Chemists Reach From The Molecular To The Real World With Creation Of 3-D DNA Crystals Sep 4, 2009
The researchers added sticky ends to these double helices, forming single-stranded overhangs to each double helix. Where these overhanging sticky ends were complementary, they bind together to link two double helices. (Science Daily)
ORDER OF WAR Set to Invade North America on September 22, 2009 Sep 3, 2009
This will be Square Enix's first release of a western-developed game outside of Japan and kicks off the launch of upcoming titles being developed through partnerships, including SUPREME COMMANDER 2 by Gas Powered Games and FRONT MISSION EVOLVED(TM) by Double Helix Games(TM) ... FRONT MISSION EVOLVED is a trademark of Square Enix Co., Ltd. SUPREME COMMANDER is a registered trademark of Square Enix, Inc. "Double Helix Games" is a trademark of Backbone Entertainment. (Yahoo! Wire -- Entertainment News)
Order of War Set to Invade Sep 3, 2009
This will be Square Enix's first release of a western-developed game outside of Japan and kicks off the launch of upcoming titles being developed through partnerships, including SUPREME COMMANDER 2 by Gas Powered Games and FRONT MISSION EVOLVED by Double Helix Games. These titles are part of Square Enix's commitment to offer a broader variety of games across different genres. (IGN PC Games)
Is The Milky Way Doomed To Be Destroyed By Galactic Bombardment? Probably Not, Study Says Sep 1, 2009
15, 2006) Astronomers report an unprecedented elongated double helix nebula near the center of our Milky Way. (Apr. (Science Daily)
G.I. Joe: Rise of the Cobra looks, sounds bad Aug 26, 2009
Developer: Double Helix ... Developer: Double Helix. (San Francisco Chronicle)
The stuff of life Aug 21, 2009
The third was the discovery of the double helix of DNA. ... Francis Crick and Jim Watson worked out the exquisite double helix in 1953 ... Her contribution to the discovery of the double helix was pivotal, but, ultimately, it was Crick and Watson's discovery. (BBC News -- Europe)
Tree testing Aug 21, 2009
"Our approach is scientific," said Kevin Hill from Double Helix Tracking Technologies, which tracks where wood comes from ... Kevin Hill, Double Helix Tracking Technologies. (BBC News -- Business)
DNA Scaffolding To Build Tiny Circuit Boards Aug 20, 2009
In this way, DNA nanostructures such as squares, triangles, and stars can be prepared that measure 100 to 150 nanometers on an edge and are as thick as the DNA double helix is wide. One roadblock to the use of DNA origami, however, is that the structures are made in saltwater solution whereas electronic circuits are created on surfaces, like a silicon wafer, so they can be integrated with other technologies. (Science Daily)
IBM Scientists Use DNA Scaffolding To Build Tiny Circuit Boards Aug 17, 2009
In this way, DNA nanostructures such as squares, triangles and stars can be prepared with dimensions of 100 - 150 nm on an edge and a thickness of the width of the DNA double helix. The lithographic templates were fabricated at IBM using traditional semiconductor techniques, the same used to make the chips found in today's computers, to etch out patterns. (PR Newswire)
Genetic code unravelled? Aug 11, 2009
The next-generation technique, led by the Rothberg Institute for Childhood Diseases Research in Connecticut, sequenced a sample given by James Watson, the Nobel laureate who co-discovered the DNA double helix. It dispenses with the laborious and costly cloning of the sample by bacteria, which is the precursor to the traditional sequencing method. (iAfrica.com)
Gene Transcribing Machine Takes Halting, Backsliding Trip Along The DNA Aug 10, 2009
These proteins, called RNA polymerase II (Pol II), slide along the DNA's double helix, reading the genetic code and transcribing it into RNA, which is used as a blueprint to build proteins or as a switch to regulate other genes. The measurements, which employed optical tweezers to grab both the polymerase and the end of a single molecule of DNA, are reported in the July 31 issue of the journal Science. (Science Daily)
Senate confirms Human Genome Project leader as new NIH director Aug 8, 2009
Francis Collins plays the customized "double helix" guitar he received while director of National Human Genome Research Institute during GQ Magazine's "Rock Stars of Science" photo shoot in New York, posing in sunglasses as part of a publicity campaign to bring celebrity to science. HEALTH UPDATES ON TWITTER. (USA Today -- News)
Square Enix at GamesCom Jul 30, 2009
From the creative minds of Square Enix and Double Helix Games, FRONT MISSION EVOLVED brings the classic FRONT MISSION franchise into an action-packed third-person shooter that gives players full control of a massive humanoid war machine;the wanzer. Players will battle through intense combat situations as they explore an immersive world in both the single player campaign and online multiplayer. (IGN PS2)
