Climate variability and dengue incidence Nov 16, 2009
The unintended consequences of clinical trials regulations Alex McMahon (of the University of Glasgow, United Kingdom) and colleagues critique the International Conference on Harmonisation (ICH) guidance on good clinical practice (GCP), arguing that it is having a disastrous effect on non-commercial randomized clinical trials in Europe. Funding: No specific funding was received for this piece. (EurekAlert!)
Popular Anti-Platelet Therapy Reduces Risk of Cardiovascular Events in Men and Women Nov 16, 2009
Lead investigators of the five double-blinded, randomized placebo-controlled trials shared original study data with authors. Clopidogrel works to disrupt platelet activity and prevents them from clotting and causing heart attacks and strokes. (Science Daily)
Researchers Mobilizing Global Resources to Test New Treatments for Severe H1N1 Infection Nov 15, 2009
A program of accelerated randomized clinical trials aimed at quickly identifying, testing and delivering new treatments. The first group of clinical studies will evaluate inexpensive interventions that are available in both the developed and the developing world. (Science Daily)
Honey May be Best Cough Medicine Nov 15, 2009
According to a 2007 American Medical Association double-blinded randomized study entitled , by Ian M. Paul et al, honey may be more effective than DM in children between the ages of two and eighteen when given 30 minutes before bedtime. Studied 105 children (ages 2-18) with cough at night due to an upper respiratory infection (URI). (Suite101.com)
Fish Oil Supplements Don't Help Depressed Heart Patients Nov 14, 2009
For this study, 122 patients with major depression and coronary heart disease took 50 milligrams of Zoloft a day, then were randomized to receive either 2 grams a day of omega-3 acid ethyl esters or a corn-oil placebo capsule. There was no difference in depression scores before and after 10 weeks of treatment, the researchers found. (MEDLINEplus)
Mood Improves On Low-fat, But Not Low-carb, Diet Plan Nov 13, 2009
D., of Commonwealth Scientific and Industrial Research Organisation-Food and Nutritional Sciences, Adelaide, Australia, and colleagues conducted a randomized clinical trial involving 106 overweight and obese participants who were an average age of 50. Of these, 55 had been randomly assigned to follow a very-low-carbohydrate, high-fat diet and 51 to a high-carbohydrate, low-fat diet for one year. (Science Daily)
Exposure To Several Common Infections Over Time May Be Associated With Risk Of Stroke Nov 13, 2009
"For example, treatment and eradication of these chronic pathogens might mitigate future risk of stroke. Antibiotic therapy directed against C pneumoniae has been tested in randomized controlled trials without evidence of benefit against heart disease. Whether the same holds true for stroke has not yet been established. More studies will be required to further explore infectious burden as a potential modifiable risk factor for stroke.". Journal reference. (Science Daily)
Ventilation Positions Comparable in Lung Syndrome Patients Nov 13, 2009
"Moreover, prone positioning has been advocated as a rescue maneuver for severe hypoxemia, owing to its positive effects on oxygenation, which have been repeatedly documented since its first description in 1976. However, no randomized clinical trial has yet demonstrated a significant reduction in mortality rate associated with prone positioning," wrote Dr. Paolo Taccone and colleagues. Their study, published in the Nov. 11 issue of the Journal of the American Medical Association, included 342... (MEDLINEplus)
Drugs To Treat Anemia In Cancer Patients Linked To Thromboembolism Nov 12, 2009
"This new finding is significant because where the meta-analysis looked at pooled data from randomized clinical trials, this data is from community practice -- real-life clinical settings -- where you can often see things that wouldn't necessarily show-up in a short-term, 12-week study. Additionally, this analysis included data from more than 50,000 patients- including those with more advanced cancer or high-risk status, who therefore might not have been candidates for clinical trials.". Based... (Science Daily)
Revascularization versus Medical Therapy for Renal-Artery Stenosis Nov 12, 2009
Methods In a randomized, unblinded trial, we assigned 806 patients with atherosclerotic renovascular disease either to undergo revascularization in addition to receiving medical therapy or to receive medical therapy alone. The primary outcome was renal function, as measured by the reciprocal of the serum creatinine level (a measure that has a linear relationship with creatinine clearance). (New England Journal of Medicine)
Surgical Masks Vs. N95 Respirators For Preventing Influenza Among Health-care Workers Nov 12, 2009
from McMaster University, Hamilton, Ontario, Canada, and colleagues conducted a randomized controlled trial of 446 nurses in eight Ontario hospitals to compare the surgical mask with the N95 respirator in protecting health care workers against influenza. The nurses were randomized into two groups: 225 were assigned to receive surgical masks and 221 were assigned to receive the fitted N95 respirator which they were to wear when caring for patients with febrile (fever) respiratory illness ... Loeb... (Science Daily)
