Oral Health and the Immune System Aug 10, 2008
Researchers at Harvard School of Public Health have also determined that poor oral health is associated with an increased risk of pancreatic cancer. Swedish researchers have also found that patients with gum disease were twice as likely to have cardiovascular disease, dangerous lipid levels, and higher levels of cytokines known as leukotrienes. (Suite101.com)
Touchdowns thrilling, but touching lives fulfulling Aug 10, 2008
" In 1999, at the age of 54, his mom, Betty Barnes, was diagnosed with pancreatic cancer. She died three months later. Going through such a life-draining experience with her, watching a 5-foot-11 athletic woman whither to skin and bone, changed Burkett. "Think about it. How many people do you really feel so deeply about, the way you feel about your mother. (The Clarion-Ledger)
Thanks a million for record effort Aug 10, 2008
Meanwhile Wollongong's Margaret Royall has defied the odds and major surgery for pancreatic cancer to compete. Fewer than 7 per cent of patients survive the disease, yet, three years after her surgery and despite being unable to eat many foods, she will walk to Bondi to raise funds for Cancer Council NSW.. (Sydney Morning Herald -- Australia)
High doses of vitamin C injections slow tumor growth Aug 8, 2008
The research showed high dose injections of the vitamin, also known as ascorbate or ascorbic acid, reduced tumor weight and growth rate by about 50 percent in mouse models of brain, ovarian, and pancreatic cancers ... The scientists further tested high dose injections of vitamin C in immune-deficient mice with rapidly spreading ovarian, pancreatic and glioblastoma tumors and discovered that mice that received vitamin C injections reduced tumor growth and weight by 41 to 53 percent. (Food Consumer)
Researchers Unveil Vital Key To Cancer Aug 8, 2008
The team hopes its work will allow chemists to design an anti-cancer drug with fewer side effects, allowing scientists to assess the relative importance of Mps1 inhibition in different disease indications, including those that are currently hard to treat such as lung and pancreatic cancers. Dr Eyers, whose findings are published in the Journal of Biological Chemistry (August 2008), said: The crystallalographic structures of only a few key mitotic kinases are currently known so we are very early... (Science Daily)
Catalogue of diseased stem cells unveiled Aug 8, 2008
One thing his lab will do is try to make pancreatic beta cells the cells that make insulin, and which are destroyed in type 1 diabetes and study them to see what may be different among patients with the disease. While the cells are an alternative to the more controversial embryonic stem cells, taken from a human embryo, the doctors are adamant that they do not replace them. (Globe and Mail)
Rock Music Menu: Robert Hazard: Local legend is lost Aug 8, 2008
Sadly, he never made it, passing away this Tuesday due to complications from pancreatic cancer. A chance meeting at the legendary South Street staple J.C. Dobbs with Rolling Stone magazine's Kurt Loder led to Hazard's big break when the journalist penned a favorable article few months later. (The Delaware County Times, PA)
New Gene Therapy Kills Pancreatic Cancer Cells Aug 7, 2008
6, 2008) Researchers at the Virginia Commonwealth University Massey Cancer Center and the VCU Institute of Molecular Medicine have published findings that implicate a new chemoprevention gene therapy (CGT) for preventing and treating pancreatic cancer, one of the most lethal and treatment-resistant forms of cancer ... In the July issue of Molecular Cancer Therapeutics, the researchers showed that combining a dietary agent with a gene-delivered cytokine effectively eliminates human pancreatic... (Science Daily)
Panel Urges End to Prostate Screenings for Men Over 75 Aug 6, 2008
"It s not like pancreatic cancer, which is a very aggressive cancer," Fisch said. "Prostate cancer has different grades, severities. The vast majority that s detected does not kill you. If you pick up a high-grade cancer, yes, I recommend treatment such as surgery, radiation or a combination.". (Fox News)
New Treatment Combination Safe For Pancreatic Cancer Patients Aug 6, 2008