Light Shed On DNA Mechanisms Jul 23, 2009
ScienceDaily (July 22, 2009) By manipulating individual atoms in DNA and forming unique molecules, a Georgia State University researcher hopes to open new avenues in research towards better understanding the mechanisms of DNA replication and transcription, and perhaps leading to new treatments for diseases. Chemistry and chemical biology Professor Zhen Huang and his lab were able for the first time, to manipulate groups of molecules, called methyl and phosphate groups, in DNA that has been... (Science Daily)
Double Helix Strengthens its Strategic Pricing and Reimbursement Practice with Hire of Caryn Zieses Jul 21, 2009
(PRNewsFoto/Double Helix Consulting US) SCARSDALE, NY UNITED STATES ... (PRNewsFoto/Double Helix Consulting US) NEW YORK, NY UNITED STATES ... NEW YORK, July 20 /PRNewswire/ -- Double Helix Consulting US, a division of London-based Double Helix Development group, today announced the appointment of Caryn Zieses to the position of Senior Consultant. (PR Newswire)
Professor sheds light on DNA mechanisms Jul 18, 2009
" With DNA in humans, the genome is comprised of about 3 billion base pairs, which are part of DNA's "ladder" in the double helix which forms the code that causes certain genetic traits. If it takes a lot of energy to unwind DNA in order to duplicate, the process is slowed. On the other hand, if cellular dividing is too fast, DNA isn't copied properly with full length, which causes unhealthy cells to be formed. New research directions may open from the study, which could also have practical... (EurekAlert!)
New information about DNA repair mechanism could lead to better cancer drugs Jul 17, 2009
Using yeast cells, the scientists studied protein molecules that have an important role in homologous recombination, which is one way that cells repair breaks in the DNA double helix ... Srs2 is a helicase molecule a motor protein that's able to walk or slide along a strand of DNA and remove other proteins from DNA or separate the two strands of the twisted double helix ... Rad51's job in the cell is to promote the exchange of sequences between two related DNA molecules, which can be used to... (EurekAlert!)
Baylor researchers unravel mystery of DNA conformation Jul 14, 2009
Francis Crick and James Watson show the pair discussing with a rigid model of the famous double helix. The interaction represented produced the famous explanation of the structure of DNA, but the model pictured is a stiff snapshot of idealized DNA. As researchers from Baylor College of Medicine () and the University of Houston () note in a report that appears online in the journal Nucleic Acids Research, DNA is not a stiff or static. (EurekAlert!)
Researchers enlist DNA to bring carbon nanotubes' promise closer to reality Jul 9, 2009
The DuPont-Lehigh team says this could be related to DNA's ability to form a structure different from its usual double helix by wrapping around the CNTs. An alpha helix, like scotch tape wrapped around a pencil to form a tube, is a common shape seen in proteins, one of the main classes of biological molecules. (EurekAlert!)
New Research Unravels How Proteins Help Repair DNA Jun 24, 2009
They found that the proteins that initially recognize the damage amplify the distortion of the DNA around the damaged site by bending the DNA and separating the strands of the double helix. This makes it easier for the next protein to recognize and cut out the damaged portion of the DNA. The cells then patch up the empty space using the healthy half of the DNA as a model to repair the cell to its original state. (Science Daily)
First-ever link between missing DNA and cancer: study Jun 18, 2009
This undated illustration shows the DNA double helix. Scientists reported Wednesday the first link ever found between cancer and a type of genetic defect, called copy number variation, characterised by missing or extra bits of DNA.. (Yahoo! Asia News)
Oxymoron: Chilling out in the newsroom Jun 17, 2009
She is a marketer right down to her double helix. It is about as difficult as solving Fermat s Last Theorem. (Burlington Union, MA)
Simple Chemical System Created That Mimics DNA Jun 16, 2009
The group is also working to determine tPNA's structure, which could resemble the famous DNA double helix or look altogether different. Beyond origins of life questions, Ghadiri says the work also offers some distant but intriguing possibilities, especially considering that there are almost endless possibilities for creating systems similar to tPNA using differing chemical constituents. (Science Daily)
Analyzing DNA by Southern Blot Jun 16, 2009