Minimally Invasive Surgery Shown Safe And Effective Treatment For Rectal Cancer Nov 12, 2009
That fact plus its relatively small sample size, lack of randomization, and relatively short follow-up period all point to the need for large, randomized studies before its findings can be considered definitive. Dr. Milsom reports that his surgical team is now participating in two such studies, one in collaboration with the American College of Surgeons Oncology Group (ACSOG) and the other headed up by Dr. Lee and involving several other U.S. medical centers. (Science Daily)
Getting to the Heart of Dark Chocol... Nov 11, 2009
In his book, The Spectrum, Dr. Ornish, refers to a randomized controlled trial that was published in The Journal of the American Medical Association (JAMA). The JAMA article stated that the study revealed that six grams (or about an ounce) daily of dark chocolate can lower blood pressure. (Suite101.com)
Radiation After Surgery Reduces Chance Of Melanoma Returning Nov 11, 2009
10, 2009) High-risk melanoma patients who are treated with radiation after surgery have a significantly lower risk of their cancer returning to the lymph nodes (19 percent), compared to those patients who do not have radiation therapy (31 percent), according to the first randomized study of its kind presented at the plenary session, November 2, 2009, at the 51st Annual Meeting of the American Society for Radiation Oncology (ASTRO) ... This multicenter, randomized trial examined the effects of... (Science Daily)
Shorter Radiation Course Stops Cancer Growth In High-risk Prostate Cancer Patients Nov 11, 2009
From January 2003 to December 2007, a total of 168 high risk prostate cancer patients were randomized to receive either hypofractionated or conventional schedules of 3D-CRT to the prostate and surrounding area. Patients who received hypofractionated radiation had only 20 sessions of radiation (four weeks of daily radiation therapy treatments), instead of the 40 to 45 (eight to nine weeks of daily treatments) sessions typically required during standard radiation treatment. (Science Daily)
The latest on cholesterol-cancer link Nov 10, 2009
More studies, including randomized controlled trials, are necessary to explain the link between cholesterol and prostate cancer, according to Platz. Jacobs agreed, noting that the findings of the two studies raise important questions. (CNN)
Once-daily INTUNIV (guanfacine) extended release tablets now available in US pharmacies Nov 10, 2009
The first pivotal trial was a phase III, double-blind, parallel-group trial, in which investigators randomized 345 children aged 6 to 17 years to either a placebo or a fixed 2-mg, 3-mg, or 4-mg dose of INTUNIV given once daily during an eight-week period. The second pivotal trial was a phase III, double-blind, parallel-group trial, in which investigators randomized 324 children aged 6 to 17 years to either a placebo or a fixed 1-mg, 2-mg, 3-mg, or 4-mg dose of INTUNIV given once daily during a... (EurekAlert! -- Business News)
Weight Training Boosts Breast Cancer Survivors' Body Image And Intimate Relationship Satisfaction Nov 10, 2009
The new insights come from a randomized controlled trial that tested the impact of twice-weekly weight-lifting for 12 months on survivors' health and emotional status. In the first report from the trial, published in the New England Journal of Medicine in August, Schmitz and colleagues found that lymphedema sufferers who lifted weights were less likely to experience a worsening of their arm-swelling condition. (Science Daily)
Improving cervical cancer screening Nov 10, 2009
Recently published results from a large randomized trial (Canadian Cervical Cancer Screening Trial study group) suggest that human papillomavirus testing followed by Pap smear-based triage for human papillomavirus positive women may be an effective way to screen women for cervical cancer. We determined the potential cost-effectiveness of including human papillomavirus tests for cervical cancer screening for Canada and three provinces: Alberta, Newfoundland and Ontario. (BioMed Central)
Debate continues over diagnostic scans for lung cancer Nov 9, 2009
Since then, three randomized trials of lung cancer screening comparing X-rays with regular care found no difference in mortality between the two groups. Contrary to what one would expect, two of the trials actually reported small increases in death rates among patients who were screened; they had more lung cancer surgery, which carries a significant risk of death. (Boston Globe)
Genmab Announces Start of Ofatumumab Phase III Head to Head Study in DLBCL Nov 9, 2009
Patients in the study will be randomized to receive three cycles of either ofatumumab or rituximab in addition to chemotherapy. After the third treatment cycle patients who obtain a complete or partial response will receive high dose chemotherapy followed by ASCT. The primary endpoint of the study is progression free survival. (Primezone Releases)
