Spanish cyclist wins Tour de France (Yesterday) Jul 29, 2008
The stimulant is used as a vasodilator that helps relieve bronchial spasms. "Fofonov said he bought the product on the Internet," said Roger Legeay, sporting director of Credit Agricole. (Pittsburgh Post-Gazette, PA -- Sports)
Little suckers clear the path to the brain Jul 26, 2008
More than 50 Richardsonianus australis leeches are kept in a tank at Liverpool Hospital for use on patients who have had skin grafts or severed digits because their saliva contains hirudin, a chemical that acts as a powerful anticoagulant and vasodilator. But using them on patients with severe cardiovascular disease has not yet become established practice in Australia. (Sydney Morning Herald -- Australia)
Migraine Triggers And Fighters Jun 17, 2008
Mechanism: amino acid and vasodilator. Found in: aged cheese, wine, chocolate, smoked, cured or pickled meat, processed meats, tofu, some fruits and vegetables such as eggplant, avocado, bananas and raspberries. (CBS News -- Early Show)
Researchers discover new way to reverse poor circulation and heal wounds Feb 15, 2008
This confirmed that the fragment signals for dilation by causing the release of the well-known vasodilator, nitric oxide, and perhaps by binding to heparan sulfate proteoglycan molecules on the surface of smooth muscle cells. It takes energy to move fibronectin out of the bloodstream, assemble it into ECM fibrils, and open its cryptic site, Hocking said. (EurekAlert!)
Diabetes Makes It Hard For Blood Vessels To Relax Feb 2, 2008
It also means too little L-arginine is available to help nitric oxide synthase make nitric oxide, the powerful vasodilator that helps blood vessels relax, says Dr. Romero, who works in the lab of Dr. R. William Caldwell, chair of the MCG Department of Pharmacology and Toxicology and the study's corresponding author. Researchers also found the amino acid, L-citrulline, as well as statins, compounds known to lower cholesterol, prevent elevation of arginase activity, restoring normal dilation... (Science Daily)
Cure Wrinkles with New Chili Pepper Based Wrinkle Cream Jan 29, 2008
Capsaicin is a vasodilator that naturally increases blood flow to the skin. Blair recently created a facial cream that is as gentle on the skin as it is powerful. (Yahoo News -- Press Releases)
How The Brain Regulates Blood Flow To Neurons: Powerful Enzyme Could Play Key Role In Alzheimer's Disease Jan 19, 2008
"We found that this natural tPA boosts blood flow to brain cells via its influence on nitric oxide synthase, which is essential to the production of nitric oxide (NO). NO is a well-known vasodilator a drug or chemical that widens blood vessels so, more NO means better blood flow to neurons as they become more active," explains study senior author Dr. Costantino Iadecola, the George C. Cotzias Distinguished Professor of Neurology and Neuroscience at Weill Cornell Medical College, and chief of the... (Science Daily)
Cardiovascular Diseases: New Hemoglobin Function Discovered Nov 6, 2007
In a paper published in Nature Chemical Biology, senior authors Daniel Kim-Shapiro, professor of physics at Wake Forest, and Mark Gladwin, chief of the Vascular Medicine Branch of the National Heart, Lung and Blood Institute of the NIH, describe how hemoglobin, through a catalytic reaction that does not change its own chemical properties, converts nitrite salt to the vasodilator nitric oxide. The paper further documents how the nitric oxide activity harnessed by hemoglobin escapes the red blood... (Science Daily)
Physical Therapy In ICU Can Reduce Hospital Stays Oct 24, 2007
24, 2007) The results of the first study to show the effectiveness of early physical therapy in a medical intensive care unit (ICU) are being presented October 23 by a researcher from Wake Forest University Baptist Medical Center at the national meeting of the American College of Chest Physicians in Chicago. The length of stay for a group of respiratory-failure patients who received mobility therapy within 48 hours of the insertion of a breathing tube was reduced by an average of three days... (Science Daily)
Studies Probe Weaknesses in Donated Blood Oct 9, 2007
Nitric oxide (NO) is a vasodilator -- a compound that opens (dilates) blood vessels ... They found that human red cells' vasodilatory activity could be restored at any point up to 40 days following collection by treatment with NO, thereby improving blood flow to the heart in blood recipients. (Health-Finder)
Dr. James Young Appointed Principal Investigator for Vasogen's Confirmatory Study in NYHA Class II Heart Failure Sep 19, 2007
He subsequently focused his efforts on heart failure and cardiac transplant therapeutics which included early experiences with dopamine receptor agonists, angiotensin-converting enzyme inhibitors, beta blockers, calcium channel blockers, angiotensin receptor blockers, many new immunosuppressants, and a variety of parenteral inotropes and vasodilators. He has collaborated extensively with his basic science research associates at the Kaufman Center for Heart Failure and the Multi-organ Transplant... (Canada Newswire)
New Therapy Could Preserve Vessel Function After Heart Attack Sep 17, 2007