Restriction enzymes will cut through the DNA double helix only in an area where a specific sequence of base pairs is found. Some restriction enzymes recognize a 4 base sequence, some recognize 6, some recognize 10 or more. (Suite101.com)
'Vocabulary parade' at Newton's Lincoln-Eliot School Jun 3, 2009
As one student ran across the stage holding a double helix, the audience chuckled at his choice of deoxyribonucleic acid as his word. As the helix made its exit, another crowd favorite, economy, took the stage. (Newton Tab, MA)
How Trivial DNA Changes Can Hurt Health Jun 2, 2009
When a gene is thus expressed, the strands of the DNA double helix separate and cellular machinery transcribes the nucleotide sequence along a single strand into a copy made of RNA. Then this messenger RNA (mRNA) transcript must often be edited into a briefer form before it is ready to be translated into a protein by ribosomes and smaller RNAs called transfer RNA (tRNA). As ribosomes ride along the mRNA, tRNAs arrive to deliver the encoded amino acids. (Scientific American)
Nine Concord residents graduate from CA Jun 2, 2009
He pointed to the 1953 publication of the first paper describing the double helix of DNA and the announcement, 50 years later, that the human genome had been sequenced. Lander, a leader in the international Human Genome Project, stepped outside his field to cite other examples: It took about five decades for the Internet as we know it today to germinate from its first idea, and, he added, just over 50 years passed between the Montgomery, Ala. (Concord Journal, MA)
Square Enix's E3 May 30, 2009
FRONT MISSION EVOLVED Developer: Double Helix Games Publisher: Square Enix, Inc. Platforms: PLAYSTATION 3/Xbox 360/Windows PC Genre: Third-Person Shooter ESRB: Not Yet Rated Ship Date: TBA. From the creative minds of Square Enix and Double Helix Games, FRONT MISSION EVOLVED brings the classic FRONT MISSION franchise into an action-packed third-person shooter that gives players full control of a massive humanoid war machine;the wanzer. (IGN PS2)
Shared Genetic Link Between Dental Disease Periodontitis And Heart Attack Discovered May 26, 2009
Antisense RNA is complementary to the mRNA, and is often carried by the reverse strand, the 'anti-sense' strand of the DNA double helix. This strand does not encode for a protein, but can bind specifically to the messenger RNA to form a duplex. (Science Daily)
Scientists May Have Found How Life Began May 15, 2009
Genetic information in living organisms today is held in deoxyribonucleic acid (DNA), the famous "double helix" molecule of sugar, phosphate and a base. But DNA is too sophisticated to have popped up in an instant, and one avenue of thought says its single-stranded cousin, ribonucleic acid, or RNA, came first. (Fox News)
Hints of a helix, circa 1947 May 13, 2009
These results, along with Erwin Chargaff's 1950 discovery that DNA contains equal amounts of adenine and thymine and equal amounts of cytosine and guanine, paved the way for James Watson and Francis Crick's discovery that the molecule is, in fact, a double helix. As Watson put it in The Double Helix (1970): "A rereading of J.M. Gulland's and D.O. Jordan's papers... made me finally realize the strength of their conclusion that a large fraction, if not all, of the bases formed hydrogen bonds to... (The Scientist)
Silent Hill Homecoming May 10, 2009
But mostly, in the hands of a new American developer (Double Helix Games), Homecoming tries way too hard to be scary ... It s clear that Double Helix loves the series and wants to be part of it, but Homecoming plays like a hollow imitation of the first three installments, complete with the obligatory hospital level with the usual disfigured, busty nurses. (Suite101.com)
Lithium may help radiation target cancer, spare healthy tissue May 5, 2009
One of the most serious types of DNA damage is the chromosomal double-stranded break (DSB), in which both strands of the double helix are severed. Even a single unrepaired DSB can be lethal to a cell. (EurekAlert!)
Learning more about the human makeup Apr 30, 2009
Friday, April 24, the Algona High School biology classes celebrated DNA Day, commemorating the completion of the Human Genome Project in April 2003, and the discovery of DNA's double helix. Biology teacher Steve Young at Algona High School had students in his class extract DNA from kiwi fruit earlier in the week. (Algona Upper Des Moines, IA)
Genetic switch potential key to new class of antibiotics Apr 18, 2009
When the riboswitch twists into the well-known double helix structure, the RNA composing part of its structure aligns the bases in its chain such that they stack on top of each other, adding to their stability ... The order of bases in a typical aptamer domain of the riboswitch causes the chain to fold back and bind to itself to form a double helix that ends in a loop like a lollipop. (EurekAlert!)