Respirator or face mask? Best shield still debated Nov 7, 2009
The only other randomized clinical trial comparing health-care workers' use of respirators and surgical masks was published online in October 2009 in the Journal of the American Medical Association. Canadian researchers reported no difference in influenza rates among nurses using one type of protective device versus the other. (CNN -- Health)
Benefits of Pomegranate Juice Nov 7, 2009
A pilot study from the International Journal of Impotence Research showed, in a randomized, placebo-controlled, double-bind crossover study, that 47% of the men experienced improvement. The researchers believe that the antioxidant effects may be the reason: They prevent free radicals from interrupting the flow of blood to the source. (Suite101.com)
Cause Of Common Chronic Diarrhea Revealed In New Research Nov 7, 2009
6, 2009) A common type of chronic diarrhea may be caused by a hormone deficiency, according to new research published in the November issue of Clinical Gastroenterology and Hepatology. The authors of the paper, from Imperial College London, with collaborators from King's College London and the University of Edinburgh, say their results could help more doctors recognise this type of diarrheal illness, and may lead to the development of more effective tests and treatments to help improve the lives... (Science Daily)
Nicotine Patch Plus Lozenge Appears Best For Smoking Cessation Nov 6, 2009
D., of the University of Wisconsin Center for Tobacco Research and Intervention, Madison, and colleagues conducted a randomized clinical trial of smoking cessation therapies involving 1,504 adults ... A Randomized Placebo-Controlled Clinical Trial of 5 Smoking Cessation Pharmacotherapies. (Science Daily)
Green tea helps fight oral cancer Nov 6, 2009
During the study, 41oral leukoplakia patients were randomized to receive either green tea extract or placebo. "Collecting oral tissue biopsies was essential in that it allowed us to learn that not only did the green tea extract appear to have benefit for some patients, but we pointed to anti-angiogenic effects as a potential mechanism of action," said Dr Anne Tsao, assistant professor in the Department of Thoracic/Head and Neck Medical Oncology, and the studys first author. (India Times, India)
Cancer Patients Want Honesty, Compassion From Their Oncologist Nov 6, 2009
The most significant preference is that more than one-third of female cancer patients (37 percent) prefer to have their hands held by their radiation oncologists during important office visits, compared to 12 percent of men, according to a randomized study presented November 4, 2009, at the 51st Annual Meeting of the American Society for Radiation Oncology (ASTRO) ... The prospective randomized trial took place between June 2006 and March 2008 and involved 508 patients, who underwent radiation... (Science Daily)
'Health-at-every-size' Approach Is Effective: Health-centered Weight Control Method Shows Promise Nov 6, 2009
In a study conducted by researchers from Laval University, Quebec ,144 pre-menopausal, overweight/obese women (48 in the HAES group, 48 in a Social Support (SS) group and 48 in the control group) participated in a randomized controlled trial. Measurements of eating behaviors, appetite sensations, physical activities, metabolic and anthropometric profiles were made at the beginning of the study, at the end of the intervention period, and at 6 months and 1 year post-intervention. (Science Daily)
How Safe Are Popular Reflux Drugs? Nov 6, 2009
Yet there was no evidence from prospective randomized trials to support those cautionary statements, according to Johnson, who is also past president of the American College of Gastroenterology. "It was all retrospective, or subject to potential biases," he said. (MEDLINEplus)
Some vitamins may be harmful Nov 6, 2009
Indeed, an editorial in the March 18, 2009, Journal of the National Cancer Institute said, "The prospects for cancer prevention through micronutrient supplementation have never looked worse. Several large, randomized cancer prevention trials have recently reported no reduced risk from micronutrient supplementation, and the short report by Figueiredo et al. in this issue of the Journal adds to a growing body of evidence that micronutrient supplementation may be harmful." Jane Figueiredo of... (Honolulu Advertiser)
Postmenopausal Women With Higher Testosterone May Have Greater Heart Disease Risk Nov 6, 2009
(May 2, 2007) Increasing the testosterone levels of female cancer survivors using testosterone cream did not improve their libido more than a placebo, according to a randomized controlled clinical trial in the. (July 30, 2008) As testosterone progressively dominates the hormonal milieu during the menopausal transition, the prevalence of metabolic syndrome increases according to a new study by researchers at Rush University. (Science Daily)
On-Pump versus Off-Pump CABG Nov 5, 2009
D., for the Veterans Affairs Randomized On/Off Bypass (ROOBY) Study Group. ABSTRACT. (New England Journal of Medicine)
