Combined Immunodeficiency Associated with DOCK8 Mutations Nov 19, 2009
Most patients had severe atopy with anaphylaxis; several had squamous-cell carcinomas, and one had T-cell lymphoma leukemia. Elevated serum IgE levels, hypereosinophilia, low numbers of T cells and B cells, low serum IgM levels, and variable IgG antibody responses were common. (New England Journal of Medicine)
Affable local chosen for R.I. Hall of Fame Nov 19, 2009
A three-time winner of the Rhode Island State Amateur and among the few to win the state's amateur and open titles, St. Martin was diagnosed in March 2007 with cutaneous T-cell lymphoma, a rare form of cancer that usually presents in the skin but is not a skin cancer. "Like my doctor likes to say, it's rarely fatal," St. Martin said. (The News-Press -- Sports)
Local biotech firm wins OK on cancer drug Nov 7, 2009
The drug, called Istodax, treats a rare skin cancer known as cutaneous T-cell lymphoma, or CTCL. Roughly 20,000 people in the United States have the cancer, which affects the immune system. The drug could be made available in January for some patients, Gloucester chief executive Alan Colowick said yesterday. (Boston Globe)
Ryan Hess is battling cancer, but he’s not alone. He lives in Sahuarita with his wife, Margie, and their children, Hallie and Max. Nov 4, 2009
In June, Hess was diagnosed with a rare and extremely aggressive form of non-Hodgkins lymphoma known as T-cell lymphoma. His treatment has included intensive chemotherapy and a bone marrow transplant. (Green Valley News & Sun, AZ)
Cordner Nelson, 91; cofounded Track & Field News magazine Oct 31, 2009
The cause was T-cell lymphoma, his daughter Rebecca said. Mr. Nelson became interested in the sport not as an athlete but as a teenage spectator, when his father took him and his younger brother, Bert, to track and field events at the 1932 Summer Olympics in Los Angeles. (Boston Globe)
Eisai and TSD Japan Enter into a License and Joint Development Agreement of Denileukin Diftitox in Japan Oct 26, 2009
Denileukin diftitox is a solution for intravenous injection for the treatment of patients with cutaneous T-cell lymphoma (CTCL) whose malignant cells express the CD25 component of the interleukin (IL)-2 receptor (CD25+) ... Cutaneous T-Cell Lymphoma (CTCL). (JCN Network, Japan)
Allos raises $93M in stock offer Oct 14, 2009
Folotyn is designed to help extend the lives of patients who have a rare form of blood cancer called peripheral T-cell lymphoma and for whom other drug treatments have failed. Allos last month received federal Food & Drug Administration to sell the drug. (Denver Business Journal, CO)
People on the Move: Oct. 5 Oct 9, 2009
Dr. Fagerberg joins Micromet from TopoTarget where he was medical director responsible for the pivotal clinical development program for belinostat for the treatment of peripheral T-cell lymphoma. Insurance. (Washington Business Journal, DC)
New Mesothelioma Treatment Options Oct 2, 2009
Currently, vorinostat, trade name Zolinza, is used as a standard treatment against cutaneous T-cell lymphoma. Avastin Angiogenesis Inhibitor. (Suite101.com)
Aprepitant as an Antipruritic Agent? Oct 1, 2009
To the Editor: The S;zary syndrome is a leukemic, cutaneous, epidermotropic T-cell lymphoma. Pruritus, insomnia, and depression impair the quality of life and can lead to suicide. (New England Journal of Medicine)
Allos Therapeutics gets FDA nod for cancer drug Folotyn Oct 1, 2009
The Westminster-based company (NASDAQ-GM: ALTH) can begin marketing the drug, Folotyn, to help extend the lives of patients who have the rare form of blood cancer called peripheral T-cell lymphoma and for whom other drug treatments have failed ... Approval wasn t a surprise, given that no other treatment is authorized specifically for peripheral T-cell lymphoma cases that fall into relapse after other drugs have failed ... Between 5,000 and 6,000 new cases peripheral T-cell lymphoma are... (Denver Business Journal, CO)
Walkers raise money for Jimmy Fund Sep 14, 2009
Trent Kelley, 8, was not able to do the walk last year because he was undergoing an intensive phase of treatment for T-cell lymphoma, so he went in a stroller instead. This year, he was able to walk at least part of the 3-mile trek. (Boston Globe)
Family isn’t fighting cancer alone Sep 10, 2009
