Blood Test for Parkinson's Shows Promise Mar 25, 2008
These included significantly reduced concentrations of the antioxidant uric acid and an increase in another antioxidant, glutathione. Results also showed increased levels of 8-OHdG -- a marker of oxidative damage to DNA -- but there was considerable overlap between Parkinson's patients and controls. (MEDLINEplus)
Ghanaians Drinking Less Water Mar 23, 2008
Giving the medical benefits of water to the body, Dr Addai said in the kidneys water removes wastes such as uric acid; urea and lactic acid; all of which must be dissolved in water. When there isn't sufficient water, those wastes are not effectively removed, which may result in damage to the kidneys. (Ghana Web, Ghana)
Uric Acid May Provide Early Clues To Diabetic Kidney Disease Mar 22, 2008
21, 2008) For patients with type 1 diabetes, increased levels of uric acid in the blood may be an early sign of diabetic kidney disease--appearing before any significant change in urine albumin level, the standard screening test, reports a study in the May 2008 issue of the Clinical Journal of the American Society of Nephrology ... The results raise the possibility that treatments to reduce uric acid might slow the decline of renal function in patients with diabetes ... The researchers measured... (Science Daily)
The tale of a royal pain in the toe Mar 22, 2008
Because, oh king, the physician explained, your blood contains high amounts of a substance called uric acid ... Purines are the source of uric acid that can aggravate your painful gout ... " the king inquired. Call for the royal pharmacist, said the physician. He will prepare medicines to help prevent the formation of uric acid crystals in your joints.". (Corvallis Gazette Times, OR)
Gene 'linked to higher gout risk' Mar 10, 2008
In a healthy body, uric acid, a waste product found in the blood, is removed by the kidneys and passes out of the body in urine ... The gene variation they found, in the SLC2A gene, appears to make it harder for the body to remove uric acid from the blood ... Professor Alan Wright, who led the research, said: "The gene is a key player in determining the efficiency of uric acid transport across the membranes of the kidney.". (BBC News -- UK)
Urine Protein May Be Present Before Hypertension Diagnosis In At-risk Adolescents Mar 1, 2008
3, 2006) New research shows that higher levels of uric acid are strongly associated with high blood pressure in African Americans, suggesting that a simple blood test could predict risk and that treatments to. . (Science Daily)
Smoking ban sparks dispute of wood-burning stoves, fireplaces Feb 27, 2008
" Reality to Pants wrote on Feb 25, 2008 4:17 PM:" What are the facts that wood that I cut and chop out in a thicket or grove is more harmful than cigarettes with ammonia, uric acid, cyanide residue, fiberglass residue for menthols, etc. What is your argument that us demanding this guy to pay our gas bill should be considered equality for casinos and bar owners have us pay for their losses. (The Pantagraph newspaper)
Yamuna: A ghariyal killer? Feb 22, 2008
The bodies show uric acid deposition in visceral organs and also in joints of animals. This point towards kidney failure and toxin, according to the findings so far, as the cause. (India Times, India)
New Finding May Help Explain Development Of Preeclampsia Feb 12, 2008
29, 2005) Pregnant women with hypertension who also have elevated levels of uric acid in their blood may face an increased risk of complications that could be fatal for mother and baby, University of. . (Science Daily)
Sugary Soft Drinks Linked To Increased Risk Of Gout In Men Feb 2, 2008
