Progressive Multifocal Leukoencephalopathy after Natalizumab Monotherapy Sep 10, 2009
From the Neurology Unit, Division of Internal Medicine (H.L., J.B., C.M.), the Department of Radiology (A.H.), and the Neuroimmunology Unit, Department of Clinical Neuroscience (T.O.), Danderyd Hospital, Karolinska Institutet, Stockholm; and the Laboratory of Molecular Medicine and Neuroscience, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD (E.O.M., C.R.). Address reprint requests to Dr. Lind. (New England Journal of Medicine)
Reemergence of PML in Natalizumab-Treated Patients — New Cases, Same Concerns Sep 10, 2009
From the Laboratory of Molecular Medicine and Neuroscience, National Institute of Neurological Disorders and Stroke, Bethesda, MD.. . (New England Journal of Medicine)
Scientists Identify Genes Linked To Lou Gehrig's Disease Sep 10, 2009
The data set they analyzed was provided by National Institute of Neurological Disorders and Stroke (NINDS) Human Genetics Resource Center at the Coriell Institute, a publicly funded "bank" or repository for human cells, DNA samples, clinical data, and other information that aims to accelerate research on the genetics of nervous system disorders. Ideally, we should confirm our results in a second data set, but we don t have one available, Sha says. (Science Daily)
Mayo researchers link gene to Parkinsons Sep 2, 2009
The study was funded by grants from the National Institute of Neurological Disorders and Stroke and the Mayo Foundation Research Committee. Reader Comments. (Jacksonville Business Journal, FL)
UF scientists construct 'off switch' for Parkinson therapy Aug 29, 2009
The work was supported by the National Institute of Neurological Disorders and Stroke. . (EurekAlert!)
High Blood Pressure Linked To Memory Problems In Middle Age Aug 27, 2009
The study was supported by the National Institute of Neurological Disorders and Stroke (NINDS). "The REGARDS study is one of the largest population-based studies of risk factors for stroke. These latest data suggest that higher blood pressure may be a risk factor for cognitive decline, but further studies will be necessary to understand the cause-effect relationship," said Walter J. Koroshetz, MD, deputy director of NINDS and Fellow of the American Academy of Neurology. (Science Daily)
High Blood Pressure Linked to Middle-age Memory Lags Aug 26, 2009
The study was supported by the National Institute of Neurological Disorders and Stroke. "The REGARDS study is one of the largest population-based studies of risk factors for stroke. These latest data suggest that higher blood pressure may be a risk factor for cognitive decline, but further studies will be necessary to understand the cause-effect relationship," said Dr. Walter J. Koroshetz, deputy director of the neurological institute and Fellow of the American Academy of Neurology. (Newsmax)
Hypertension Linked to Thinking Problems in Middle Age Aug 26, 2009
That thought was echoed in a statement by Dr. Walter J. Koroshetz, deputy director of the U.S. National Institute of Neurological Disorders and Stroke, which has supported the stroke study. "The National Institutes of Health is now organizing a large clinical trial to evaluate whether aggressive blood pressure lowering can decrease a number of important health outcomes, including cognitive decline," the Koroshetz statement said. (MEDLINEplus)
Fragile period of childhood brain development could underlie epilepsy Aug 24, 2009
" ### This study was supported in part by grants from the U.S. National Institute of Neurological Disorders and Stroke, the Nancy Lurie Marks Family Foundation, and Autism Speaks/US National Alliance for Autism Research. Study coauthors include BIDMC investigators Yu-Dong Zhou (first author), Sanghoon Lee, Zhe Jin and Stephen E.P. Smith, and Moriah Wright of Tufts University School of Medicine. Beth Israel Deaconess Medical Center is a patient care, teaching and research affiliate of Harvard... (EurekAlert!)