ScienceDaily (June 6, 2008) Treating pancreatic cancer with a combination of chemotherapy, biotherapy and radiotherapy prior to surgery is safe and may be beneficial for patients, according to a University of Pittsburgh Cancer Institute (UPCI) study presented at the 44th annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago ... In a preliminary study, physicians from the Pancreatic Cancer Center of the University of Pittsburgh Medical Center (UPMC) Cancer Centers examined... (Yahoo News -- Cancer)
Report: Insulin Resistance May Lead to Cancer Aug 6, 2008
Researchers found that an insulin-like growth factor can fuel cancer cells, especially the cells linked to colon, breast, endometrial, and pancreatic cancer. You likely have insulin resistance if your blood sugar levels are above 100, even when you have not eaten for eight hours. (WOKR13 Rochester)
Vitamin C 'slows cancer growth' Aug 6, 2008
The jab halved the size of brain, ovarian and pancreatic tumours in mice, reported the journal Proceedings of the National Academy of Sciences. However, Cancer Research UK said other studies suggested large vitamin C doses may interfere with cancer treatment. (BBC News -- Health)
Sorting Out Coffee's Contradictions Aug 6, 2008
Panic swept this coffee-dependent nation in 1981 when a Harvard study tied the drink to a higher risk of pancreatic cancer ... In an international review of 66 studies last year, scientists found coffee drinking had little if any effect on the risk of developing pancreatic or kidney cancer. (Atlanta Journal-Constitution -- Health)
YM BIOSCIENCES REPORTS PHASE II DATA FOR NIMOTUZUMAB IN METASTATIC COLORECTAL CANCER Aug 5, 2008
Nimotuzumab is currently being evaluated in two Phase III trials as a first-line treatment for pediatric pontine glioma and adult glioma, a Phase II/III trial as a treatment for pancreatic cancer and the phase II study in colorectal cancer reported on in this release. In addition the drug has been approved for marketing in eight countries and is currently under review for marketing approval by EMEA. About YM BioSciences YM BioSciences Inc. is an oncology company that identifies, develops and... (PR Newswire)
BELLUS Health moves forward on nutraceutical and pharmaceutical fronts - Reports Results for First Half of 2008 Aug 5, 2008
Treatment with NC-503 correlated with the preservation of 40% more pancreatic islet cells secreting insulin than in the control group ... Results from animal studies using a rat model of diabetes and metabolic syndrome have shown that NC-503 decreases the glycemic levels in obese diabetic Zucker rats, when compared to the control group, preserves 40% more pancreatic islet cells secreting insulin than in the control group, and protects kidney function. (Canada Newswire)
Vitamin C Shots Can Beat Cancer Aug 5, 2008
The scientists said in the journal Proceedings of the National Academy of Sciences that daily treatment "significantly decreased growth rates of ovarian, pancreatic and glioblastoma tumours established in mice". They added: "Similar pharmacologic concentrations were readily achieved in humans given ascorbate intravenously. "This data suggests that ascorbate as a prodrug may have benefits in cancers with poor prognosis and limited therapeutic options. (Glasgow Daily Record)
Vitamin C Shows Promise as Cancer Treatment Aug 5, 2008
The nutrient shrunk brain, ovarian and pancreatic tumors in mice ... The mice had ovarian, pancreatic and brain cancer. (Health-Finder)
000029BFVitamin C injections slow tumor growth in mice Aug 5, 2008
WASHINGTON, Aug. 4 (Xinhua) -- High-dose injections of vitamin C, also known as ascorbate or ascorbic acid, reduced tumor weight and growth rate by about 50 percent in mouse models of brain, ovarian, and pancreatic cancers, researchers from the U.S. National Institutes of Health (NIH) report on Monday ... To bypass these normal controls, NIH scientists injected ascorbate into the veins or abdominal cavities of rodents with aggressive brain, ovarian, and pancreatic tumors ... The team then tested... (Xinhuanet, China)
Loneliness Sparks Risk of Dementia Aug 5, 2008
Last Updated: Tuesday 5 August 2008 06:14 GMT. by Published on August 3, 2008 - 0 comments. (TheMedGuru)
Bones offer new hope for diabetes Aug 5, 2008
" However, the team found a novel function of the molecule. Usually, an increase in insulin levels in the blood is accompanied by a decrease in insulin sensitivity. But the authors found osteocalcin boosted both the secretion and the sensitivity to insulin. In mice, increasing the activity of the molecule stimulated pancreatic cells to produce more insulin and at the same time directed fat cells to release a hormone called adiponectin - which improves insulin sensitivity. It also stimulated the... (Yahoo News -- Diabetes)
