Spray Reduces Pain In Children Undergoing Intravenous Procedures Jul 2, 2008
The findings from this double-blind, randomized controlled trial have clinical implications, write the researchers ... In a related commentary, Dr. K.J.S. Anand of University of Arkansas for Medical Sciences (Andrea Peel, tel: 501-686-8996 or 501-351-7903, for Dr. Anand) states that the results of two randomized controlled trials published in CMAJ will "likely alter clinical practice and stimulate further research into the use of currently available nonpharmacologic analgesic in children". (Science Daily)
Limit sucrose as painkiller for newborns Jun 30, 2008
Randomized controlled trial ... In this double-blind, randomized controlled trial of 240 newborns at Toronto's Mount Sinai Hospital, researchers found that "sucrose reduced overall pain in newborns when administered before painful medical procedures during the first 2 days after birth." However, "unexpectedly, we did not observe analgesic effects during either intramuscular injection of vitamin K in either group [newborns of diabetic and nondiabetic mothers] or during repeated heel-lancing for... (EurekAlert!)
Safer, More Efficient Medication For Hepatitis B Treatment Found Jun 29, 2008
ScienceDaily (June 28, 2008) Patients with hepatitis B who did not respond to lamivudine therapy had a better virological response after switching to entecavir for a year. Continuing the drug for an additional year led to even more clinical improvement without significant side effects, according to a new study. (Science Daily)
Oral Drug Helps Prevent Clotting After Hip Replacement Jun 25, 2008
Daily dose of rivaroxaban cut risk of venous thromboembolism, study finds. (SOURCE: The Lancet, news release, June 25, 2008). (Health-Finder)
FDA Extends Review Period for Daiichi Sankyo, Lilly Investigative Antiplatelet Drug, Prasugrel Jun 24, 2008
Daiichi-Sankyo/Lilly Alliance. (PRNewsFoto/Eli Lilly and Company) INDIANAPOLIS and TOKYO, IN UNITED STATES. (PR Newswire)
Primary prevention of diabetes mellitus type 2 and cardiovascular diseases using a cognitive behavior program aimed at lifestyle changes in people at risk: design of a randomized controlled trial Jun 24, 2008
Other articles by authors. Related articles/pages. (BioMed Central)
Aerobic Exercise Increases A Blood Protein That May Suppress Appetite Jun 19, 2008
18, 2007) In a new randomized controlled trial, both aerobic and resistance exercise improved glycemic/blood sugar control in people with type 2 diabetes. The greatest improvements came from combined aerobic. (Science Daily)
Radiation May Help When Prostate Cancer Returns Jun 19, 2008
It halved the death rate and might need to be used more often, researchers say. Tuesday, June 17, 2008. (MEDLINEplus)
Non-Surgical Approach Can Treat Lung Cancers Jun 18, 2008
"Our study shows that radiofrequency ablation can be completed successfully in high percentage of patients with small lung tumors. ...The safety profile of the procedure was also acceptable, with no mortality or life-threatening complications associated with it. ... A randomized controlled trial comparing radiofrequency ablation versus standard treatment options is now warranted to prove the clinical benefit of this approach," the researchers wrote. More information. (Health-Finder)
Anti-estrogen Drug Therapy Reduces Risk Of Invasive Breast Cancer In Older Women Jun 17, 2008
The results of the randomized controlled trial will be published in the Journal of the National Cancer Institute. See also. (Science Daily)
St. John's Wort of no help for ADHD symptoms Jun 12, 2008
Hypericum perforatum (St John's Wort) for Attention-Deficit/Hyperactivity Disorder in Children and Adolescents: A Randomized Controlled Trial. Wendy Weber, ND, PhD, MPH, Ann Vander Stoep, PhD, Rachelle L. McCarty, ND, MPH, Noel S. Weiss, MD, DrPH, Joseph Biederman, MD, Jon McClellan, MD. (CTV.ca)
Osteoporosis Drug Helps Prevent Breast Cancer Jun 11, 2008
The results of the randomized controlled trial will be published in the June 10 online issue of the Journal of the National Cancer Institute. Breast cancer is the most common cancer among women. (Newsmax)
Children's Consumption Of Sugar-sweetened Beverages Jun 7, 2008
6, 2008) A recent study published in Pediatrics and led by researchers at Columbia University Mailman School of Public Health found that sugar-sweetened beverages (SSBs) are an increasingly large part of children and teens' diets. Teens who consume SSBs, which include sodas, fruit drinks and punches, and sports drinks, drink an average of 356 calories per day, a significant increase from 10 years earlier. (Science Daily)
Exposure Therapy May Help Prevent Post-traumatic Stress Disorder Jun 7, 2008
D., of the University of New South Wales, Sydney, Australia, and colleagues conducted a randomized controlled trial involving 90 patients who developed acute stress disorder following a non-sexual assault or motor vehicle crash between March 2002 and June 2006 ... Treatment of Acute Stress Disorder: A Randomized Controlled Trial. (Science Daily)
Study findings show infection control intervention helps keep kids in school Jun 2, 2008
Public release date: 2-Jun-2008. Contact: Katie Yates. (EurekAlert!)
