Blocking effects of viral infections may prevent asthma in young children Nov 8, 2007
Severe RSV infections, typified by persistent coughing, wheezing and gasping for breath, send many thousands of children to the hospital each year. To investigate the connection between severe respiratory viral infections and subsequent asthma, the researchers used mice genetically selected to have an asthma susceptibility and infected them with a virus similar to RSV. They found that severe respiratory infections in the mice induced an allergic-type immune response and ultimately caused... (EurekAlert!)
Many Babies Who Suffer From Bronchiolitis Are Inherently Predisposed Oct 20, 2007
6, 2007) For the past four decades, medical science thought it knew how severe RSV infections arose. Scientists blamed an overreaction in the lungs by specific immune-system cells, T lymphocytes (also known. (Science Daily)
Medimmune announces phase 2 safety data for anti-RSV antibody and national RSV surveillance results Oct 5, 2007
Each year, up to 125,000 infants in the U.S. are hospitalized with severe RSV infections, the leading cause of lower respiratory tract infections in infants in the United States. RSV is the most common respiratory infection in infancy or childhood. (EurekAlert!)
RSV Drug Starts Phase Ia Clinical Trials Jul 17, 2007
For example approximately 50 percent of children will experience two RSV infections by the age of two. RSV is the most common cause of bronchiolitis and pneumonia in infants and, according to the World Health Organisation (WHO), is the single most important cause of severe lower respiratory infections in infants and young children. (PR Newswire)
Everybody Loves RNAi Jul 12, 2007
Alnylam has just begun phase 2 clinical trials to treat RSV infections of the respiratory tract. At this pace, it should gain marketing approval -- if it's effective -- in about seven years. (MSNBC -- Business)
Respiratory Syncytial Virus Worse in Kids with Neuromuscular Problems Jun 23, 2007
Simon, at the University of Bonn, and colleagues studied RSV infections in 1541 pediatric patients in 14 German hospitals over a 6-year period. The findings are published in the Pediatric Infectious Disease Journal. (MEDLINEplus)
Weak immune response critical to disease that causes most infant hospitalizations Apr 6, 2007
Instead of being caused by too strong an immune response, theyve shown that severe RSV infections in the lower respiratory tract actually are associated with an inadequate immune reaction a characteristic they share with fatal influenza infections, which were also studied by the group ... Instead of preventing RSV infections, that vaccine actually made them worse, resulting in the deaths of two children in 1967. (EurekAlert!)
Infants at high risk for RSV Feb 6, 2007
Sewell said that RSV infections start out indistinguishable from a common cold ... Sewell said babies who have had RSV infections often have an increased chance of picking up additional lower respiratory tract infections for up to 6 months and may have a predisposition toward developing asthma. (Montana Standard, MT)
MedImmune says Numax reaches study goal Nov 7, 2006
An estimated 125,000 infants each year in the United States are hospitalized with severe RSV infections. About one-half of all infants are infected with RSV during the first year of life. (Washington Business Journal, DC)
