What does your feet reveal Oct 31, 2009
Onychomycosis can persist painlessly for years. Nails may also smell bad and turn dark. (India Times, India)
Human Dectin-1 Deficiency and Mucocutaneous Fungal Infections Oct 29, 2009
We describe a family in which four women who were affected by either recurrent vulvovaginal candidiasis or onychomycosis had the early-stop-codon mutation Tyr238X in the -glucan receptor dectin-1. The mutated form of dectin-1 was poorly expressed, did not mediate -glucan binding, and led to defective production of cytokines (interleukin-17, tumor necrosis factor, and interleukin-6) after stimulation with -glucan or Candida albicans. (New England Journal of Medicine)
NovaBay Pharmaceuticals Announces Lead Anti-infective Product Candidate, NVC-422, Shown to be Effective in Treating Topical Fungal Infection Mar 8, 2009
"The significant clinical and mycological efficacy rates shown in this study demonstrate that topical NVC-422 penetrates the skin and hair at the infection site indicating that it has the potential to target and eliminate skin infections, including onychomycosis, tinea pedis, and tinea capitis. Importantly, these data provide strong support for continuing to develop NVC-422 for fungal infections.". NVC-422 is the most advanced of a series of compounds from a new class of drugs that mimics the... (PR Newswire)