Acupuncture reduces pain and dysfunction in head and neck cancer patients after neck dissection Jun 1, 2008
Public release date: 31-May-2008. Contact: Jeanne D'Agostino. (EurekAlert!)
Ibuprofen No Better at Reducing Alzheimer's Risk May 30, 2008
Aspirin, naproxen as effective, but experts don't endorse use of the drugs to combat dementia. Wednesday, May 28, 2008. (MEDLINEplus)
Electroshock: Electroconvulsive Therapy Without Cognitive Side Effects May 29, 2008
In a related editorial Dr. Bernard Lerer, a psychiatrist from Israel not involved in the study, wrote "The paper by Sackeim and colleagues in the current issue of Brain Stimulation shows that use of an ultrabrief stimulus has remarkably few, if any, effects on cognitive function without loss of efficacy. The results provide convincing evidence derived from a randomized controlled trial. ... If supported by additional controlled studies and borne out by clinical experience in the field, these... (Science Daily)
Natural compounds in cocoa tied to blood flow improvements for adults with type 2 diabetes May 27, 2008
Public release date: 26-May-2008. Breakthrough study links cocoa flavanols to positive impact on diabetes-related blood vessel dysfunction. (EurekAlert!)
Latent TB Treatment Saves Time, Money, And Lives May 24, 2008
ScienceDaily (May 23, 2008) A new way to treat patients with latent tuberculosis (TB), who are infected with TB but without symptoms, can effectively treat it in less than half the time and at a lower cost than the current standard treatment, according to researchers who conducted a multi-center, randomized controlled trial. See also. (Science Daily)
Is The Future Of Surgery Painless And Scarless? May 21, 2008
A Prospective Randomized Controlled Trial of NOTES versus Laparoscopic Distal Pancreatectomy ... This prospective, randomized controlled trial compared the efficacy of endoscopic transgastric distal pancreatectomy (ETDP) to laproscopic distal pancreatectomy (LDP). (Science Daily)
New treatment for hepatitis C May 18, 2008
The Hindu News Update Service. The HinduPrint Edition. (Hindu)
Statin Drug Used To Lower Cholesterol Effective For Hepatitis C Treatment, Study Shows May 16, 2008
ScienceDaily (May 15, 2008) Researchers at the OU Health Sciences Center have found a new use for an old drug. Their findings appear online Friday in the American Journal of Gastroenterology. (Science Daily)
'Falls Clinics' Help Cut Elderly Fall Risk May 10, 2008
These findings provide positive support for the effectiveness of the falls clinic approach, and should be further evaluated through a randomized controlled trial, the researchers conclude. SOURCE: Journal of the American Geriatrics Society, April 2008. (MEDLINEplus)
YM BIOSCIENCES ANNOUNCES PRESENTATIONS FOR AEROLEF(TM) AT AMERICAN PAIN SOCIETY ANNUAL MEETING May 5, 2008
The first poster presentation, entitled "A randomized controlled trial demonstrates the efficacy, safety and tolerability of Aerosolized free and Liposome-Encapsulated Fentanyl (AeroLEF(TM)) via pulmonary administration", is scheduled to be presented on Thursday, May 8, 2008 (Abstract #8448, Poster Board number 265). The second poster presentation, entitled "Comparative phase I PK study of Aerosolized free and Liposome-Encapsulated Fentanyl (AeroLEF(TM)) demonstrates rapid and extended plasma... (PR Newswire)
Pill Ingredient Could Prevent Brain Damage After Head Injury May 3, 2008
Journal reference: Improved outcomes from the administration of progesterone for patients with acute severe traumatic brain injury: a randomized controlled trial. Guomin Xiao, Jing Wei, Weiqi Yan, Weimin Wang and Zhenhui Lu. (Science Daily)
Online Intervention Paramount For Reducing HIV In High-risk Population May 2, 2008
As part of the broader study, Rosser has led a group of investigators to develop one of the world's first online HIV risk reduction interventions, called "SexPulse." A randomized controlled trial testing the effects of SexPulse, currently in progress, will be completed later this year. The study results are published online in the American Journal of Public Health. (Science Daily)
Doctors accused of doing illegal stem-cell trials May 2, 2008
