ASGE encourages patients to see a physician if they experience symptoms suggestive of GERD Jan 26, 2008
This is due to progressive damage to the esophagus, resulting in inflammation, ulceration and possible scarring with narrowing. In addition, these symptoms may be indicative of esophageal cancer. (EurekAlert!)
Leishmania donovani in Indian Mucosal Leishmaniasis Jan 17, 2008
To the Editor: A 62-year-old man from Chamoli District of Uttaranchal, north India, had a 2-year history of a fleshy, polypoid swelling with superficial ulceration on the mucosal aspect of the lower lip, lower gum, floor of the mouth, and palate, without involvement of the skin (Figure 1A and 1B). He did not have a history of kala-azar. (New England Journal of Medicine)
Pet Talk: February is pet dental month Jan 10, 2008
Other potential areas of concern include bleeding from the gums or any ulceration in the mouth. In addition to using your eyes, your nose can be an important tool as well. (Truman Democrat, AR)
A Woman with Painful, Ulcerated Skin Lesions Dec 13, 2007
Erythematous Nodules and Plaques with Ulceration. Mycosis Fungoides. (New England Journal of Medicine)
New Therapeutic Targets In The Treatment Of Ulcerative Colitis Nov 29, 2007
The over expressed MMP-1 excessively degrades the extracellular matrix, and subsequently damages the colonic mucosa and causes ulceration and inflammatory changes in ulcerative colitis, and the over expressed TNF-alpha directly damages the colon mucosa. MP-1 and TNF-alpha proteins have the so-called 'synergistic action. (Science Daily)
Narrow band imaging colonoscopy identifies flat dysplastic lesions in ulcerative colitis patients Nov 19, 2007
The disease is marked by inflammation and ulceration of the colon mucosa, or innermost lining. Because the inflammation makes the colon empty frequently, symptoms typically include diarrhea (sometimes bloody) and often crampy abdominal pain. (EurekAlert!)
Most Diabetics Risk Serious Foot Problems By Wearing The Wrong-sized Shoes Nov 15, 2007
She says that ulceration can have serious implications for patients and health services, including impaired quality of life, increased amputation risk and even elevated death rates. And the World Health Organization has said that the number of people suffering from diabetes could double to 366 million by 2030 and that 80 per cent of diabetic foot amputations could be prevented. (Science Daily)
Almost Two-thirds of Diabetics Risk Amputation Nov 14, 2007
She says that ulceration can have serious implications for patients and health services, including impaired quality of life, increased amputation risk and even elevated death rates. The United Nations, which passed a landmark resolution in December 2006 recognising diabetes as a chronic, debilitating and costly disease, has designated World Diabetes Day as an official United Nations Day for the first time in 2007. (Newsmax)
Many Leg Ulcer Patients Do Not Adhere to Treatment Nov 1, 2007
"In 70 percent of all patients with leg ulcers, ulceration is caused by venous insufficiency," Dr. Maud M. Heinen and colleagues write in the Archives of Dermatology. "Physical activity and adherence to compression therapy are two vital factors in decreasing wound healing time and preventing wound recurrence.". (MEDLINEplus)
The largest colonic lipoma to date Oct 27, 2007
5 cm yellowish polypoid lesion with numerous areas of ulceration on its surface was seen arising from the descending colon. The lesion almost obstructed the whole lumen, and resulted in dilatation of the proximal colon. (EurekAlert!)
