Systems biology research funded with $18 million in grants Oct 3, 2008
The National Institute of General Medical Sciences, part of the National Institutes of Health, has awarded more than $15 million over five years to the University to support the new Chicago Center for Systems Biology. Researchers will study how networks of genes work together to enable cells and organisms to respond to environmental and genetic change. (Univeristy of Chicago Chronicle, IL)
Duke medical team finds genetic link between immune and nerve systems Sep 20, 2008
D., who oversees molecular immunology grants at the National Institute of General Medical Sciences of the National Institutes of Health, said, "Dr. Aballay has made use of the well defined genetics of the roundworm to reveal evidence of cross talk between the nervous system and the innate immune system. Beyond neuronal regulation of immunity, this work opens the door to understanding how neurons may affect other non-neural processes, such as fat storage and longevity.". The study, published in... (EurekAlert!)
DNA Editing Tool Flips Its Target Sep 6, 2008
"Gene silencing via DNA methylation is critical for normal development and for curbing the runaway cell division that characterizes cancer," said Peter Preusch, PhD, who oversees biophysics grants at the National Institute of General Medical Sciences of the National Institutes of Health. "Alterations in methylation patterns are also important for generating embryonic stem-like cells from differentiated cells.". (Science Daily)
Add light to get a new chemical Sep 5, 2008
"What MacMillan has succeeded in doing is to effect a challenging transformation with an efficient, versatile, mild and environmentally benign process," said John Schwab, at the National Institute of General Medical Sciences of the National Institutes of Health. "It's also a beautiful example of taking lessons from nature and applying them to great practical advantage in a non-natural setting," he 00004000 added. (India Times, India -- Health/Science)
Memory, Depression, Insomnia -- And Worms? Aug 5, 2008
Research funding was provided through a grant from the National Institute of General Medical Sciences, an arm of the National Institutes of Health, and OMRF.. Journal reference. (Science Daily)
Researchers Unveil Near-complete Protein Catalog For Mitochondria Jul 15, 2008
This work was supported by a grant from the National Institute of General Medical Sciences, one of the National Institutes of Health. The mitochondrial protein compendium (MitoCarta) is freely available to researchers on the web. (Science Daily)
Dividing Cells Find Their Middle By Following A Protein 'Contour Map' Jul 8, 2008
This remarkable study shows how an enzyme, Aurora B, governs a key step in cell division: positioning of the cleavage furrow, says Richard Rodewald, who oversees cell division grants at the National Institute of General Medical Sciences. This study also underscores the value of the new generation of fluorescent probes for visualizing in exquisite detail the inner workings of living cells. (Science Daily)
Why Cells Starved Of Iron Burn More Glucose Jun 11, 2008
This research was funded by a grant from the Spanish Ministerio de Educacion y Ciencia and FEDER funds from the European Community, an NIH grant from the National Institute of General Medical Sciences and an NIH predoctoral fellowship. Adapted from materials provided by. (Science Daily)
Skin Defects Set Off Alarm With Widespread And Potentially Harmful Effects Jun 2, 2008
Funding from the National Institute of General Medical Sciences, the National Institutes of Health, the National Institute of Diabetes and Digestive and Kidney Disease, the National Institute of Child Health and Human Development and Washington University supported this research. Journal reference. (Science Daily)
New Technique Allows Targeted Inactivation Of Genes In Research Model May 29, 2008
D., who oversees genetic mechanisms grants at the National Institute of General Medical Sciences, The problem is that it s hard to swap in non-functional genes that are inherited by the offspring ... This research was supported by grants from the National Heart, Lung and Blood Institute and the National Institute of General Medical Sciences. (Science Daily)
Men At Increased Risk Of Death From Pneumonia Compared To Women May 20, 2008
The study was funded by the National Institute of General Medical Sciences at the National Institutes of Health. Adapted from materials provided by , via , a service of AAAS.. (Science Daily)
Trauma Patients Suffer Even 12 Months After Injury Mar 21, 2008
The U.S. National Institute of General Medical Sciences has more about. Copyright. (Health-Finder)
Gene That Controls Ozone Resistance Of Plants Could Lead To Drought-resistant Crops Mar 1, 2008
Droughts, elevated ozone levels and other environmental stresses can impact crop yields, said Jean Chin, who oversees membrane protein grants at the National Institute of General Medical Sciences, which partially funded the research ... The study was financed by grants from the National Science Foundation and the National Institute of General Medical Sciences. (Science Daily)
Bacterial Toxin Closes Gate On Immune Response, Researchers Discover Feb 20, 2008
The National Institute of General Medical Sciences provided funding for this research. Adapted from materials provided by. (Science Daily)
Enzyme Structure Reveals New Drug Targets For Cancer And Other Diseases Feb 19, 2008
Scientists funded by the National Institute of General Medical Sciences (NIGMS), part of the National Institutes of Health, now have a clearer understanding of how a key protein controls gene activity and how mutations in the protein may cause disease. The work could provide new avenues to design drugs aimed at cancer, diabetes, HIV, and heart disease. (Science Daily)
Bacterial toxin closes gate on immune response, Penn researchers discover Feb 14, 2008
The National Institute of General Medical Sciences provided funding for this research. This release can be found at. (EurekAlert!)