ASU adding autism track for students Aug 23, 2009
The National Institute of Neurological Disorders and Stroke describes people with autism as having some common conditions: a problem with spoken and/or non-verbal communication, an impaired ability to socialize with others and "unusual, repetitive or limited interests and activities." A child with autism often insists on rigid routines and displays repetitive behaviors such as obsessively arranging objects or focusing intently on one object. The disorder has become rampant, with one out of every... (AZCentral -- News)
Low Choline Levels In Pregnant Women Raise Babies' Risk For Brain And Spinal-cord Defects, Study Shows Aug 18, 2009
The study was funded by grants from the U.S. Centers for Disease Control and Prevention, the National Institute of Neurological Disorders and Stroke, and the Foundation to Promote Research into Functional Vitamin B12 Deficiency. Adapted from materials provided by. (Science Daily)
GEORGE B. KAUFFMAN: Alzheimer's: The plague of baby boomers? Aug 15, 2009
3 million grant award from the National Institute of Neurological Disorders and Stroke (NINDS) for development of a vaccine for Alzheimers disease. Ichor is collaborating on the project with Dr. Michael Agadjanyan, Vice President and Head of Immunology at the Institute for Molecular Medicine (IMM), Huntington Beach, CA; Dr. David H. Cribbs, Professor, Department of Neurology and Institute for Memory Impairments and Neurological Disorders at the University of California, Irvine (UCI); and Dr.... (Fresno Bee -- Opinion)
System to treat stroke victims has long reach Aug 14, 2009
Getting a clot-buster within three hours increased by 33 percent the number of patients free from disability three months later, according to the National Institute of Neurological Disorders and Stroke. "It's our best treatment for stroke, actually to bring people back to normal or to a good outcome from their stroke," said Kenneth Gaines, the chairman of the Department of Neurology at Ochsner Clinic Foundation. (The Augusta Chronicle)
Is There Long-term Brain Damage After Bypass Surgery? More Evidence Puts The Blame On Heart Disease Aug 7, 2009
Funding support for this study was provided by the U.S. National Institute of Neurological Disorders and Stroke, a member of the U.S. National Institutes of Health, and the Dana Foundation. Besides McKhann, Baumgartner, and Selnes, other researchers involved in this study, conducted from 1997 through 2008, were Maura Grega, M.S.N.; Maryanne Bailey, M.P.H.; Luu D. Pham, M.Sc. (Science Daily)
Why We Learn More From Our Successes Aug 3, 2009
This work is supported by National Institute of Neurological Disorders and Stroke and the Tourette's Syndrome Association. Adapted from materials provided by. (Science Daily)
Novel Drug Discovery Tool Could Identify Promising New Therapies For Parkinson's Disease Jul 18, 2009
D., a program director at NIH's National Institute of Neurological Disorders and Stroke (NINDS). "A key step for the future will be to identify the cellular pathways that are affected by these cyclic peptides." This research was funded by the National Institutes of Health. (Science Daily)
Higher Education Level, Greater Disability Associated With Treatment Timing In Parkinson's Disease Jul 17, 2009
This study was supported by the National Institute of Neurological Disorders and Stroke, National Institutes of Health. Journal reference. (Science Daily)
Smoking Associated With More Rapid Progression Of Multiple Sclerosis Jul 15, 2009
This study was supported by the Partners Multiple Sclerosis Center and by a grant from the National Institute of Neurological Disorders and Stroke, National Institutes of Health Molecular Epidemiology of Epstein-Barr Virus and Multiple Sclerosis (Dr. Ascherio). (Science Daily)
'Fridge' improving with help from family, friends Jul 3, 2009
The National Institute of Neurological Disorders and Stroke says on its Web site that there's no known cure for Guillain-Barre. Perry's Chicago Bears coach, Mike Ditka, saw something wrong in February when his former lineman showed up for an autograph session at Rosemont, Ill. (MSNBC -- Sports)
Family comes to the rescue of 'The Fridge' Jun 30, 2009
Source: National Institute of Neurological Disorders and Stroke/National Institutes of Health. More Sports. (News & Observer -- Sports)
Carpal tunnel syndrome nags Arroyo Jun 29, 2009
But there is little clinical data to prove whether repetitive and forceful movements of the hand and wrist during work or leisure activities can cause carpal tunnel according to the National Institute of Neurological Disorders and Strokes Web site. The 32-year-old said he is looking into offseason surgery to fix the problem. (MLB.com -- Cincinnati Reds)
DNA template could explain evolutionary shifts Jun 22, 2009
Funding for this work came from the Charcot Marie Tooth Association and the National Institute of Neurological Disorders and Stroke. When the embargo lifts, the article will be available at. (EurekAlert!)
