkinson's disease; metabolic and endocrine conditions, including diabetes; and systemic disorders, such as Lupus, also can cause problems by slowing the movement of stool through the colon, rectum or anus.... (MEDLINEplus)
Novel Cause Of Iron Overload In Thalassemia Disorders Discovered Sep 1, 2007
"The treatment of iron overload in patients with thalassemia is particularly difficult because of their anemia," says Jeffery L. Miller, M.D., chief of the Molecular Genomics and Therapeutics Section of the Molecular Medicine Branch, Division of Intramural Research, NIDDK, and last author of the study ... "Since erythroblasts need iron to make hemoglobin, we reasoned that the increased number of erythroblasts in thalassemia may send stronger messages to the liver to suppress hepcidin and thereby... (Science Daily)
Scientist Discovers Novel Iron-copper Alliance Jul 30, 2007
38 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The work will be carried out using established models of intestinal iron absorption in humans, including iron and iron/copper-deficient rodents and cultured intestinal epithelial cells. (Science Daily)
Mathematical Model Identifies Genes Which Battle Hepatitis C Jul 20, 2007
The team conducted clinical trials, supported by the Health National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the US National Institutes of Health (NIH), which included 400 patients at eight different centers in the United States. The hepatitis C virus, found mostly among many patients who have had a blood transfusion or who share needles, attacks the liver and in extreme cases can cause cancer of the liver. (Science Daily)
Older, cheaper diabetes drugs as safe and as good as Avandia and other newer pills, study says Jul 18, 2007
Wednesday 18 July, 2007. The clear winner: metformin, sold as Glucophage and generically for about $100 a year. (NEPA News, PA)
How Dietary Iron Is Used By Cells Jul 4, 2007
16 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Daniel Kosman, Ph. (Science Daily)
Sling Surgery Is More Effective Than Burch For Bladder Control In Women May 23, 2007
D., M.D., director of urology research at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) ... D., co-director of kidney and urology trials at NIDDK. ... NIDDK's Urologic Diseases in America project reports that up to three-fourths of women have some degree of incontinence, and the direct cost of incontinence for women was 12. (Science Daily)
Diabetes Pill Tied to Heart Risks May 22, 2007
The Sentinel Online : Health. Tuesday, May 22, 2007. (Carlisle Sentinel, PA)
New Genetic Risk Factors For Type 2 Diabetes Identified Apr 29, 2007
D. of the University of Helsinki and National Public Health Institute in Finland; the U.S.-Finnish team received major support from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and NHGRI's Division of Intramural Research, both part of the NIH. The laboratory analysis of genetic variants in the first stage of the study was conducted by the Center for Inherited Disease Research, using funding from NIH and The Johns Hopkins University in Baltimore ... NIDDK Director... (Science Daily)
U of M-led study identifies new genetic risk factors for type 2 diabetes Apr 27, 2007
The FUSION team received major support from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and NHGRI's Division of Intramural Research, both part of the NIH.. For more information on Boehnke, visit. (EurekAlert!)
Uncle Sam wants you ... to start getting fit Apr 24, 2007
- Serving York, Chester, and Lancaster Counties. Tuesday, April 24, 2007. (Herald Online, SC -- Health)
NIH Launches Study To Assess Bariatric Surgery In Adolescents Apr 21, 2007
They will still need to eat less food and exercise more, says Mary Horlick, M.D., project scientist for Teen-LABS and director of the Pediatric Clinical Obesity Program of the Division of Digestive Diseases and Nutrition, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the sponsor of Teen-LABS at NIH. We hope to learn whether or not bariatric surgery is suitable for teens and if it will help them remain at a healthy weight over the long-term. Recent statistics show that... (Science Daily)
Scientists find new genes for Crohn's disease Apr 16, 2007
Stephen P. James, M.D., director of the division of digestive diseases and nutrition at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) agreed, saying that "these important discoveries not only offer new hope for better therapies for patients with Crohn's disease, but they also highlight the promise of the human genome project and subsequent investments by the NIH in large-scale, collaborative research projects to unravel the causes of, and hopefully better... (EurekAlert!)