It is caused by excess uric acid in the blood (hyperuricaemia) which leads to uric acid crystals collecting around the joints. In the United States, levels of gout have doubled over the last few decades, which coincided with a substantial increase in the consumption of soft drinks and fructose (a simple sugar and the only carbohydrate known to increase uric acid levels) ... (May 25, 2007) Among its complex effects on the body, coffee or its components have been linked to lower insulin and uric... (Science Daily)
Fizzy drinks linked to gout Feb 2, 2008
Gout is caused by a build-up of uric acid in the bloodstream and can cause joint swelling, inflammation and acute pain in the extremities. Uric acid is produced by the kidneys and digestive system from purines, which normally occur in rich food, meat and beer. (Guardian Unlimited)
Blood analysis screening under way Jan 30, 2008
May 6 The screening will include the following tests: glucose, BUN, creatinine, SGPT, total bilirubin, alkaline phosphatase, triglyceride, cholesterol, HDL cholesterol, LDL cholesterol, total protein, albumin, uric acid, iron, sodium, potassium, chloride, calcium, TSH, white and red blood cell count, hemoglobin, hematocrit and platelet count. Appointments required Appointments MUST be made for the blood analysis screening. (Harlan Tribune, IA)
Common Types of Arthritis Jan 27, 2008
Gout is the result of years of accumulation of uric acid in the joints, which causes the pain and swelling. Uric acid is the product of purine metabolism, thus taking increased amounts of purine will lead to increased accumulation of uric acid ... Presence of uric acid crystals on microscopic examination of synvoial fluid indicates gout. (Suite101.com)
Judah Folkman, 74; pioneer in cancer treatment Jan 18, 2008
His theory received a near-fatal blow when other researchers implanted crystals of uric acid near the iris and also observed the growth of new blood vessels, suggesting that inflammation was the culprit. "That silenced us for a couple of years," Folkman later said. (Los Angeles Times)
A Woman with Postpartum Visual Loss, Shortness of Breath, and Renal Failure Jan 17, 2008
Aminotransferase and uric acid levels were normal. . (New England Journal of Medicine)
The prevalence and impact of arthritis and other rheumatic conditions in the United States Jan 3, 2008
An inflammatory arthritis linked to elevated uric acid in the blood, gout tends to be most prevalent among older men and more prevalent in older African American males than in older white or Hispanic males. Juvenile Arthritis: Based on recent data from pediatric ambulatory care visits, an estimated 294,000 children between the ages of infancy and 17 are affected by arthritis or other rheumatic conditions. (EurekAlert!)
Gout is no joke. This I know from painful experience Dec 22, 2007
Daily pills reduce the levels of uric acid that form the crystals which lodge in the joints to produce gout. Who knows, in 2008 I may even go on a walking holiday again. (Guardian Unlimited)
Savient's Gout-Buster Dec 14, 2007
Gout, which is caused by excessive amounts of uric acid, is a severe form of arthritis and causes sudden pain and swelling in joints ... For those in this group, Savient estimates that allopurinol, the main therapy for control of uric acid, has failed to treat up to 100,000 patients, leaving tens of thousands without treatment options ... "We believe that the Phase 3 data show that pegloticase (Puricase) has the potential to be the first effective therapeutic option to control uric acid in... (Forbes -- Markets)
Too much fructose could leave dieters sugar shocked Dec 13, 2007
Eating too much fructose causes uric acid levels to spike, which can block the ability of insulin to regulate how body cells use and store sugar and other nutrients for energy, leading to obesity, metabolic syndrome and type 2 diabetes, said Johnson, the division chief of nephrology and the J. Robert Cade professor of nephrology in the UF College of Medicine. UF researchers first detailed the role of uric acid on insulin resistance and obesity in a 2005 study in rats. (EurekAlert!)
