Delft breakthrough in bioethanol production from agricultural waste Nov 21, 2009
Bioethanol is made by the yeast Saccharomyces cerevisiae from sugars obtained from plant biomass. This microorganism also converts such sugars into ethanol (alcohol) in beer and wine. (EurekAlert!)
Taking Aim at Hard-to-Treat Fungal Infections Nov 20, 2009
The WPI research team led by Reeta Prusty Rao, PhD, assistant professor of biology and biotechnology, developed the new model using the microscopic soil worm Ceanorhaditis elegans (C. elegans) as a test host which is then infected with the fungus Saccharomyces cerevisiae (S. cerevisiae) ... Reeta Prusty Rao et al. A Pathogenesis Assay Using Saccharomyces cerevisiae and Caenorhabditis elegans Reveals Novel Roles for Yeast AP-1, Yap1, and Host Dual Oxidase BLI-3 in Fungal Pathogenesis. (Science Daily)
Genomes Of Biofuel Yeasts Reveal Clues That Could Boost Fuel Ethanol Production Worldwide Nov 7, 2009
Bioethanol is produced from the fermentation of plant material, such as sugar cane and corn, by the yeast Saccharomyces cerevisiae, just as in the production of alcoholic beverages ... Argueso JL, Carazzolle MF, Mieczkowski PA, Duarte FM, Netto OVC, Missawa SK, Galzerani F, Costa GGL, Vidal RO, Noronha MF, Dominska M, Andrietta MGS, Andrietta SR, Cunha AF, LH Gomes, Tavares FCA, Alcarde AR, Dietrich FS, McCusker JH, Petes TD, Pereira GAG. Genome structure of a Saccharomyces cerevisiae strain... (Science Daily)
Horizontal Gene Transfer and Symbio... Nov 4, 2009
This has been seen with fungi, especially Saccharomyces cerevisiae, a yeast, which has picked up a variety of genes from bacterial species. Symbiogenesis Organisms Merge to Form New Species. (Suite101.com)
First Synthetic Cellulosome In Yeast Created Nov 3, 2009
Tsai et al. Functional Assembly of Minicellulosomes on the Saccharomyces cerevisiae Cell Surface for Cellulose Hydrolysis and Ethanol Production. Applied and Environmental Microbiology, 2009; 75 (19): 6087 DOI. (Science Daily)
Validation of reference genes for quantitative expression analysis by real-time RT-PCR in Saccharomyces cerevisiae Oct 30, 2009
The aim of this work was to search for a set of reference genes for reliable gene expression analysis in Saccharomyces cerevisiae. Results. (BioMed Central)
Time warping of evolutionary distant temporal gene expression data based on noise suppression Oct 27, 2009
We aligned and compared the temporal gene expression data in budding (Saccharomyces cerevisiae) and fission (Schizosaccharomyces pombe) yeast, which are separated by more then ~400myr of evolution. We found that the global alignment (time warping) properly matched the duration of cell cycle phases in these distant organisms, which was measured in prior studies. (BioMed Central)
How to identify essential genes from molecular networks? Oct 13, 2009
By simultaneously analyzing 16 different centrality measures on 18 different reconstructed metabolic networks for Saccharomyces cerevisiae, we show that no single centrality measure identifies essential genes from these networks in a statistically significant way; however, the combination of at least 2 centrality measures achieves a reliable prediction of most but not all of the essential genes. No improvement is achieved in the prediction of essential genes when 3 or 4 centrality measures were... (BioMed Central)
Genome Sequence Published For Important Biofuels Yeast Oct 11, 2009
The study also yielded some interesting genetic information about Saccharomyces cerevisiae, the most studied and utilized yeast species. "The paper suggests that industrial yeast strains may have a high rate of evolution, helping them adapt to the stressful conditions of batch fermentation," said Tom Petes, Ph. (Science Daily)
Combined phylogeny and neighborhood analysis of the evolution of the ABC transporters conferring multiple drug resistance in hemiascomycete yeasts Oct 1, 2009
This subfamily of transmembrane transporters has nine known members in Saccharomyces cerevisiae. We have analyzed the complex evolution of the pleiotropic drug resistance proteins (Pdrp) subfamily where gene duplications and deletions occur independently in individual genomes. (BioMed Central)
RNA Interference Found In Budding Yeasts Sep 16, 2009
"For a long time, people thought that budding yeast didn't have RNAi at all because Saccharomyces cerevisiae, which is the model budding yeast, doesn't have RNAi," says Kathleen Xie, an author on the paper and an undergraduate researcher in the lab of Whitehead Member David Bartel. "And this was kind of a pity because we didn't have a budding yeast model organism available for RNAi research.". (Science Daily)
A reliable measure of similarity based on dependency for short time series: an application to gene expression networks. Aug 28, 2009
The results shown here are for an adapted subset of a Saccharomyces cerevisiae gene expression data set with low temporal resolution and poor statistics. The method reveals common transcription factors with a high confidence level and allows the construction of subnetworks with high biological relevance that reveals characteristic features of the processes driving the organism adaptations to specific environmental conditions. (BioMed Central)
Messenger RNA Are Lost In Translation: Study Challenges Current View Aug 26, 2009
Hu et al. Co-translational mRNA decay in Saccharomyces cerevisiae. Nature, 2009; DOI. (Science Daily)
Case Western Reserve University researcher demonstrates that messenger RNA are lost in translation Aug 24, 2009
The study, "Co-translational mRNA decay in Saccharomyces cerevisiae", is published in the latest issue of Nature. "Many genetic diseases are linked to mutations that can cause mis-regulation of RNA destruction so it's important to know the when, where and how the cell normally controls the process of mRNA decay," said Dr. Coller. (EurekAlert!)