Insulin -- In Need Of Some Restraint? Mar 9, 2007
The study was funded by the NIDDK and the Clayton Foundation. Note: This story has been adapted from a news release issued by Salk Institute. (Science Daily)
Concerns about NIH 'Common Fund' Feb 14, 2007
"As long as there is this huge Common Fund, and institutes and centers like NIDDK [National Institute of Diabetes and Digestive and Kidney Diseases] are being flat-funded, I look at it as a 'back door' cost to each institute," Jim Schlicht, executive vice president of government affairs and advocacy at the American Diabetes Association, told The Scientist. However, many research advocates support the Common Fund, including representatives of major biomedical research associations who endorsed... (The Scientist)
How Exercise Can Help Prevent Recurring Gestational Diabetes Jan 29, 2007
24 million grant from the National Institutes of Health (NIH) and National Institute of Diabetes and Digestive Kidney Diseases (NIDDK) will fund a team of researchers headed by Chasan-Taber that is investigating the effects of a motivationally tailored, individually targeted 12-week physical activity program on risk of recurrent gestational diabetes (GDM) among women with a history of the condition ... This study builds upon a five-year grant Chasan-Taber currently has, also from the NIH/NIDDK... (Science Daily)
Experimental ragweed therapy offers allergy sufferers longer relief with fewer shots Oct 5, 2006
The research was sponsored by the Immune Tolerance Network, which is funded by the National Institute of Allergy and Infectious Diseases (NIAID) and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), both components of the National Institutes of Health (NIH), and the Juvenile Diabetes Research Foundation International. "As many as 40 million Americans suffer from seasonal allergies caused by airborne pollens produced by grasses, trees and weeds," says NIH Director... (EurekAlert!)
Study finds one in 523 children and adolescents have diabetes Oct 2, 2006
"This study addresses an important gap in our knowledge, providing national estimates on the prevalence of type 1 and type 2 diabetes in children," said Judith Fradkin, M.D., director, Division of Diabetes, Endocrinology and Metabolic Diseases of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK.) ... The study was funded by the U.S. Centers for Disease Control and Prevention and NIDDK and involves six clinical centers in the states of California, Colorado, Hawaii,... (EurekAlert!)
Islet Transplantation Is A Promising Procedure For Certain Patients With Severe Type 1 Diabetes, Clinical Trial Shows Sep 29, 2006
Headquartered at the University of California, San Francisco, the ITN is an international consortium of clinical investigators supported by the National Institute of Allergy and Infectious Diseases (NIAID), the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and the Juvenile Diabetes Research Foundation (JDRF). NIAID and NIDDK are both components of the National Institutes of Health (NIH). (Science Daily)
New Evidence On Risks Associated With Cox-2 Inhibitors And NSAIDs Sep 19, 2006
Corresponding author Mr. Ding was supported by a grant from the National Institute of Diabetes, Digestive, and Kidney Diseases (NIDDK) and by an institutional training grant from the National Cancer Institute, National Institutes of Health. Dr. Song was supported by grants from the NIDDK, National Institutes of Health. (Science Daily)
Colonoscopies save lives through cancer screening Sep 13, 2006
The Montana Standard - Butte, Montana USA. By Paula J. McGarvey for - 09/12/2006. (Montana Standard, MT)
Daily Aspirin Helps Prevent Enlarged Prostate Aug 31, 2006
Health Encyclopedia: Cancer. Prevention, detection and treatment options. (WREG.com, TN)
Sugary drinks are piling on pounds, report says Aug 9, 2006
Americans have sipped and slurped their way to fatness by drinking far more soda and other sugary drinks over the last four decades, a new scientific review concludes. An extra can of soda a day can pile on 15 pounds in a single year, and the "weight of evidence" strongly suggests that this sort of increased consumption is a key reason that more people have gained weight, the researchers say. (AZCentral -- News)
200 years and a cause Aug 3, 2006
Thursday, August 03, 2006. Athlete to catch up to 1806 explorer at the lake. (Camdenton Lake Sun Leader, MO)
Message to older adults: embrace, don't fear the effects of sensible exercise Jul 28, 2006
" The Hopkins study's exercise program followed current guidelines from the American College of Sports Medicine. The study was part of a larger, ongoing trial, called the Senior Hypertension and Physical Exercise study (or SHAPE, for short). It is believed to be the first detailed examination of the guidelines' effectiveness and the separate effects of exercise on blood pressure, heart structure and cardiovascular function, with nearly an equal number of men and women enrolled. A study published... (EurekAlert!)
