Promising pharmaceutical agents emerge as sports doping products Nov 19, 2009
Public release date: 19-Nov-2009. Contact: Dawn Peters. (EurekAlert!)
Probing the Warburg effect Nov 5, 2009
Proteomes were determined from the tandem mass spectrometry (MS/MS) data by searching against the human subset of the UniProt database. Data were analysed using Significance Analysis of Microarrays for ribonucleic acid and Visualize software for proteins. (BioMed Central)
Endogenous melatonin and oxidatively damaged guanine in DNA Oct 18, 2009
8-oxodG and 8-oxoGua were measured using a high-performance liquid chromatography-electrospray ionization tandem mass spectrometry assay. The mother, father, and oldest sampled daughter were used for these analyses. (BioMed Central)
What makes stem cells tick? Aug 7, 2009
The team performed large-scale, phosphoproteomic analyses of hESCs and their differentiated derivatives using multi-dimensional liquid chromatography and tandem mass spectrometry. The researchers then used the phosphoproteomic data as a predictive tool to target a sample of the signaling pathways that were revealed by the phosphorylated proteins in hESCs, with follow-up experiments to confirm the relevance of these phosphoproteins and pathways to the cells. (EurekAlert!)
Newborn screening test saves lives, money Aug 1, 2009
Of these, 23 (21 per cent), were diagnosed using the newer tandem mass spectrometry technology. Only 1 per cent of NSW parents chose not to have their baby screened. (Sydney Morning Herald -- Australia)
New Method Used To Detect Antibiotics In Honey May 13, 2009
Multiclass Analysis of Antibiotic Residues in Honey by Ultraperformance Liquid Chromatography Tandem Mass Spectrometry. Journal of Agricultural and Food Chemistry, 2009; 57 (5): 1760 DOI. (Science Daily)
U.S. States Expand Newborn Screening For Life-threatening Disorders Feb 27, 2009
The recent advent of tandem mass spectrometry provided the means to identify many conditions from one blood spot. In 2000, the March of Dimes recommended criteria for adding screens in an editorial published in Pediatrics and launched its advocacy efforts to require comprehensive newborn screening in every state at a time when most states screened for only four conditions. (Science Daily)
Now, detect 23 illicit drugs in saliva Feb 14, 2009
The saliva is therefore processed and analysed using two combined systems: liquid chromatography (LC), by means of which the molecules searched for are separated, and tandem mass spectrometry (MS/MS), which enables the "unmistakable" identification of the different chemical compounds, said a USC release. The research group pointed out that drug and medicine detection in oral fluids is a non-intrusive technique, in contrast to blood or urine analyses. (India Times, India)
Method For Detecting 23 Drugs And Medicines In Saliva Developed Feb 14, 2009
The saliva is therefore processed and analysed using two combined systems: liquid chromatography (LC), by means of which the molecules searched for are separated, and tandem mass spectrometry (MS/MS), which enables the "unmistakable" identification of the different chemical compounds ... Concheiro et al. Determination of illicit and medicinal drugs and their metabolites in oral fluid and preserved oral fluid by liquid chromatography tandem mass spectrometry. (Science Daily)