Vitamin C injections slow cancer in mice: study Aug 5, 2008
Researchers at the National Institutes of Health noted the phenomenon in brain, ovarian and pancreatic cancers, according to findings published in the August 5 issue of the Proceedings of the National Academy of Sciences ... Scientists "injected ascorbate into the veins or abdominal cavities of rodents with aggressive brain, ovarian, and pancreatic tumors," the report said, delivering "up to four grams per kilogram of body weight daily." ... "In immune-deficient mice with rapidly spreading... (Yahoo! Asia News)
Parting words from some 'last lectures' Aug 4, 2008
Randy Pausch, computer science professor at Carnegie Mellon University, on Sept. 18, 2007, a month after learning he had terminal pancreatic cancer. He died July 25. (Boston Globe)
Treatment Corrects Severe Insulin Imbalance In Animal Studies Aug 4, 2008
"This type of congenital hyperinsulinism is caused by mutations in genes that encode important potassium channels in the pancreatic beta cells." The study team, from Children's Hospital and the University of Pennsylvania School of Medicine, published their report online on July 17 in the Journal of Biological Chemistry. In congenital hyperinsulinism (HI), genetic mutations damage the insulin-secreting beta cells in the pancreas. (Science Daily)
Cancer Patients Are Not Given Enough Information, Experts Say Aug 4, 2008
Three common cancers were chosen colorectal, non-small cell lung, and pancreatic cancer. The researchers used data from a study of patients' of experiences treatments (ASPECTS) to examine the extent to which survival gain was discussed when patients were offered palliative chemotherapy. (Science Daily)
Frances M. Jackson Aug 4, 2008
In lieu of flowers memorials may be made to the Pancreatic Cancer Action Network. Online condolences may be left at. (Muscatine Journal, IO)
Call for better chemo counselling Aug 3, 2008
The study focused on 37 patients with terminal colorectal, lung and pancreatic cancer. A researcher interviewed each patient before they saw their oncologist, then recorded the consultation with the health professional where further treatment would have been discussed. (BBC News)
Saturday, Aug. 2, 2008 (59) Aug 3, 2008
FREDERIKA Thomas Joseph Babcock, 64, of Frederika, died at home Tuesday, July 29, of pancreatic cancer; public graveside services 3 p.m. Sunday at New Hampton Cemetery, followed by a celebration of life service at Kolby s Dine and Stein; visitation 4 to 8 p.m. today at Conway-Kolbet Funeral Home, New Hampton, (641) 394-4331; memorials to Pancreatic Cancer Action Network at. WELLSBURG Phyllis Maxine Grobe, 88, of Wellsburg, died Thursday, July 31, at the Presbyterian Village, Ackley; services 10... (Waterloo-Cedar Falls Courier)
Carcinogen worries stick to food packaging Aug 3, 2008
Federal investigators determined in 2005 that PFOA is a "likely carcinogen" and called for expanded testing to study its potential to cause liver, breast, testicular and pancreatic cancer. In 2006, the EPA invited all companies involved with PFOA to join a voluntary "stewardship program" to reduce use and emissions of the chemical by 2010 and eliminate the substance by 2015. (Yahoo News -- Consumer News)
Grant Wood's summer idyl at Clear Lake Aug 3, 2008
Pancreatic cancer was discovered. Grant told Park that he wanted to shut the severity of his illness out of his mind, and they made certain that all the talk was very cheerful and optimistic, Juhl wrote in his book. (Mason City Globe-Gazette, IO)
The genetic testing revolution Aug 3, 2008
Genetic testing is available for breast and ovarian cancers, colorectal cancer, pancreatic cancer and melanoma ... The cost of a comprehensive test for pancreatic cancer or melanoma caused by the same mutated gene is $2,000, Courtney said. (Mason City Globe-Gazette, IO)
Play the hand you're dealt Aug 3, 2008
He gave the 76-minute lecture a year after receiving a death sentence from his doctor: pancreatic cancer. The lecture was later expanded into a best-selling book, titled The Last Lecture. (The Gazette (Montreal))
Obituaries for Saturday, Aug. 2, 2008 Aug 2, 2008
Published - Saturday, August 02, 2008. Richard K. Burley Richard K. Burley, 46, of La Crosse died July 13, 2008. (La Crosse Tribune, WI)