Is There Any Alternative To Control Multisteps Of Ulcers? Oct 25, 2007
Anti-ulcer alternatives are preferred by ulcer patients over allopathic drugs, which can have severe side effects, and to replace the multitude of drugs blocking the multiple steps of ulceration, thus lowering the drug burden on ulcer patients ... 4) normalization of antioxidant enzymes which necessitate the management of oxidative stress generated during gastric ulceration and ... The identified polysaccharide also exhibited potent antioxidant activity, including free radical scavenging, DNA... (Science Daily)
Voltaren Gel receives FDA approval as first topical prescription treatment for osteoarthritis pain Oct 23, 2007
NSAIDs cause an increased risk of serious gastrointestinal adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. The use of Voltaren Gel is contraindicated in patients with a known hypersensitivity to diclofenac. (EurekAlert! -- Business News)
Chemical accident forces evacuation Oct 17, 2007
According to the U.S. Environmental Protection Agency, vapors from hydrochloric acid can cause coughing, hoarseness, inflammation and ulceration of the respiratory tract, chest pain and a fluid buildup in the lungs that could result in death in humans. Fire Chief Scott Wellman said the EPA, the Michigan Occupational Safety and Health Administration and the Coast Guard were notified, and Community Emergency Response Team groups went house to house. (The News-Herald)
Risks And Health-care Costs Of Common Pain Killers Underestimated Oct 17, 2007
Serious gastrointestinal complications such as bleeding, ulceration and perforation can occur with or without warning symptoms in people who take NSAIDS (non-steroidal anti-inflammatory drugs. Ulcers and gastrointestinal bleeding are serious health problems in the United States. (Science Daily)
Be Aware, Be ALIVE Oct 17, 2007
Signs of breast cancer:* Painless lump in the breast * Dimpling of skin over breast * Change in contour over the breast * Rash or ulcer over the nipple * Indrawing of the nipple * Blood stained discharge through the nipple * Ulceration (erosion) of the nipple * Lump or fullness in the armpit * Arm swelling. If any of these is found in the breast self examination, consult your docto immediately. (Pune Newsline)
Clinical studies show REMICADE reduces incidence of bowel surgeries in ulcerative colitis patients Oct 16, 2007
UC is a chronic inflammatory bowel disease affecting nearly 500,000 people in the U.S. The disease is characterized by inflammation and ulceration of the colonic mucosa, or innermost lining of the intestine, which causes bloody stools and severe diarrhea. Tiny open sores, or ulcers, form on the surface of the intestinal lining where they bleed and produce pus and mucus. (EurekAlert!)
Six patients treated for C diff Oct 13, 2007
C diff ranges from a mild diarrhoea to a very severe illness with ulceration and bleeding from the colon and, at worst, perforation of the intestine leading to peritonitis. It is found in about one in 50 healthy adults, who carry the bug without it causing any problems. (BBC News -- UK)
Superbug deaths 'a scandal' Oct 11, 2007
C difficile is a virulent strain of bacteria, which can cause symptoms ranging from mild diarrhoea to severe illness with ulceration and bleeding from the colon. The infection can be life threatening in older patients - more than 80% of cases are reported in people aged over 65. (Guardian Unlimited -- UK)
Q&A: C difficile Oct 11, 2007
C difficile symptoms range from mild diarrhoea to severe illness with ulceration and bleeding from the colon. It can lead to perforation of the intestine, causing peritonitis - a serious infection or inflammation of part of the thin membrane that covers the intestinal tract and abdominal organs. (Guardian Unlimited)
Breast health and cancer prevention tips for women and men Oct 3, 2007
An obvious mass and changes in the skin or nipple such as itching, reddening, thickening, ulceration, or retraction are causes for concern, according to Dr. Goulet. Other symptoms include. (News-Medical.net)
UK Government Declares Bluetongue Outbreak Sep 29, 2007
-- Eye, nasal discharge -- Drooling resulting from ulcerations in the mouth -- Fever -- Swelling of the neck, head and mouth -- The animal has a limp (lameness) -- Hemorrhages into or under the skin -- Inflammation at the coronary band (junction of the skin and the horn of the foot) -- Difficulty breathing -- Sheep mortality in a flock may reach 70 ... -- Nasal discharge -- Swelling around the neck and the head -- Runny eyes (conjunctivitis) -- Swelling of the mouth -- Ulceration in the mouth --... (Medical News Today)
Midge cure?Scientists to study spread of the bluetongue virus Sep 26, 2007
Lameness can follow quickly as can inflammation and ulceration of the mucous membrane of the mouth, nose and eyes. Respiratory problems and an inability to swallow are also features of the disease, although discoloration and swelling of the tongue is said to be relatively rare. (BBC News -- Science)
A doctor's busy day Sep 23, 2007
In addition to any number of cancers, Lund explained, smokers can develop Buerger s disease, which causes inflammation in the extremities and sometimes ulceration and gangrene. Eventually, portions of a person s hands and feet may be amputated. (Coos Bay-North Bend The World, OR)
EpiStem Successfully Complete First Year of Mucositis Tests for NIH Biodefence Programme Sep 20, 2007
Dr Tom MacVittie, who co-ordinates the programme at the University of Maryland School of Medicine said: "Gastrointestinal acute radiation syndrome (GI-ARS) is a massive, currently untreatable, problem following high-dose radiation exposure. Agents that mitigate these effects could reduce sickness and hopefully prevent fatalities. The tests performed by EpiStem are also likely to identify agents with oncology supportive care applications - agents that will reduce the severe ulceration and... (PR Newswire)
OHSU seeks spider bite info. Sep 12, 2007
Evidence directly linking spider bites to ulceration or infection is thin, so say OHSU researchers ... There isn t a single documented case of actually seeing a hobo spider bite a human that resulted in ulceration, said Dr. Rob Hendrickson, the study s principal investigator ... Hobo spiders have been presumed to be the only spider in the Northwest capable of causing ulceration. (Coos Bay-North Bend The World, OR)
Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find Sep 3, 2007
Injections of mast cells helped reduce the ear swelling and prevent the ulceration. "All you have to do to cure the mice of this problem is put the mast cells back in," Galli said. (EurekAlert!)