Treating Depression in Teens Has Lasting Benefits Nov 5, 2009
TADS is a randomized, controlled trial evaluating the effectiveness of three common treatments for adolescents with depression: the antidepressant Prozac (also called fluoxetine); "talk therapy," also called cognitive-behavior therapy (CBT); their combination (Prozac plus CBT), and, where appropriate, management with a placebo pill (used as a control condition). A total of 327 depressed teens who participated in the study received active treatment for 36 weeks and were then followed for 1 year. (MEDLINEplus)
Concurrent Radiotherapy, Chemotherapy Shows Promise In Small Cell Lung Cancer Nov 5, 2009
This study has been adapted by a new randomized intergroup trial (CALGB/RTOG/ECOG/SWOG) that will enroll 700 patients in multiple sites across the country ... 22, 2007) After an initial chemotherapy treatment, radiation may be a better choice than surgery for patients with stage IIIA non-small-cell lung cancer, according to a randomized controlled trial published in. (Science Daily)
ASK DR. H: No basis for copper claim Nov 5, 2009
The first randomized placebo-controlled (where neither the researcher nor the study participant knew whether a copper bracelet or a sham bracelet was being worn) study on the use of copper and magnetic bracelets was published in the Oct. 12 issue of Complementary Therapies in Medicine. The researchers concluded that there was no meaningful difference between the copper bracelet and the sham bracelet in terms of pain, stiffness and physical function. (Atlanta Journal-Constitution -- Health)
Innovation and Comparative-Effectiveness Research in Cardiac Surgery Nov 5, 2009
Coronary-artery bypass grafting (CABG) was pioneered in the 1960s and subsequently shown in a series of randomized studies to extend life and relieve angina in subgroups of patients with severe coronary disease. 1 As a result of these studies, CABG has grown to become the most common surgical procedure in the world. (New England Journal of Medicine)
Green tea shows promise as chemoprevention agent for oral cancer, M. D. Anderson study finds Nov 5, 2009
In the Phase II dose-finding study, 41 M. D. Anderson oral leukoplakia patients were randomized between August 2002 and March 2008 to receive either green tea extract or placebo. Participants took the extract, an oral agent, for three months at one of three doses - 500 per meter squared of body mass (mg/m2); 750 mg/m2 or 1,000 mg/m2 - three times daily. (EurekAlert!)
Heart Healthy Walnuts Nov 4, 2009
National Institutes of Health, Abstract: A walnut diet improves endothelial function in hypercholesterolemic subjects: a randomized crossover trial. Nunea, Ros E., et. (Suite101.com)
MediciNova Announces Initiation of a Phase Ib Clinical Trial for MN-221 in Patients With Stable, Moderate to Severe Chronic Obstructive Pulmonary Disease Nov 4, 2009
This randomized, placebo-controlled, dose escalation Phase Ib clinical trial designed to evaluate the safety of MN-221 for the treatment of COPD exacerbations will involve approximately 48 stable, moderate to severe COPD patients. Each patient will receive a one-hour intravenous infusion of MN-221 at one of three escalating dose levels or placebo. (Primezone Releases)
Radiation After Surgery Lowers Chances of Melanoma Recurrence Nov 4, 2009
"This is the first randomized study that tested the question whether postoperative radiation therapy offered any advantage in terms of loco-regional control to patients with loco-regionally advanced melanoma," said Dr. Nancy Lee, a radiation oncologist at Memorial Sloan-Kettering. "The authors are to be congratulated for finally completing an important study in our field. This is particularly important as [local] recurrence can be devastating and often is difficult to salvage with additional... (MEDLINEplus)
$600K grant to boost weight-loss program Nov 4, 2009
Randomized control trials with volunteers are under way in the PILI project testing weight loss and management with a culturally relevant approach, including diet, physical activity, stress management and behavioral modification ... Randomized control trials with volunteers are under way in the PILI project testing weight loss and management with a culturally relevant approach, including diet, physical activity, stress management and behavioral modification. (Honolulu Star-Bulletin)
Nicotine Patch Plus Lozenge Most Effective Nov 4, 2009
D., of the University of Wisconsin Center for Tobacco Research and Intervention, Madison, and colleagues conducted a randomized clinical trial of smoking cessation therapies involving 1,504 adults. All had smoked at least 10 cigarettes a day during the previous six months and were motivated to quit. (Newsmax)
Study of concurrent radiotherapy, chemotherapy shows promise in small cell lung cancer Nov 4, 2009
This study has been adapted by a new randomized intergroup trial (CALGB/RTOG/ECOG/SWOG) that will enroll 700 patients in multiple sites across the country. This research will compare three radiation dose levels and treatment duration times. (EurekAlert!)
