The MOTHERS Act: Thalidomide Revisited? May 24, 2008
The MOTHERS Act: Thalidomide Revisited. The MOTHERS Act: Thalidomide Revisited. (PR Newswire)
Treating SSRI-resistant Depression Mar 28, 2008
Papakostas and colleagues compared two strategies for treating symptoms of major depressive disorder that do not respond to treatment with a selective serotonin reuptake inhibitor (SSRI) antidepressant: either switching to a second SSRI or to a non-SSRI antidepressant. Some common SSRI antidepressants are fluoxetine (Prozac), citalopram (Celexa) and sertraline (Zoloft), while examples of a few common non-SSRI antidepressants are venlafaxine (Effexor) and buproprion (Wellbutrin, Zyban). (Science Daily)
Young male sucide rate at a 30 year low say researchers Feb 18, 2008
The second study finds no effect on suicide of the recent restrictions on antidepressant prescribing to children and adolescents in the UK. They analysed three separate sets of data between 1993 and 2006 (SSRI antidepressant prescriptions to 12-19 year olds in the UK, annual deaths from suicide in 12-17 year olds in England and Wales, and hospital admissions for self-harm in 12-17 year olds in England). But they found no evidence of a temporal association between trends in antidepressant... (OnMedica)
Depressed Mice Reveal Critical Chemical Pathway For Treatment Feb 9, 2008
These patients often show resistance to treatment with SSRI antidepressant drugs. Mice with the mutation had 80 percent less serotonin in their brains than normal mice and exhibited behavioral changes that mirror the symptoms of humans with low serotonin. (Science Daily)
Depression and cardiovascular disease Oct 16, 2007
In addition, the Canadian Cardiac Randomized Evaluation of Antidepressant and Psychotherapy Efficacy, a randomized, controlled, 12-week, parallel-group trial (CREATE) (Lesperance et al., 2007), was the first trial specifically designed to evaluate the short-term efficacy and tolerability of 2 depression treatments in patients with CAD: citalopram, a first-line SSRI antidepressant and interpersonal psychotherapy (IPT), a short-term, manual-based psychotherapy focusing on the social context of... (EurekAlert!)
Spectrum Pharmaceuticals' Board of Directors Elected at Annual Stockholders Meeting Jul 21, 2007
-- Was a key part of the commercial launch of the leading anti-fungal agent Diflucan, the number one selling SSRI antidepressant Zoloft, and the novel alpha-blocker Cardura used for benign prostate hypertrophy. -- Responsible for the formation of a strategic alliance between Pfizer and Eisai related to the clinical development and commercialization of Aricept for Alzheimer's disease, the creation of a co-development and co-promotion agreement between Pfizer and Park Davis for Lipitor, and the... (PR Newswire)
Antidepressants safer than believed during pregnancy Jul 1, 2007
Major concerns over depression drugs taken during pregnancy surfaced in the fall of 2005, when GlaxoSmithKline, the maker of the SSRI antidepressant Paxil, found that pregnant women who were on the drug had an increased chance of having babies with holes in their hearts. In their studies, women on the medication had a 1. (abc13.com)
Depression Drugs May Lead to Apathy in the Elderly Mar 21, 2007
NEW YORK (Reuters Health) - Among depressed older adults, use of an SSRI antidepressant like Prozac may lead to apathy, even though it relieves symptoms of depression, clinicians in Canada report ... In the Baycrest Centre for Geriatric Care's Day Hospital Database, the Canadian team identified 384 elderly depressed patients; 160 were treated with an SSRI antidepressant and 224 with a non-SSRI antidepressant. (MEDLINEplus)
Celexa Effective Against Depression with Heart Patients Jan 24, 2007
Explain to interested patients that when depression accompanies coronary artery disease, two SSRI antidepressants, Celexa and Zoloft, now show evidence of efficacy ... One previous trial showed that the SSRI antidepressant Zoloft (sertraline) was effective in this population. (MedPage Today)
Needle stick leaves nurse feeling unsettled about virus Dec 2, 2006
Withdrawal symptoms from an SSRI antidepressant may include lightheadedness, dizziness, anxiety, nausea/vomiting, headache, visual disturbance, insomnia and depressed mood. The decision to temporarily stop your SSRI medication should be based on the procedure planned, its inherent risk of bleeding complications, the severity of your mood disorder and the likelihood you'll suffer withdrawal symptoms. (Atlanta Journal-Constitution -- Health)
Mom's SSRI Use May Raise Risk of Birth Defects Nov 10, 2006
Wednesday, November 8, 2006. NEW YORK (Reuters Health) - The use of selective serotonin reuptake inhibitor (SSRI) antidepressant drugs early in pregnancy seems to moderately raise the risk of congenital malformations in offspring, suggests the results of a Danish population-based cohort study. (MEDLINEplus)
Regular follow-up important during antidepressant treatment Nov 1, 2006
Simon's editorial was prompted by an article in the same journal by Robert D. Gibbons, PhD, and colleagues, reporting that counties with higher rates of SSRI antidepressant use had lower rates of suicide death in children and younger teens. While this finding is consistent with two other recent observational studies, it contradicts data from several other studies, Simon comments. (EurekAlert!)
Pfizer Japan Launches J ZOLOFT Tablets SSRI Antidepressant Jul 11, 2006
Company News Sectors. Japan Corporate News Network. (JCN Network, Japan)
Antidepressants Linked to Suicide Risk in Elderly Jun 16, 2006
However, no increased risk of suicide was observed during the second and subsequent months of SSRI antidepressant treatment. "Several mechanisms may underlie the association between SSRI antidepressants and suicide," Juurlink and colleagues note ... The patients may also develop feelings of restlessness during SSRI antidepressants, "which may increase the risk of suicide.". (MEDLINEplus)
SSRI Antidepressants Have Slashed Suicides, Study Finds Jun 14, 2006
Far from increasing suicide risk, SSRI antidepressants have saved thousands of lives since they became available in the U.S. in the late 1980s, according to findings from a new study ... Prozac was the first SSRI antidepressant to be sold in the U.S. and it is still the most widely prescribed antidepressant. (FOX News)
Late Pregnancy Use Of SSRI Antidepressant Medication May Affect Fetus Feb 10, 2006
Posted: February 9, 2006. A University of California , San Diego (UCSD) School of Medicine collaborative study with Boston University s Slone Epidemiology Center found an increased risk of persistent pulmonary hypertension (PPHN) in newborns of mothers who used certain commonly prescribed antidepressants in late pregnancy. (Science Daily)
Mylan Laboratories and Forest Laboratories Announce Nebivolol Licensing Agreement Jan 12, 2006
About Forest Laboratories Inc. and Its Products Forest Laboratories' ) growing line of products includes: Lexapro(R) (escitalopram oxalate), an SSRI antidepressant indicated for the initial and maintenance treatment of major depressive disorder and for generalized anxiety disorder in adults; Namenda(R) (memantine HCl), an N- methyl-D-aspartate (NMDA)-receptor antagonist indicated for the treatment of moderate to severe Alzheimer's disease; Benicar(R) * (olmesartan medoxomil), an angiotensin... (PR Newswire)