Notes: Chulk has circulatory disease Aug 29, 2007
If untreated, the illness can lead to skin ulceration and gangrene of the fingers and toes. Groeschner pointed out that tobacco use is one of the main causes of Buerger's Disease. (MLB.com -- San Francisco Giants)
FACTBOX-Some facts on female circumcision Aug 20, 2007
-- Immediate complications include severe pain, shock, haemorrhage, urine retention, ulceration of the genital region and injury to adjacent tissue. Haemorrhage and infection can cause death. (AlertNet)
Skin Examination and Biopsy Jul 27, 2007
These include an increase in size, change in colour, texture and borders and bleeding or ulceration of lesions. Their presence may prompt a recommendation for a skin biopsy. (Suite101.com)
Horizon Therapeutics raises $30M Jul 24, 2007
The drug is meant to relieve pain with lower risk of gastric ulceration, and it is now in late stage clinical testing. Horizon has also combined the pain drug naproxen with famotidine in its drug candidate HZT-602, for which it has just filed an investigational new drug application with regulators. (San Jose Business Journal)
Warm months increase deadly seawater bacteria Jul 9, 2007
It can also cause an infection of the skin when open wounds are exposed to warm seawater; these infections may lead to skin breakdown and ulceration. People with weak immune systems are at higher risk for invasion of the organism into the bloodstream and potentially fatal complications. (Daytona Beach News Journal)
Experts warn on diabetes epidemic Jul 9, 2007
"If they do get some of the complications associated with diabetes such as blindness, ulceration of their legs, heart disease, kidney diease, then these are all going to have an extensive effect on health budgets," she warned. Tags. (ABC Online)
The Causative Agent of Amoebiasis Jun 27, 2007
Most infections are asymptomatic, but some strains of E. histolytica can invade the gut wall, causing severe ulceration and amoebic dysentery characterized by bloody stools (Cox, 2002). If the parasites gain access to damaged blood vessels, they may be carried to extraintestinal parts anywhere in the body, the most important of which is the liver, where the amoebae cause hepatic amoebiasis (Tanyuksel and Petri, 2003). (Suite101.com)
Crohn's disease: 'I won't let this illness control me' Jun 20, 2007
Inflammation and ulceration occurs, causing the intestinal wall to become swollen. The result is abdominal pain, narrowing of the bowel (stricture), loss of appetite, diarrhoea and fatigue; all symptoms I had been experiencing for at least a year prior to my diagnosis. (Independent)
Three Studies Suggest Abbott's HUMIRA(R) (adalimumab) May Improve Work Productivity in Patients with Rheumatoid Arthritis Jun 15, 2007
One Groundbreaking Study Showed 11 Percent Fewer RA Patients Reported Job Loss When Treated With HUMIRA Combination Therapy Compared to Methotrexate Alone BARCELONA, Spain, June 15 /PRNewswire-FirstCall/ -- Rheumatoid arthritis (RA) is one of the most common causes of disability in the Western world. New data released today show that rheumatoid arthritis (RA) patients treated with Abbott's HUMIRA(R) (adalimumab) stayed working longer, had fewer absences and reported greater improvements in work... (PR Newswire)
Company recalls contact lens solution May 28, 2007
Acanthamoeba keratitis can produce corneal ulceration and cause severe loss of vision and even blindness. Persistent redness and pain in the eye are among the signs and symptoms. (The Star Online, Malaysia)
Over-the-counter addicts on more than 70 pills a day May 5, 2007
I was addicted to Nurofen Plus for years - I only stopped when I ended up in hospital having had a third of my stomach cut out due to ulceration. One becomes trapped in the spiral "I'll stop tomorrow... Just one more pack..." I was having to go to different pharmacies all over the Wirral to avoid being challenged by the Pharmacist. (Daily Mail)
Two-year data for Angiotech's Vascular Wrap(TM) Paclitaxel-Eluting Mesh to be presented at European vascular symposium Apr 26, 2007
The disease progresses in the lower extremities to critical limb ischemia (CLI), characterized by leg pain at rest, skin ulceration, gangrene, and ultimately amputation. Among patients diagnosed with CLI, 25% may require amputation within a year. (PR Newswire)
Additional Genetic Risk Factors For Crohn's Disease Identified Apr 17, 2007
Serious symptoms can include ulceration, bleeding, the development of fistulas -- openings from affected areas into other organs -- or intestinal blockage. About half a million people in the U.S.are affected by Crohn's, and another half-million have a related condition called ulcerative colitis. (Science Daily)