Oil stops flirting with $100 a barrel Nov 29, 2007
Ardea conducted a Phase 1 study that showed that its RDEA806, which had been evaluated as a potential treatment for HIV, reduced serum uric acid, which contributes to gout. The company is preparing to initiate a Phase 2 efficacy study in gout patients. (San Diego Union-Tribune -- Business)
Discovery About Urine May Lead To Hypertension Treatment Nov 16, 2007
3, 2006) New research shows that higher levels of uric acid are strongly associated with high blood pressure in African Americans, suggesting that a simple blood test could predict risk and that treatments to. (Jun. (Science Daily)
Phase III Study Reveals Potential New Therapy For Gout Nov 13, 2007
(May 25, 2007) Among its complex effects on the body, coffee or its components have been linked to lower insulin and uric acid levels on a short-term basis or cross-sectionally. These and other mechanisms suggest. (Science Daily)
Gout May Protect Against Parkinson's Disease Nov 10, 2007
Gout is caused by high levels of uric acid in the blood. And while several studies have suggested that higher levels of uric acid are associated with a lower risk of Parkinson's disease, none of these studies have specifically evaluated the potential association between gout and the risk of Parkinson's ... Alonso and colleagues note that different biologic mechanisms might explain the association between gout, high uric acid levels, and lower risk of Parkinson's. (MEDLINEplus)
Decreased blood antioxidant capacity and increased lipid peroxidation in young cigarette smokers compared to nonsmokers: Impact of dietary intake Nov 9, 2007
We compared resting plasma antioxidant reducing capacity (ARC; expressed in uric acid equivalents), serum trolox-equivalent antioxidant capacity (TEAC), whole blood total glutathione, plasma malondialdehyde (MDA), and plasma oxidized low density lipoprotein (oxLDL) between 15 young (24+/-4 years), novice smokers (pack-year history: 3+/-2) and 13 nonsmokers of similar age (24+/-5 years). Detailed dietary records were maintained during a seven-day period for analysis of total energy, macro- and... (Nutrition Journal)
Arthritis may predispose patients to gout Oct 13, 2007
NEW YORK (Reuters Health) - Arthritis may trigger the deposit of uric acid crystals in joints, the main cause of gout, according to a report in Annals of the Rheumatic Diseases. Case reports and hospital-based case series have linked gout with the presence of arthritis in the same joints, the authors explain. (Scientific American)
Mini-strokes Linked To Uric Acid Levels Oct 6, 2007
Researchers at Johns Hopkins have found that high-normal uric acid (UA) levels may cause barely detectable mini strokes that potentially contribute to mental decline in aging adults. Diet, exercise and drugs like allopurinol (all of which lower UA levels) could eventually be of value in reducing this risk, especially for those with additional risk factors such as diabetes, obesity and hypertension, the researchers say. (Science Daily)
Clue to chemistry of mini-strokes Oct 2, 2007
Elevated levels of uric acid may be to blame for mini-strokes that potentially cause mental decline in ageing adults. Brain scans showed mini-strokes - white matter hypersensitivities (WMHs) - were more common among elderly patients with higher uric acid levels ... Having found that uric acid levels are linked to both mild cognitive decline and mini strokes we need to learn how these are related. (BBC News -- Health)
Are Humans Omnivores? Sep 29, 2007
Carnivores also secrete the enzyme uricase which breaks down uric acid in meat. By comparison herbivores have long digestive tracts and digestion begins in the mouth. (Suite101.com)
The Definition of Protein Sep 29, 2007
Since the body cannot store unused protein it will be converted into urea which can form into uric acid and make the blood acidic. The most important thing to remember in all of this is that digestion will always result in waste products and the more complete digestion is the fewer wastes produced. (Suite101.com)
Add these vines to chain link for privacy Sep 27, 2007
The white part of each dropping is uric acid which was deposited internally onto their fecal matter. It isn't likely the reptiles will be a permanent problem. (Atlanta Journal-Constitution)
Sugary Drinks May Raise Uric Acid Levels in Men Aug 21, 2007
NEW YORK (Reuters Health) - A higher intake of added sugars or sugar-sweetened drinks may lead to higher blood levels of uric acid in men, a study suggests ... High serum uric acid, they explain, has been suggested as a possible risk factor for high blood pressure, heart and vascular disease, as well as metabolic syndrome -- a cluster of risk factors, such as high blood pressure, obesity and high blood sugar levels, that together increase the likelihood of developing heart problems or diabetes... (MEDLINEplus)