Good adherence to tuberculosis prophylaxis Nov 3, 2009
Adherence to isoniazid prophylaxis among HIV-infected children: a randomized controlled trial comparing two dosing schedules ... We investigated adherence to study medication in a two centre, randomized trial comparing daily to three times a week dosing of isoniazid. (BioMed Central)
World's largest malaria vaccine trial now underway in 7 African countries Nov 3, 2009
i Alonso PL, Sacarlal J, Aponte JJ, et al. Efficacy of the RTS,S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomized controlled trial. The Lancet. (EurekAlert!)
Mortality Rates Reduced Among Children Whose Mothers Received Iron-folic Acid Supplements Nov 3, 2009
The study is a follow-up to a 1999 to 2001 randomized, double-masked trial of the administration of micronutrients during pregnancy to women in the rural southern plains district of Sarlahi, Nepal ... Christian et al. Antenatal and Postnatal Iron Supplementation and Childhood Mortality in Rural Nepal: A Prospective Follow-up in a Randomized, Controlled Community Trial. (Science Daily)
Gamma Knife Treatment For Glioblastomas Shows Promising Results Nov 3, 2009
Given the positive finding from this study, a multi-center Phase III randomized trial is being designed, said Dr. Einstein. Adapted from materials provided by , via , a service of AAAS. Email or share this story. (Science Daily)
The Healthy Steps Study: A randomized controlled trial of a pedometer-based Green Prescription for older adults: Trial protocol Nov 2, 2009
The Healthy Steps study is a 12-month randomized controlled trial comparing the efficacy of a pedometer-based Green Prescription with the conventional time-based Green Prescription in increasing and maintaining physical activity levels in low-active adults over 65 years of age. The Green Prescription interventions involve a primary care physical activity prescription with 3 follow-up telephone counselling sessions delivered by trained physical activity counsellors over 3 months. (BioMed Central)
Room Design Can Enhance Patient Care Nov 2, 2009
The results of this randomized trial, the first of its kind, will appear in the October issue of Health Environments Research and Design Journal (HERD). See also. (Science Daily)
Results from two Canadian studies confirm sustained viral response rates seen in hepatitis C patients treated with PEGETRON(R) Nov 2, 2009
- Canadian POWeR and REDIPEN(R) Programs presented at the American Association for the Study of Liver Diseases Annual Meeting. " These results reinforce the notion that outcomes achieved with PEGETRON across a large number of clinical trials are consistent and could be generalized to real-life clinical practice.(3) The Future of Hepatitis C Therapy In addition to the POWeR and REDIPEN studies, clinical trial data for Schering-Plough's investigational HCV protease inhibitors boceprevir and... (Canada Newswire)
Therapeutic Value of Reishi Nov 1, 2009
(Noguchi M, et al. Randomized clinical trial of an ethanol extract of Ganoderma lucidum in men with lower urinary tract symptoms. Asian J Androl. (Suite101.com)
Progress Made On Group B Streptococcus Vaccine Nov 1, 2009
Dr. Hillier and her colleagues conducted a double-blind, randomized trial of the GBS vaccine that included a total of 650 sexually active, non-pregnant women ages 18 to 40 who were GBS-negative in the vagina and rectum at the beginning of the study. Approximately one-half of the women were in the control group and received a licensed tetanus and diphtheria toxoids (Td) vaccine instead of the GBS vaccine. (Science Daily)
Switching immunosuppressants reduces cancer risk in kidney Nov 1, 2009
Russ added, "This is the first randomized controlled trial to address whether patients treated with mTOR inhibitors after renal transplantation have less skin cancer.". . (EurekAlert!)