Patients in Austria may have been misled. Clinical trials led by Hannes Strasser have come under scrutiny by an Austrian ethics committee. (Nature News Service)
New Anal Cancer Therapy Fails to Improve Outcomes May 2, 2008
In this new, randomized controlled trial, Dr. Jaffer A. Ajani, of the University of Texas M.D. Anderson Cancer Center in Houston, and colleagues compared treatment with fluorouracil plus mitomycin and radiation therapy to treatment with fluorouracil plus cisplatin and radiation therapy. The findings from 644 patients showed a five-year, disease-free survival rate of 60 percent in the mitomycin group and 54 percent in the cisplatin group. (MEDLINEplus)
Romark Announces Presentation of New Data for Nitazoxanide in Chronic Hepatitis C at EASL 2008 Apr 23, 2008
"These data also provide interesting insights into the mechanism of action of nitazoxanide and confirm previous findings related to its safety." The four presentations include: -- An oral presentation, titled, "Randomized Controlled Trial of Nitazoxanide-Peginterferon-Ribavirin, Nitazoxanide-Peginterferon and Peginterferon-Ribavirin in the Treatment of Patients with Chronic Hepatitis C Genotype 4," reported final 24-week post-treatment sustained virologic response (SVR) rates for the company's... (PR Newswire)
Ferring Pharmaceuticals' EUFLEXXA(TM) to Serve as Sponsor for Sprint Force America Masters Track Club Apr 19, 2008
(2) Kirchner M, Marshall D. A double-blind randomized controlled trial comparing alternate forms of high molecular weight hyaluronan for the treatment of osteoarthritis of the knee. Osteoarthritis Cartilage. (Yahoo! Wire -- Entertainment News)
Physical Activity Is Natural Pain Reliever For Arthritis Apr 18, 2008
A total of 346 individuals with self-reported arthritis from 18 sites participated in a randomized controlled trial. The eight-week exercise program consisted of exercise twice weekly for one hour. (Science Daily)
The Mirror Cure for Phantom Pain Apr 17, 2008
That randomized controlled trial included patients with complex regional pain syndrome and showed long-term (six months) improvements that were similar in magnitude to those reported by Chan et al.. If there is a cumulative effect, then resolution of conflict between sensory and visual feedback is unlikely to be the key mechanism. (Scientific American)
Computer Game Helps COPD Patients Breathe Better, Study Shows Apr 17, 2008
17, 2008) Patients with chronic obstructive pulmonary disease (COPD) may gain better control over their breathing and breathe more efficiently by using their breath to play a computer game, according to new research. "COPD is a double-edged sword: the incapacitating lung condition can cause such serious shortness of breath that every-day physical activity, such as walking a flight of stairs, becomes unduly burdensome--and yet one of the few effective symptomatic treatments for COPD is the very... (Science Daily)
Loop Diuretics Linked to Hip Bone Loss in Older Men Apr 16, 2008
Medical News: Loop Diuretics Linked to Hip Bone Loss in Older Men - in Endocrinology, Osteoporosis from MedPage Today. Personalize Your Medical News. (MedPage Today)
Mental Health Cultivated On The Farm Apr 14, 2008
Journal reference: Animal-assisted therapy with farm animals for persons with psychiatric disorders, effects on self-efficacy, coping ability and quality of life: a randomized controlled trial. Bente Berget, ;ivind Ekeberg and Bjarne O Braastad. (Science Daily)
Estrogen Therapy Increases Benign Breast Disease Risk, Study Suggests Apr 10, 2008
9, 2008) Women who took conjugated equine estrogen, a commonly prescribed form of estrogen, had more than twice the risk of developing specific types of benign breast disease as women who took a placebo, according to a randomized controlled trial published online April 8 in the Journal of the National Cancer Institute. See also. (Science Daily)
Two Liver Cancer Treatments Better Than One Apr 10, 2008
Survival time rose with combo therapy for advanced disease, study finds. Tuesday, April 8, 2008. (MEDLINEplus)
Clinical trial that may help patients breathe easier begins at Central DuPage Hospital Apr 2, 2008
Public release date: 1-Apr-2008. Contact: Meghan Oreste. (EurekAlert!)
