President Bush Presents 2007 National Medals of Science and Technology and Innovation Oct 3, 2008
The 2007 National Medal of Technology and Innovation to Roscoe O. Brady, for his discovery of the enzymatic defects and hereditary metabolic disorders such as Gaucher disease, Neimann-Pick disease, Fabry disease and Tay-Sachs disease, devising widely used genetic counseling procedures and the development of highly effective enzyme replacement therapy that provided the foundation of patient treatment; and for stimulating the creation of and fostering the success of many biotechnology companies... (White House News Releases)
Battle against nerves Oct 3, 2008
Albany Democrat Herald: Healthy Living. Web Search powered by YAHOO. (Albany Democrat-Herald, OR)
Battle against nerves: Neurofibromatosis can leave some sufferers with bumps where tumors attack nerves Aug 27, 2008
Lancaster and Leaf are among an estimated 100,000 Americans with NF. According to the Children s Tumor Foundation, an advocacy group, this makes the condition more prevalent than cystic fibrosis, hereditary muscular dystrophy, Huntington s disease and Tay-Sachs disease combined. There is no cure for any of the three subtypes of NF. But surgeons can remove tumors when they become painful or threaten normal bodily functions, such as vision and movement. (Racine Journal Times, WI)
Isaiah's family knows time is precious Mar 2, 2008
Later, the ophthalmologist would tell them he saw what no eye doctor ever wishes to see: cherry red spots on the retina, a tell-tale sign of a progressive, fatal genetic disorder that affects the neurological system, called Tay-Sachs disease. What is Tay-Sachs disease. (The Examiner)
Firm proves its stem cell work won't destroy embryos Jan 12, 2008
For more than a decade, clinics have also extracted single cells from the very early embryo when clients want them screened for genetic illnesses such as cystic fibrosis and Tay-Sachs disease. If the single cell tests negative for the disorder, the remaining embryo is implanted. (San Francisco Chronicle)
Get the backstory on genetic diseases Nov 29, 2007
For example, thalassemias are more likely to appear in people of Mediterranean origin, sickle-cell anemia in those of African descent, and Tay-Sachs disease in the Ashkenazi Jewish population. The genetic component of some diseases, such as breast cancer, has been well-catalogued and publicized in the media. (Daily Iowan, IA)
One Shot Of Gene Therapy Spreads Through Brain In Animal Study Oct 11, 2007
If these results in animals can be realized in people, researchers may have a potential method for gene therapy to treat a host of rare but devastating congenital human neurological disorders, such as Tay-Sachs disease ... Other examples of lysosomal storage diseases are Tay-Sachs disease, Hunter disease and Pompe disease. (Science Daily)
Researchers discover new strategies for antibiotic resistance Aug 30, 2007
LA BioMed researchers have invented the modern cholesterol test, the thyroid deficiency test and a test to determine the carriers of Tay-Sachs disease, an inherited fatal disorder. One of the institutes researchers also developed the paramedic model for emergency care, setting a precedent that transformed emergency medical services and became the basis for training paramedics across the country. (EurekAlert!)
Cougars do it the hard way Jul 24, 2007
Rochman is leaving softball so he'll have more time to devote to his vineyard in Makanda and raise money to combat Tay-Sachs Disease. His 2 1/2-year-old granddaughter is suffering from the disease. (Pekin Times, IL)
Part 2: Baby-making at a crossroads Jun 14, 2007
Baby-making at a crossroads - BabyQuest - MSNBC.com. Baby-making at a crossroads. (MSNBC -- Health)
Monkey genes help us see what makes us human Apr 13, 2007
Jumping genes can cause inherited high cholesterol, also called familial hypercholesterolemia, breast cancer, hemophilia, and Tay-Sachs disease. "Who cares if a macaque has hypercholesterolemia, right? What we do care about is, hey, we have got these things in our own genomes that are constantly causing new mutations. Why are they doing it and how do we stop them?" Batzer asked. (Scientific American)
Human stem cells stalled brain disease in mice Mar 14, 2007
It is similar to Tay-Sachs disease, and there is no treatment for either Tay-Sachs or Sandhoff. The use of human embryonic stem cells is controversial because some people believe it is wrong to destroy human embryos in experiments. (MSNBC -- Health)
Mouse tests show stem cells treat brain disease Mar 12, 2007
It is similar to Tay Sachs disease, and there is no treatment for either Tay-Sachs or Sandhoff. MORE SCIENCE NEWS. (Scientific American)
Study on mice is successful, Burnham says Mar 12, 2007
Children with Sandhoff, a form of Tay-Sachs disease, are deficient in an enzyme that helps the body metabolize lipids, a fatty material. A buildup of lipids destroys brain cells that control and coordinate body movement and leads to the deterioration of the brain and spinal cord. (San Diego Union-Tribune -- Business)
Stem cells act through multiple mechanisms to benefit mice with neurodegenerative disease Mar 12, 2007
The mouse used here has mutation in a gene that makes the housekeeping enzyme hexosaminidase ("hex") deficient and, therefore, has Sandhoff's Disease, a lethal genetic disease related to Tay-Sachs Disease. When stem cells were implanted -- at simply one time point -- into brains of newborn Sandhoff mice, the onset of symptoms was delayed, well-being and motor function was preserved, and lifespan was extended by >70. (EurekAlert!)
/R E P E A T/ - A common, but poorly understood disorder stigmatizes and isolates patients - Raises awareness about Neurofibromatosis Feb 9, 2007
Despite the fact that this genetic disorder is as common as cystic fibrosis and more common than muscular dystrophy, Huntington's Disease and Tay-Sachs disease combined, the general public knows little about NF. It is estimated that NF1 occurs in one in every 3,000 births and NF2 occurs in one in every 40,000 births. L'Association de la Neurofibromatose du Qu;bec and The Montreal Children's Hospital want to shed some light on neurofibromatosis. (Canada Newswire)
Let Me Live Death sentence for baby boy Feb 9, 2007
Dylan Dicks, who is just eight months old, has been diagnosed with the fatal Tay-Sachs disease ... Tay-Sachs disease is a genetic disorder that causes destruction of nerve cells and the spinal chord, eventually leading to blindness, paralysis and death. (Sky News)
Ethnic Differences Traced to Variable Gene Expression Jan 11, 2007
Tay-Sachs disease seems to favor Jews of Eastern European descent. Cystic fibrosis has an affinity for Caucasians. (Scientific American)
Genetic expression speaks as loudly as gene type Jan 8, 2007
Cystic fibrosis disproportionately affects Caucasians, for example, and Tay-Sachs disease tends to be more prevalent among Ashkenazi Jews, French Canadians, and other groups. "What's relevant to me is what light this might shed on medical differences," Spielman says. (Nature News Service)