Gene chips used to distinguish ventilator-associated pneumonia from underlying critical illness Feb 13, 2008
D., who oversees sepsis grants at the National Institute of General Medical Sciences, which partially funded the study. "This innovative approach has the potential to benefit patients, through earlier diagnosis and treatment, and to help hospitals better control outbreaks of pneumonia in patients on ventilator support.". (EurekAlert!)
Changing Our Clocks: New Research Explores How Our Bodies Keep Time Feb 12, 2008
The National Institute of General Medical Sciences, a component of the National Institutes of Health, supported these basic research studies and supports others on circadian rhythms research. Gaining Weight. (Science Daily)
New Target For Preventing And Treating Flu Discovered Feb 7, 2008
"The crystal structures of influenza M2 with and without the anti-influenza drug help us understand the molecular basis of drug resistance, which is a serious problem in treating the flu," said Jean Chin, PhD, who oversees grants on membrane proteins at the National Institute of General Medical Sciences, which in part funded this research. "The findings will inform scientists working to design the next generation of antivirals.". (Science Daily)
Penn researchers discover new target for preventing and treating flu Jan 31, 2008
" The structure revealed that there is a pocket in the channel next to the location where amantadine fits that is conserved in all influenza A viruses. This newly discovered space could be the target for new drugs. "Inhibitors that target this cavity adjacent to two highly conserved amino acids in M2 might reclaim the M2-blocking class of drugs so that ongoing endemic outbreaks and future pandemics of this deadly virus might be prevented and treated," says DeGrado. "The crystal structures of... (EurekAlert!)
Santa comes to science Dec 22, 2007
National Institute of General Medical Sciences, Protein Structure Initiative G. Flores, "Why do Christmas trees survive?" The Scientist, December 23, 2005. B. Morgan, "Spreading fungus, not cheer," The Scientist, March 23, 2004. (The Scientist)
Identification of new genes shows a complex path to cell death Dec 15, 2007
Can a tiny winged insects salivary glands really tell us about processes relevant to human disease" Yes, according to a new study by researchers at the University of Massachusetts Medical School (UMMS), who gained new insights into autophagya cellular degradation process associated with a form of programmed cell deathby studying the salivary gland cells of the fruit fly. Since its initial discovery in the 1960s, programmed cell death has been a primary focus of studies for investigators... (EurekAlert!)