Randy Pausch Aug 1, 2008
We could watch his "Last Lecture" on YouTube, receive the gift he was giving us and reject the idea that it would come at an ultimate price--that Pausch would indeed die one day of pancreatic cancer, as he did on July 25 at the age of 47. "You cannot change the cards you are dealt," he said, "just how you play the hand." With his child's smile and nimble brain and breathtakingly simple instructions tumbling out one after another, Pausch made the infernally complex machine that is modern life... (TIME)
Cancer cluster feared at Qld hospital Aug 1, 2008
The most common was breast cancer but there were also cases of bowel and pancreatic cancer, leukaemia and melanoma. "We really felt that if staff are concerned about it ... the only way to address those concerns was to retain some consultants and conduct a proper and thorough investigation so we can give them a high level of comfort that there isn't a problem," Mr Lizzio said. (Sydney Morning Herald -- Australia)
Eurand Enters Agreement With Daewoong Pharmaceutical Co. Ltd (South Korea) for Once-Daily Extended Release Muscle Relaxant Aug 1, 2008
Eurand completed two phase III clinical trials for EUR-1008 (Zentase), intended for the treatment of Exocrine Pancreatic Insufficiency and as announced on June 18, 2008, received an approvable letter from the FDA for its NDA for this product. Eurand's technology platforms include bioavailability enhancement of poorly soluble drugs, customized release, taste-masking/fast-dissolving formulations and drug conjugation. (Primezone Releases)
ANALYSIS-ImClone bid sparks biotech rally, maybe premature Aug 1, 2008
Fri Aug 1, 2008 8:05am BST. NEW YORK (Reuters) - Bristol Myers Squibb Co's (BMY.N: , , ) bid for longtime cancer-drug partner ImClone Systems Inc (IMCL.O: , , ) on Thursday sparked a biotech rally, but it might be premature to assume a wave of other biotech deals will soon follow. (Reuters)
Hooked Onto Texting? Watch Out For Your Health! Aug 1, 2008
The dream of every woman to have slim and trim figure, from now on, may not just be linked to looking attractive with prefect posture but may also be associated with cutting down on the risk of developing pancreatic cancer. by - June 20, 2008 - 0 comments. (TheMedGuru)
Mutual Funds &Personal Finance Aug 1, 2008
It's even still showing strength in the face of Sit's death on June 24 at age 70 after a courageous battle with pancreatic cancer. The fund currently lists $211 million in assets, a 5. (Investors Business Daily)
Think of how two lives ended (25) Jul 31, 2008
For almost a year, the 47-year-old professor of computer science had been confronting terminal pancreatic cancer. As is often the eerie case with deadly cancers, Pausch felt well for much of the time. (Albany Democrat-Herald, OR)
Teter also runs for his mother Jul 31, 2008
Five months earlier, Marian had been diagnosed with pancreatic cancer and was initially given four months to live. Through the next five months she underwent chemotherapy and radiation therapy. (Dowagiac News, MI)
D2 Lymphadenectomy plus PAND for Gastric Cancer Jul 31, 2008
There were no significant differences between the two groups in the frequencies of anastomotic leakage, pancreatic fistula, abdominal abscess, pneumonia, or death from any cause within 30 days after surgery (the rate of death was 0. 8% in each group). (New England Journal of Medicine)
Business.view: In sickness and in wealth Jul 30, 2008
But it also shows that investors are worried about both the health of Mr Jobs, who underwent successful surgery to tackle pancreatic cancer in 2004, and about Apple s lack of an explicit plan to replace him should he become incapacitated. Apple s experience is a wake-up call to board directors everywhere, who need to sharpen their thinking on executive succession, especially given the febrile state of today s financial markets. (The Economist)
THE JOBS QUESTION: Do investors have right to know about a CEO's illness?... Jul 30, 2008
Steve Jobs health came under scrutiny recently after the chief executives gaunt appearance at the companys developer conference revived memories among observers of his battle with pancreatic cancer in 2004. An analyst subsequently inquired after the CEOs well-being on a conference call. (The Drudge Report)
Swayze back to work Jul 30, 2008