Exercise, Diet, Meds: Diabetes Control Keys? Nov 1, 2009
4 pounds) in the first year of the trial, which was maintained during the rest of the randomized phase and throughout the follow-up. During the randomized phase, participants in the diet-and-exercise arm lost a mean of almost 7 kg (15. (ABC News)
Cholesterol Drugs May Help Prevent Flu Deaths Oct 31, 2009
"Statins may have a role in reducing mortality from influenza, but our findings do not justify broader use of statins without confirming these findings in the setting of randomized controlled trials," said study author Dr. Ann R. Thomas, from the Emerging Infections Program at the Oregon Department of Human Services Public Health Division in Portland. "Statins may have a benefit, in conjunction with vaccine and antivirals, in reducing morbidity and mortality associated with influenza, likely due... (MEDLINEplus)
Q&A with Diablo III's Jay Wilson Oct 31, 2009
Not only does this add to the game's replayability -- with about a 20-hour campaign for the normal difficulty, per character -- but add the multiple difficulty levels, co-op play and randomized content, such as dungeons, monsters and items, and you have a lot of game here. Finally, it would be remiss not to mention Blizzard's amazing production values. (USA Today -- Tech)
Psychotherapy Beats Light Treatment for SAD Oct 31, 2009
For the initial study, 69 people with SAD were randomized to receive light therapy, CBT, a combination of the two or neither (they were wait-listed). Six weeks after treatment started, 80 percent of those receiving combination therapy were in remission vs. 50 percent for CBT and the same for light therapy. (MEDLINEplus)
Laying Still Raises Artificial Insemination Success Oct 31, 2009
The women were randomized to lie prone for 15 minutes after insemination or to get up right away. Twenty-seven percent of women who stayed still for 15 minutes became pregnant vs. 18 percent in the other group. (MEDLINEplus)
Global Phase III Study Results Show Eribulin Meets Primary Endpoint of Overall Survival Oct 31, 2009
This global Phase III study, known as "EMBRACE," (Eisai Metastatic Breast Cancer Study Assessing Physician's Choice Versus E7389), was an openlabel, randomized, parallel two-arm, multi-center study of 762 women with locally recurrent or metastatic breast cancer previously treated with at least two and a maximum of five prior chemotherapy regimens, including an anthracycline and a taxane. The patients were treated either with eribulin (administered intravenously over two to five minutes on days 1... (JCN Network, Japan)
Exercise Keeps Dangerous Visceral Fat Away A Year After Weight Loss, Study Finds Oct 30, 2009
29, 2009) A study conducted by exercise physiologists in the University of Alabama at Birmingham (UAB) Department of Human Studies finds that as little as 80 minutes a week of aerobic or resistance training helps not only to prevent weight gain, but also to inhibit a regain of harmful visceral fat one year after weight loss. The study was published online Oct. 8 and will appear in a future print edition of the journal Obesity. (Science Daily)
Using Herbs to Treat ADHD Oct 30, 2009
In a double-blind, randomized, placebo-controlled trial, 36 children with diagnosed attention-deficit/hyperactivity disorder were studied over a 16-week period. Nineteen of the children received an extract of the herb at a dosage of 50 mg twice daily for 12 weeks, and 17 were given a placebo. (Suite101.com)
Diabetes can be delayed with diet, exercise Oct 30, 2009
The findings follow up on a large randomized trial of 3,234 overweight or obese adults with elevated blood sugar. Results of that study, reported in 2001, found a diet and exercise program and support classes helped cut the risk of developing diabetes by 58 percent after three years compared with a placebo group. (MSNBC -- Health)
Research shows Tai Chi exercise reduces knee osteoarthritis pain in the elderly Oct 29, 2009
Article: "Tai Chi Is Effective in Treating Knee Osteoarthritis: A Randomized Controlled Trial." Chenchen Wang, Christopher H. Schmid, Patricia L. Hibberd, Robert Kalish, Ronenn Roubenoff, Ramel Rones, and Timothy McAlindon. Arthritis Care rch; Published Online: October 29, 2009 (DOI:10. (EurekAlert!)
Doctor's Office Design Can Improve Care Oct 29, 2009
He also said more studies are needed to confirm the findings, which came from a randomized trial. For the study, researchers watched 63 pairs of patients and doctors. (KIRO TV, WA)
A Decade Later, Lifestyle Changes Or Metformin Still Lower Type 2 Diabetes Risk Oct 29, 2009
The DPPOS is a continuation of the DPP, a large, randomized trial in 3,234 overweight or obese adults with elevated blood glucose levels. Researchers announced the initial findings of the DPP in 2001, a year earlier than scheduled because results were so clear: after three years, intensive lifestyle changes reduced the development of type 2 diabetes by 58 percent compared with placebo. (Science Daily)