Zweier and colleagues set out to determine the cascade of events that leads to the loss of vessel vasodilatory function and, in the process, identified a potential solution that would dilate and reopen vessels, improving blood flow ... This stoppage can be traced to depletion during ischemia of a molecule that is a critical cofactor required to activate the enzyme nitric oxide synthase (NOS), which produces the potent vasodilator nitric oxide. (Science Daily)
High Growth Forecasted in the Global Medical Imaging Markets Sep 7, 2007
12 Vasodilator Perfusion Imaging ... 5 Vasodilator Perfusion Imaging. (BusinessWire)
Race in a Bottle Jul 17, 2007
In the early 1980s Jay Cohn, a cardiologist at the University of Minnesota, hypothesized that administering two vasodilators, hydralazine and isosorbide dinitrate, might ease the strain on weakened hearts by relaxing both the arteries and veins. Together with the U.S. Veterans Administration, Cohn designed and conducted two trials to assess this theory. (Scientific American)
Foods Counteract Drugs' Effects Jul 17, 2007
Beta-blockers and vasodilators. These drugs lower high blood pressure but they also deplete coenzyme Q10 (beta-blockers) and vitamin B6 (vasodilators) causing fatigue, anemia, and weakened muscles. (Newsmax)
Method To Prevent Hemorrhagic Complications Of Thrombolytic Therapy Of Blood Clots Is Discovered Jul 6, 2007
In addition to proteolytic enzymes, mast cells release vasodilators such as histamine as well as heparin (s. c. "blood thinning" anticoagulant drug), which may locally prevent blood coagulation, predispose to bleeding and edema formation and ultimately lead to hazardous expansion of hemorrhagic and edematous brain events. (Science Daily)
Spain hit by plague of blood-sucking black flies Jun 25, 2007
The insect injects an anaesthetic, an anti-clotting agent and a vasodilator into the skin of its host, who belatedly notices the damage after the fly has moved on. In Switzerland an attacking swarm reportedly killed a calf. (Guardian Unlimited)
New Bladder Infection Treatment May 31, 2007
Commonly used as a vasodilator, Forskolin may be your new treatment protocol in dealing with urinary tract infections. Forskolin is an extract from the Indian coleus plant that has been used for centuries in Ayurvedic medicine as a treatment for urinary problems. (Suite101.com)
Teaching, research hailed May 16, 2007
His research focuses on a protein that is the most potent vasodilator known, maxadilan. Lanzaro demonstrated that maxadilan levels in sand flies is correlated with disease severity. (Davis Enterprise, CA)
New study reports improved treatment and reduced mortality for patients with heart failure May 2, 2007
FINDINGS: Treatment changes included decreased use of intravenous inotropic agents (drugs that make the heart work harder) and increased use of intravenous vasodilators (drugs that reduce the work the heart needs to do to help blood flow). A substantial rise in the use of oral beta-blocker medication during hospitalization was also found. (EurekAlert!)
Effects of Dietary Nitrate on Blood Pressure Apr 12, 2007
In studies conducted over the past 5 years, we have shown that nitrite is an intrinsic vasodilator. 2,3 Within the vasculature, nitrite is. (New England Journal of Medicine)
Erectile Dysfunction Drugs May Trump Nitroglycerin For Heart Protection Mar 4, 2007
It is a vasodilator and opens blood vessels in order to improve the flow of blood to a patient's heart. The research team reported that in an animal model, sildenafil and vardenafil reduce damage in the heart muscle when given after a severe heart attack. (Science Daily)
Beyond impotenceViagra is not just a drug to pep up your sex life Feb 18, 2007
Vicky Styman of the British Heart Foundation explained: "It is a potent vasodilator, opening up the blood vessels and it was originally looked at as a heart drug.". But there have been concerns about whether it is safe for men with heart disease on particular medications that work in the same way. (BBC News -- Health)
Simple, Noninvasive Test Measures Survival Time In Adult Pulmonary Hypertension Nov 4, 2006
(November 2, 2006) -- A single dose of sildenafil, a blood vessel widening vasodilator (also sold under the brand name Viagra), prevented rebound pulmonary hypertension and significantly reduced the duration of mechanical. . (Science Daily)
Viagra For Babies? Sildenafil Found To Prevent Rebound Pulmonary Hypertension In Infants Nov 3, 2006
A single dose of sildenafil, a blood vessel widening vasodilator (also sold under the brand name Viagra), prevented rebound pulmonary hypertension and significantly reduced the duration of mechanical ventilation in intensive care unit (ICU) infants being withdrawn from inhaled nitric oxide therapy ... Although there have been no definitive studies of clinical benefit to date, the investigators believe that inhaled nitric oxide therapy warrants use as an adjunctive treatment in some of the... (Science Daily)
VIP's importance to temperature regulation may be pre-empted by substance P Oct 25, 2006
"What we've found is that the NK-1 receptor pathway is a major player in this response, and this finding could represent a paradigm shift. Our data implicate the NK-1 receptor pathway, and the primary neurotransmitter for this receptor in humans is substance P, suggesting that this is the putative vasodilator located in specialized skin nerves. However, more work is necessary to clearly define its role in heat stress and other physiological responses.". In the study, the participants were lying... (EurekAlert!)