The 55-year-old actor, who was rumored to be dying after he was diagnosed with pancreatic cancer earlier this year, looked tanned and healthy as he arrived on the Chicago set of US TV show 'The Beast. The 'Ghost' star, who was accompanied by his wife Lisa Niemi, laughed and joked with the crew throughout the shoot. (AZCentral -- Entertainment)
Women With Gestational Diabetes At Risk Of Type 2 Diabetes Jul 30, 2008
16, 2007) Pregnancies in Jerusalem in the 1960s and 1970s may hold vital clues about how pancreatic cancer and diabetes are linked. According to new research, women with a history of gestational diabetes had a. (Science Daily)
Angiotensin Receptor Blockers Are Lower Incidence, Progression Of Alzheimer's Disease Jul 30, 2008
15, 2008) Researchers are inching closer to understanding how common blood pressure medications might help prevent the growth and spread of pancreatic cancer. They have found in the laboratory that one type of. (Science Daily)
New Biomarker For Early Cancer Detection? Research Reveals That 'MicroRNA' May Fit The Bill Jul 30, 2008
(June 12, 2008) Researchers have identified a panel of proteins linked to early development of pancreatic cancer in mice that applies also to early stages of the disease in humans -- a breakthrough that brings. (Sep. (Science Daily)
'Sickly' Panic over Jobs' mystery illness. Jul 29, 2008
Many speculated that Jobs, who pulled Apple out of the doldrums in the late '90s and remains the architect of much of its recent success, was suffering from a recurrence of pancreatic cancer, which he had surgery to remove in 2004. CNBC reporter Jim Goldman, who interviewed Jobs at WWDC, wrote: "His handshake was moderate, his hands felt bony and I was taken aback by his extremely narrow face, slight build, and noticeable shoulder bones through his shirt ... these weren't the features of a guy... (The Age, Australia)
Jobs tells paper he is cancer-free Jul 29, 2008
The column followed weeks of speculation about Jobs' health amid concerns in the media the Apple boss could be facing medical problems related to surgery he had years before to treat pancreatic cancer. published by the Times on Saturday (July 26), Jobs reportedly informed in an off-the-record conversation that he had some undisclosed health issues but that "they weren't life-threatening and he doesn't have a recurrence of cancer.". (EETimes)
Randy Pausch Life Teacher Jul 29, 2008
But then there were others when his exuberance physical and spiritual made it easy to convince myself it would never happen, and so I would call up on YouTube and watch it with my children, receive the gift he was giving us and reject the idea that it would come at an ultimate price: that would indeed die one day of pancreatic cancer, as he did this morning, at the age of 47. Related Articles. (Time.com)
Apple's Jobs Doesn't Have Recurrence of Cancer, NYT Reports Jul 28, 2008
July 27 (Bloomberg) -- Chief Executive Officer hasn't experienced a recurrence of his pancreatic cancer, and his recent health issues aren't life-threatening, wrote in his New York Times column yesterday. Nocera wrote that the Apple co-founder telephoned him on July 24 and wouldn't go on the record in explaining what led to his visibly ill appearance when introducing the newest iPhone last month. (Bloomberg)
* World Business Quick Take Jul 28, 2008
In 2004, Jobs, 53, announced he had undergone successful surgery to remove a rare type of pancreatic cancer. Concerns about his health roared back last month, when a thinner-than-usual Jobs introduced the latest iteration of the iPhone in San Francisco. (Taipei Times, Taiwan -- World)
US 'last lecture' academic dies Jul 27, 2008
He died of pancreatic cancer at his home in Chesapeake, Virginia, said Jeffrey Zaslow, the Wall Street Journal writer who co-wrote the book The Last Lecture ... Prof Pausch, who taught computer science at Carnegie Mellon University, Pittsburgh, Pennsylvania, was diagnosed with pancreatic cancer in September 2006. (BBC News -- Americas)
12,000-mile bike ride nears its completion Jul 27, 2008
His mother, Anne Hall, died of pancreatic cancer, in 1996, and just last year his wife, Jane, was diagnosed with breast cancer. Since then, Jane Hall has come through treatment in good health, and has been driving the support van around the country to help her husband. (Lompoc Record, CA)
'Last Lecture' Computer-science Professor Randy Pausch Dies Jul 27, 2008