Diabetic Kids Face Higher Risks Later Jul 26, 2006
The Sentinel Online : Health. Wednesday, July 26, 2006. (Carlisle Sentinel, PA)
Young Type 2 Diabetics More Likely to Suffer Kidney Failure Jul 26, 2006
"The frequency of ESRD [end-stage renal disease] is nearly fivefold higher during mid-life among those diagnosed with diabetes in youth," said study researcher Dr. Robert G. Nelson, a staff clinician for the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) ... More than 100,000 Americans are diagnosed with kidney failure or end-stage renal disease every year, according to the NIDDK. About 45 percent of those cases are caused by diabetes. (Forbes)
Gene Variant Increases Risk Of Type 2 Diabetes; But Healthy Lifestyle Changes Reduce Genetic Risk Jul 24, 2006
D., of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which spearheaded the DPP.. The newly identified gene variant, or allele, is located on chromosome 10q25. (Science Daily)
UVM President Fogel in intensive care Jul 22, 2006
Fatal accidents have been up and down over the years with a 50-year low of 69 just three years ago, but already this year we are at 56 and authorities fear this will be one of the worst years in a generation. -- University of Vermont President Dan Fogel was moved to intensive care Friday after the acute pancreatitis he was hospitalized for earlier in the week took a turn for the worse, officials said. (WCAX.com, VT)
New Clues To How Major Weight-loss Drugs Work Jul 21, 2006
Data presented in this paper were supported by the following: L.K.H. (NIDDK DK065171, American Diabetes Association, and Boston Obesity Nutrition Research Center), N.B. (The Wellcome Trust, UK, ADA-EASD Transatlantic Fellowship, and Boston Obesity Nutrition Research Center), P.G.C. (BBSRC C505291), B.B.L. (NIDDK56116 and DK53301), A.A.B. (NIDDK DK068330 and American Diabetes Association), T.H. (NIDDK DK074386 and DK060711), J.K.E. (NIMH MH061583, NIDDK P01DK056116), and M.A.C. (NIH RR 00163,... (Science Daily)
Four researchers in Bruce Hammock labs win top awards UCD, Jul. 14 Jul 15, 2006
"I'll be working in collaboration with the Hammock Labs, while at NIH with the National Institute for Digestive, Diabetes, and Kidney Diseases (NIDDK)," Weaver said ... Now Weaver will be doing similar work at NIH, collaborating with Hammock and Allan Kirk, chief of the NIDDK transplantation branch. (University of California Newswire, CA)
Study: Type 2 Diabetes Doubles in U.S., Obesity to Blame Jun 21, 2006
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) lists these warning symptoms. Being very thirsty Urinating often Feeling very hungry or tired Losing weight without trying Having sores that heal slowly Having dry, itchy skin Losing the feeling in your feet or having tingling in your feet Having blurry eyesight. (Fox News)
Coffee May Cut Cirrhosis Risk Jun 14, 2006
Her study was funded by the National Institute of Diabetes and Digestive and Kidney Disease and was done in collaboration with Dr. James E. Everhart of the NIDDK.. The mechanism by which coffee might protect the liver "is pretty speculative at this time," Ruhl said. (Forbes)
Increased Sensitivity To Nerve Signals Keeps Diabetes At Bay Jun 7, 2006
This research was supported by the Intramural Research Program of the NIH, NIDDK.. Gautam et al.: "A critical role for ; cell M3 muscarinic acetylcholine receptors in regulating insulin release and blood glucose homeostasis in vivo." Publishing in Cell Metabolism 3, 449-461, June 2006 DOI 10. (Science Daily)
On the diabetes front the news is not good May 30, 2006