Survival rate with melanoma has improved Apr 7, 2007
The investigators' analysis showed that tumor thickness, ulceration, age, gender, anatomical site, and period of primary diagnosis independently predicted overall survival. "Interestingly, we found that the survival of patients diagnosed since 1990 seemed to have improved beyond the effects of early diagnosis," Garbe's team comments. (Scientific American)
New Treatment Vacuums Away Blood Clots: Prevents Disability Mar 22, 2007
This condition is characterized by chronic leg pain and swelling which can lead to skin thickening and ulceration. Post-thrombotic syndrome is a common complication of DVT that is under-recognized and potentially preventable if we are able to dissolve the clots early, before permanent damage to the vein occurs, says Garcia. (Science Daily)
Aids: Be cautious with circumcision Mar 9, 2007
Circumcised men, though, had a 50-percent lower rate of genital ulceration. The next step is to see whether that picture changes over the longer term. (iAfrica.com)
Ibuprofen best for children's injury pain Mar 6, 2007
Ibuprofen best for children's injury pain. Last Updated: Mar 5, 2007 - 2:32:26 PM. (Food Consumer)
New Nonsurgical Treatment for Deep Vein Thrombosis (DVT) Vacuums Away Damaging Blood Clots and Restores Blood Flow in the Leg Mar 6, 2007
This condition is characterized by chronic leg pain and swelling which can lead to skin thickening and ulceration. "Post-thrombotic syndrome is a common complication of DVT that is under- recognized and potentially preventable if we are able to dissolve the clots early, before permanent damage to the vein occurs," says Garcia. (PR Newswire)
STI: Awareness as prevention Feb 28, 2007
Granuloma inguinale: A bacterial infection causing ulceration and often severe scarring of the genitalia. Early diagnosis and antibiotic treatment prevents disfiguring scarring. (Jakarta Post, Indonesia -- Features)
'Perfectionism' bowel pain link Feb 26, 2007
Such infections cause inflammation and ulceration in the bowel and can cause severe vomiting and rectal bleeding. Not hypochondriacs. (BBC News)
Limping Sheep Strike Fear in Shepherds Feb 23, 2007
In more severe cases, there'll be erosion and ulceration of the skin. Onstott warns against any conditions that soften or abrade interdigital skin, such as well long pasture, muddy paddocks and congregating areas, wet bedding in warm barns and grazing in stiff stubble. (Agri-View, WI)
Breast Cancer Staging Feb 11, 2007
T4b presence of edema, ulceration or skin nodules. T4c both T4a and T4b. (Suite101.com)
Hyperbaric Chambers in Capital Region Feb 9, 2007
Alvaro says, "Anybody, for example, who has diabetes and has developed an ulceration because of the diabetes, people with arterial problems, people with radiation tissue damage if they've had cancer years ago." Patients using the hyperbaric chambers will go through between 30 and 60 treatments and each treatment inside one of the chambers lasts 106 minutes. Alvaro says the patients respond incredibly well. (FOX23 News, NY)
Parents Turn to Clinics for Genital Mutilation - U.N. Feb 6, 2007
Immediate complications include severe pain, shock, hemorrhage, urine retention, ulceration of the genital region and injury to adjacent tissue. Hemorrhage and infection can cause death, the World health Organization said. (ABC News)
Living with Diabetes Jan 30, 2007
Foot care is very important for the diabetic contact your doctor immediately whenever foot ulceration occurs. Early medical attention is important. (Suite101.com)
Unusual lesions will fade over time Jan 7, 2007
Scarring may occur in areas where there was an ulceration. Lichen planus in mucous membranes, such as the mouth or genital areas, may increase the risk of skin cancer. (Orlando Sentinel -- News)
Xilas touts new study on diabetic foot-care treatment Jan 4, 2007
Use of the TempTouch home infrared temperature probe significantly reduced the frequency of foot ulceration in people with diabetes, according to the results of a clinical study published in the January 2007 issue of Diabetes Care ... The key results of the Phase II clinical trial was that the level of ulceration for those using TempTouch was 8 ... "People with diabetes that are high-risk ... are very likely to have follow-on foot problems. Re-ulceration rates can be as high as 58 percent to 83... (San Antonio Business Journal, TX)
A Cure Can Be In Vein Dec 26, 2006
For most, the vein problem is merely cosmetic, although for some, it can cause burning, itching and throbbing in the affected leg, swelling, cramping and fatigue - and even result in ulceration and bleeding. While spider veins are in the top layer of skin and varicose usually deeper, both have the same cause: Veins have one-way valves to prevent blood from flowing backwards, and when the valves don't close properly, blood can leak through and pool in the vein, causing them to enlarge or bulge. (New York Post -- Entertainment)