Histamine tied to changes in blood pressure during exercise-recovery period Oct 11, 2006
"There is reason to believe that histamine is the primary vasodilator contributing to post-exercise hypotension, but we cannot say for certain," cautioned principal investigator John R. Halliwill, a professor of human physiology. "Some people have problems regulating blood pressure during and after exercise. Trained athletes have had fainting bouts at the end of exercise. It may be that these result from a natural overactivation of these two receptors for histamine.". (EurekAlert!)
Leveling The Field For Babies With Persistent Pulmonary Hypertension Oct 8, 2006
If it is pulmonary hypertension, the powerful vasodilator, nitric oxide, is used to reduce high pressures in the pulmonary circuit and allow the transition to a normal circulation ... The main vasodilator in the lungs is nitric oxide and the main vasoconstrictor is endothelin ... When you lose the vasodilator and you gain proliferative response, essentially the muscle cells just get bigger. (Science Daily)
24/7: From Wharton to Intensive Care Aug 11, 2006
10:25 p.m. The blood pressure remains high, so we start other vasodilators to try to lower it. In the meantime, I am still pushing fluid into the patient. (BusinessWeek)
Scientists working on pain prevention and management Jul 1, 2006
In the kidneys, vasodilator PGs widen blood vessels, helping to maintain renal blood flow and to protect kidney function. Zambraski said one goal of USARIEM's research program is to reduce musculoskeletal injuries which would have the beneficial effect of reducing the need for NSAIDs among Soldiers. (Stripe -- Walter Reed Army Medical Center)
Analytical Bio-Chemistry Laboratories to Develop Liprostin Assays for Endovasc's Phase III Trial Jun 28, 2006
Endovasc's Liprostin is a liposome-encapsulated form of Prostaglandin E-1 (PGE-1) which is known to be a potent vasodilator and platelet inhibitor as well as an anti-inflammatory and anti-thrombotic agent. Endovasc has submitted its protocol for a phase IIIa clinical trial of Liprostin for the treatment of intermittent claudication, a symptom of Peripheral Arterial Disease, to the FDA. Intermittent claudication causes a cramping sensation in the legs that is present during exercise or walking... (Primezone Releases)
Estrogen Plays Different Role During Stress In Black And White Teens Jun 24, 2006
Estrogen influences blood pressure by releasing nitric oxide, a vasodilator, and by blunting the response of the sympathetic nervous system the fight or flight response as well as angiotensin II, a vasodilator ... In whites under stress, their estrogen levels are consistent so they are secreting vasodilators, they are blocking angiotensin and the sympathetic nervous system so the stress is not affecting them as much. (Science Daily)
Scientists Make Gains on Pain Prevention Jun 23, 2006
In the kidneys, vasodilator prostaglandins widen blood vessels, helping to maintain renal blood flow and to protect kidney function. According to Zambraski, one goal of the Army's research program is to reduce musculoskeletal injuries which would have the beneficial effect of reducing the need for non-steroidal anti-inflammatory drugs among soldiers. (The Journal -- National Naval Medical Center)
Stalled Sex Drive? New Drink Promises Jumpstart Feb 22, 2006
"The only thing I could see in here that would stimulate sexual functioning is caffeine because it improves the circulation a tiny bit. It's a vasodilator," Silverstein said. Boston University Medical Center's Dr. Caroline Apovian said that there could be some risks. (Click2Houston, TX)
Can diet curb my terrible headaches? Jan 18, 2006
This is why a single dose of caffeine can occasionally alleviate a headache caffeine is a vasodilator, and will help if your headache is linked to constriction in the blood vessels. If you ve found that this sometimes works for you, it s best to take your medicine in the form of a cup of tea, which is gentler on both head and body than coffee. (TimesOnline)