People With Huntington's Report Discrimination Jun 16, 2009
A child of someone with Huntington's has a 50-50 chance of inheriting the gene, according to the U.S. National Institute of Neurological Disorders and Stroke. The researchers also reported that about 7 percent of the study participants said they'd faced discrimination in employment, nearly 9 percent said they felt it in a health-care setting and about 4 percent said they had been discriminated against in a public setting. (MEDLINEplus)
Two Signals -- From Within And Out Of Cell -- Specify Motor Neuron Differentiation Jun 16, 2009
Funding for this work came from the National Institute of Neurological Disorders and Stroke, the PEW Trust, the March of Dimes Foundation and the Intellectual and Developmental Disability Research Centers. Journal reference. (Science Daily)
Scientists find culprit to Huntington's disease Jun 6, 2009
"The answers in one disease may have implications for another," noted Koroshetz of NIH's National Institute of Neurological Disorders and Stroke. "There's been people on both sides of the fence. This story plays to the role of the aggregates as not being the major problem but the soluble protein as being the major problem.". (San Francisco Chronicle -- Science)
Capturing The Birth Of A Synapse: Mechanism Locking Two Neurons Found May 29, 2009
The National Institute of Neurological Disorders and Stroke (National Institutes of Health), the Florida-based non-profit Whitehall Foundation and New York-based Autism Speaks, the nation's largest autism science and advocacy organization, funded Washbourne's research. McAllister was funded by the Pew Charitable Trusts and National Eye Institute. (Science Daily)
Owie! Halt pizza burn, other pains May 25, 2009
"It keeps your wrist neutral, which prevents further compression and irritation of the nerve," says Tanya J. Lehky, M.D., director of the Clinical EMG Lab at the NIH's National Institute of Neurological Disorders and Stroke. More stories from Men's Health. (MSNBC -- Health)
UCLA study shows traumatic brain injury haunts children for years May 14, 2009
" ### The research was funded by the National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health, and by the Della Martin Foundation. The authors report no conflict of interest. The UCLA Department of Psychiatry and Biobehavioral Sciences is the home within the David Geffen School of Medicine for faculty who are expert in the origins of and treatments for disorders of complex human behavior. It is part of the Semel Institute for Neuroscience and Human... (EurekAlert!)
Family honored for courage in face of disease May 9, 2009
ALS is a rapidly progressive, invariably fatal neurological disease that attacks the nerve cells (neurons) responsible for controlling voluntary muscles, according to the National Institute of Neurological Disorders and Stroke. Confined to a motorized wheelchair, Scherer can t lift his arms. (Mattoon Journal-Gazette, IL)
Narcolepsy is an autoimmune disorder, Stanford researcher says May 4, 2009
"This is a very important finding," said Merrill Mitler, PhD, a sleep disorders expert and program director at the National Institute of Neurological Disorders and Stroke, who was not involved in the study. "It puts in place another piece of the puzzle and shows a way to link [this gene variant] to hypocretin-containing neurons via an autoimmune attack.". (EurekAlert!)