Algae Produces Novel Cystic Fibrosis Drug Nov 30, 2007
What Jamison has done is very impressive because he has managed to make this core so easily and so efficiently and so specifically, said John Schwab, a program director at the National Institute of General Medical Sciences, which provided funding for research. It s a big advance. (Fox News)
Study Shows Cholera Can be Controlled With Oral Vaccines Nov 27, 2007
The research was supported by the Diseases of the Most Impoverished (DOMI) Program of the Bill da Gates Foundation, a grant from the National Institute of General Medical Sciences Models of Infectious Disease Agent Study (MIDAS), and the U.S. National Institute of Allergy and Infectious Diseases. At Fred Hutchinson Cancer Research Center, our interdisciplinary teams of world-renowned scientists and humanitarians work together to prevent, diagnose and treat cancer, HIV/AIDS and other diseases. (PR Newswire)
"Knockout mice" designers win Nobel Prize Oct 9, 2007
Jeremy Berg, director of the U.S. National Institute of General Medical Sciences, which helped fund the work, said using embryonic stem cells was fundamental to the discovery. Scientists now are working with human embryonic stem cells but the research is controversial because some people oppose the manipulation of human embryos. (Scientific American)
Capecchi, Smithies and Evans share the Nobel Oct 9, 2007
"People have been expecting this since the 1990s," said Jeremy M. Berg, director of The National Institute of General Medical Sciences. "The surprise is that they hadn't won it before." The trio started from different lines of research, but in the 1980s, their work began to converge. (The Scientist)
Science: Medicine Nobel goes to 3 for 'designer mice' Oct 9, 2007
Embryonic stem cells were key, Dr. Jeremy Berg, director of the U.S. National Institute of General Medical Sciences, which funded some of the work, said in a telephone interview. When you knock out a gene in an embryonic stem cell, you can take the cells and then turn them into a mouse. (San Diego Union-Tribune)
MIT model could improve some drugs' effectiveness Sep 24, 2007
Making drugs out of huge, complicated molecules like antibodies is incredibly hard, said Janna Wehrle, who oversees computational biology grants at the National Institute of General Medical Sciences, which partially supported the research. Dr. (EurekAlert!)
Specific brain protein required for nerve cell connections to form and function Sep 6, 2007
"This finding now gives us the opportunity to see what job neurexin performs within the cell, so that we can gain a better insight into what can go wrong in the nervous system when neurexin function is lost said Dr. Manzoor Bhat, associate professor of cell and molecular physiology in the UNC School of Medicine and senior author of the study. The study, published online September 6, 2007, in the journal Neuron, is the first to successfully demonstrate in a Drosophila model the consequences that... (EurekAlert!)
Baylor, M.D. Anderson to share in $8.7M grant Sep 5, 2007
7 million five-year grant from the National Institute of General Medical Sciences has been awarded to scientists from , The in Houston and UT Southwestern Medical School in Dallas to conduct human embryonic stem cell research. "We hope this will become a regional cornerstone for human embryonic stem cell research," said Dr. Margaret Goodell, professor of pediatrics and molecular and human genetics at Baylor. (Houston Business Journal, TX)
Secrets Of Red Tide Revealed Sep 1, 2007
The research was funded by the National Institute of General Medical Sciences, Merck Research Laboratories, Boehringer Ingelheim, and MIT.. "This is an elegant piece of work with multiple levels of impact," said John Schwab, who manages organic chemistry research for the National Institute of General Medical Sciences. (Science Daily)
Bird flu tracked person to person in "Hutch" program Aug 31, 2007
The TransStat software developed from the researchers' statistical models will be available soon online through MIDAS, the Models of Infectious Disease Agent Study, supported by the National Institute of General Medical Sciences. The model uses data about certain specifics of an outbreak, including the duration of the outbreak, the virus' incubation period, and the length of the infectious period. (Seattle Times)
Researchers confirm theory on red tide algae toxins Aug 31, 2007
The research was funded by the National Institute of General Medical Sciences, Merck Research Laboratories, Boehringer Ingelheim and MIT.. . (International Herald Tribune)
MIT researchers achieve breakthrough on red tide toxin Aug 31, 2007
"This is an elegant piece of work," said John Schwab of the National Institute of General Medical Sciences, which helped fund the research. Scott Allen can be reached at. (Boston Globe -- Nation)
Scientists recreate red tide toxins Aug 31, 2007
The research was funded by the National Institute of General Medical Sciences, Merck Research Laboratories, Boehringer Ingelheim and MIT. All rights reserved. This copyrighted material may not be published, broadcast or redistributed in any manner. (Herald Online, SC -- Health)