In June, Ryan Hess, 29, husband and the father of two small children, Hallie, 6, and Max, 2, was diagnosed with a rare and extremely aggressive form of non-Hodgkins lymphoma known as T-cell lymphoma. After months of intensive and debilitating chemotherapy, Hess was told that his only hope for survival is a bone marrow transplant. (Green Valley News & Sun, AZ)
FDA Panel Backs New Cancer Drug Sep 3, 2009
A spokeswoman for the U.S. Food and Drug Administration said the agency's panel of cancer experts voted 10-4 that the company's drug pralatrexate would likely benefit patients with T-Cell lymphoma ... T-cell lymphoma is a type of cancer that attacks the immune system for which there are currently no FDA approved treatments. (KWTX.com, TX)
FDA Panel Backs Allos Therapeutics' Cancer Drug Sep 3, 2009
A spokeswoman for the Food and Drug Administration said the agency's panel of oncology experts voted 10-4 that the company's drug pralatrexate would likely benefit patients with T-Cell lymphoma ... T-cell lymphoma is a type of cancer that attacks the immune system ... Company studies of the drug showed 27 percent of patients with T-Cell lymphoma responded to treatment, with more than half responding for about three months. (ABC News -- Wire)
A Woman with Fever, Rash, and Lymphadenopathy Aug 27, 2009
Peripheral T-Cell Lymphomas. Angioimmunoblastic T-Cell Lymphoma. (New England Journal of Medicine)
Allos says FDA panel will review drug on Sept. 2 Aug 11, 2009
Pralatrexate is intended as a treatment for T-cell lymphoma that has recurred or not responded to other drugs. T-cell lymphoma is a type of cancer that attacks the immune system. (Yahoo News -- Pharmaceutical Industry News)
Chelmsford resident plunges into fundraiser for cancer awareness Jul 31, 2009
Ken Block founded Lyrics for Life after his 18-year-old brother Jeffrey lost his four-year battle with T-Cell lymphoma. Several organizations, including Camp Sunshine, and , benefit from the money raised by the skydivers. (Chelmsford Independent, MA)
DNA Mutation That Occurs At Beginning Point Of T-cell Lymphoma Identified Jul 1, 2009
ScienceDaily (June 30, 2009) Researchers at the Keck School of Medicine of the University of Southern California (USC) have identified a key mechanism that causes chromosomes within blood cells to break an occurrence that marks the first step in the development of human lymphoma. The study provides researchers with the clearest insight yet into why these breakages called chromosomal translocations occur at a specific points in the chromosome, says principal investigator Michael R. Lieber, M.D.,... (Science Daily)
BioCryst Pharmaceuticals Announces Presentation of Forodesine Data at the 45th Annual Meeting of the American Society of Clinical Oncology May 15, 2009
May 14 /PRNewswire-FirstCall/ -- BioCryst Pharmaceuticals (Nasdaq: ) today announced long-term data from a Phase 2 study of forodesine, the Company's lead oncology compound, in patients with cutaneous T-cell lymphoma (CTCL) ... Some of the factors that could affect the forward-looking statements contained herein include: that the pivotal trial with forodesine in cutaneous T-cell lymphoma (CTCL) may not meet its endpoint; that development and commercialization of forodesine in CTCL may not be... (PR Newswire)
Make-A-Wish makes Stuckey's Wrestlmania dream come true Apr 20, 2009
Landon was diagnosed with T-cell lymphoma last year, and has been undergoing chemotherapy treatments at St. Louis Children s Hospital once every four weeks, according to his mother, Maya Stuckey. He also takes chemo medication. (Mattoon Journal-Gazette, IL)
Cyclacel Pharmaceuticals Announces Suspension of Quarterly Dividend On 6% Convertible Exchangeable Preferred Stock Apr 8, 2009
Sapacitabine (CYC682), a cell cycle modulating nucleoside analog, is in Phase 2 studies for the treatment of acute myeloid leukemia in the elderly, myelodysplastic syndromes, cutaneous T-cell lymphoma and lung cancer. Seliciclib (CYC202 or R-roscovitine), a CDK (cyclin dependent kinase) inhibitor, is in Phase 2 for the treatment of lung cancer and nasopharyngeal cancer. (Primezone Releases)
• Community news Feb 17, 2009
Morgan suffers from T-cell lymphoma and heart disease. Through the leadership of Student Body President Anna Silver her Mom, Lora Silver-Lewis, and the Student Action Council chairpersons, the school took on the project with enthusiasm and purpose. (Burley South Idaho Press, ID)