Stool Pigeons Aug 15, 2007
According to MnDOT reports, the uric acid in pigeon droppings is highly corrosive and may have contributed to metal fatigue on parts of the bridge. Yet the question remains: Who sent the pigeons to shit all over America's infrastructure. (City Pages)
523000 a day on alternative medicine Jul 28, 2007
are a build up of uric acid (ugh)4 ... If your arthritis is of the uric acid type, you will be relieved of your pain within a month. (Scotsman)
Living with arthritis Jul 27, 2007
An attack can begin when crystals of uric acid form in the connective tissue and/or joint spaces. These deposits lead to swelling, redness, heat, pain and stiffness. (Marco Island Sun-Times, FL)
High Blood Urate Tied to Lower Parkinson's Risk Jul 13, 2007
NEW YORK (Reuters Health) - High blood levels of urate -- a salt derived from uric acid -- are associated with a decreased risk of Parkinson's disease, researchers report. The finding suggests that urate levels could serve as a biological marker for Parkinson's disease risk, Dr. Marc G. Weisskopf, of the Harvard School of Public Health in Boston and the study's lead author, told Reuters Health. (MEDLINEplus)
Robotic bathrooms make him flush with anger Jul 12, 2007
He continued: "Automatic soap dispensing systems provide just the right amount of soap for an efficacious washing. AutoFlush products and AutoClean systems for toilets and urinals reduce maintenance costs by preventing stains and damage from uric acid and calcium deposits. Everyone benefits from these and other features, from facility owners to building service contractors to consuming customers using the rest rooms" (emphases added). See what the canny chief executive is up to. (Newsday -- Opinion)
Whitey and Mickey: Be Good Boys Jul 1, 2007
To sweeten the pot, Ford's salary was increased to $37,000 and the Yankees explained to Whitey that the conditions the club wanted to impose did not involve his being a "good boy," but rather required that he observe specific dietary restrictions in order to control his high uric acid condition ... It was the fact that Whitey had missed too many starts the last two seasons due to arm problems that were traced to his uric acid levels, which is a form of gout. (Suite101.com)
Clinical Trials Update: June 27, 2007 Jun 28, 2007
Diabetes Mellitus, Type 2. Gout (Hyperuricemia). (Health-Finder)
Stay Hydrated This Summer To Prevent Painful Kidney Stones Jun 6, 2007
Other types of stones contain uric acid, are related to urinary tract infections or are cystine stones that are caused by a genetic abnormality. Typically, stones are passed spontaneously. (Science Daily)
Coffee detox? Jun 6, 2007
But some newly published research suggests drinking coffee can help reduce unhealthy levels of uric acid in the bloodstream. Uric acid is a natural waste product from the breakdown of foods containing purines, and normally is regularly flushed out through the kidneys ... But some people either produce excessive amounts of uric acid or don't eliminate it efficiently. (Boulder Colorado Daily, CO)
Doctors have no doubt about a return of gout Jun 6, 2007
The crystals form when there is a high level of uric acid in the body, often from the breakdown of energy-providing compounds called purines in foods. While a patient may have a high concentration of uric acid in the blood for a long time with no symptoms, rich foods and alcohol can trigger a painful attack of gout, most often in the big toe ... High-protein, low-carbohydrate diets have contributed to the rise in gout, according to Joan McTigue, a member of the board of directors for the Gout &... (Orlando Sentinel)
Time to tone up Jun 6, 2007
When you're trying to lose weight in a short amount of time, you need about four to six glasses of water a day to help flush out the excess uric acid. Keep a food journal. (San Diego Union-Tribune)
Drinking coffee may help prevent gout Jun 4, 2007
The findings show that among its complex effects on the body, coffee or its components have been linked to lower insulin and uric acid levels on a short-term basis or cross-sectionally, said the study by. These and other mechanisms suggest that coffee consumption may affect the risk of gout. (People's Daily Online)
Got gout? Get coffee! May 30, 2007
