Neural Stem Cells In Mice Affected By Gene Associated With Longevity Nov 6, 2009
Further investigation bolstered their findings when they discovered that the FoxO3 protein regulates the expression of genes involved in quiescence and differentiation in cells. The researchers concluded that FoxO3 may be needed for the stem cells to re-enter a waiting state called quiescence that normally occurs after dividing ... Cells that are unable to enter quiescence are less able to self-renew and may lose their ability to become any of the three nerve cell types. (Science Daily)
Study Supports DNA Repair-blocker Research In Cancer Therapy Aug 21, 2009
All cells progress through a series of phases -- called the cell cycle -- including quiescence, or resting, growth, and cell division. The transition from one phase to the next is regulated by "checkpoint" proteins that, among other things, are designed to prevent damaged, potentially dangerous cells from reproducing. (Science Daily)
Serial Monitoring With ImmuKnow(R) is Useful in the Risk Assessment of Kidney Transplant Recipients May 31, 2009
Based on the results of this study, Dr. Carreno commented, "Pre-transplant baseline readings and serial monitoring with ImmuKnow are crucial for posttransplant risk assessments. Our results suggest that an isolated ImmuKnow test is insufficient to aid in the management of posttransplant recipients." In addition, Dr. Carreno said, "Serial posttransplant ImmuKnow values are useful because patients with 'immunological quiescence' have fewer complications compared to patients with erratic ImmuKnow... (PR Newswire)
Heart Protein Regulates Blood Vessel Maintenance May 15, 2009
ScienceDaily (May 14, 2009) In a study led by Akiko Hata, PhD, of Tufts University School of Medicine, researchers have shown that a protein expressed in the heart, FHL2, inhibits the genes necessary for the quiescence of vascular smooth muscle cells (vSMCs), which line blood vessels. Vascular smooth muscle cells undergo a process in diseases such as atherosclerosis or normal tissue damage caused by balloon angioplasty where they transition between a resting and proliferative state. (Science Daily)
Process controlling T cell growth and production identified May 4, 2009
The description of cell intrinsic regulation of quiescence in normal T cells will provide insights on the pathobiology of lymphoid malignancies. The researchers then immunized mice deficient for ELF4 to test their immune response. (EurekAlert!)
* Lucky to have a job? Mar 28, 2009
Conways Birkbeck colleague, Rob Briner, said he has been surprised at the apparent quiescence of many 21st century employees faced with the prospect of their own redundancy. A lot of people felt safe, and now they feel unsafe, he said. (Taipei Times, Taiwan -- Sports)