New Nucleotide Could Revolutionize Epigenetics Apr 17, 2009
The rise of epigenetics in the past decade has drawn attention to a fifth nucleotide, 5-methylcytosine (5-mC), that sometimes replaces cytosine in the famous DNA double helix to regulate which genes are expressed ... Chemical structure of cytosine, one of the four nucleotide bases that make up DNA. New research shows that two additional nucleotides -- 5-methylcytosine and 5-hydroxymethylcytosine -- can sometimes replace cytosine in the DNA double helix to regulate which genes are expressed. (Science Daily)
Process By Which Cells 'Hide' Potentially Dangerous DNA Segments Explained Apr 12, 2009
In a report that appears in the journal Molecular Cell, they show that the assembly of heterochromatin depends on the strength with which a protein called Chp1 binds to a specific target site located on a histone protein that has attached to the double helix. RNAi's role in heterochromatin formation. (Science Daily)
World libraries build online intellectual cathedral Apr 10, 2009
London's Wellcome Collection is to provide anatomical drawings and scientific texts including Francis Crick's first sketch of the DNA double helix. Guardian News & Media. (Sydney Morning Herald -- Technology)
CSHL researchers explain process by which cells 'hide' potentially dangerous DNA segments Apr 10, 2009
In a report that appears online on April 9th in the journal Molecular Cell, they show that the assembly of heterochromatin depends on the strength with which a protein called Chp1 binds to a specific target site located on a histone protein that has attached to the double helix. RNAi's role in heterochromatin formation. (EurekAlert!)
Era of personalised medicine awaits Apr 9, 2009
These are arranged in a double helix, whose elegant structure was first described by Crick and Watson in 1953. At the time, their discovery barely made headlines. (BBC News -- Science)
Chemists Create Bipedal, Autonomous DNA Walker Apr 6, 2009
In nature, single strands of DNA each containing four molecules, or bases, attached to backbone self-assemble to form a double helix when their bases match up. Kinesin is a molecular motor that carries various cargoes from one place in the cell to another. (Science Daily)
Discovery May Result In New Test To Determine Predisposition To Cancer Mar 26, 2009
The assay determines the efficiency of the repair mechanism when DNA suffers a double-strand break, when both strands in the double helix are severed. These breaks cause genetic instability and are particularly dangerous because they can lead to genome rearrangements or deletions of certain genes that, when gone, result in cancer. (Science Daily)
DNA Shape Is Constrained By Evolution: Structural Approach To Exploring DNA Mar 20, 2009
Genomic DNA is shown streaming out from a chromosome (left), progressively unfolding as chromatin, the 30-nm filament, nucleosomes, the DNA double helix, and finally the letters representing the nucleotide sequence. Although it is the molecular topography of the DNA helix that is recognized by proteins, current methods of genome analysis mostly focus on the order of nucleotides. (Science Daily)
Fishing For Microdeletions That Predispose An Embryo To Develop Cancer Syndromes In Later Life Mar 19, 2009
The strands of DNA that twist together to form the double helix structure are made up of lots of small sections called nucleotides. The nucleotides are made up of the four DNA bases adenine, thymine, guanine and cytosine (or A,T,C,G). (Science Daily)
Scripps opens new home in Jupiter Feb 27, 2009
The spire shaped like a DNA double helix atop one of the three buildings symbolized not just the promise of new scientific breakthroughs, but also hope for a sorely needed boost to Florida s ailing economy. In 2003, just after the real estate boom had begun, former Gov. Jeb Bush announced that La Jolla, Calif. (South Florida Business Journal, FL)
How to hang a cat by its DNA tale Feb 26, 2009
A kind of modern-day portrait with a double helix twist. Set in orange and red tones, the portrait looks like an abstract work of art to the untrained eye. (The Age, Australia -- National)
Alien life 'may exist among us' Feb 18, 2009
" The molecule is essentially a modified version of our own DNA double helix - but with six "letters" in its genetic alphabet, instead of four. These nucleotides pair up in strands, which can replicate, though only with the help of polymerase enzymes and heat. "Sometimes mistakes are made in pairing and these mistakes are maintained in the next generation - it is evolving," said Prof Brenner. "The next step is to apply natural selection to it, to see if it can evolve under selective pressure.... (BBC News -- Science)
Form Follows Sequence Feb 7, 2009
Ever since James Watson and Francis Crick solved the double helix structure of dna in 1953, biology's most formidable structural challenge has been the "protein folding problem" - learning how nature gets from a gene, a length of dna that encodes the order of amino-acid residues in a string, to a working protein, that same string intricately folded into all the pockets and creases and knobs essential to the physics and chemistry of life. While protein structures are being collected at a steadily... (FirstScience.com)