Fungus Found In Humans Shown To Be Nimble In Mating Game Aug 17, 2009
The samples are single-celled yeast related to baker s yeast (Saccharomyces cerevisiae), about several microns across. One cell is too small to see with the maked eye, but colonies of thousands of cells can be easily viewed. (Science Daily)
Researchers uncover potential mechanisms to protect against genetic alterations, diseases Aug 7, 2009
To try to better understand why, the researchers examined GCR formation in chromosome regions in yeast (Saccharomyces cerevisiae). Using a modified version of a previously developed test, they compared the rate and features of GCR formation in a chromosome region lacking "at-risk" DNA sequences with that of a region containing DNA duplications, which are more likely to drive rearrangements. (EurekAlert!)
Yeast Cancer Model For Mapping Cancer Genes Aug 3, 2009
(May 9, 2005) Researchers at UCSD have invented a technique that organizes the genetic information contained in the 16 chromosomes of the yeast Saccharomyces cerevisiae into a wiring diagram resembling an. (Sep. (Science Daily)
Calculation of the relative metastabilities of proteins in subcellular compartments of Saccharomyces cerevisiae Jul 18, 2009
Other articles by authors. Related articles/pages. (BioMed Central)
Reviews of microbial gene language published in special issue of Trends in Microbiology Jul 15, 2009
The characterization of genes in C. albicans has also benefited from the transfer of Gene Ontology terms from the extensively studied yeast Saccharomyces cerevisiae. S. cerevisiae is another workhorse of the molecular biology laboratory and Gene Ontology terms have been instrumental in building a system-wide understanding of the biology of this organism. (EurekAlert!)
Microbes plan ahead, predict future events Jun 27, 2009
The two organisms studied in the research, Escherichia coli and fermenting yeast, Saccharomyces cerevisiae, are widely used by humans for very different reasons. E. coli can travel through the human. (MSNBC -- Environment)
Prions :crossing the species barrier May 28, 2009
Prions formed by chimeras of the prion domain of various species fused to the C domain of Saccharomyces cerevisiae exhibit a 'species barrier', a phenomenon first observed in mammals, and often fail to transmit the prion state to chimeras with prion domains of other species. Results. (BioMed Central)
Requirements for E1A dependent transcription in the yeast Saccharomyces cerevisiae. Apr 18, 2009
Requirements for E1A dependent transcription in the yeast Saccharomyces cerevisiae ... When expressed in Saccharomyces cerevisiae, each of these regions of E1A also acts as a strong transcriptional activator. (BioMed Central)
Rhythmic Genomics: The Yeast Metronome And The Walk Of Life Apr 10, 2009
James et al. Repetitive sequence variation and dynamics in the ribosomal DNA array of Saccharomyces cerevisiae as revealed by whole-genome resequencing. Genome Research, 2009; 19 (4): 626 DOI. (Science Daily)
Students display scientific skills Apr 9, 2009
Daniel Inouye whispered, "If I were in his class, I'd flunk. "He's like a professor bing, bing, bing," Inouye said, referring to Liaw's lucid explanation of his complex project: "Bio-Nano Nano Assembly of Enzyme-Bound Gold Nanoparticles Using Glutathione Reductase from Saccharomyces cerevisiae ... "He's like a professor bing, bing, bing," Inouye said, referring to Liaw's lucid explanation of his complex project: "Bio-Nano Nano Assembly of Enzyme-Bound Gold Nanoparticles Using Glutathione... (Honolulu Star-Bulletin)
New High-throughput Screening Technique Makes Probing Puzzling Proteins Possible Apr 6, 2009
21, 2007) Protein three-dimensional structures were predicted for all Saccharomyces cerevisiae domains that were found to have no sequence similarity to any proteins of known. (Jan. (Science Daily)
Robot makes key artificial intelligence step: study Apr 4, 2009