Lead researcher Dr. Catherine Cowie, Director of the Diabetes Epidemiology Program at NIDDK says that even though it is now known how type 2 diabetes can be prevented through lifestyle changes that include weight loss and increased physical activity, the disease rates are still climbing. Cowie says more should be done to diagnose the one-in-three people with diabetes who don't know they have it, and the 26 percent of the adult population who have IFG.. (News-Medical.net)
One-Third of U.S. Adults Diabetic, Many Unaware of Disease May 27, 2006
That means that 73 million American have the disease or are on their way to getting it, says Catherine Cowie, PhD, of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) ... Clark is a professor of medicine at Indiana University School of Medicine and is chairman emeritus of the NIDDK s National Diabetes Education Program ... Catherine C. Cowie, PhD, director, Diabetes Epidemiology Program, NIDDK. Charles M. Clark, MD, professor of medicine, Indiana University School of... (Fox News)
One-third of adults with diabetes still don't know they have it May 26, 2006
D., of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). "We're seeing a rising prevalence of diagnosed diabetes that is not substantially offset by a drop in the rate of undiagnosed--about one-third of adults with diabetes still don't know they have it. Another 26 percent of adults have a form of pre-diabetes.". (EurekAlert!)
Fruit Flies Yield Clues To Clinical Heterogeneity Of Early-onset Alzheimer's Disease May 24, 2006
The researchers include Glen A. Seidner of SAIC-Frederick, Inc., National Institutes of Health in Frederick, MD and the University of Pennsylvania School of Medicine in Philadelphia, PA; Yihong Ye of NIDDK, National Institutes of Health in Bethesda, MD and the University of Pennsylvania School of Medicine in Philadelphia, PA; Martha M. Faraday and W. Gregory Alvord of NCI-Frederick, National Institutes of Health in Frederick, MD; Mark E. Fortini of NCI-Frederick, National Institutes of Health in... (Science Daily)
Polycystic kidney disease: MRI provides an early alert to progression May 18, 2006
"There is so much variability in the loss of kidney function among PKD patients, even within families with the same altered gene, that it was assumed that cysts and kidneys must grow at variable rates. So it's quite remarkable to find cysts and kidneys in individuals growing at uniform and predictable rates," said Catherine M. Meyers, M.D., a kidney specialist at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) ... CRISP patients have been asked to stay for another 4... (EurekAlert!)
In Drug Design, A Loose Fit May Be Best Bet May 15, 2006
Chemical knockoffs resembling a key thyroid-related hormone are, in certain cases, more effective than the real thing at activating the target receptor, says a new study conducted in part by researchers at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and the National Institute on Deafness and Other Communication Disorders (NIDCD), two of the National Institutes of Health (NIH) ... GPCRs are the targets of roughly a third of medicines sold today, so if this finding... (Science Daily)
Panel Finds Insufficient Evidence To Recommend For Or Against Maternal-Request Caesarean Delivery Mar 31, 2006
Cosponsors included the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the Office of Research on Women's Health (ORWH), and the National Institute of Nursing Research (NINR). Editor's Note: The original news release can be found. (Science Daily)
Diabetics who control blood sugar today are more likely to have healthy feet and nerves tomorrow Mar 10, 2006
The EDIC sites have received an NIDDK grant to make more precise measurements of neuropathy signs among EDIC participants. And U-M is offering five diabetic neuropathy clinical trials for different types of patients. (EurekAlert!)