Body Parts: Tears are good for eyes Dec 3, 2006
Dry eye can cause corneal ulceration. Dry eye symptoms can be temporarily relieved with "artificial tears," a lubricating solution given in eyedrops. (North County Times)
Bleeding has many causes Dec 1, 2006
Another common cause of abdominal bleeding is peptic ulceration, either gastric or duodenal ulcers. These are less frequently seen after the introduction of efficient antacid medication. (TimesOnline)
Vitamin D Deficiency Common in Children with Inflammatory Bowel Disease Nov 29, 2006
Inflammatory bowel disease refers to the inflammation of the large or small colon and is characterized by diarrhea, abdominal pain and cramping, bloody stool, weight and appetite loss, and ulceration of the bowel lining. Crohn's disease and ulcerative colitis are two common types of inflammatory bowel disease. (MEDLINEplus)
The computer that could transform diabetics' lives Nov 7, 2006
By delivering the correct amount of insulin as soon as it is needed, it should reduce long-term complications such as blindness, loss of sensation and ulceration of the feet, which can lead to amputation. Clinical trials will start in January. (Times Online)
Obesity pill seen as new wayto treat diabetes Oct 28, 2006
Reducing weight and controlling glucose levels is important because diabetics have an increased risk of heart disease, stroke, blindness, kidney damage and nerve disorder that can lead to foot ulceration and amputations. Type 2 diabetes is a difficult disease to treat because we have had no optimal drugs until now, Scheen told Reuters. (MSNBC -- Health)
PDL BioPharma and The European Crohn's and Colitis Organization Collaborate to Support Global Clinical Trial Program for Severe IV Steroid Refractory Ulcerative Colitis Oct 23, 2006
About Ulcerative Colitis Ulcerative colitis is a chronic disease caused by an abnormality in the body's immune system that leads to inflammation and ulceration of the innermost lining of the colon (or large intestine), which can cause diarrhea, pain and bleeding. In severe cases, individuals may have diarrhea 10 to 20 times a day, which may lead to dehydration, fever, hospitalization and the need for blood transfusions. (PR Newswire)
Handling heartburn| Oct 17, 2006
This causes inflammation of the oesophagus, swelling of the whole area, bleeding, ulceration, and eventually a condition called Barrett's oesophagus. This describes severe damage to the lining of the oesophagus, which seems to predispose to a particular type of oesophageal cancer. (iAfrica.com)
Diabetes could cripple health budgets Sep 14, 2006
The illness also increases the risk of heart disease, stroke, blindness, kidney damage and nerve disorders that can lead to foot ulceration and amputations. Most of the new cases will be Type 2 diabetes, which could be prevented by lifestyle changes such as increased exercise and a healthy diet, according to the IDF.. (Sydney Morning Herald -- World)
Sheep and Goat Diseases Outlined From A to Z Sep 8, 2006
"The constant irritation results in tearing and can lead to corneal ulceration, scarring and blindness," Schoenian says ... Ammonia produced by excess urea in the ram's urine can cause severe irritation and ulceration of the skin around the penis, and a crust might eventually block the opening, affecting a ram's desire and ability to breed. (Agri-View, WI)
3-in-1 heart pill could save millions Sep 6, 2006
Verheugt warns that the drugs to be included in the polypill have potentially serious side effects, such as gastric intestinal ulceration and bleeding, which would complicate its distribution in large populations. "Physicians need to monitor what they're giving their patients, to make sure that they tolerate it well," Verheugt said, explaining that simply handing out the polypill wouldn't necessarily lessen the burden on the public health system. (Houston Chronicle)
Pine tree bark reduces diabetic leg ulcers Sep 6, 2006
A study published in the July journal of Clinical and Applied Thrombosis/Hemostasis shows that Pycnogenol (pic-noj-en-all), an antioxidant plant extract from the bark of the French maritime pine tree, heals leg ulcers in patients who suffer from diabetic leg ulcerations ... The study sampled thirty diabetic patients at the Chieti-Pescara University in Italy, who suffer from severe microangiopathy causing leg ulcerations ... The area of the ulceration was copied on a transparent plastic sheet... (EurekAlert!)