Autism, Asperger's Syndrome and Fac... Apr 20, 2009
National Institute of Neurological Disorders and Stroke (NINDS). (14 February 2007). (Suite101.com)
* One unwanted trickle-down effect: child abuse and murder Apr 18, 2009
Some doctors term such cases shaken-baby syndrome, which the National Institute of Neurological Disorders and Stroke says bear distinct signs: brain hemorrhaging, retinal hemorrhaging and damage to the spine, neck or ribs. Because of a babys relatively large head and weak neck, shaking makes the fragile brain bounce back and forth inside the skull and causes bruising, swelling and bleeding, which can lead to permanent, severe brain damage or death, it says. (Taipei Times, Taiwan -- World Business)
Child Abuse Spikes as U.S. Economy Founders Apr 18, 2009
" Some doctors term such cases "shaken-baby syndrome," which the National Institute of Neurological Disorders and Stroke says bear distinct signs: brain hemorrhaging, retinal hemorrhaging and damage to the spine, neck or ribs. Because of a baby's relatively large head and weak neck, shaking "makes the fragile brain bounce back and forth inside the skull and causes bruising, swelling and bleeding, which can lead to permanent, severe brain damage or death," it says. "We saw a huge influx of... (MEDLINEplus)
Researchers discover genetic variants tied to stroke Apr 16, 2009
Walter Koroshetz, deputy director of the U.S. National Institute of Neurological Disorders and Stroke, which supported the study, said in a statement that the findings are "not sufficiently high to make an individual change their stroke prevention plan.". But they "will lead scientists to direct their attention to new, important biologic mechanisms and hopefully new treatments to prevent stroke," Koroshetz noted. (Xinhuanet, China)
Human ES cells progress slowly in myelin's direction Apr 9, 2009
The authors are from the Departments of Anatomy and Neurology at the School of Medicine and Public Health, Waisman Center (), University of Wisconsin-Madison, USA. They are funded by the National Institute of Neurological Disorders and Stroke and The National Multiple Sclerosis Society. . (EurekAlert!)
Parkinsons group members face disease together Apr 8, 2009
The National Institute of Neurological Disorders and Stroke (NINDS) continues to conduct PD research in laboratories at the National Institutes of Health (NIH), as well as supporting additional research through grants to major medical institutions in the United States. Scientists also continue to look for the cause of PD as they examine possible environmental factors such as toxins that may trigger the disorder, as well as studying genetic factors to determine what role defective genes may play. (Gaylord Herald Times, MI)
Oxycodone Effective Against Shingles Pain Apr 8, 2009
Funding from the National Institute of Neurological Disorders and Stroke provided the impetus for the study, which was funded directly by Novartis and Pfizer. Endo, Novartis, Pfizer, and Purdue Pharma provided medications and placebo for the study. (Science Daily)
Obesity, restless legs syndrome linked Apr 7, 2009
Source: National Institute of Neurological Disorders and Stroke. DAILY HEALTH BLOG. (USA Today -- News)
'Matchmaker' Protein Maintains Neuronal Balance Apr 2, 2009
Funding for this research came from the National Institute of Neurological Disorders and Stroke, the Pew Scholars in Biomedical Science Program, the March of Dimes Foundation and the BCM Intellectual and Developmental Disabilities Research Center. Journal reference. (Science Daily)
Stroke patients benefit from Botox Mar 26, 2009
Dr. Mark Hallett, chief of the motor control section of the National Institute of Neurological Disorders and Stroke, says he uses both electromyography and ultrasound when injecting patients. "A number of authorities feel that if they get close, that's good enough," Dr. Hallett said. (International Herald Tribune)
Experimental Parkinson's therapy may have robust weight-loss effect Mar 25, 2009
The work was supported by the National Institute of Neurological Disorders and Stroke and by the Medical Research Service of the Department of Veterans Affairs. . (EurekAlert!)
Astrocytes help separate man from mouse Mar 24, 2009
The work was funded by the G. Harold and Leila Y. Mathers Charitable Foundation and by the National Institute of Neurological Disorders and Stroke. . (EurekAlert!)