BEIJING, May 28 (Xinhuanet) -- In the past, people at risk for gout were told by doctors to avoid coffee, but Canadian researchers on Friday said four or more cups a day may help ward off the painful joint disorder caused by a buildup of uric acid in the blood ... The researchers found significantly lower levels of uric acid in the blood of those who consumed large quantities of coffee ... Uric acid is the compound that causes gout. (Xinhuanet, China)
Health study raises concerns with outdoor smoking May 30, 2007
People who have gout experience attacks of arthritis that come on suddenly and are caused by excessive levels of uric acid. The uric acid causes an accumulation of crystals in the joints ... The researchers said there might be a number of reasons that coffee lowered the risk, among them its tendency to lower uric acid levels in the blood. (International Herald Tribune)
Drinking coffee may reduce risk of gout May 29, 2007
Gout is a painful condition that occurs when uric acid, a natural waste product formed in the body, is deposited as crystals in the joints and/or soft tissues, causing inflammatory arthritis, according to the National Institute of Arthritis and Musculoskeletal and Skin Diseases ... Studies also show drinking coffee for a short term lowers insulin and uric acid, indicating that coffee may have any effect on the risk of gout ... The authors suspected chlorogenic acid, a strong antioxidant found in... (Food Consumer)
Four to six cups of Joe may calm gout May 28, 2007
Gout is a disease, which affects mostly adult men, that causes swollen and painful joints (and eventually inflammatory arthritis) due to production of excessive uric acid that goes into the joints, especially those in the toes and feet. The researchers, from the Arthritis Research Center of Canada, University of British Columbia in Canada, Brigham and Women s Hospital, Harvard Medical School, and Harvard School of Public Health in Boston, studied nearly 46,000 men, between the ages of 40 and 75... (iTWire)
Lower gout risk for coffee lovers May 26, 2007
A University of British Columbia team found blood uric acid levels - which are linked to the condition - were lower in people who drank more coffee ... Its symptoms, which are often joint pains in the lower limbs, happen when uric acid crystallises out of the blood into the joints ... The main way to tackle the condition is to take anti-inflammatory pills, change diet and drink more water, or in more severe cases, to take more powerful drugs to reduce uric acid levels in the blood. (BBC News)
RoundTable Collaborates With Bioniche Pharma on Key Growth Developments May 26, 2007
7 million acquisition of Aloprim (allopurinol sodium) for Injection from Nabi Biopharmaceuticals, and the acquisition of Esmolol Hydrochloride ("Esmolol") from Metrics Pharmaceutical Ventures, LLC. Aloprim for Injection is indicated for the management of patients with leukemia, lymphoma, and solid-tumor malignancies who are receiving cancer therapy that cause elevations of serum and urinary uric acid levels. Esmolol is a generic injectable cardiology product indicated for the treatment of... (PR Newswire)
Coffee can cut painful gout May 26, 2007
The results showed that levels of uric acid decreased as coffee intake rose. Once again, the study noted a beneficial effect of chlorogenic acid in coffee. (Canada.com)
Coffee may cut risk of gout, study finds May 25, 2007
Gout is a painful joint disorder caused by a buildup of uric acid in the blood ... The researchers found significantly lower levels of uric acid in the blood of those who consumed large quantities of coffee ... Uric acid is the compound that causes gout. (Scientific American)
Large Jolts of Java Can Keep Gout at Bay May 25, 2007
Gout, the most common form of inflammatory arthritis in adult males, is caused by too much uric acid in the joints ... "Given the potential influence of female hormones on the risk of gout in women and an increased role of dietary impact on uric acid levels among patients with existing gout, prospective studies of these populations would be valuable," he added. (Health-Finder)
Coffee consumption may lower blood uric acid levels -- The precursor of gout May 25, 2007
High uric acid levels in the blood are a precursor of gout, the most common inflammatory arthritis in adult men. It is believed that coffee and tea consumption may affect uric acid levels but only one study has been conducted to date ... A new large-scale study published in the June 2007 issue of Arthritis Care rch () examined the relationship between coffee, tea, caffeine intake, and uric acid levels and found that coffee consumption is associated with lower uric acid levels but that this... (EurekAlert!)