Postoperative Chemotherapy Does Not Improve Survival In Gastric Cancer Patients, Study Suggests Apr 1, 2008
To test the PELF combination in patients with localized disease, Francesco Di Costanzo, M.D., of the University Hospital Careggi in Florence, Italy, and colleagues in the Italian Oncology Group for Cancer Research conducted a randomized controlled trial in which 258 patients were treated with surgery or surgery followed by chemotherapy ... 22, 2007) After an initial chemotherapy treatment, radiation may be a better choice than surgery for patients with stage IIIA non-small-cell lung cancer,... (Science Daily)
Filter Fails to Improve PCI Outcomes in Acute Coronary Syndromes Mar 31, 2008
The A-F trial is the first randomized controlled trial to evaluate a vascular protection device in patients with NSTEMI acute coronary syndromes. For the study, Dr. Webster and his colleagues recruited 151 patients treated at 14 medical centers in New Zealand, Australia and Canada, randomly assigning them to protection with the FilterWire or to conventional PCI without vascular protection. (PR Newswire)
Watchful Waiting May Be Proper Initial Treatment For Some HPV Infections, Study Suggests Mar 27, 2008
27, 2008) Human papillomavirus (HPV) DNA-based tests are more accurate than cytology (Pap smears) in detecting cervical precancerous lesions, according to data from a randomized controlled trial. HPV. (Science Daily)
Certain Liver Disease Related To Cardiovascular Fitness Mar 26, 2008
Future studies should include a randomized controlled trial of exercise training that can reveal its direct effects on NAFLD histopathology, they suggest. In the meantime, it would appear rational and prudent for healthcare providers to recommend exercise training to improve health-related fitness as an integral role in the care of patients with NAFLD, they conclude. (Science Daily)
'Old blood' may be risky after surgery Mar 20, 2008
Old blood' may be risky after surgery - USATODAY.com. Old blood' may be risky after surgery. (USA Today)
Overweight, Obese Women Improve Quality Of Life With 10 To 30 Minutes Of Exercise Mar 18, 2008
17, 2008) Sedentary, overweight or obese women can improve their quality of life by exercising as little as 10 to 30 minutes a day, researchers reported at the American Heart Association's Conference on Nutrition, Physical Activity and Metabolism. The Dose Response to Exercise in postmenopausal Women (DREW) study, first reported in 2007, was the largest randomized, controlled trial examining the role of exercise in postmenopausal women. (Science Daily)
A Little Exercise Goes A Long Way For Obese Women Mar 16, 2008
Diet Lifestyle Obesity Women's Health. By Mar 15th, 2008 Category. (MedHeadlines)
Older Men With Low Testosterone Face Greater Depression Risk Mar 7, 2008
"A randomized controlled trial is required to determine whether reducing prolonged exposure to low free testosterone is associated with a reduction in prevalence of depression in elderly men," the researchers wrote. "If so, older men with depression may benefit from systematic screening of free testosterone concentration, and testosterone supplementation may contribute to the successful treatment of hypogonadal (with low hormone levels) older men with depression.". (Health-Finder)
New 300mg Loading Dose Tablet for Plavix(R) Receives Positive Opinion From the European Committee for Medicinal Products (CHMP) Mar 5, 2008
CURRENT is the only randomized controlled trial designed to investigate in 14000 patients, whether the use of a clopidogrel 600mg loading dose, followed by an intensified clopidogrel dosing regimen (6 days at 150mg follow by 75mg) yields improved clinical outcomes as compared to clopidogrel 300mg loading dose followed by 75mg in ACS patients managed with an early invasive strategy. The primary endpoint of CURRENT is the reduction of a composite endpoint of cardiovascular death, stroke and... (PR Newswire)
Regular Drinking Raises Blood Pressure, Meta-Analysis Affirms Mar 5, 2008
Personalize Your Medical News. PUTTING BREAKING MEDICAL NEWS INTO PRACTICE Wednesday, March 05, 2008. (MedPage Today)
A whiff of scent wont cure you Mar 4, 2008
But a randomized controlled trial that tested heart rate, blood pressure, stress hormones and immune function showed no significant changes before and after the big sniff. In fact, some of the 56 men and women in the two-year study showed a stronger reaction to distilled water than to either of the identified aromas. (MSNBC -- Health)
Low Testosterone Linked to Depression in Older Men Mar 4, 2008
A randomized controlled trial is required to determine whether reducing prolonged exposure to low free testosterone is associated with a reduction in the prevalence of depression in elderly men, the authors write. If so, older men with depression may benefit from systematic screening of free testosterone concentration, and testosterone supplementation may contribute to the successful treatment of hypogonadal [with low hormone levels] older men with depression. (Newsmax)