Randy Pausch, a computer-science professor who became internationally known for his inspiring "Last Lecture," passed away in Chesapeake, Virginia, Friday after losing a battle with pancreatic cancer ... Pausch called the talk "The Last Lecture" because he had recently been told by doctors he had only months to live due to pancreatic cancer that had spread to his liver. (Yahoo News -- Technology)
Apple CEO Jobs' life not in danger: report Jul 27, 2008
In 2004, Jobs, 53, announced he had undergone successful surgery to remove a rare type of pancreatic cancer. Concerns about his health roared back last month, when a thinner-than-usual Jobs introduced the latest iteration of the iPhone at a conference in San Francisco. (Yahoo News -- Technology)
SCRIPPS HOWARD NEWS SERVICE NEWS BUDGET Jul 27, 2008
PAUSCH (Chute, Pittsburgh Post-Gazette) -- PITTSBURGH: Randy Pausch, the Carnegie Mellon University computer-science professor whose final lecture inspired millions, has died of pancreatic cancer. 450. (Scripps Howard News Wire)
Obituaries for Sunday, July 27, 2008 Jul 27, 2008
William Bell Kelley, 69, devoted husband, father, family man and friend, passed away peacefully Thursday, July 17, 2008, surrounded by family and friends at Joanne s House of Hope Hospice in Bonita Springs after a courageous battle with pancreatic cancer. He was born Feb. 28, 1939, in Downer s Grove, Ill. (La Crosse Tribune, WI)
Remembering 'Last Lecture' Author Randy Pausch Jul 27, 2008
Randy Pausch, the charismatic young college professor who chronicled his battle with pancreatic cancer in a remarkable speech widely-known as the "Last Lecture," has died at the age of 47 ... Carnegie Mellon professor, 47, succumbs to pancreatic cancer ... Pausch, a father of three small children with his wife Jai, had been diagnosed with pancreatic cancer -- and given six months to live. (ABC News)
"Last Lecture" Professor Dies at 47 Jul 27, 2008
Pausch was diagnosed with incurable pancreatic cancer in September 2006 ... Pausch lobbied Congress for more federal funding for pancreatic cancer research and appeared on "Oprah" and other TV shows. (Time.com)
Diagnosis a Death Sentence Jul 26, 2008
Pancreatic Cancer Diagnosis Often a Death Sentence ... The author of "The Last Lecture," which became a YouTube sensation, died Thursday night of pancreatic cancer, dedicating his final weeks to increasing public awareness of the almost-always disease ... Most pancreatic cancer cases are asymptomatic, meaning patients rarely exhibit symptoms of an illness. (Fox News)
New Treatment Combination Safe For Pancreatic Cancer Patients Jul 26, 2008
ScienceDaily (June 6, 2008) Treating pancreatic cancer with a combination of chemotherapy, biotherapy and radiotherapy prior to surgery is safe and may be beneficial for patients, according to a University of Pittsburgh Cancer Institute (UPCI) study presented at the 44th annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago ... In a preliminary study, physicians from the Pancreatic Cancer Center of the University of Pittsburgh Medical Center (UPMC) Cancer Centers examined... (Yahoo News -- Cancer)
Steve Jobs tells me, but not investors Jul 26, 2008
His thoughts about death came during a portion of his speech in which he publicly discussed - for the one and only time, so far as I can tell - his brush with pancreatic cancer ... How, after "living with that diagnosis all day," he had a biopsy that showed that his was a rare form of pancreatic cancer, curable with surgery ... In fact, Mr. Jobs first discovered he had an islet cell neuroendocrine tumor - which is both rarer and less deadly than other forms of pancreatic cancer - in October... (International Herald Tribune -- Business)
Author Of Last Lecture Loses Battle With Cancer Jul 26, 2008
Pausch was diagnosed with pancreatic cancer in September 2006 and chronicled his treatment on his Web site. The university says he succumbed this morning at his home in Virginia. (KWTX.com, TX)
CMU professor who inspired millions dies Jul 26, 2008
Dr. Pausch, 47, died yesterday from the pancreatic cancer he had been fighting for nearly two years, leaving behind his wife and three young children ... When Dr. Pausch stepped into McConomy Auditorium at Carnegie Mellon last September, he had been fighting pancreatic cancer -- the deadliest of all malignancies -- for nearly a year, with surgery, radiation and chemotherapy ... " Funeral plans,donations Dr. Pausch's family plans a private funeral in Virginia, and Carnegie Mellon said it would... (Pittsburgh Post-Gazette, PA)