Drinking 4 or more cups of coffee a day may help prevent gout May 25, 2007
Among its complex effects on the body, coffee or its components have been linked to lower insulin and uric acid levels on a short-term basis or cross-sectionally ... "Given the potential influence of female hormones on the risk of gout in women and an increased role of dietary impact on uric acid levels among patients with existing gout, prospective studies of these populations would be valuable.". (EurekAlert!)
Watch What You Put In That Sippy Cup, Experts Warn May 22, 2007
Fructose and high-fructose corn syrup, a sweetener used in most soft drinks, also cause the body to produce more uric acid. In 2005, Johnson and other UF researchers showed that feeding a high-fructose diet to rats raised uric acid levels, leading to insulin resistance ... When they lowered the amount of uric acid in rats, their rates of obesity and insulin resistance fell too. (Science Daily)
Just what you ordered May 8, 2007
Self-ordered tests for cholesterol, glucose, potassium and uric acid cost $6 each. The most expensive tests, at $65 each, are for vitamin B12/folate and the iron function panel. (Durango Herald)
Simple saliva test could save lives of 1000 babies a year May 7, 2007
It monitors raised levels of urate, a salt of uric acid, which is a waste product produced by the body. High levels of urate can be an indicator of pre-eclampsia. (Scotsman)
Simple home spit test to spot deadly pre-eclampsia May 7, 2007
The new test works by monitoring levels of urate, a salt of uric acid, increased levels of which are thought to be due to impaired kidney excretion in pre-eclampsia. A salivary urate test is simple, non-invasive, quick and cheap and can be done at any time. (EurekAlert!)
Nabi lowers Q1 loss May 3, 2007
Last month, the company Aloprim, a drug that treats chemotherapy-induced hyperuricemia (a high level of uric acid in the blood), to Bioniche Teoranta for staggered proceeds totaling $3. 7 million. (South Florida Business Journal, FL)
Letter: Supreme Court adds to the level of hot air Apr 23, 2007
Incidentally, as to the start on this article, did you know that you had better not produce flatulent (hydrogen sulfide) or urinate (uric acid) as both are on the EPA s list as pollutants and might put you in the pokey. Share. (Mattoon Journal-Gazette, IL)
RoundTable Healthcare Partners Facilitates Product Acquisition for Bioniche Pharma Apr 20, 2007
Aloprim for Injection is indicated for the management of patients with leukemia, lymphoma, and solid-tumor malignancies who are receiving cancer therapy that cause elevations of serum and urinary uric acid levels. Bioniche Pharma is a leading developer and manufacturer of injectable generic pharmaceuticals. (PR Newswire)
Nabi sells Aloprim for $3.7M Apr 20, 2007
The Boca Raton-based biotech had bought Aloprim, which treats chemotherapy-induced hyperuricemia (a high level of uric acid in the blood), from DSM Pharmacueticals for $1. 8 million in 2004. (South Florida Business Journal, FL)
Avoiding certain foods can help prevent a bout with gout Apr 18, 2007
Gout is a condition in which uric acid is deposited in the body's joints ... Gout occurs in people who have abnormally high levels of uric acid ... Your body may make too much, or it may have trouble getting rid of uric acid. (The Daily Reflector)
Comfort and Joy We'll Take the Train... Apr 7, 2007
Our only problem: the cleverly disguised commode in our compartment smelled so sharply of uric acid that 30 minutes into the journey, my girl was turning green. I went to our steward Cornelius, but every other compartment smelled as bad. (Voices, CT)
Who was better: Newton or Einstein? Mar 24, 2007
It might, but the levels of uric acid in the sea would increase to offset any gain. Sandy Parkinson, Hilton WA. (Sydney Morning Herald -- Entertainment)