Humans Spread Bird Flu To Humans in Indonesia Aug 30, 2007
This tool soon will be available online free of charge via MIDAS, the Models of Infectious Disease Agent Study, which is supported by the National Institute of General Medical Sciences ... The study was funded and supported by the National Institute of General Medical Sciences MIDAS network and the National Institute of Allergy and Infectious Diseases. (Science Daily)
Software confirms human-to-human spread of avian flu Aug 30, 2007
The study will be published next month in the Centers for Disease Control and Prevention journal called "Emerging Infectious Diseases." The study was funded by the National Institute of General Medical Sciences' MIDAS network and the National Institute of Allergy and Infectious Diseases. MIDAS (Models of Infectious Disease Study) will make the data available for other researchers to study after the publication, and TranStat will also be made available free online. (EETimes)
Human Testes May Multiply Mutations Aug 29, 2007
Funding for the research came from the Ellison Medical Foundation and the National Institute of General Medical Sciences. Note: This story has been adapted from a news release issued by University of Southern California. (Science Daily)
How To Predict Cells' Response To Drugs Aug 3, 2007
The research was funded by the National Institute of General Medical Sciences Cell Decision Processes Center, the University of California at Santa Barbara-CalTech-MIT Institute for Collaborative Biotechnologies and the MIT Biotechnology Process Engineering Center. Note: This story has been adapted from a news release issued by Massachusetts Institute of Technology. (Science Daily)
UCI awarded $14.4 million to support systems biology center UCI, Aug. 01 Aug 2, 2007
The UCI center is being funded by the National Institute of General Medical Sciences (NIGMS), one of the National Institutes of Health (NIH). It will be the only one of its kind in California. (University of California Newswire, CA)
Strains of laboratory mice more varied than previously thought Jul 30, 2007
With support from the National Institute of General Medical Sciences, part of the National Institutes of Health, the researchers analyzed lineage and sequence variation based on the most extensive genetic data sets of inbred mouse strains. This information came from the National Institute of Environmental Health Sciences (NIEHS). (EurekAlert!)
Hepatitis C helicase unwinds DNA in a spring-loaded, 3-step process Jul 27, 2007
Funding for this research was provided by the National Institute of General Medical Sciences at the National Institutes of Health. To view or subscribe to the RSS feed for Science News at Illinois, please go to. (EurekAlert!)
Researchers Use New Approach To Predict Protein Function Jul 18, 2007
This study was supported by the National Institute of General Medical Sciences at the National Institutes of Health. Note: This story has been adapted from a news release issued by University of Illinois at Urbana-Champaign. (Science Daily)
Translating form into function Jul 2, 2007
Ricardo; and Marti-Arbona, a graduate student at Texas AThe research is supported in part by the National Institute of General Medical Sciences, one of the National Institutes of Health. . (EurekAlert!)
Structure Of Protein Altered In Autism Jun 13, 2007
D., program director with the National Institute of General Medical Sciences, part of the National Institutes of Health, which partly supported the study. "The work suggests that genetic mutations that alter the shape or folding of adhesion proteins in the nervous system influence their interactions. This is another example of how research on basic biological questions, such as the three-dimensional structures of proteins in the brain, can yield valuable medical insights.". (Science Daily)
In A First, Scientists Develop Tiny Implantable Biocomputers May 23, 2007
Their research is supported by Harvard University and a center grant from the National Institute of General Medical Sciences. The results will be published in the journal Nature Biotechnology. (Science Daily)
Chemists strike gold with new gold catalysts Mar 24, 2007
" ### The coauthor with Toste on the Nature review is UC Berkeley graduate student David J. Gorin. The research was funded by the National Institute of General Medical Sciences of the National Institutes of Health, and by Merck Research Laboratories, Bristol-Myers Squibb, Amgen Inc., DuPont, GlaxoSmithKline, Eli Lilly Pfizer, AstraZeneca, Abbott, Boehringer Ingelheim, Novartis and Roche. Toste is the Chevron Professor of Chemistry at UC Berkeley.. (EurekAlert!)
Correcting RNA Splicing May Help Treat Spinal Muscular Atrophy Mar 14, 2007
D. of the National Institute of General Medical Sciences, which partially supported Krainer's research. "This work brings us one step closer to that goal.". (Science Daily)
Destructive Enzyme Shows A Benevolent Side Jan 13, 2007
Funding from the National Institute of General Medical Sciences supported this research. Schoenberg collaborated on this study with Nancy Kedersha at Brigham and Women's Hospital and Harvard Medical School. (Science Daily)