Adam was tasked with studying the genomics of Saccharomyces cerevisiae, a baker's yeast which scientists use to model more complex life forms. The researchers conducted independent experiments that verified the robot's findings. (Sydney Morning Herald -- Technology)
Scientific robot makes discoveries without human help Apr 4, 2009
Named Adam, the robot is the handiwork of researchers--who unveiled their work Thursday-- at Aberystwyth University and the University of Cambridge in the UK. All by itself Adam discovered new functions for a number of genes in Saccharomyces cerevisiae, aka brewer's yeast. Ross King, a computational biologist at Aberystwyth, who leads the project, said that Adam's results were modest, but real. (Xinhuanet, China)
Robot Scientist: First Machine To Make Discovery Apr 3, 2009
The robot has discovered simple but new scientific knowledge about the genomics of the baker's yeast Saccharomyces cerevisiae, an organism that scientists use to model more complex life systems. The researchers have used separate manual experiments to confirm that Adam's hypotheses were both novel and correct. (Science Daily)
Yeast Biology Yields Insights Into Human Knowledge Expansion Mar 22, 2009
By the end of 2007, more than 73,000 gene-gene interactions in baker's yeast (Saccharomyces cerevisiae) had been discovered and documented in some 5,400 publications authored by 11,238 researchers. In the current study, Jianzhi "George" Zhang, an associate professor of ecology and evolutionary biology, and his former graduate student Xionglei He, now at Sun Yat-sen University in Guangzhou, China used a technique known as temporal network analysis to explore the explosive growth of this field of... (Science Daily)
Synthetic Biology Can Help Extend Anti-malaria Drug Effectiveness Mar 12, 2009
In 2006, the collaboration reported the use of synthetic biology techniques to genetically engineer a strain of yeast (Saccharomyces cerevisiae) that was capable of producing high levels of artemisinic acid, the immediate precursor to artemisinin. Given the existence of known, relatively high-yielding chemistry for converting artemisinic acid to artemisinin or any other derivative that might be desired, microbial produced artemisinic acid is a viable source of this potent family of anti-malarial... (Science Daily)
Commercial yeasts upgraded with an enzyme for biofuel production Feb 25, 2009
In industrial fermentation processes, the yeast Saccharomyces cerevisiae is commonly used for ethanol production. Current bioethanol production technologies can use only parts of the plants, namely the storage sugars, like glucose, sucrose or starch. (EurekAlert!)
Calculating gene and protein connections in a Parkinson's disease model Feb 23, 2009
To demonstrate ResponseNet's capabilities, Yeger-Lotem entered the data from screens of 5,500 yeast strains (Saccharomyces cerevisiae). These strains are based on a yeast model that creates large amounts of the protein alpha-synuclein, thereby mimicking the toxic effects of alpha-synuclein accumulation in Parkinson's disease patients' brain cells. (EurekAlert!)
Phylogenetic diversity of stress signaling pathways in fungi Feb 22, 2009
Putative orthologues of functionally defined signalling components in Saccharomyces cerevisiae were identified by performing reciprocal BLASTP searches, and the percent amino acid identities of these orthologues recorded. This revealed that in general, central components of the osmotic, oxidative and cell wall stress signalling pathways are relatively well conserved, whereas the sensors lying upstream and transcriptional regulators lying downstream of these modules have diverged significantly. (BioMed Central)
Biochemists Discover New Biological Mechanism: Transport Factor Divides Protein Synthesis Between Mother And Daughter Cells Feb 11, 2009
The research was conducted using the yeast Saccharomyces cerevisiae (baker s yeast) ... 21, 2007) Protein three-dimensional structures were predicted for all Saccharomyces cerevisiae domains that were found to have no sequence similarity to any proteins of known. (Science Daily)