South Elementary students raise money for wheelchair Mar 20, 2009
According to the National Institute of Neurological Disorders and Stroke, the muscular dystrophies are a group of more than 30 genetic diseases characterized by progressive weakness and degeneration of the skeletal muscles that control movement. Many forms of MD are found in children but others may not be discovered until middle age or later in life. (Yanceyville Caswell Messenger, NC)
Zapping spinal cord may alleviate Parkinsons Mar 20, 2009
There's increasing if circumstantial evidence that rhythmic waves of brain activity, called oscillations, play a role in Parkinson's movement problems and that interrupting those abnormal waves allows the more normal, symphony-like brain cell firing to resume, said Dr. Walter Koroshetz, deputy director of the National Institute of Neurological Disorders and Stroke, which helped fund the work. The spinal cord stimulation appears to have sent a signal up to the brain that interrupted those... (MSNBC -- Health)
Weighing The Options After Life-altering Stroke Mar 19, 2009
People who haven't experienced a health condition, such as stroke, almost always provide a lower estimate of their quality of life compared to people who are actually living with that condition or disease," Holloway added. Kelly has witnessed the same dynamics himself. "People have a remarkable ability to compensate for whatever problems they face," said Kelly, whose fellowship is supported by the National Institute of Neurological Disorders and Stroke. "Oftentimes, the fear of the unknown, and... (Science Daily)
* Moral arguments come up short in stem cell debate Mar 17, 2009
People need a fairy tale, Ronald McKay, a stem cell researcher at the National Institute of Neurological Disorders and Stroke, explained to the Washington Post in 2004. Recently, Nicholas Wade in the Science section of the New York Times summed this all up: Members of Congress and advocates for fighting diseases have long spoken of human embryonic stem cell research as if it were a sure avenue to quick cures for intractable afflictions. (Taipei Times, Taiwan -- Business)
Religion, a product of human evolved brains Mar 12, 2009
According to the researchers of US National Institute of Neurological Disorders and Stroke in Maryland, such beliefs "light up" the areas of our brain which have evolved most recently, such as those involved in imagination, memory and "theory of mind" -- the recognition that other people and living things can have their own thoughts and intentions. "They don't tell us about the existence of a higher order power like God. They only address how the mind and brain work in tandem to allow us to have... (India Times, India -- Health/Science)
Did Evolution Allow Religion? Mar 11, 2009
"We're interested to find where in the brain belief systems are represented, particularly those that appear uniquely human," says lead researcher, Jordan Grafman of the US National Institute of Neurological Disorders and Stroke in Bethesda, Maryland. The researchers found that such beliefs "light up" the areas of our brain which have evolved most recently, such as those involved in imagination, memory and "theory of mind" -- the recognition that other people and living things can have their own... (ABC News)
Women Less Likely To Have A Stroke After Mini-stroke Mar 4, 2009
It was funded by the National Institute of Neurological Disorders and Stroke. Journal reference. (Science Daily)
Even Mild Strokes Can Do Harm Mar 3, 2009
Some 4 million Americans are living with the effects of stroke, says the National Institute of Neurological Disorders and Stroke. What's more, it's estimated that as many as 10 million Americans have strokes without ever knowing it. (MEDLINEplus)
Deep Brain Stimulation Helps Those with Advanced Parkinson's Feb 7, 2009
The trial was funded by the VA, the U.S. National Institute of Neurological Disorders and Stroke, and Medtronic. As Parkinson's advances, motor symptoms are often accompanied by anxiety, depression and other non-motor symptoms. (MEDLINEplus)
Only Half of Multiple Sclerosis Patients Respond to Interferon Therapy Feb 7, 2009
For the study, researchers led by Dr. Francesca Bagnato, of the U.S. National Institute of Neurological Disorders and Stroke, looked at brain MRI scans of 15 MS patients who were given shots of interferon -- a standard MS treatment -- every other day over 36 months. The researchers found that eight patients saw a 60 percent reduction in their brain lesions, which are typical of MS; these patients were classified as "responders." Among the seven "non-responders," three had an initial reduction in... (MEDLINEplus)
Family History of Aneurysm Raises Stroke Risk for Smokers Feb 7, 2009
The study, backed by the U.S. National Institute of Neurological Disorders and Stroke and published in the Jan. 6 issue of Neurology, found that these smokers were more than six times more likely to suffer a particular type of stroke, called a subarachnoid hemorrhage, than were those who did not smoke and did not have a family history of stroke or brain aneurysm. A subarachnoid hemorrhage is a bleeding type of stroke that's deadly 35 to 40 percent of the time, according to the study. (MEDLINEplus)