Does Gingko Biloba Affect Memory? Mar 2, 2008
Does Gingko Biloba Affect Memory. Does Gingko Biloba Affect Memory. (Science Daily)
Gingko Biloba, Memory Study Brings Surprises Feb 29, 2008
In the first ever randomized controlled trial of gingko biloba and memory using only participants age 85 and older, improved memory is questionable but another finding is even more surprising. In the study of 118 participants, all of whom had no history of memory problems, half took gingo biloba extract three times a day and half took a placebo. (MedHeadlines)
Statins May Cut Pneumonia Deaths Feb 29, 2008
He added that his group is now planning a randomized controlled trial to investigate the benefit of starting statin therapy in patients admitted for pneumonia. SOURCE: European Respiratory Journal, March 2008. (MEDLINEplus)
A Regular Dip In The Pool Could Benefit Fibromyalgia Sufferers Feb 26, 2008
Now, Narc;s Gusi of the Faculty of Sports Sciences, at the University of Extremadura, in C;ceres, Spain and Pablo Tomas-Carus of the Department of Sport and Health at the University of ;vora, Portugal have carried out a randomized controlled trial with a group of 33 female fibromyalgia patients to find an alternative approach ... Cost-utility of an 8-month aquatic training for women with fibromyalgia: a randomized controlled trial. (Science Daily)
The Quality Initiative in Rectal Cancer (QIRC) trial; study protocol of a cluster randomized controlled trial in surgery Feb 16, 2008
We describe a cluster randomized controlled trial that is testing if the above patient outcomes can be improved through a knowledge translation strategy called the Quality Initiative in Rectal Cancer (QIRC) strategy. The strategy is designed to optimize the use of total mesorectal excision techniques. (BioMed Central)
Researchers at Pulmonary Associates to study airway bypass procedure for severe emphysema Feb 12, 2008
The study will be a randomized controlled trial meaning that patients will be randomly assigned to either a treatment or a smaller control group. Both groups will undergo bronchoscopy but only the treatment group will receive the airway bypass procedure. (EurekAlert!)
Dear Mr Garnier Feb 9, 2008
First up: the study triggering the Avandia stories last year was a meta-analysis (), not a randomized controlled trial. Many criticisms have been leveled at this study (see coverage in , ; subscription required). (Nature News Service)
Malaria Vaccine Trials Begin Using 'Chimpanzee Virus' Feb 2, 2008
1, 2004) The results of a randomized controlled trial of a malaria vaccine called ME-TRAP are published this month in PLoS Medicine. "This first field efficacy trial was an important milestone in the ... > Number of stories in archives: 44,032 Find with keyword(s): Enter a keyword or phrase to search ScienceDaily's archives for related news topics, the latest news stories, reference articles, science videos, images, and books. Just In: Spraying viral genes directly through the skin is a new... (Science Daily)
Silymarin does not affect virus activity or ALT levels in Feb 2, 2008
Public release date: 1-Feb-2008. In a survey of patients with chronic hepatitis C who participated in a National Institute of Diabetes and Digestive and Kidney Diseases-sponsored long-term treatment trial for patients who had failed to respond previously to antiviral therapy, approximately 40% acknowledged to interviewers at the time of enrollment that they were currently using or had in the recent past used herbal products for health purposes. (EurekAlert!)
Clot-Busting Drug Offers New Approach to DVT Jan 29, 2008
Injecting directly into clots prevents recurrence and painful side effects, small trial finds. By Steven ReinbergHealthDay Reporter. (Health-Finder)
Large Study Links Folic Acid Supplementation With Reduced Risk Of Preeclampsia During Pregnancy Jan 25, 2008
The researchers have applied for funding to conduct a randomized controlled trial to determine if there is a cause-and-effect relationship between folic acid dose and risk of preeclampsia. Because the current study was observational in nature, it could only reveal associations. (Science Daily)
Early Promising Results In Malaria Vaccine Trial Jan 24, 2008
Journal reference: MA Thera et al. Safety and immunogenicity of an AMA-1 malaria vaccine in Malian adults: Results of a Phase 1 randomized controlled trial ... 1, 2004) The results of a randomized controlled trial of a malaria vaccine called ME-TRAP are published this month in PLoS Medicine. (Science Daily)
Surgery Better Than Stents for Multiple Blockages Jan 24, 2008
Fewer deaths, heart attacks found in 18-month study. By Ed EdelsonHealthDay Reporter. (Health-Finder)
Is Transcranial Magnetic Stimulation A New Treatment Of Bulimia Nervosa? Jan 23, 2008
7, 2007) In the first randomized controlled trial for adolescent bulimia nervosa to be completed in the US, researchers show that mobilizing parents to help an adolescent overcome the disorder can double the. (Nov. (Science Daily)
